Kallikrein-related peptidases (KLKs) as emerging therapeutic targets: focus on prostate cancer and skin pathologies
出版年份 2016 全文链接
标题
Kallikrein-related peptidases (KLKs) as emerging therapeutic targets: focus on prostate cancer and skin pathologies
作者
关键词
-
出版物
EXPERT OPINION ON THERAPEUTIC TARGETS
Volume 20, Issue 7, Pages 801-818
出版商
Informa Healthcare
发表日期
2016-01-27
DOI
10.1517/14728222.2016.1147560
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注意：仅列出部分参考文献，下载原文获取全部文献信息。- Intratherapeutic Biokinetic Measurements, Dosimetry Parameter Estimates, and Monitoring of Treatment Efficacy Using Cerenkov Luminescence Imaging in Preclinical Radionuclide Therapy
- (2015) O. V. Timmermand et al. JOURNAL OF NUCLEAR MEDICINE
- Unleashing the therapeutic potential of human kallikrein-related serine proteases
- (2015) Ioannis Prassas et al. NATURE REVIEWS DRUG DISCOVERY
- KLK5 Inactivation Reverses Cutaneous Hallmarks of Netherton Syndrome
- (2015) Laetitia Furio et al. PLoS Genetics
- Netherton syndrome: defective kallikrein inhibition in the skin leads to skin inflammation and allergy
- (2014) Laetitia Furio et al. BIOLOGICAL CHEMISTRY
- Mechanism-based selection of a potent kallikrein-related peptidase 7 inhibitor from a versatile library based on the sunflower trypsin inhibitor SFTI-1
- (2014) Simon J. de Veer et al. BIOPOLYMERS
- SPINK5 knockdown in organotypic human skin culture as a model system for Netherton syndrome: effect of genetic inhibition of serine proteases kallikrein 5 and kallikrein 7
- (2014) Shirley Wang et al. EXPERIMENTAL DERMATOLOGY
- Targeting metastatic castration-resistant prostate cancer: mechanisms of progression and novel early therapeutic approaches
- (2014) Vittore Cereda et al. EXPERT OPINION ON INVESTIGATIONAL DRUGS
- Targeting kallikrein-related peptidases in prostate cancer
- (2014) Konstantinos Mavridis et al. EXPERT OPINION ON THERAPEUTIC TARGETS
- Vaccine immunotherapy for prostate cancer: from mice to men
- (2014) David M. Lubaroff et al. IMMUNOLOGIC RESEARCH
- Structure-Function Analyses of Human Kallikrein-related Peptidase 2 Establish the 99-Loop as Master Regulator of Activity
- (2014) Wolfgang Skala et al. JOURNAL OF BIOLOGICAL CHEMISTRY
- Transgenic kallikrein 5 mice reproduce major cutaneous and systemic hallmarks of Netherton syndrome
- (2014) Laetitia Furio et al. JOURNAL OF EXPERIMENTAL MEDICINE
- Toward the First Class of Suicide Inhibitors of Kallikreins Involved in Skin Diseases
- (2014) Xiao Tan et al. JOURNAL OF MEDICINAL CHEMISTRY
- Preclinical imaging of kallikrein-related peptidase 2 (hK2) in prostate cancer with a 111In-radiolabelled monoclonal antibody, 11B6
- (2014) Oskar Vilhelmsson Timmermand et al. EJNMMI Research
- Selection of 2′F-modified RNA aptamers against prostate-specific antigen and their evaluation for diagnostic and therapeutic applications
- (2013) M. Svobodova et al. ANALYTICAL AND BIOANALYTICAL CHEMISTRY
- 1,2,4-Triazole derivatives as transient inactivators of kallikreins involved in skin diseases
- (2013) Xiao Tan et al. BIOORGANIC & MEDICINAL CHEMISTRY LETTERS
- A novel IgE antibody targeting the prostate-specific antigen as a potential prostate cancer therapy
- (2013) Tracy R Daniels-Wells et al. BMC CANCER
