Chlorpyrifos pesticide promotes oxidative stress and increases inflammatory states in BV-2 microglial cells: A role in neuroinflammation

Environmental neurotoxicant-induced dopaminergic neurodegeneration: a potential link to impaired neuroinflammatory mechanisms

(2019) Arthi Kanthasamy et al.   PHARMACOLOGY & THERAPEUTICS

NLRP inflammasome as a key role player in the pathogenesis of environmental toxicants

(2019) Milad Moloudizargari et al.   LIFE SCIENCES

Evaluation of chlorpyrifos toxicity through a 28-day study: Cholinesterase activity, oxidative stress responses, parent compound/metabolite levels, and primary DNA damage in blood and brain tissue of adult male Wistar rats

(2018) Nevenka Kopjar et al.   CHEMICO-BIOLOGICAL INTERACTIONS

Paraquat-induced inflammatory response of microglia through HSP60/TLR4 signaling

(2018) Y Sun et al.   HUMAN & EXPERIMENTAL TOXICOLOGY

The Neuroinflammatory Phenotype in a Mouse Model of Gulf War Illness is Unrelated to Brain Regional Levels of Acetylcholine as Measured by Quantitative HILIC-UPLC-MS/MS

(2018) Julie V Miller et al.   TOXICOLOGICAL SCIENCES

Taurine protects dopaminergic neurons in a mouse Parkinson’s disease model through inhibition of microglial M1 polarization

(2018) Yuning Che et al.   Cell Death & Disease

Differential Regulation of Resolution in Inflammation induced by Amyloid-β42 and Lipopolysaccharides in Human Microglia

(2018) Mingqin Zhu et al.   JOURNAL OF ALZHEIMERS DISEASE

The link of organophosphorus pesticides with neurodegenerative and neurodevelopmental diseases based on evidence and mechanisms

(2018) Sara Mostafalou et al.   TOXICOLOGY

Neurotoxicity in acute and repeated organophosphate exposure

(2018) Sean X. Naughton et al.   TOXICOLOGY

Sex-dependent effects of developmental exposure to different pesticides on spatial learning. The role of induced neuroinflammation in the hippocampus

(2017) Belén Gómez-Giménez et al.   FOOD AND CHEMICAL TOXICOLOGY

Developmental neurotoxicity of the organophosphorus insecticide chlorpyrifos: from clinical findings to preclinical models and potential mechanisms

(2017) Richard D. Burke et al.   JOURNAL OF NEUROCHEMISTRY

Corticosterone primes the neuroinflammatory response to Gulf War Illness-relevant organophosphates independently of acetylcholinesterase inhibition

(2017) Alicia R. Locker et al.   JOURNAL OF NEUROCHEMISTRY

Rifampicin inhibits rotenone-induced microglial inflammation via enhancement of autophagy

(2017) Yanran Liang et al.   NEUROTOXICOLOGY

Microglia in CNS development: Shaping the brain for the future

(2017) Coralie-Anne Mosser et al.   PROGRESS IN NEUROBIOLOGY

The role of oxidative stress in organophosphate and nerve agent toxicity

(2016) Jennifer N. Pearson et al.   Annals of the New York Academy of Sciences

Nod-like receptor pyrin containing 3 (NLRP3) in the post-mortem frontal cortex from patients with bipolar disorder: A potential mediator between mitochondria and immune-activation

(2016) Helena Kyunghee Kim et al.   JOURNAL OF PSYCHIATRIC RESEARCH

ROS-dependent genotoxicity, cell cycle perturbations and apoptosis in mouse bone marrow cells exposed to formulated mixture of cypermethrin and chlorpyrifos

(2016) Lalit K. S. Chauhan et al.   MUTAGENESIS

Chronic dietary chlorpyrifos causes long-term spatial memory impairment and thigmotaxic behavior

(2016) Caridad López-Granero et al.   NEUROTOXICOLOGY

The protective role of alpha-lipoic acid on long-term exposure of rats to the combination of chlorpyrifos and deltamethrin pesticides

(2016) Chidiebere Uchendu et al.   TOXICOLOGY AND INDUSTRIAL HEALTH

The suitability of BV2 cells as alternative model system for primary microglia cultures or for animal experiments examining brain inflammation

(2016) Anja Henn   ALTEX-Alternatives to Animal Experimentation

Oxidative stress, mitochondrial dysfunction and neurodegenerative diseases; a mechanistic insight

