Interaction of endothelial cells with macrophages—linking molecular and metabolic signaling

The impact of impaired macrophage functions in cystic fibrosis disease progression

(2017) Manuella Lévêque et al.   Journal of Cystic Fibrosis

Inhibition of the Glycolytic Activator PFKFB3 in Endothelium Induces Tumor Vessel Normalization, Impairs Metastasis, and Improves Chemotherapy

(2016) Anna Rita Cantelmo et al.   CANCER CELL

Succinate Dehydrogenase Supports Metabolic Repurposing of Mitochondria to Drive Inflammatory Macrophages

(2016) Evanna L. Mills et al.   CELL

Macrophage Metabolism Controls Tumor Blood Vessel Morphogenesis and Metastasis

(2016) Mathias Wenes et al.   Cell Metabolism

Recent insights into endothelial control of leukocyte extravasation

(2016) Peter L. Hordijk   CELLULAR AND MOLECULAR LIFE SCIENCES

Endothelial Cell Dysfunction and the Pathobiology of Atherosclerosis

(2016) Michael A. Gimbrone et al.   CIRCULATION RESEARCH

Mitochondrial Dysfunction Prevents Repolarization of Inflammatory Macrophages

(2016) Jan Van den Bossche et al.   Cell Reports

Macrophages and Their Role in Atherosclerosis: Pathophysiology and Transcriptome Analysis

(2016) Yuri V. Bobryshev et al.   Biomed Research International

Mercury Exposure and Endothelial Dysfunction

(2015) Swati Omanwar et al.   INTERNATIONAL JOURNAL OF TOXICOLOGY

Regulation of atherosclerotic plaque inflammation

(2015) M. Bäck et al.   JOURNAL OF INTERNAL MEDICINE

Understanding the Mysterious M2 Macrophage through Activation Markers and Effector Mechanisms

(2015) Tamás Rőszer   MEDIATORS OF INFLAMMATION

Proteomics-Based Metabolic Modeling Reveals That Fatty Acid Oxidation (FAO) Controls Endothelial Cell (EC) Permeability

(2015) Francesca Patella et al.   MOLECULAR & CELLULAR PROTEOMICS

Fatty acid carbon is essential for dNTP synthesis in endothelial cells

(2015) Sandra Schoors et al.   NATURE

Macrophages are recruited to hypoxic tumor areas and acquire a Pro-Angiogenic M2-Polarized phenotype via hypoxic cancer cell derived cytokines Oncostatin M and Eotaxin

(2015) Chakrapani Tripathi et al.   Oncotarget

The endothelial glycocalyx: a review of the vascular barrier

(2014) C. S. Alphonsus et al.   ANAESTHESIA

Monocytes Are Recruited From Venules During Arteriogenesis in the Murine Spinotrapezius Ligation Model

(2014) Anthony C. Bruce et al.   ARTERIOSCLEROSIS THROMBOSIS AND VASCULAR BIOLOGY

Endothelial PFKFB3 Plays a Critical Role in Angiogenesis

(2014) Yiming Xu et al.   ARTERIOSCLEROSIS THROMBOSIS AND VASCULAR BIOLOGY

CCL2-dependent infiltrating macrophages promote angiogenesis in progressive liver fibrosis

(2014) Josef Ehling et al.   GUT

Metabolism of stromal and immune cells in health and disease

(2014) Bart Ghesquière et al.   NATURE

Functional polarization of tumour-associated macrophages by tumour-derived lactic acid

(2014) Oscar R. Colegio et al.   NATURE

The cellular and molecular origin of tumor-associated macrophages

(2014) R. A. Franklin et al.   SCIENCE

Role of tumor associated macrophages in tumor angiogenesis and lymphangiogenesis

(2014) Vladimir Riabov et al.   Frontiers in Physiology

Impeding Macrophage Entry into Hypoxic Tumor Areas by Sema3A/Nrp1 Signaling Blockade Inhibits Angiogenesis and Restores Antitumor Immunity

(2013) Andrea Casazza et al.   CANCER CELL

Role of PFKFB3-Driven Glycolysis in Vessel Sprouting

(2013) Katrien De Bock et al.   CELL

Impaired Cholesterol Efflux in Senescent Macrophages Promotes Age-Related Macular Degeneration

(2013) Abdoulaye Sene et al.   Cell Metabolism

Role of Endothelial Cell Metabolism in Vessel Sprouting

(2013) Katrien De Bock et al.   Cell Metabolism

Partial and Transient Reduction of Glycolysis by PFKFB3 Blockade Reduces Pathological Angiogenesis

(2013) Sandra Schoors et al.   Cell Metabolism

Role of the Endothelial-Derived Endogenous Anti-Inflammatory Factor Del-1 in Inflammation-Mediated Adrenal Gland Dysfunction

(2013) Waldemar Kanczkowski et al.   ENDOCRINOLOGY

Reciprocal interactions between endothelial cells and macrophages in angiogenic vascular niches