- Netherton syndrome: skin inflammation and allergy by loss of protease inhibition
- (2013) Alain Hovnanian CELL AND TISSUE RESEARCH
- Structural Optimization, Biological Evaluation, and Application of Peptidomimetic Prostate Specific Antigen Inhibitors
- (2013) Maya B. Kostova et al. JOURNAL OF MEDICINAL CHEMISTRY
- Paclitaxel Resistance and Multicellular Spheroid Formation Are Induced by Kallikrein-Related Peptidase 4 in Serous Ovarian Cancer Cells in an Ascites Mimicking Microenvironment
- (2013) Ying Dong et al. PLoS One
- Molecular circuit involving KLK4 integrates androgen and mTOR signaling in prostate cancer
- (2013) Y. Jin et al. PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA
- Structure of plasma and tissue kallikreins
- (2013) Monika Pathak et al. THROMBOSIS AND HAEMOSTASIS
- Human kallikrein 2 (KLK2) promotes prostate cancer cell growth via function as a modulator to promote the ARA70-enhanced androgen receptor transactivation
- (2013) Zhiqun Shang et al. TUMOR BIOLOGY
- Epigenetic regulation of kallikrein-related peptidases: there is a whole new world out there
- (2012) Maria D. Pasic et al. BIOLOGICAL CHEMISTRY
- One round of SELEX for the generation of DNA aptamers directed against KLK6
- (2012) Steve Arnold et al. BIOLOGICAL CHEMISTRY
- Kallikrein-related peptidases in prostate, breast, and ovarian cancers: from pathobiology to clinical relevance
- (2012) Margaritis Avgeris et al. BIOLOGICAL CHEMISTRY
- Pro-angiogenic effect of human kallikrein-related peptidase 12 (KLK12) in lung endothelial cells does not depend on kinin-mediated activation of B2 receptor
- (2012) Thomas Kryza et al. BIOLOGICAL CHEMISTRY
- Isomannide derivatives as new class of inhibitors for human kallikrein 7
- (2012) Renato F. Freitas et al. BIOORGANIC & MEDICINAL CHEMISTRY LETTERS
- Targeting Free Prostate-Specific Antigen for In Vivo Imaging of Prostate Cancer Using a Monoclonal Antibody Specific for Unique Epitopes Accessible on Free Prostate-Specific Antigen Alone
- (2012) Susan Evans-Axelsson et al. CANCER BIOTHERAPY AND RADIOPHARMACEUTICALS
- Kallikrein-related peptidases (KLKs): a gene family of novel cancer biomarkers
- (2012) Christos K. Kontos et al. CLINICAL CHEMISTRY AND LABORATORY MEDICINE
- Prostate cancer vaccines in clinical trials
- (2012) David M Lubaroff Expert Review of Vaccines
- Prospective, Randomized, Double-Blind, Vehicle Controlled, Multicenter Phase IIb Clinical Trial of the Pore Forming Protein PRX302 for Targeted Treatment of Symptomatic Benign Prostatic Hyperplasia
- (2012) Mostafa M. Elhilali et al. JOURNAL OF UROLOGY
- Cancer immunotherapy: a paradigm shift for prostate cancer treatment
- (2012) Dev Karan et al. Nature Reviews Urology
- Targeting the kallikrein-related peptidases for drug development
- (2012) Georgia Sotiropoulou et al. TRENDS IN PHARMACOLOGICAL SCIENCES
- Imaging Androgen Receptor Signaling with a Radiotracer Targeting Free Prostate-Specific Antigen
- (2012) David Ulmert et al. Cancer Discovery
- Protease-Activated Drug Development
- (2012) Ki Young Choi et al. Theranostics
- Biological evaluation and docking studies of natural isocoumarins as inhibitors for human kallikrein 5 and 7
- (2011) Thiago S.P. Teixeira et al. BIOORGANIC & MEDICINAL CHEMISTRY LETTERS
