Recent studies of nitrogen containing heterocyclic compounds as novel antiviral agents: A review

Advances in the genotypic diagnosis of cytomegalovirus antiviral drug resistance

(2020) Sunwen Chou   ANTIVIRAL RESEARCH

Design, synthesis and anti-HBV activity evaluation of new substituted imidazo[4,5-b]pyridines

(2020) Maria Gerasi et al.   BIOORGANIC CHEMISTRY

Design, synthesis and structure-activity relationships of 4-phenyl-1H-1,2,3-triazole phenylalanine derivatives as novel HIV-1 capsid inhibitors with promising antiviral activities

(2020) Lin Sun et al.   EUROPEAN JOURNAL OF MEDICINAL CHEMISTRY

Transmission dynamics and evolutionary history of 2019‐nCoV

(2020) Xingguang Li et al.   JOURNAL OF MEDICAL VIROLOGY

Identification of 2-(4-(phenylsulfonyl)piperazine-1-yl)pyrimidine analogues as Novel Inhibitors of Chikungunya Virus

(2020) Julia Moesslacher et al.   ACS Medicinal Chemistry Letters

Pyrrolyl Pyrazoles as Non-Diketo Acid Inhibitors of the HIV-1 Ribonuclease H Function of Reverse Transcriptase.

(2020) Antonella Messore et al.   ACS Medicinal Chemistry Letters

Inhibition of HIV-1 RT activity by a new series of 3-(1,3,4-thiadiazol-2-yl)thiazolidin-4-one derivatives

(2020) Maria Rosa Buemi et al.   BIOORGANIC & MEDICINAL CHEMISTRY

Déjà vu: Stimulating open drug discovery for SARS-CoV-2

(2020) Sean Ekins et al.   DRUG DISCOVERY TODAY

Design, synthesis, in vitro and in silico studies of novel 4-oxoquinoline ribonucleoside derivatives as HIV-1 reverse transcriptase inhibitors

(2020) Luana da S.M. Forezi et al.   EUROPEAN JOURNAL OF MEDICINAL CHEMISTRY

Discovery of (1H-Pyrazolo[3,4-c]pyridin-5-yl)sulfonamide Analogs as Hepatitis B Virus Capsid Assembly Modulators by Conformation Constraint

(2020) Chunting Wang et al.   JOURNAL OF MEDICINAL CHEMISTRY

Synthesis, Biological Evaluation and Molecular Docking of Novel Thiophene‐Based Indole Derivatives as Potential Antibacterial, GST Inhibitor and Apoptotic Anticancer Agents

(2020) Metin Konus et al.   ChemistrySelect

Synthesis, characterization, molecular docking, and biological activities of coumarin–1,2,3‐triazole‐acetamide hybrid derivatives

(2020) Nima Sepehri et al.   ARCHIV DER PHARMAZIE

Identification of potential inhibitors of three key enzymes of SARS-CoV2 using computational approach

(2020) Hafsa Iftikhar et al.   COMPUTERS IN BIOLOGY AND MEDICINE

Straightforward synthesis of 2-chloro-N-(5-(cyanomethyl)-1,3,4-thiadiazol-2-yl)benzamide as a precursor for synthesis of novel heterocyclic compounds with insecticidal activity

(2020) Ali M. M. Mohamed et al.   SYNTHETIC COMMUNICATIONS

Advances in research of spirodienone and its derivatives: Biological activities and synthesis methods

(2020) Chen Chen et al.   EUROPEAN JOURNAL OF MEDICINAL CHEMISTRY

Discovery of HIV entry inhibitors via a hybrid CXCR4 and CCR5 receptor pharmacophore‐based virtual screening approach

(2020) Muhammad Usman Mirza et al.   EUROPEAN JOURNAL OF PHARMACEUTICAL SCIENCES

Direct-Acting Antivirals and Organ Transplantation: Is There Anything We Can’t Do?

(2020) Matthew R Kappus et al.   JOURNAL OF INFECTIOUS DISEASES

Design, synthesis, molecular docking and biological activity evaluation of some novel indole derivatives as potent anticancer active agents and apoptosis inducers

(2019) Ahmed M. Sh. El-Sharief et al.   BIOORGANIC CHEMISTRY

Piperazine-azole-fluoroquinolone hybrids: Conventional and microwave irradiated synthesis, biological activity screening and molecular docking studies

(2019) Arif Mermer et al.   BIOORGANIC CHEMISTRY

Design, synthesis and molecular docking of pyrazolo [3,4d] thiazole hybrids as potential anti-HIV-1 NNRT inhibitors

(2019) H.M. Kasralikar et al.   BIOORGANIC CHEMISTRY

Synthesis and antiviral activity of some imidazo[1,2-b][1,3,4]thiadiazole carbohydrate derivatives

(2019) Mirta L. Fascio et al.   CARBOHYDRATE RESEARCH

3-Trifluoromethylpyrazolones derived nucleosides: Synthesis and antiviral evaluation

(2019) Ayman M. S. Ahmed et al.   NUCLEOSIDES NUCLEOTIDES & NUCLEIC ACIDS

Synthesis and antiviral activity of 1-hydroxy-2-(2-hydroxyphenyl)imidazoles against vaccinia virus

(2019) P. A. Nikitina et al.   RUSSIAN CHEMICAL BULLETIN

Synthesis and biological evaluation of novel imidazole nucleosides as potential anti-dengue virus agents

(2019) Yuki Okano et al.   BIOORGANIC & MEDICINAL CHEMISTRY

Discovery of 5-(5-fluoro-1H-pyrrolo[2,3-b]pyridin-3-yl)pyrazin-2(1H)-one derivatives as new potent PB2 inhibitors

(2019) Jianhong Yang et al.   BIOORGANIC & MEDICINAL CHEMISTRY LETTERS

Examination of novel 4-aminoquinoline derivatives designed and synthesized by a hybrid pharmacophore approach to enhance their anticancer activities

(2019) V. Raja Solomon et al.   Scientific Reports

Design, Synthesis, and Biological Evaluation of Substituted 4,6-Dihydrospiro[[1,2,3]triazolo[4,5-b]pyridine-7,3′-indoline]-2′,5(3H)-dione Analogues as Potent NS4B Inhibitors for the Treatment of Dengue Virus Infection

(2019) Jimin Xu et al.   JOURNAL OF MEDICINAL CHEMISTRY

Indazolyl-substituted piperidin-4-yl-aminopyrimidines as HIV-1 NNRTIs: Design, synthesis and biological activities

(2019) Ting Xiao et al.   EUROPEAN JOURNAL OF MEDICINAL CHEMISTRY

Facile and expedient synthesis and anti-proliferative activity of diversely pyrrolones bearing 1,3-diphenylpyrazole moiety

(2019) Sayed K. Ramadan et al.   SYNTHETIC COMMUNICATIONS

Superior inhibition of influenza virus hemagglutinin-mediated fusion by indole-substituted spirothiazolidinones

(2019) Gökçe Cihan-Üstündağ et al.   BIOORGANIC & MEDICINAL CHEMISTRY

Discovery of a novel unsymmetrical structural class of HCV NS5A inhibitors with low picomolar antiviral activity

(2019) Hiroshi Nakamura et al.   BIOORGANIC & MEDICINAL CHEMISTRY LETTERS

Design and synthesis of novel Imidazo[2,1-b]thiazole derivatives as potent antiviral and antimycobacterial agents

(2019) Elif Gürsoy et al.   BIOORGANIC CHEMISTRY

Antitumor and antiviral activities of 4-substituted 1,2,3-triazolyl-2,3-dibenzyl-L-ascorbic acid derivatives

(2019) Andrijana Meščić Macan et al.   EUROPEAN JOURNAL OF MEDICINAL CHEMISTRY

Preliminary SAR and biological evaluation of potent HIV-1 protease inhibitors with pyrimidine bases as novel P2 ligands to enhance activity against DRV-resistant HIV-1 variants

(2019) Mei Zhu et al.   EUROPEAN JOURNAL OF MEDICINAL CHEMISTRY

Synthesis and in–vitro anti–HIV–1 evaluation of novel pyrazolo[4,3–c]pyridin–4–one derivatives

(2019) Sanjay Kumar et al.   EUROPEAN JOURNAL OF MEDICINAL CHEMISTRY

Innovation and trends in the development and approval of antiviral medicines: 1987–2017 and beyond

(2018) Shuvam Chaudhuri et al.   ANTIVIRAL RESEARCH

Conventional and microwave prompted synthesis, antioxidant, anticholinesterase activity screening and molecular docking studies of new quinolone-triazole hybrids

(2018) Arif Mermer et al.   BIOORGANIC CHEMISTRY

In vitro evaluation of current and novel antivirals in combination against human cytomegalovirus

(2018) M. Shea O’Brien et al.   ANTIVIRAL RESEARCH

Some pyrazoles derivatives: Potent carbonic anhydrase, α-glycosidase, and cholinesterase enzymes inhibitors

(2018) Fikret Turkan et al.   ARCHIV DER PHARMAZIE

Synthesis, biological activity and structure activity relationship studies of novel conazole analogues via conventional, microwave and ultrasound mediated techniques

(2018) Arif Mermer et al.   BIOORGANIC CHEMISTRY

Structure-Based Drug Design of Potent Pyrazole Derivatives against Rhinovirus Replication

