Atropo‐Enantioselective Oxidation‐Enabled Iridium(III)‐Catalyzed C−H Arylations with Aryl Boronic Esters

Recent Advances in Catalytic Asymmetric Construction of Atropisomers

(2021) Jun Kee Cheng et al.   CHEMICAL REVIEWS

Synthesis of Axially Chiral Biaryl-2-amines by PdII -Catalyzed Free-Amine-Directed Atroposelective C−H Olefination

(2020) Bei-Bei Zhan et al.   ANGEWANDTE CHEMIE-INTERNATIONAL EDITION

Rhodium(III)-Catalyzed Asymmetric Access to Spirocycles through C−H Activation and Axial-to-Central Chirality Transfer

(2020) Lingheng Kong et al.   ANGEWANDTE CHEMIE-INTERNATIONAL EDITION

Diverse Approaches for Enantioselective C–H Functionalization Reactions Using Group 9 CpxMIII Catalysts

(2020) Tatsuhiko Yoshino et al.   CHEMISTRY-A EUROPEAN JOURNAL

Ir-Catalyzed Atroposelective Desymmetrization of Heterobiaryls: Hydroarylation of Vinyl Ethers and Bicycloalkenes

(2020) Antonio Romero-Arenas et al.   JOURNAL OF THE AMERICAN CHEMICAL SOCIETY

Intermolecular Palladium(0)-Catalyzed Atropo-enantioselective C–H Arylation of Heteroarenes

(2020) Qui-Hien Nguyen et al.   JOURNAL OF THE AMERICAN CHEMICAL SOCIETY

Enantioselective Synthesis of Atropisomers with Multiple Stereogenic Axes

(2020) Xiaoze Bao et al.   ANGEWANDTE CHEMIE-INTERNATIONAL EDITION

Rhodium(III)‐Catalyzed Atroposelective Synthesis of Biaryls by C−H Activation and Intermolecular Coupling with Sterically Hindered Alkynes

(2020) Fen Wang et al.   ANGEWANDTE CHEMIE-INTERNATIONAL EDITION

Chiral cyclopentadienyl ligands: design, syntheses and applications in asymmetric catalysis

(2020) Nicolai Cramer et al.   ANGEWANDTE CHEMIE-INTERNATIONAL EDITION

Iridium-catalyzed acid-assisted asymmetric hydrogenation of oximes to hydroxylamines

(2020) Josep Mas-Roselló et al.   SCIENCE

Catalytic Enantioselective Functionalizations of C–H Bonds by Chiral Iridium Complexes

(2020) Łukasz Woźniak et al.   CHEMICAL REVIEWS

Rhodium-Catalyzed Atroposelective Oxidative C–H/C–H Cross-Coupling Reaction of 1-Aryl Isoquinoline Derivatives with Electron-Rich Heteroarenes

(2020) Qiang Wang et al.   JOURNAL OF THE AMERICAN CHEMICAL SOCIETY

Enantioselective Synthesis of Atropisomeric Anilides via Pd(II)-Catalyzed Asymmetric C–H Olefination

(2020) Qi-Jun Yao et al.   JOURNAL OF THE AMERICAN CHEMICAL SOCIETY

Rhodium‐Catalyzed Atroposelective Construction of Indoles via C‐H Bond Activation

(2020) Lincong Sun et al.   ANGEWANDTE CHEMIE-INTERNATIONAL EDITION

Enantioselective Synthesis of Azoniahelicenes by Rh-Catalyzed C–H Annulation with Alkynes

(2020) Qiang Wang et al.   JOURNAL OF THE AMERICAN CHEMICAL SOCIETY

Enantioselective Synthesis of Atropisomers Featuring Pentatomic Heteroaromatics by Pd-Catalyzed C–H Alkynylation

(2019) Shuo Zhang et al.   ACS Catalysis

Oxidatively Induced Reductive Elimination: Exploring the Scope and Catalyst Systems with Ir, Rh, and Ru Complexes

(2019) Jinwoo Kim et al.   JOURNAL OF THE AMERICAN CHEMICAL SOCIETY

Enantioselective Synthesis of Biaryl Atropisomers via Pd-Catalyzed C-H Olefination using Chiral Spiro Phosphoric Acid Ligands