- Human kallikrein 4 signal peptide induces cytotoxic T cell responses in healthy donors and prostate cancer patients
- (2011) Ray Wilkinson et al. CANCER IMMUNOLOGY IMMUNOTHERAPY
- Inhibition of Transcription Factor Specificity Protein 1 Alters the Gene Expression Profile of Keratinocytes Leading to Upregulation of Kallikrein-Related Peptidases and Thymic Stromal Lymphopoietin
- (2011) Lianghua Bin et al. JOURNAL OF INVESTIGATIVE DERMATOLOGY
- Development of a Peptide–Drug Conjugate for Prostate Cancer Therapy
- (2011) Wanyi Tai et al. MOLECULAR PHARMACEUTICS
- Mastering the Canonical Loop of Serine Protease Inhibitors: Enhancing Potency by Optimising the Internal Hydrogen Bond Network
- (2011) Joakim E. Swedberg et al. PLoS One
- Kallikrein-related peptidase 4 gene (KLK4) in prostate tumors: Quantitative expression analysis and evaluation of its clinical significance
- (2011) Margaritis Avgeris et al. PROSTATE
- Synergistic tumor growth-inhibitory effect of the prostate-specific antigen-activated fusion peptide BSD352 for prostate cancer therapy
- (2010) Bin Li et al. ANTI-CANCER DRUGS
- Natural and synthetic inhibitors of kallikrein-related peptidases (KLKs)
- (2010) Peter Goettig et al. BIOCHIMIE
- Kallikrein-related peptidase genes as promising biomarkers for prognosis and monitoring of human malignancies
- (2010) Margaritis Avgeris et al. BIOLOGICAL CHEMISTRY
- Natural and engineered kallikrein inhibitors: an emerging pharmacopoeia
- (2010) Joakim E. Swedberg et al. BIOLOGICAL CHEMISTRY
- Selection of DNA aptamer against prostate specific antigen using a genetic algorithm and application to sensing
- (2010) Nasa Savory et al. BIOSENSORS & BIOELECTRONICS
- Molecular mechanism of kallikrein-related peptidase 8/neuropsin-induced hyperkeratosis in inflamed skin
- (2010) K. Shingaki et al. BRITISH JOURNAL OF DERMATOLOGY
- Kallikreins on Steroids: Structure, Function, and Hormonal Regulation of Prostate-Specific Antigen and the Extended Kallikrein Locus
- (2010) Mitchell G. Lawrence et al. ENDOCRINE REVIEWS
- Phase 1 and 2 Studies Demonstrate the Safety and Efficacy of Intraprostatic Injection of PRX302 for the Targeted Treatment of Lower Urinary Tract Symptoms Secondary to Benign Prostatic Hyperplasia
- (2010) Samuel R. Denmeade et al. EUROPEAN UROLOGY
- Prognostic value and biological role of the kallikrein-related peptidases in human malignancies
- (2010) Konstantinos Mavridis et al. Future Oncology
- Overall Survival Analysis of a Phase II Randomized Controlled Trial of a Poxviral-Based PSA-Targeted Immunotherapy in Metastatic Castration-Resistant Prostate Cancer
- (2010) Philip W. Kantoff et al. JOURNAL OF CLINICAL ONCOLOGY
- Kallikrein Expression and Cathelicidin Processing Are Independently Controlled in Keratinocytes by Calcium, Vitamin D3, and Retinoic Acid
- (2010) Shin Morizane et al. JOURNAL OF INVESTIGATIVE DERMATOLOGY
- TLR2 Expression Is Increased in Rosacea and Stimulates Enhanced Serine Protease Production by Keratinocytes
- (2010) Kenshi Yamasaki et al. JOURNAL OF INVESTIGATIVE DERMATOLOGY
- Aptamers as therapeutics
- (2010) Anthony D. Keefe et al. NATURE REVIEWS DRUG DISCOVERY
- Sipuleucel-T Immunotherapy for Castration-Resistant Prostate Cancer
