Targeting androgen receptor (AR) with antiandrogen Enzalutamide increases prostate cancer cell invasion yet decreases bladder cancer cell invasion via differentially altering the AR/circRNA-ARC1/miR-125b-2-3p or miR-4736/PPARγ/MMP-9 signals

CRISPR Interference Efficiently Induces Specific and Reversible Gene Silencing in Human iPSCs

(2016) Mohammad A. Mandegar et al.   Cell Stem Cell

Gender and Bladder Cancer: A Collaborative Review of Etiology, Biology, and Outcomes

(2016) Jakub Dobruch et al.   EUROPEAN UROLOGY

MiR-323-5p acts as a Tumor Suppressor by Targeting the Insulin-like Growth Factor 1 Receptor in Human Glioma Cells

(2015) Hai-Wei Lian et al.   Asian Pacific Journal of Cancer Prevention

Infiltrating neutrophils promote renal cell carcinoma (RCC) proliferation via modulating androgen receptor (AR) → c-Myc signals

(2015) Wenbin Song et al.   CANCER LETTERS

Integrative Clinical Genomics of Advanced Prostate Cancer

(2015) Dan Robinson et al.   CELL

MiR-323 Inhibits Prostate Cancer Vascularization Through Adiponectin Receptor

(2015) Qiruo Gao et al.   CELLULAR PHYSIOLOGY AND BIOCHEMISTRY

Circular RNAs in the Mammalian Brain Are Highly Abundant, Conserved, and Dynamically Expressed

(2015) Agnieszka Rybak-Wolf et al.   MOLECULAR CELL

Unraveling CRISPR-Cas9 genome engineering parameters via a library-on-library approach

(2015) Raj Chari et al.   NATURE METHODS

Screening key microRNAs for castration-resistant prostate cancer based on miRNA/mRNA functional synergistic network

(2015) Jin Zhu et al.   Oncotarget

Androgen deprivation therapy prevents bladder cancer recurrence

(2015) Koji Izumi et al.   Oncotarget

The PPARγ agonist Troglitazone induces autophagy, apoptosis and necroptosis in bladder cancer cells

(2014) S Yan et al.   CANCER GENE THERAPY

ASC-J9 Suppresses Renal Cell Carcinoma Progression by Targeting an Androgen Receptor-Dependent HIF2 /VEGF Signaling Pathway

(2014) D. He et al.   CANCER RESEARCH

Good guy or bad guy: the opposing roles of microRNA 125b in cancer

(2014) Julia Banzhaf-Strathmann et al.   Cell Communication and Signaling

The combinatory effects of PPAR-γ agonist and survivin inhibition on the cancer stem-like phenotype and cell proliferation in bladder cancer cells

(2014) YANG WANG et al.   INTERNATIONAL JOURNAL OF MOLECULAR MEDICINE

Androgen deprivation–induced NCoA2 promotes metastatic and castration-resistant prostate cancer

(2014) Jun Qin et al.   JOURNAL OF CLINICAL INVESTIGATION

Therapeutic targeting of BET bromodomain proteins in castration-resistant prostate cancer

(2014) Irfan A. Asangani et al.   NATURE

The multiMiR R package and database: integration of microRNA–target interactions along with their disease and drug associations

(2014) Yuanbin Ru et al.   NUCLEIC ACIDS RESEARCH

Effects of Eicosapentaenoic Acid and Docosahexaenoic Acid on Prostate Cancer Cell Migration and Invasion Induced by Tumor-Associated Macrophages

(2014) Cheng-Chung Li et al.   PLoS One

Decreased Tumorigenesis and Mortality from Bladder Cancer in Mice Lacking Urothelial Androgen Receptor

(2013) Jong-Wei Hsu et al.   AMERICAN JOURNAL OF PATHOLOGY

Circular RNA and miR-7 in Cancer

(2013) T. B. Hansen et al.   CANCER RESEARCH

Glucocorticoid Receptor Confers Resistance to Antiandrogens by Bypassing Androgen Receptor Blockade

(2013) Vivek K. Arora et al.   CELL

RETRACTED: Construction of circular miRNA sponges targeting miR-21 or miR-221 and demonstration of their excellent anticancer effects on malignant melanoma cells

(2013) Yuchen Liu et al.   INTERNATIONAL JOURNAL OF BIOCHEMISTRY & CELL BIOLOGY

Differential Androgen Deprivation Therapies with Anti-androgens Casodex/Bicalutamide or MDV3100/EnzalutamideversusAnti-androgen Receptor ASC-J9® Lead to PromotionversusSuppression of Prostate Cancer Metastasis

(2013) Tzu-Hua Lin et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Natural RNA circles function as efficient microRNA sponges

(2013) Thomas B. Hansen et al.   NATURE

Circular RNAs are a large class of animal RNAs with regulatory potency

(2013) Sebastian Memczak et al.   NATURE

Androgen receptor (AR) differential roles in hormone-related tumors including prostate, bladder, kidney, lung, breast and liver

(2013) C Chang et al.   ONCOGENE

Epidermal growth factor enhances androgen receptor-mediated bladder cancer progression and invasion via potentiation of AR transactivation

(2013) TENG-FU HSIEH et al.   ONCOLOGY REPORTS

Anti-androgen receptor ASC-J9 versus anti-androgens MDV3100 (Enzalutamide) or Casodex (Bicalutamide) leads to opposite effects on prostate cancer metastasis via differential modulation of macrophage infiltration and STAT3-CCL2 signaling

(2013) T-H Lin et al.   Cell Death & Disease

Circular RNAs Are the Predominant Transcript Isoform from Hundreds of Human Genes in Diverse Cell Types

(2012) Julia Salzman et al.   PLoS One

Androgen Receptor Gene Expression in Prostate Cancer Is Directly Suppressed by the Androgen Receptor Through Recruitment of Lysine-Specific Demethylase 1

(2011) Changmeng Cai et al.   CANCER CELL

Transcriptome-wide discovery of circular RNAs in Archaea

(2011) Miri Danan et al.   NUCLEIC ACIDS RESEARCH

Long noncoding RNAs and human disease

(2011) Orly Wapinski et al.   TRENDS IN CELL BIOLOGY

A coding-independent function of gene and pseudogene mRNAs regulates tumour biology

(2010) Laura Poliseno et al.   NATURE

Differential androgen receptor signals in different cells explain why androgen-deprivation therapy of prostate cancer fails

(2010) Y Niu et al.   ONCOGENE

Androgen Receptor Is a New Potential Therapeutic Target for the Treatment of Hepatocellular Carcinoma

(2008) Weng–Lung Ma et al.   GASTROENTEROLOGY

Targeting the stromal androgen receptor in primary prostate tumors at earlier stages

(2008) Y. Niu et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Androgen receptor is a tumor suppressor and proliferator in prostate cancer

(2008) Y. Niu et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA