PFKFB3 gene deletion in endothelial cells inhibits intraplaque angiogenesis and lesion formation in a murine model of venous bypass grafting

Atorvastatin pleiotropically decreases intraplaque angiogenesis and intraplaque haemorrhage by inhibiting ANGPT2 release and VE-Cadherin internalization

(2021) Fabiana Baganha et al.   ANGIOGENESIS

Prolonged Hyperoxygenation Treatment Improves Vein Graft Patency and Decreases Macrophage Content in Atherosclerotic Lesions in ApoE3*Leiden Mice

(2020) Laura Parma et al.   Cells

Partial Inhibition of Glycolysis Reduces Atherogenesis Independent of Intraplaque Neovascularization in Mice

(2020) Paola Perrotta et al.   ARTERIOSCLEROSIS THROMBOSIS AND VASCULAR BIOLOGY

Atherogenic Lipoprotein(a) Increases Vascular Glycolysis, Thereby Facilitating Inflammation and Leukocyte Extravasation

(2020) Johan G. Schnitzler et al.   CIRCULATION RESEARCH

N-terminal syndecan-2 domain selectively enhances 6-O heparan sulfate chains sulfation and promotes VEGFA165-dependent neovascularization

(2019) Federico Corti et al.   Nature Communications

Partial Inhibition Of The Key Glycolytic Enzyme Pfkfb3 In Myeloid Cells Impacts Whole-Body Immune Cell And Liver Metabolism, But Not Atherogenesis.

(2019) J. De Bruijn et al.   ATHEROSCLEROSIS

Consensus guidelines for the use and interpretation of angiogenesis assays

(2018) Patrycja Nowak-Sliwinska et al.   ANGIOGENESIS

Endothelial Cell Metabolism

(2018) Guy Eelen et al.   PHYSIOLOGICAL REVIEWS

Graft failure and recurrence of symptoms after coronary artery bypass grafting

(2018) Mikael Janiec et al.   SCANDINAVIAN CARDIOVASCULAR JOURNAL

Blockade of vascular endothelial growth factor receptor 2 inhibits intraplaque haemorrhage by normalization of plaque neovessels

(2018) M. R. de Vries et al.   JOURNAL OF INTERNAL MEDICINE

Endothelial-Specific Cre Mouse Models

(2018) Sophie Payne et al.   ARTERIOSCLEROSIS THROMBOSIS AND VASCULAR BIOLOGY

Plaque angiogenesis and intraplaque hemorrhage in atherosclerosis

(2017) Laura Parma et al.   EUROPEAN JOURNAL OF PHARMACOLOGY

Interaction of endothelial cells with macrophages—linking molecular and metabolic signaling

(2017) Joanna Kalucka et al.   PFLUGERS ARCHIV-EUROPEAN JOURNAL OF PHYSIOLOGY

Hypoxia-Inducible Factor-1α Expression in Macrophages Promotes Development of AtherosclerosisHighlights

(2016) Annemarie Aarup et al.   ARTERIOSCLEROSIS THROMBOSIS AND VASCULAR BIOLOGY

Inhibition of the Glycolytic Activator PFKFB3 in Endothelium Induces Tumor Vessel Normalization, Impairs Metastasis, and Improves Chemotherapy

(2016) Anna Rita Cantelmo et al.   CANCER CELL

Macrophage Metabolism Controls Tumor Blood Vessel Morphogenesis and Metastasis

(2016) Mathias Wenes et al.   Cell Metabolism

Plaque angiogenesis and its relation to inflammation and atherosclerotic plaque destabilization

(2016) Margreet R. de Vries et al.   CURRENT OPINION IN LIPIDOLOGY

Vein graft failure: from pathophysiology to clinical outcomes

(2016) Margreet R. de Vries et al.   Nature Reviews Cardiology

HIF-1  and PFKFB3 Mediate a Tight Relationship Between Proinflammatory Activation and Anerobic Metabolism in Atherosclerotic Macrophages

(2015) A. Tawakol et al.   ARTERIOSCLEROSIS THROMBOSIS AND VASCULAR BIOLOGY

Endothelial Metabolism Driving Angiogenesis

(2015) Anna Rita Cantelmo et al.   CANCER JOURNAL

Pathophysiology of native coronary, vein graft and in-stent atherosclerosis

(2015) Kazuyuki Yahagi et al.   Nature Reviews Cardiology

Endothelial miR-17∼92 cluster negatively regulates arteriogenesis via miRNA-19 repression of WNT signaling

(2015) Shira Landskroner-Eiger et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Novel Markers to Delineate Murine M1 and M2 Macrophages

(2015) Kyle A. Jablonski et al.   PLoS One

Role of PFKFB3-Driven Glycolysis in Vessel Sprouting

(2013) Katrien De Bock et al.   CELL

Partial and Transient Reduction of Glycolysis by PFKFB3 Blockade Reduces Pathological Angiogenesis

(2013) Sandra Schoors et al.   Cell Metabolism

Reciprocal interactions between endothelial cells and macrophages in angiogenic vascular niches

(2013) Caroline Baer et al.   EXPERIMENTAL CELL RESEARCH

Plaque Rupture Complications in Murine Atherosclerotic Vein Grafts Can Be Prevented by TIMP-1 Overexpression

(2012) Margreet R. de Vries et al.   PLoS One

Ephrin-B2 controls VEGF-induced angiogenesis and lymphangiogenesis

(2010) Yingdi Wang et al.   NATURE