(2015) Aashiq Hussain Bhat et al.   BIOMEDICINE & PHARMACOTHERAPY

Molecular mechanisms regulating NLRP3 inflammasome activation

(2015) Eun-Kyeong Jo et al.   Cellular & Molecular Immunology

Systemic inflammation and microglial activation: systematic review of animal experiments

(2015) Inge C.M. Hoogland et al.   Journal of Neuroinflammation

Repeated exposure to chlorpyrifos leads to prolonged impairments of axonal transport in the living rodent brain

(2015) Caterina M. Hernandez et al.   NEUROTOXICOLOGY

Chlorpyrifos induces NLRP3 inflammasome and pyroptosis/apoptosis via mitochondrial oxidative stress in human keratinocyte HaCaT cells

(2015) Yoonjeong Jang et al.   TOXICOLOGY

Inflammation and Neuroprotection in Traumatic Brain Injury

(2015) Kara N. Corps et al.   JAMA Neurology

Alterations in Immune Cells and Mediators in the Brain: It's Not Always Neuroinflammation!

(2014) Myka L. Estes et al.   BRAIN PATHOLOGY

Macrophagic and microglial responses after focal traumatic brain injury in the female rat

(2014) L Turtzo et al.   Journal of Neuroinflammation

Inflammation-induced DNA damage and damage-induced inflammation: a vicious cycle

(2014) Timea Pálmai-Pallag et al.   MICROBES AND INFECTION

Perspectives on neuroinflammation and excitotoxicity: A neurotoxic conspiracy?

(2014) Barbara Viviani et al.   NEUROTOXICOLOGY

The regulatory effect of veratric acid on NO production in LPS-stimulated RAW264.7 macrophage cells

(2013) Woo-Suk Choi et al.   CELLULAR IMMUNOLOGY

Acetylcholinesterase Inhibitors: Pharmacology and Toxicology

(2013) Mirjana B. Colovic et al.   Current Neuropharmacology

Oxidative damage induced by chlorpyrifos in the hepatic and renal tissue of Kunming mice and the antioxidant role of vitamin E

(2013) Ping Ma et al.   FOOD AND CHEMICAL TOXICOLOGY

Detection of the residues of nineteen pesticides in fresh vegetable samples using gas chromatography–mass spectrometry

(2013) M. Alamgir Zaman Chowdhury et al.   FOOD CONTROL

Microglia/Macrophage Polarization Dynamics in White Matter after Traumatic Brain Injury

(2013) Guohua Wang et al.   JOURNAL OF CEREBRAL BLOOD FLOW AND METABOLISM

Progressive Neurodegeneration After Experimental Brain Trauma

(2013) David J. Loane et al.   JOURNAL OF NEUROPATHOLOGY AND EXPERIMENTAL NEUROLOGY

Organophosphate pesticide levels in blood and urine of women and newborns living in an agricultural community

(2012) Karen Huen et al.   ENVIRONMENTAL RESEARCH

A review of experimental evidence linking neurotoxic organophosphorus compounds and inflammation

(2012) Christopher N. Banks et al.   NEUROTOXICOLOGY

Reactive oxygen species and the neuronal fate

(2011) Karen A. M. Kennedy et al.   CELLULAR AND MOLECULAR LIFE SCIENCES

Mechanisms of Chemical Carcinogenicity and Mutagenicity: A Review with Implications for Predictive Toxicology

(2011) Romualdo Benigni et al.   CHEMICAL REVIEWS

Infiltrating monocytes trigger EAE progression, but do not contribute to the resident microglia pool

(2011) Bahareh Ajami et al.   NATURE NEUROSCIENCE

Elevated Levels of Cell-Free Circulating DNA in Patients with Acute Dengue Virus Infection

(2011) Tran Thi Ngoc Ha et al.   PLoS One

Comparative study on modeccin- and phytohemagglutinin (PHA)-induced secretion of cytokines and nitric oxide (NO) in RAW264.7 cells

(2010) D. Kim et al.   ACTA BIOCHIMICA ET BIOPHYSICA SINICA

Resveratrol attenuates the anticancer efficacy of paclitaxel in human breast cancer cells in vitro and in vivo

(2010) Masayuki Fukui et al.   EUROPEAN JOURNAL OF CANCER

Chlorpyrifos induces oxidative stress in oligodendrocyte progenitor cells

(2009) Marilyn D. Saulsbury et al.   TOXICOLOGY