标题
The role of Hypoxia-Inducible Factor-1alpha and its signaling in melanoma
作者
关键词
Hypoxia, HIF-1α, Melanoma, Signaling pathways, Diagnostic/prognostic biomarker, Melanoma treatment
出版物
BIOMEDICINE & PHARMACOTHERAPY
Volume 141, Issue -, Pages 111873
出版商
Elsevier BV
发表日期
2021-07-02
DOI
10.1016/j.biopha.2021.111873
参考文献
相关参考文献
注意：仅列出部分参考文献，下载原文获取全部文献信息。- Long noncoding RNA LINC00518 induces radioresistance by regulating glycolysis through an miR-33a-3p/HIF-1α negative feedback loop in melanoma
- (2021) Yan Liu et al. Cell Death & Disease
- Morphological Characteristic of Melanoma B16 Progression in C57BL/6 Mice with High and Low Resistance to Hypoxia
- (2020) I. A. Fridman et al. BULLETIN OF EXPERIMENTAL BIOLOGY AND MEDICINE
- Metabolic Reprogramming in Metastatic Melanoma with Acquired Resistance to Targeted Therapies: Integrative Metabolomic and Proteomic Analysis
- (2020) Laura Soumoy et al. Cancers
- Implications of HIF-1α in the tumorigenesis and progression of pancreatic cancer
- (2020) Xiao Jin et al. Cancer Cell International
- Acriflavine, a Potent Inhibitor of HIF-1α, Disturbs Glucose Metabolism and Suppresses ATF4-Protective Pathways in Melanoma under Non-Hypoxic Conditions
- (2020) Román Martí-Díaz et al. Cancers
- HIF-1α/VEGF signaling-mediated epithelial-mesenchymal transition and angiogenesis is critically involved in anti-metastasis effect of luteolin in melanoma cells
- (2019) Chunyu Li et al. PHYTOTHERAPY RESEARCH
- HIF1α Suppresses Tumor Cell Proliferation through Inhibition of Aspartate Biosynthesis
- (2019) Florinda Meléndez-Rodríguez et al. Cell Reports
- Knockdown of FBXO22 inhibits melanoma cell migration, invasion and angiogenesis via the HIF-1α/VEGF pathway
- (2019) Yufan Zheng et al. INVESTIGATIONAL NEW DRUGS
- The inhibition of hypoxia-induced angiogenesis and metastasis by cinnamaldehyde is mediated by decreasing HIF-1α protein synthesis via PI3K/Akt pathway
- (2019) Kartick Patra et al. BIOFACTORS
- Search for novel STAT3-dependent genes reveals SERPINA3 as a new STAT3 target that regulates invasion of human melanoma cells
- (2019) Dorota W. Kulesza et al. LABORATORY INVESTIGATION
- MicroRNA-138 negatively regulates the hypoxia-inducible factor 1α to suppress melanoma growth and metastasis
- (2019) Haijiang Qiu et al. Biology Open
- Characterization of glycolysis-related gene expression in malignant melanoma
- (2019) Andreas Koch et al. PATHOLOGY RESEARCH AND PRACTICE
- miR-652 Promotes Proliferation and Migration of Uveal Melanoma Cells by Targeting HOXA9
- (2019) Zhaoxia Xia et al. MEDICAL SCIENCE MONITOR
- Regulatory mechanisms of hypoxia-inducible factor 1 activity: Two decades of knowledge
- (2018) Sho Koyasu et al. CANCER SCIENCE
- Positive and Negative Regulation of Angiogenesis by Soluble Vascular Endothelial Growth Factor Receptor-1
- (2018) Cristina Failla et al. INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES
- Implications of STAT3 and STAT5 signaling on gene regulation and chromatin remodeling in hematopoietic cancer
- (2018) Bettina Wingelhofer et al. LEUKEMIA
- Combination of anti-vascular agent - DMXAA and HIF-1α inhibitor - digoxin inhibits the growth of melanoma tumors
- (2018) Ryszard Smolarczyk et al. Scientific Reports