(2019) Jun Luo et al.   ANGEWANDTE CHEMIE-INTERNATIONAL EDITION

Enantioselective Synthesis of C-N Axially Chiral N-Aryloxindoles by Asymmetric Rhodium-Catalyzed Dual C-H Activation

(2019) Honghe Li et al.   ANGEWANDTE CHEMIE-INTERNATIONAL EDITION

Enantioselective C-H Activation with Earth-Abundant 3d Transition Metals

(2019) Joachim Loup et al.   ANGEWANDTE CHEMIE-INTERNATIONAL EDITION

Rhodium-Catalyzed Atroposelective C–H Arylation: Efficient Synthesis of Axially Chiral Heterobiaryls

(2019) Qiang Wang et al.   JOURNAL OF THE AMERICAN CHEMICAL SOCIETY

Rh(III)-Catalyzed Asymmetric Synthesis of Axially Chiral Biindolyls by Merging C–H Activation and Nucleophilic Cyclization

(2019) Miaomiao Tian et al.   JOURNAL OF THE AMERICAN CHEMICAL SOCIETY

Construction of N–C Axial Chirality through Atroposelective C–H Olefination of N-Arylindoles by Palladium/Amino Acid Cooperative Catalysis

(2019) Jitan Zhang et al.   ORGANIC LETTERS

Ru-Catalyzed Deoxygenative Regioselective C8–H Arylation of Quinoline N-Oxides

(2019) Jinwoo Kim et al.   JOURNAL OF ORGANIC CHEMISTRY

Axially Chiral Dibenzazepinones via a Pd(0)-Catalyzed Atropo-enantioselective C-H Arylation

(2018) Nicolai Cramer et al.   ANGEWANDTE CHEMIE-INTERNATIONAL EDITION

Recent encounters with atropisomerism in drug discovery

(2018) Peter W. Glunz   BIOORGANIC & MEDICINAL CHEMISTRY LETTERS

Atropisomerism in medicinal chemistry: challenges and opportunities

(2018) Sean T Toenjes et al.   Future Medicinal Chemistry

Enantioselective C(sp3)‒H bond activation by chiral transition metal catalysts

(2018) Tyler G. Saint-Denis et al.   SCIENCE

C-H Bond Activation for the Synthesis of Heterocyclic Atropisomers Yields Hedgehog Pathway Inhibitors

(2018) Herbert Waldmann et al.   ANGEWANDTE CHEMIE-INTERNATIONAL EDITION

Access to P - and Axially Chiral Biaryl Phosphine Oxides by Enantioselective Cpx IrIII -Catalyzed C−H Arylations

(2018) Yun-Suk Jang et al.   ANGEWANDTE CHEMIE-INTERNATIONAL EDITION

Cluster Preface: Atropisomerism

(2018) Jay Siegel   SYNLETT

Pd-Catalyzed Atroposelective C−H Allylation through β-O Elimination: Diverse Synthesis of Axially Chiral Biaryls

(2018) Gang Liao et al.   ANGEWANDTE CHEMIE-INTERNATIONAL EDITION

Palladium-Catalyzed ortho–C-H Arylation of Acetophenone Oxime Ethers with Aryl Pinacol Boronic Esters

(2017) Daggula Mallikarjuna Reddy et al.   JOURNAL OF ORGANIC CHEMISTRY

Iridium-catalysed arylation of C–H bonds enabled by oxidatively induced reductive elimination

(2017) Kwangmin Shin et al.   Nature Chemistry

A β-Carbon elimination strategy for convenient in situ access to cyclopentadienyl metal complexes

(2017) G. Smits et al.   Chemical Science

Axially Chiral P,N-Ligands: Some Recent Twists and Turns

(2017) Balaji V. Rokade et al.   ACS Catalysis

Enantioselective Synthesis of Indole-Based Biaryl Atropisomers via Palladium-Catalyzed Dynamic Kinetic Intramolecular C–H Cyclization

(2017) Congfa He et al.   ACS Catalysis

Asymmetric Catalysis Powered by Chiral Cyclopentadienyl Ligands

(2016) Christopher G. Newton et al.   JOURNAL OF THE AMERICAN CHEMICAL SOCIETY

Synthesis and Application of Chiral Spiro Cp Ligands in Rhodium-Catalyzed Asymmetric Oxidative Coupling of Biaryl Compounds with Alkenes