- (2010) Philip W. Kantoff et al. NEW ENGLAND JOURNAL OF MEDICINE
- Selection of RNA aptamers specific to active prostate-specific antigen
- (2009) Sujin Jeong et al. BIOTECHNOLOGY LETTERS
- Immunologic and prognostic factors associated with overall survival employing a poxviral-based PSA vaccine in metastatic castrate-resistant prostate cancer
- (2009) James L. Gulley et al. CANCER IMMUNOLOGY IMMUNOTHERAPY
- Phase I Clinical Trial of an Adenovirus/Prostate-Specific Antigen Vaccine for Prostate Cancer: Safety and Immunologic Results
- (2009) D. M. Lubaroff et al. CLINICAL CANCER RESEARCH
- Prostvac-VF: a vector-based vaccine targeting PSA in prostate cancer
- (2009) Ravi A Madan et al. EXPERT OPINION ON INVESTIGATIONAL DRUGS
- Kallikrein-related peptidase-4 initiates tumorâstroma interactions in prostate cancer through protease-activated receptor-1
- (2009) Wenbin Wang et al. INTERNATIONAL JOURNAL OF CANCER
- Functional Roles of Human Kallikrein-related Peptidases
- (2009) Georgia Sotiropoulou et al. JOURNAL OF BIOLOGICAL CHEMISTRY
- Direct intra-tumoral injection of zinc-acetate halts tumor growth in a xenograft model of prostate cancer
- (2009) Maulik R Shah et al. JOURNAL OF EXPERIMENTAL & CLINICAL CANCER RESEARCH
- Kallikrein 5 induces atopic dermatitis–like lesions through PAR2-mediated thymic stromal lymphopoietin expression in Netherton syndrome
- (2009) Anaïs Briot et al. JOURNAL OF EXPERIMENTAL MEDICINE
- Structures and specificity of the human kallikrein-related peptidases KLK 4, 5, 6, and 7
- (2008) Mekdes Debela et al. BIOLOGICAL CHEMISTRY
- Human tissue kallikreins as promiscuous modulators of homeostatic skin barrier functions
- (2008) Azza Eissa et al. BIOLOGICAL CHEMISTRY
- Kallikreins as microRNA targets: an in silico and experimental-based analysis
- (2008) Tsz-fung F. Chow et al. BIOLOGICAL CHEMISTRY
- A completed KLK activome profile: investigation of activation profiles of KLK9, 10, and 15
- (2008) Hyesook Yoon et al. BIOLOGICAL CHEMISTRY
- Tissue Prostate-Specific Antigen Facilitates Refractory Prostate Tumor Progression via Enhancing ARA70-Regulated Androgen Receptor Transactivation
- (2008) Y. Niu et al. CANCER RESEARCH
- Kallikrein-related peptidases
- (2008) Å. Lundwall et al. CELLULAR AND MOLECULAR LIFE SCIENCES
- Potent and Selective Peptidyl Boronic Acid Inhibitors of the Serine Protease Prostate-Specific Antigen
- (2008) Aaron M. LeBeau et al. CHEMISTRY & BIOLOGY
- Major Role of Human KLK14 in Seminal Clot Liquefaction
- (2008) Nashmil Emami et al. JOURNAL OF BIOLOGICAL CHEMISTRY
- Prostate-Specific Kallikreins-2 and -4 Enhance the Proliferation of DU-145 Prostate Cancer Cells through Protease-Activated Receptors-1 and -2
- (2008) G. J. Mize et al. MOLECULAR CANCER RESEARCH
- Novel small molecule inhibitors for prostate‐specific antigen
- (2008) Hannu Koistinen et al. PROSTATE
- Activation profiles of human kallikrein-related peptidases by proteases of the thrombostasis axis
- (2008) Hyesook Yoon et al. PROTEIN SCIENCE
- Activation of Proteinase-Activated Receptor-2 by Human Kallikrein-Related Peptidases
- (2007) Kristina Stefansson et al. JOURNAL OF INVESTIGATIVE DERMATOLOGY
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