Insights into the Molecular Mechanisms of Histone Code Recognition by the BRPF3 Bromodomain

Structural Insights into the Recognition of Mono- and Diacetylated Histones by the ATAD2B Bromodomain

(2020) Jonathan T. Lloyd et al.   JOURNAL OF MEDICINAL CHEMISTRY

HBO1 is required for the maintenance of leukaemia stem cells

(2019) Laura MacPherson et al.   NATURE

Functions of bromodomain-containing proteins and their roles in homeostasis and cancer

(2017) Takao Fujisawa et al.   NATURE REVIEWS MOLECULAR CELL BIOLOGY

PDBsum: Structural summaries of PDB entries

(2017) Roman A. Laskowski et al.   PROTEIN SCIENCE

Diving into the Water: Inducible Binding Conformations for BRD4, TAF1(2), BRD9, and CECR2 Bromodomains

(2016) Terry D. Crawford et al.   JOURNAL OF MEDICINAL CHEMISTRY

ATAD2 is an epigenetic reader of newly synthesized histone marks during DNA replication

(2016) Seong Joo Koo et al.   Oncotarget

MOZ and MORF acetyltransferases: Molecular interaction, animal development and human disease

(2015) Xiang-Jiao Yang   BIOCHIMICA ET BIOPHYSICA ACTA-MOLECULAR CELL RESEARCH

BRPF3-HBO1 regulates replication origin activation and histone H3K14 acetylation

(2015) Y. Feng et al.   EMBO JOURNAL

The Chromatin Regulator BRPF3 Preferentially Activates the HBO1 Acetyltransferase but Is Dispensable for Mouse Development and Survival

(2015) Kezhi Yan et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

The Chromatin Regulator Brpf1 Regulates Embryo Development and Cell Proliferation

(2015) Linya You et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Bivalent interaction of the PZP domain of BRPF1 with the nucleosome impacts chromatin dynamics and acetylation

(2015) Brianna J. Klein et al.   NUCLEIC ACIDS RESEARCH

A Subset of Human Bromodomains Recognizes Butyryllysine and Crotonyllysine Histone Peptide Modifications

(2015) E. Megan Flynn et al.   STRUCTURE

Beating the odds: BETs in disease

(2015) Chen-Yi Wang et al.   TRENDS IN BIOCHEMICAL SCIENCES

Nucleosome Dancing at the Tempo of Histone Tail Acetylation

(2015) Angélique Galvani et al.   Genes

The bromodomain: From epigenome reader to druggable target

(2014) Roberto Sanchez et al.   Biochimica et Biophysica Acta-Gene Regulatory Mechanisms

Genome Sequencing of SHH Medulloblastoma Predicts Genotype-Related Response to Smoothened Inhibition

(2014) Marcel Kool et al.   CANCER CELL

Expression atlas of the multivalent epigenetic regulator Brpf1 and its requirement for survival of mouse embryos

(2014) Linya You et al.   Epigenetics

Structural insights into recognition of acetylated histone ligands by the BRPF1 bromodomain

(2014) Mulu Y. Lubula et al.   FEBS LETTERS

The MOZ Histone Acetyltransferase in Epigenetic Signaling and Disease

(2014) Samuel Carlson et al.   JOURNAL OF CELLULAR PHYSIOLOGY

The landscape of somatic mutations in epigenetic regulators across 1,000 paediatric cancer genomes

(2014) Robert Huether et al.   Nature Communications

Exchange of associated factors directs a switch in HBO1 acetyltransferase histone tail specificity

(2013) M.-E. Lalonde et al.   GENES & DEVELOPMENT

Molecular Insights into the Recognition of N-Terminal Histone Modifications by the BRPF1 Bromodomain

(2013) Amanda Poplawski et al.   JOURNAL OF MOLECULAR BIOLOGY

Exome sequencing identifies distinct mutational patterns in liver fluke–related and non-infection-related bile duct cancers

(2013) Waraporn Chan-on et al.   NATURE GENETICS

Histone Recognition and Large-Scale Structural Analysis of the Human Bromodomain Family

(2012) Panagis Filippakopoulos et al.   CELL

Histone methylation: a dynamic mark in health, disease and inheritance

(2012) Eric L. Greer et al.   NATURE REVIEWS GENETICS

The Hbo1-Brd1/Brpf2 complex is responsible for global acetylation of H3K14 and required for fetal liver erythropoiesis

(2011) Y. Mishima et al.   BLOOD

Definition and testing of the GROMOS force-field versions 54A7 and 54B7

(2011) Nathan Schmid et al.   EUROPEAN BIOPHYSICS JOURNAL WITH BIOPHYSICS LETTERS

Bromodomains as therapeutic targets

(2011) Susanne Muller et al.   EXPERT REVIEWS IN MOLECULAR MEDICINE

Prognosis of patients with t(8;16)(p11;p13) acute myeloid leukemia

(2011) Tanya Brown et al.   LEUKEMIA & LYMPHOMA

HBO1 Is Required for H3K14 Acetylation and Normal Transcriptional Activity during Embryonic Development

(2010) A. J. Kueh et al.   MOLECULAR AND CELLULAR BIOLOGY

HBO1 Histone Acetylase Activity Is Essential for DNA Replication Licensing and Inhibited by Geminin

(2010) Benoit Miotto et al.   MOLECULAR CELL

Support of association between BRD1 and both schizophrenia and bipolar affective disorder

(2009) Mette Nyegaard et al.   AMERICAN JOURNAL OF MEDICAL GENETICS PART B-NEUROPSYCHIATRIC GENETICS

Moz and Retinoic Acid Coordinately Regulate H3K9 Acetylation, Hox Gene Expression, and Segment Identity

(2009) Anne K. Voss et al.   DEVELOPMENTAL CELL

Histone acetyltransferase Hbo1: Catalytic activity, cellular abundance, and links to primary cancers

(2009) Masayoshi Iizuka et al.   GENE

AutoDock Vina: Improving the speed and accuracy of docking with a new scoring function, efficient optimization, and multithreading

(2009) Oleg Trott et al.   JOURNAL OF COMPUTATIONAL CHEMISTRY

HBO1 HAT Complexes Target Chromatin throughout Gene Coding Regions via Multiple PHD Finger Interactions with Histone H3 Tail

(2009) Nehmé Saksouk et al.   MOLECULAR CELL

Lysine Acetylation Targets Protein Complexes and Co-Regulates Major Cellular Functions

(2009) C. Choudhary et al.   SCIENCE

HBO1 histone acetylase is a coactivator of the replication licensing factor Cdt1

(2008) B. Miotto et al.   GENES & DEVELOPMENT

Role of Jade-1 in the Histone Acetyltransferase (HAT) HBO1 Complex

(2008) Rebecca L. Foy et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Incidence and diversity of PAX5 fusion genes in childhood acute lymphoblastic leukemia

(2008) K Nebral et al.   LEUKEMIA

Molecular Architecture of Quartet MOZ/MORF Histone Acetyltransferase Complexes

(2008) M. Ullah et al.   MOLECULAR AND CELLULAR BIOLOGY