(2018) Laurène Da Costa et al.   JOURNAL OF MEDICINAL CHEMISTRY

Synthesis and antiviral activity of camphor-based 1,3-thiazolidin-4-one and thiazole derivatives as Orthopoxvirus-reproduction inhibitors

(2018) Anastasiya S. Sokolova et al.   MedChemComm

Antiviral activities of Janus-type nucleosides and their related oxime-intermediates

(2018) Jiang Liu et al.   BIOORGANIC & MEDICINAL CHEMISTRY

Design and synthesis of a novel series of non-nucleoside HIV-1 inhibitors bearing pyrimidine and N-substituted aromatic piperazine

(2018) KaiJun Jin et al.   BIOORGANIC & MEDICINAL CHEMISTRY LETTERS

A Survey of the Structures of US FDA Approved Combination Drugs

(2018) Pradipta Das et al.   JOURNAL OF MEDICINAL CHEMISTRY

NS5A inhibitors for the treatment of hepatitis C infection

(2017) Stefano Gitto et al.   JOURNAL OF VIRAL HEPATITIS

Design, Synthesis, and Evaluation of Tetrahydropyrrolo[1,2-c]pyrimidines as Capsid Assembly Inhibitors for HBV Treatment

(2017) Xiaolin Li et al.   ACS Medicinal Chemistry Letters

Design, synthesis and antiviral evaluation of novel heteroarylcarbothioamide derivatives as dual inhibitors of HIV-1 reverse transcriptase-associated RNase H and RDDP functions

(2017) Angela Corona et al.   Pathogens and Disease

Design, synthesis, and in vitro biological evaluation of novel 6-methyl-7-substituted-7-deaza purine nucleoside analogs as anti-influenza A agents

(2016) Cai Lin et al.   ANTIVIRAL RESEARCH

Discovery of conjugated thiazolidinone-thiadiazole scaffold as anti-dengue virus polymerase inhibitors

(2016) Dinesh Manvar et al.   BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS

Novel indole sulfides as potent HIV-1 NNRTIs

(2016) Siobhan Brigg et al.   BIOORGANIC & MEDICINAL CHEMISTRY LETTERS

Synthetic strategy and antiviral evaluation of diamide containing heterocycles targeting dengue and yellow fever virus

(2016) Milind Saudi et al.   EUROPEAN JOURNAL OF MEDICINAL CHEMISTRY

Direct-acting antivirals for the treatment of hepatitis C virus infection: optimizing current IFN-free treatment and future perspectives

(2016) Tarik Asselah et al.   LIVER INTERNATIONAL

Novel 5-alkyl(aryl)-substituted ribavirine analogues: synthesis and antiviral evaluation

(2016) Mikhail V. Chudinov et al.   MENDELEEV COMMUNICATIONS

Design and synthesis of pyridine-pyrazole-sulfonate derivatives as potential anti-HBV agents

(2016) Hong Chuang et al.   MedChemComm

Entry inhibitors: New advances in HCV treatment

(2016) Xi-Jing Qian et al.   Emerging Microbes & Infections

Discovery of the 2-phenyl-4,5,6,7-Tetrahydro-1H-indole as a novel anti-hepatitis C virus targeting scaffold

(2015) Ivan A. Andreev et al.   EUROPEAN JOURNAL OF MEDICINAL CHEMISTRY

Recent advances in bioactive pyrazoles

(2015) Ş.Güniz Küçükgüzel et al.   EUROPEAN JOURNAL OF MEDICINAL CHEMISTRY

5′-Silylated 3′-1,2,3-triazolyl Thymidine Analogues as Inhibitors of West Nile Virus and Dengue Virus

(2015) Sanjeev Kumar V. Vernekar et al.   JOURNAL OF MEDICINAL CHEMISTRY

Structure–Activity Relationship of Pyrrolyl Diketo Acid Derivatives as Dual Inhibitors of HIV-1 Integrase and Reverse Transcriptase Ribonuclease H Domain

(2015) Giuliana Cuzzucoli Crucitti et al.   JOURNAL OF MEDICINAL CHEMISTRY

Coumarin hybrids as novel therapeutic agents

(2014) Sonali Sandhu et al.   BIOORGANIC & MEDICINAL CHEMISTRY

Synthesis, antioxidant and DNA cleavage activities of novel indole derivatives

(2010) J.S. Biradar et al.   EUROPEAN JOURNAL OF MEDICINAL CHEMISTRY

Antioxidant activity of 5,10-dihydroindeno[1,2-b]indoles containing substituents on dihydroindeno part

(2009) Oktay Talaz et al.   BIOORGANIC & MEDICINAL CHEMISTRY