- Melanoma response to anti-PD-L1 immunotherapy requires JAK1 signaling, but not JAK2
- (2018) Na Luo et al. OncoImmunology
- PTEN: Tumor Suppressor and Metabolic Regulator
- (2018) Chien-Yu Chen et al. Frontiers in Endocrinology
- Hypoxia-Inducible Factor-1α Activity as a Switch for Glioblastoma Responsiveness to Temozolomide
- (2018) Alessia Lo Dico et al. Frontiers in Oncology
- Systematic Review and Meta-analysis of the Prognostic Significance of miRNAs in Melanoma Patients
- (2018) Shanthi Sabarimurugan et al. Molecular Diagnosis & Therapy
- Arylsulfonamide 64B inhibits hypoxia/HIF-induced expression of c-Met and CXCR4 and reduces primary tumor growth and metastasis of uveal melanoma
- (2018) Erwin G. Van Meir et al. CLINICAL CANCER RESEARCH
- Role of miRNA-210, miRNA-21 and miRNA-126 as diagnostic biomarkers in colorectal carcinoma: impact of HIF-1α-VEGF signaling pathway
- (2018) Dina Sabry et al. MOLECULAR AND CELLULAR BIOCHEMISTRY
- Effects of proton pump inhibitors on reversing multidrug resistance via downregulating V-ATPases/PI3K/Akt/mTOR/HIF-1α signaling pathway through TSC1/2 complex and Rheb in human gastric adenocarcinoma cells in vitro and in vivo
- (2018) Min Chen et al. OncoTargets and Therapy
- uPA/uPAR system activation drives a glycolytic phenotype in melanoma cells
- (2017) Anna Laurenzana et al. INTERNATIONAL JOURNAL OF CANCER
- Vanillin Suppresses Cell Motility by Inhibiting STAT3-Mediated HIF-1α mRNA Expression in Malignant Melanoma Cells
- (2017) Eun-Ji Park et al. INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES
- 2-Methoxyestradiol enhances radiosensitivity in radioresistant melanoma MDA-MB-435R cells by regulating glycolysis via HIF-1α/PDK1 axis
- (2017) Hong Zhao et al. INTERNATIONAL JOURNAL OF ONCOLOGY
- Hypoxia and Hyperoxia Affect Serum Angiogenic Regulators in T2DM Men during Cycling
- (2017) Christian Brinkmann et al. INTERNATIONAL JOURNAL OF SPORTS MEDICINE
- MicroRNA-Directed Cancer Therapies: Implications in Melanoma Intervention
- (2017) Anita Thyagarajan et al. JOURNAL OF PHARMACOLOGY AND EXPERIMENTAL THERAPEUTICS
- A prospective multicenter cohort study of cutaneous melanoma
- (2017) Miguel Ángel Martínez-García et al. MELANOMA RESEARCH
- MicroRNA-33b inhibits cell proliferation and glycolysis by targeting hypoxia-inducible factor-1α in malignant melanoma
- (2017) Yue Zhao et al. Experimental and Therapeutic Medicine
- HIF-1α acts as a molecular target for simvastatin cytotoxicity in B16.F10 melanoma cells cultured under chemically induced hypoxia
- (2017) Emilia Licarete et al. Oncology Letters
- microRNA-33a-5p increases radiosensitivity by inhibiting glycolysis in melanoma
- (2017) Ke Cao et al. Oncotarget
- Accelerated tumor growth under intermittent hypoxia is associated with hypoxia-inducible factor-1-dependent adaptive responses to hypoxia
- (2017) Dae Wui Yoon et al. Oncotarget
- Overexpression of hypoxia-inducible factor and metabolic pathways: possible targets of cancer
- (2017) Davinder Singh et al. Cell and Bioscience
- MicroRNAs as potential diagnostic and prognostic biomarkers in melanoma
- (2016) Hamed Mirzaei et al. EUROPEAN JOURNAL OF CANCER
- Hypoxia, Hypoxia-inducible Transcription Factors, and Renal Cancer
- (2016) Johannes Schödel et al. EUROPEAN UROLOGY
