Immunogenomics guided design of immunomodulatory multi-epitope subunit vaccine against the SARS-CoV-2 new variants, and its validation through in silico cloning and immune simulation
出版年份 2021 全文链接
标题
Immunogenomics guided design of immunomodulatory multi-epitope subunit vaccine against the SARS-CoV-2 new variants, and its validation through in silico cloning and immune simulation
作者
关键词
SARS-CoV-2, New variant, Vaccine designing, In silico, cloning, Immune simulation
出版物
COMPUTERS IN BIOLOGY AND MEDICINE
Volume 133, Issue -, Pages 104420
出版商
Elsevier BV
发表日期
2021-04-24
DOI
10.1016/j.compbiomed.2021.104420
参考文献
相关参考文献
注意:仅列出部分参考文献,下载原文获取全部文献信息。- COVID-19 and Toll-Like Receptor 4 (TLR4): SARS-CoV-2 May Bind and Activate TLR4 to Increase ACE2 Expression, Facilitating Entry and Causing Hyperinflammation
- (2021) Mohamed M. Aboudounya et al. MEDIATORS OF INFLAMMATION
- New variant of SARS-CoV-2 in UK causes surge of COVID-19
- (2021) Tony Kirby Lancet Respiratory Medicine
- Higher infectivity of the SARS‐CoV‐2 new variants is associated with K417N/T, E484K, and N501Y mutants: An insight from structural data
- (2021) Abbas Khan et al. JOURNAL OF CELLULAR PHYSIOLOGY
- Development of epitope‐based peptide vaccine against novel coronavirus 2019 (SARS‐COV‐2): Immunoinformatics approach
- (2020) Manojit Bhattacharya et al. JOURNAL OF MEDICAL VIROLOGY
- Genomic characterisation and epidemiology of 2019 novel coronavirus: implications for virus origins and receptor binding
- (2020) Roujian Lu et al. LANCET
- Epidemiological and clinical characteristics of 99 cases of 2019 novel coronavirus pneumonia in Wuhan, China: a descriptive study
- (2020) Nanshan Chen et al. LANCET
- Clinical features of patients infected with 2019 novel coronavirus in Wuhan, China
- (2020) Chaolin Huang et al. LANCET
- A new coronavirus associated with human respiratory disease in China
- (2020) Fan Wu et al. NATURE
- A Novel Coronavirus from Patients with Pneumonia in China, 2019
- (2020) Na Zhu et al. NEW ENGLAND JOURNAL OF MEDICINE
- Cryo-EM structure of the 2019-nCoV spike in the prefusion conformation
- (2020) Daniel Wrapp et al. SCIENCE
- Preliminary Identification of Potential Vaccine Targets for the COVID-19 Coronavirus (SARS-CoV-2) Based on SARS-CoV Immunological Studies
- (2020) Syed Faraz Ahmed et al. Viruses-Basel
- SARS-CoV-2 Receptor ACE2 Is an Interferon-Stimulated Gene in Human Airway Epithelial Cells and Is Detected in Specific Cell Subsets across Tissues
- (2020) Carly G.K. Ziegler et al. CELL
- SARS-CoV-2 Cell Entry Depends on ACE2 and TMPRSS2 and Is Blocked by a Clinically Proven Protease Inhibitor
- (2020) Markus Hoffmann et al. CELL
- Heightened Innate Immune Responses in the Respiratory Tract of COVID-19 Patients
- (2020) Zhuo Zhou et al. Cell Host & Microbe
- Epitope-based vaccine design: a comprehensive overview of bioinformatics approaches
- (2020) Sepideh Parvizpour et al. DRUG DISCOVERY TODAY
- In silico studies on the comparative characterization of the interactions of SARS‐CoV‐2 spike glycoprotein with ACE‐2 receptor homologs and human TLRs
- (2020) Abhigyan Choudhury et al. JOURNAL OF MEDICAL VIROLOGY
- Structure of the SARS-CoV-2 spike receptor-binding domain bound to the ACE2 receptor
- (2020) Jun Lan et al. NATURE
- Phylogenetic Analysis and Structural Perspectives of RNA-Dependent RNA-Polymerase Inhibition from SARs-CoV-2 with Natural Products
- (2020) Abbas Khan et al. Interdisciplinary Sciences-Computational Life Sciences
- Structural Insights into the mechanism of RNA recognition by the N-terminal RNA-binding domain of the SARS-CoV-2 nucleocapsid phosphoprotein
- (2020) Abbas Khan et al. Computational and Structural Biotechnology Journal
- Immunoinformatic Analysis of T- and B-Cell Epitopes for SARS-CoV-2 Vaccine Design