(2016) Jun Zheng et al.   JOURNAL OF THE AMERICAN CHEMICAL SOCIETY

Ruthenium(II)-Catalyzed Regioselective C–H Arylation of Cyclic and N,N-Dialkyl Benzamides with Boronic Acids by Weak Coordination

(2016) Pradeep Nareddy et al.   ACS Catalysis

Chiral Cyclopentadienyls: Enabling Ligands for Asymmetric Rh(III)-Catalyzed C–H Functionalizations

(2015) Baihua Ye et al.   ACCOUNTS OF CHEMICAL RESEARCH

Chiral Cyclopentadienyl Iridium(III) Complexes Promote Enantioselective Cycloisomerizations Giving Fused Cyclopropanes

(2015) Michael Dieckmann et al.   ANGEWANDTE CHEMIE-INTERNATIONAL EDITION

Rational Design of a Fluorescent Sensor to Simultaneously Determine Both the Enantiomeric Composition and the Concentration of Chiral Functional Amines

(2015) Kaili Wen et al.   JOURNAL OF THE AMERICAN CHEMICAL SOCIETY

A twist of nature – the significance of atropisomers in biological systems

(2015) Jamie E. Smyth et al.   NATURAL PRODUCT REPORTS

Chiral Cyclopentadienyl Ligands Enable a Rhodium(III)-Catalyzed Enantioselective Access to Hydroxychromanes and Phthalides

(2015) Nicolai Cramer et al.   SYNLETT

Palladium-Catalysed, Directed CH Coupling with Organometallics

(2014) Ramesh Giri et al.   ADVANCED SYNTHESIS & CATALYSIS

Construction of Axial Chirality by Rhodium-Catalyzed Asymmetric Dehydrogenative Heck Coupling of Biaryl Compounds with Alkenes

(2014) Jun Zheng et al.   ANGEWANDTE CHEMIE-INTERNATIONAL EDITION

Pd(II)-Catalyzed Intermolecular Direct C–H Bond Iodination: An Efficient Approach toward the Synthesis of Axially Chiral Compounds via Kinetic Resolution

(2014) De-Wei Gao et al.   ACS Catalysis

Synthesis of binaphthyl based phosphine and phosphite ligands

(2013) Mariette M. Pereira et al.   CHEMICAL SOCIETY REVIEWS

Biological Stereoselectivity of Atropisomeric Natural Products and Drugs

(2013) Arie Zask et al.   CHIRALITY

A Tunable Class of Chiral Cp Ligands for Enantioselective Rhodium(III)-Catalyzed C–H Allylations of Benzamides

(2013) Baihua Ye et al.   JOURNAL OF THE AMERICAN CHEMICAL SOCIETY

Aromatic C–H coupling with hindered arylboronic acids by Pd/Fe dual catalysts

(2013) Kazuya Yamaguchi et al.   Chemical Science

1,2-Di(phenylethynyl)ethenes with axially chiral, 2,2′-bridged 1,1′-binaphthyl substituents: potent cholesteric liquid-crystal inducers

(2012) Yi-Lin Wu et al.   ORGANIC & BIOMOLECULAR CHEMISTRY

Chiral Cyclopentadienyl Ligands as Stereocontrolling Element in Asymmetric C-H Functionalization

(2012) B. Ye et al.   SCIENCE

Hindered biaryls by C–H coupling: bisoxazoline-Pd catalysis leading to enantioselective C–H coupling

(2012) Kazuya Yamaguchi et al.   Chemical Science

Assessing Atropisomer Axial Chirality in Drug Discovery and Development

(2011) Steven R. LaPlante et al.   JOURNAL OF MEDICINAL CHEMISTRY

Atroposelective Total Synthesis of Axially Chiral Biaryl Natural Products

(2010) Gerhard Bringmann et al.   CHEMICAL REVIEWS

The Challenge of Atropisomerism in Drug Discovery

(2009) Jonathan Clayden et al.   ANGEWANDTE CHEMIE-INTERNATIONAL EDITION

Pd-Catalyzed C−H Functionalizations ofO-Methyl Oximes with Arylboronic Acids

(2009) Chang-Liang Sun et al.   ORGANIC LETTERS