- Hyperthermia induced HIF-1a expression of lung cancer through AKT and ERK signaling pathways
- (2016) Jun Wan et al. JOURNAL OF EXPERIMENTAL & CLINICAL CANCER RESEARCH
- MicroRNA 211 Functions as a Metabolic Switch in Human Melanoma Cells
- (2016) Joseph Mazar et al. MOLECULAR AND CELLULAR BIOLOGY
- MicroRNA-199a-5p inhibits tumor proliferation in melanoma by mediating HIF-1α
- (2016) XINGHUA YANG et al. Molecular Medicine Reports
- MicroRNA-18b inhibits the growth of malignant melanoma via inhibition of HIF-1α-mediated glycolysis
- (2016) YAO CHEN et al. ONCOLOGY REPORTS
- MicroRNA-138 suppresses proliferation, invasion and glycolysis in malignant melanoma cells by targeting HIF-1α
- (2016) YAO CHEN et al. Experimental and Therapeutic Medicine
- Combining clinicopathological predictors and molecular biomarkers in the oncogenic K-RAS/Ki67/HIF-1α pathway to predict survival in resectable pancreatic cancer
- (2015) R Qin et al. BRITISH JOURNAL OF CANCER
- miR-33a functions as a tumor suppressor in melanoma by targeting HIF-1α
- (2015) Jianda Zhou et al. CANCER BIOLOGY & THERAPY
- Hypoxia and hypoxia inducible factors in tumor metabolism
- (2015) Wen Zeng et al. CANCER LETTERS
- Hypoxia-inducible factor 1 and breast cancer metastasis
- (2015) Zhao-ji Liu et al. Journal of Zhejiang University-SCIENCE B
- Cancer metabolism and the Warburg effect: the role of HIF-1 and PI3K
- (2015) Rupert Courtnay et al. MOLECULAR BIOLOGY REPORTS
- Hypoxia-inducible factor-1α and Wnt/β-catenin signaling pathways promote the invasion of hypoxic gastric cancer cells
- (2015) HONG-LAN LIU et al. Molecular Medicine Reports
- MITF drives endolysosomal biogenesis and potentiates Wnt signaling in melanoma cells
- (2015) Diego Ploper et al. PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA
- Direct role of nucleotide metabolism in C-MYC-dependent proliferation of melanoma cells
- (2014) Sudha Mannava et al. CELL CYCLE
- MicroRNA-155 deficiency enhances the recruitment and functions of myeloid-derived suppressor cells in tumor microenvironment and promotes solid tumor growth
- (2014) Junfeng Wang et al. INTERNATIONAL JOURNAL OF CANCER
- Inhibition of MAPKs, Myc/Max, NFκB, and Hypoxia Pathways by Phyllanthus Prevents Proliferation, Metastasis and Angiogenesis in Human Melanoma (MeWo) Cancer Cell Line
- (2014) Yin-Quan Tang et al. International Journal of Medical Sciences
- Making new contacts: the mTOR network in metabolism and signalling crosstalk
- (2014) Mitsugu Shimobayashi et al. NATURE REVIEWS MOLECULAR CELL BIOLOGY
- Distinct microRNA expression signatures are associated with melanoma subtypes and are regulated by HIF1A
- (2014) Hun-Way Hwang et al. Pigment Cell & Melanoma Research
- Targeting RAS/RAF/MEK/ERK signaling in metastatic melanoma
- (2013) Ao-Xue Wang et al. IUBMB LIFE
- c-Myc enhances colon cancer cell-mediated angiogenesis through the regulation of HIF-1α
- (2012) Cheng Chen et al. BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS
- Inactivation of the HIF-1 /PDK3 Signaling Axis Drives Melanoma toward Mitochondrial Oxidative Metabolism and Potentiates the Therapeutic Activity of Pro-Oxidants
- (2012) J. Kluza et al. CANCER RESEARCH
- Glucose transporters in cancer metabolism