(2013) Caroline Baer et al.   EXPERIMENTAL CELL RESEARCH

Loss of prolyl hydroxylase-2 in myeloid cells and T-lymphocytes impairs tumor development

(2013) Soulafa Mamlouk et al.   INTERNATIONAL JOURNAL OF CANCER

Lactate Engages Receptor Tyrosine Kinases Axl, Tie2, and Vascular Endothelial Growth Factor Receptor 2 to Activate Phosphoinositide 3-Kinase/Akt and Promote Angiogenesis

(2013) Guo-Xiang Ruan et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Succinate is an inflammatory signal that induces IL-1β through HIF-1α

(2013) G. M. Tannahill et al.   NATURE

Getting Leukocytes to the Site of Inflammation

(2013) W. A. Muller   VETERINARY PATHOLOGY

Relevance of endothelial junctions in leukocyte extravasation and vascular permeability

(2012) Dietmar Vestweber   Annals of the New York Academy of Sciences

CCR2 recruits an inflammatory macrophage subpopulation critical for angiogenesis in tissue repair

(2012) S. Willenborg et al.   BLOOD

Endothelial cells provide an instructive niche for the differentiation and functional polarization of M2-like macrophages

(2012) H. He et al.   BLOOD

Orchestration of Metabolism by Macrophages

(2012) Subhra K. Biswas et al.   Cell Metabolism

Impaired Vasodilation in the Pathogenesis of Hypertension: Focus on Nitric Oxide, Endothelial-Derived Hyperpolarizing Factors, and Prostaglandins

(2012) Thomas D. Giles et al.   Journal of Clinical Hypertension

Hyperlipidemia as a Risk Factor for Cardiovascular Disease

(2012) Robert H. Nelson   PRIMARY CARE

Chemokines, selectins and intracellular calcium flux: temporal and spatial cues for leukocyte arrest

(2012) Neha Dixit et al.   Frontiers in Immunology

Basic and Therapeutic Aspects of Angiogenesis

(2011) Michael Potente et al.   CELL

Molecular mechanisms and clinical applications of angiogenesis

(2011) Peter Carmeliet et al.   NATURE

Role of cellular mechanics in the function and life span of vascular endothelium

(2011) Katrin Kliche et al.   PFLUGERS ARCHIV-EUROPEAN JOURNAL OF PHYSIOLOGY

Role of the endothelium in inflammatory bowel diseases

(2011) Walter E Cromer   WORLD JOURNAL OF GASTROENTEROLOGY

Vascular Cell Adhesion Molecule-1 Expression and Signaling During Disease: Regulation by Reactive Oxygen Species and Antioxidants

(2010) Joan M. Cook-Mills et al.   ANTIOXIDANTS & REDOX SIGNALING

Tissue macrophages act as cellular chaperones for vascular anastomosis downstream of VEGF-mediated endothelial tip cell induction

(2010) A. Fantin et al.   BLOOD

Macrophage Diversity Enhances Tumor Progression and Metastasis

(2010) Bin-Zhi Qian et al.   CELL

Angiogenesis in inflammatory bowel disease

(2010) I. D. Pousa et al.   EUROPEAN JOURNAL OF CLINICAL INVESTIGATION

Differential Roles of Macrophages in Diverse Phases of Skin Repair

(2010) T. Lucas et al.   JOURNAL OF IMMUNOLOGY

Blood Monocytes: Development, Heterogeneity, and Relationship with Dendritic Cells

(2009) Cedric Auffray et al.   Annual Review of Immunology

ICAM-1/LFA-1 interaction contributes to the induction of endothelial cell-cell separation: implication for enhanced leukocyte diapedesis

(2009) Hyun Wee et al.   EXPERIMENTAL AND MOLECULAR MEDICINE

Fatty acid binding protein 4 is a target of VEGF and a regulator of cell proliferation in endothelial cells

(2009) Harun Elmasri et al.   FASEB JOURNAL

Endothelial glycocalyx dimensions are reduced in growing collateral arteries and modulate leucocyte adhesion in arteriogenesis

(2009) Sebastian Grundmann et al.   JOURNAL OF CELLULAR AND MOLECULAR MEDICINE

Lactic Acid and Acidification Inhibit TNF Secretion and Glycolysis of Human Monocytes

(2009) K. Dietl et al.   JOURNAL OF IMMUNOLOGY

TNF primes endothelial cells for angiogenic sprouting by inducing a tip cell phenotype

(2008) R. C. A. Sainson et al.   BLOOD

Tumor angiogenesis and progression are enhanced by Sema4D produced by tumor-associated macrophages

(2008) Jose Rafael Sierra et al.   JOURNAL OF EXPERIMENTAL MEDICINE

Regulation of endothelial barrier function by reactive oxygen and nitrogen species

(2008) Adel Boueiz et al.   MICROVASCULAR RESEARCH

Del-1, an Endogenous Leukocyte-Endothelial Adhesion Inhibitor, Limits Inflammatory Cell Recruitment

(2008) E. Y. Choi et al.   SCIENCE