- (2020) Dongliang Wang et al. Vaccines
- Immunoinformatics characterization of SARS-CoV-2 spike glycoprotein for prioritization of epitope based multivalent peptide vaccine
- (2020) Saba Ismail et al. JOURNAL OF MOLECULAR LIQUIDS
- Immunodominant regions prediction of nucleocapsid protein for SARS-CoV-2 early diagnosis: a bioinformatics and immunoinformatics study
- (2020) Yufeng Dai et al. Pathogens and Global Health
- From SARS to MERS, Thrusting Coronaviruses into the Spotlight
- (2019) Zhiqi Song et al. Viruses-Basel
- Protein Solubility Predictions Using the CamSol Method in the Study of Protein Homeostasis
- (2019) Pietro Sormanni et al. Cold Spring Harbor Perspectives in Biology
- Adaptation and memory in immune responses
- (2019) Gioacchino Natoli et al. NATURE IMMUNOLOGY
- Structural vaccinology considerations for in silico designing of a multi-epitope vaccine
- (2018) Manica Negahdaripour et al. INFECTION GENETICS AND EVOLUTION
- Computational identification, characterization and validation of potential antigenic peptide vaccines from hrHPVs E6 proteins using immunoinformatics and computational systems biology approaches
- (2018) Abbas Khan et al. PLoS One
- Human β-defensin 2 plays a regulatory role in innate antiviral immunity and is capable of potentiating the induction of antigen-specific immunity
- (2018) Ju Kim et al. Virology Journal
- The Immune Epitope Database (IEDB): 2018 update
- (2018) Randi Vita et al. NUCLEIC ACIDS RESEARCH
- A Review on T Cell Epitopes Identified Using Prediction and Cell-Mediated Immune Models for Mycobacterium tuberculosis and Bordetella pertussis
- (2018) Yuan Tian et al. Frontiers in Immunology
- The ClusPro web server for protein–protein docking
- (2017) Dima Kozakov et al. Nature Protocols
- PEP-FOLD3: fasterde novostructure prediction for linear peptides in solution and in complex
- (2016) Alexis Lamiable et al. NUCLEIC ACIDS RESEARCH
- Structure, Function, and Evolution of Coronavirus Spike Proteins
- (2016) Fang Li Annual Review of Virology
- Middle East Respiratory Syndrome Coronavirus: Another Zoonotic Betacoronavirus Causing SARS-Like Disease
- (2015) Jasper F. W. Chan et al. CLINICAL MICROBIOLOGY REVIEWS
- Inferring the hosts of coronavirus using dual statistical models based on nucleotide composition
- (2015) Qin Tang et al. Scientific Reports
- Cholera Toxin B: One Subunit with Many Pharmaceutical Applications
- (2015) Keegan Baldauf et al. Toxins
- A novel multi-epitope peptide vaccine against cancer: An in silico approach
- (2014) Navid Nezafat et al. JOURNAL OF THEORETICAL BIOLOGY
- PTRAJ and CPPTRAJ: Software for Processing and Analysis of Molecular Dynamics Trajectory Data
- (2013) Daniel R. Roe et al. Journal of Chemical Theory and Computation
- Routine Microsecond Molecular Dynamics Simulations with AMBER on GPUs. 2. Explicit Solvent Particle Mesh Ewald
- (2013) Romelia Salomon-Ferrer et al. Journal of Chemical Theory and Computation
- Dipeptidyl peptidase 4 is a functional receptor for the emerging human coronavirus-EMC
- (2013) V. Stalin Raj et al. NATURE
- GalaxyWEB server for protein structure prediction and refinement
- (2012) J. Ko et al. NUCLEIC ACIDS RESEARCH
- Immune system simulation online
- (2011) N. Rapin et al. BIOINFORMATICS
- Adaptive immunity
- (2010) Francisco A. Bonilla et al. JOURNAL OF ALLERGY AND CLINICAL IMMUNOLOGY
- Assessing the Performance of the MM/PBSA and MM/GBSA Methods. 1. The Accuracy of Binding Free Energy Calculations Based on Molecular Dynamics Simulations
- (2010) Tingjun Hou et al. Journal of Chemical Information and Modeling
- VirulentPred: a SVM based prediction method for virulent proteins in bacterial pathogens
- (2008) Aarti Garg et al. BMC BIOINFORMATICS
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