- (2012) Kehinde Adekola et al. CURRENT OPINION IN ONCOLOGY
- Sensitivity to the MEK inhibitor E6201 in melanoma cells is associated with mutant BRAF and wildtype PTEN status
- (2012) Sara A Byron et al. Molecular Cancer
- Microvessel density and VEGF, HIF-1α expression in primary oral melanoma: correlation with prognosis
- (2012) O Simonetti et al. ORAL DISEASES
- Mitochondrial Respiration - An Important Therapeutic Target in Melanoma
- (2012) Michelle Barbi de Moura et al. PLoS One
- Comparative Metabolic Flux Profiling of Melanoma Cell Lines
- (2011) David A. Scott et al. JOURNAL OF BIOLOGICAL CHEMISTRY
- E-cadherin inhibits tumor cell growth by suppressing PI3K/Akt signaling via β-catenin-Egr1-mediated PTEN expression
- (2011) M-T Lau et al. ONCOGENE
- RG7204 (PLX4032), a Selective BRAFV600E Inhibitor, Displays Potent Antitumor Activity in Preclinical Melanoma Models
- (2010) H. Yang et al. CANCER RESEARCH
- MicroRNA-519c Suppresses Hypoxia-Inducible Factor-1α Expression and Tumor Angiogenesis
- (2010) Shih-Ting Cha et al. CANCER RESEARCH
- Hypoxia and Hypoxia-Inducible Factors: Master Regulators of Metastasis
- (2010) X. Lu et al. CLINICAL CANCER RESEARCH
- Interleukin-29 Binds to Melanoma Cells Inducing Jak-STAT Signal Transduction and Apoptosis
- (2010) K. D. Guenterberg et al. MOLECULAR CANCER THERAPEUTICS
- Activated STAT3 Regulates Hypoxia-Induced Angiogenesis and Cell Migration in Human Glioblastoma
- (2010) Shin-Hyuk Kang et al. NEUROSURGERY
- Hypoxia and RAS-signaling pathways converge on and cooperatively downregulate, the RECK tumor-suppressor protein through microRNAs
- (2010) F Loayza-Puch et al. ONCOGENE
- A Re-evaluation of the “Oncogenic” Nature of Wnt/β-catenin Signaling in Melanoma and Other Cancers
- (2010) Olivia M. Lucero et al. Current Oncology Reports
- Targeting angiogenesis in melanoma: prospects for the future
- (2010) P.G. Corrie et al. Therapeutic Advances in Medical Oncology
- Prognostic relevance of hypoxia inducible factor-1α expression in patients with melanoma
- (2009) J. Valencak et al. CLINICAL AND EXPERIMENTAL DERMATOLOGY
- HIF-1: upstream and downstream of cancer metabolism
- (2009) Gregg L Semenza CURRENT OPINION IN GENETICS & DEVELOPMENT
- The Cooperative Induction of Hypoxia-Inducible Factor-1 and STAT3 during Hypoxia Induced an Impairment of Tumor Susceptibility to CTL-Mediated Cell Lysis
- (2009) M. Z. Noman et al. JOURNAL OF IMMUNOLOGY
- EGF-Induced ERK Activation Promotes CK2-Mediated Disassociation of α-Catenin from β-Catenin and Transactivation of β-Catenin
- (2009) Haitao Ji et al. MOLECULAR CELL
- Inhibition of Siah2 ubiquitin ligase by vitamin K3 (menadione) attenuates hypoxia and MAPK signaling and blocks melanoma tumorigenesis
- (2009) Meera Shah et al. Pigment Cell & Melanoma Research
- Targeting Hypoxia-inducible Factor-1α With Tf–PEI–shRNA Complex via Transferrin Receptor–mediated Endocytosis Inhibits Melanoma Growth
- (2008) Yeqiang Liu et al. MOLECULAR THERAPY
- Direct regulation of TWIST by HIF-1α promotes metastasis
- (2008) Muh-Hwa Yang et al. NATURE CELL BIOLOGY
- Understanding Signaling Cascades in Melanoma
- (2008) Pablo Lopez-Bergami et al. PHOTOCHEMISTRY AND PHOTOBIOLOGY
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