Enantioselective Construction of 5‐6‐5 Tricyclic Lactone Framework Bearing a Quaternary Bridgehead Carbon via Rh‐Catalyzed Asymmetric [2+2+2] Cycloaddition of Enediynes

Rhodium‐Catalyzed Asymmetric [2+2+2] Cycloaddition of 1,6‐Enynes with Racemic Secondary Allylic Alcohols through Kinetic Resolution

(2020) Shunsuke Suzuki et al.   CHEMISTRY-A EUROPEAN JOURNAL

Mechanistic Studies of Transition-Metal-Catalyzed [2 + 2 + 2] Cycloaddition Reactions

(2020) Anna Roglans et al.   CHEMICAL REVIEWS

The search for, and chemistry and mechanism of, neurotrophic natural products

(2020) Yoshiyasu Fukuyama et al.   Journal of Natural Medicines

Catalytic Enantioselective Construction of Spiro Quaternary Carbon Stereocenters

(2019) Peng-Wei Xu et al.   ACS Catalysis

Cyclometalated Iridium–PhanePhos Complexes Are Active Catalysts in Enantioselective Allene–Fluoral Reductive Coupling and Related Alcohol-Mediated Carbonyl Additions That Form Acyclic Quaternary Carbon Stereocenters

(2019) Leyah A. Schwartz et al.   JOURNAL OF THE AMERICAN CHEMICAL SOCIETY

Diastereoselective Methylation at the Congested β-Position of a Butenolide Ring: Studies toward the Synthesis of seco-Prezizaane-Type Sesquiterpenes

(2019) Tomoyoshi Kawamura et al.   JOURNAL OF ORGANIC CHEMISTRY

Towards the online computer-aided design of catalytic pockets

(2019) Laura Falivene et al.   Nature Chemistry

Asymmetric Synthesis of a Fused tricyclic Hydronaphthofuran Scaffold by Desymmetric [2+2+2] Cycloaddition

(2019) Qi Teng et al.   ANGEWANDTE CHEMIE-INTERNATIONAL EDITION

Jiadifenolide induces the expression of cellular communication network factor (CCN) genes, and CCN2 exhibits neurotrophic activity in neuronal precursor cells derived from human induced pluripotent stem cells

(2019) Masaki Shoji et al.   BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS

Pharmacological characterization of the neurotrophic sesquiterpene jiadifenolide reveals a non-convulsant signature and potential for progression in neurodegenerative disease studies

(2018) Jeffrey M. Witkin et al.   BIOCHEMICAL PHARMACOLOGY

Rhodium-Catalyzed Asymmetric [2 + 2 + 2] Cycloaddition of Unsymmetrical α,ω-Diynes with Acenaphthylene

(2018) Yukimasa Aida et al.   JOURNAL OF ORGANIC CHEMISTRY

Chiral Induction in [2+2+2] Cycloaddition Reactions

(2018) Anna Pla-Quintana et al.   Asian Journal of Organic Chemistry

Recent topics of Cp ∗ RuCl-catalyzed annulation reactions

(2017) Yoshihiko Yamamoto   TETRAHEDRON LETTERS

Synthetic Strategies toward Natural Products Containing Contiguous Stereogenic Quaternary Carbon Atoms

(2016) Martin Büschleb et al.   ANGEWANDTE CHEMIE-INTERNATIONAL EDITION

Isolation and Asymmetric Total Synthesis of Perforanoid A

(2016) Chao Lv et al.   ANGEWANDTE CHEMIE-INTERNATIONAL EDITION

Catalytic Enantioselective Desymmetrization Reactions to All-Carbon Quaternary Stereocenters

(2016) Xing-Ping Zeng et al.   CHEMICAL REVIEWS

Alkenes in [2+2+2] Cycloadditions

(2016) Gema Domínguez et al.   CHEMISTRY-A EUROPEAN JOURNAL

Neurite outgrowth enhancement by jiadifenolide: possible targets

(2016) R. A. Shenvi   NATURAL PRODUCT REPORTS

Rhodium-Catalyzed Asymmetric [2 + 2 + 2] Cycloaddition of α,ω-Diynes with Unsymmetrical 1,2-Disubstituted Alkenes

(2016) Yukimasa Aida et al.   ORGANIC LETTERS

SambVca 2. A Web Tool for Analyzing Catalytic Pockets with Topographic Steric Maps

(2016) Laura Falivene et al.   ORGANOMETALLICS

Catalytic Enantioselective Construction of Quaternary Stereocenters: Assembly of Key Building Blocks for the Synthesis of Biologically Active Molecules

(2015) Yiyang Liu et al.   ACCOUNTS OF CHEMICAL RESEARCH

Direct construction of vicinal all-carbon quaternary stereocenters in natural product synthesis

(2015) Rong Long et al.   NATURAL PRODUCT REPORTS

A lactone-fused cyclohexadiene as a versatile platform for diversified synthesis of 5,6,5-tricyclic scaffolds

(2015) M. Shibuya et al.   ORGANIC & BIOMOLECULAR CHEMISTRY

Highly Chemo-, Regio-, and Enantioselective Rhodium-Catalyzed Cross-Cyclotrimerization of Two Different Alkynes with Alkenes

(2014) Jun Hara et al.   ANGEWANDTE CHEMIE-INTERNATIONAL EDITION

Recent Advances in Stereoselective [2+2+2] Cycloadditions

(2014) Muriel Amatore et al.   EUROPEAN JOURNAL OF ORGANIC CHEMISTRY

Catalytic enantioselective synthesis of quaternary carbon stereocentres

(2014) Kyle W. Quasdorf et al.   NATURE

IlliciumSesquiterpenes: Divergent Synthetic Strategy and Neurotrophic Activity Studies

(2013) Lynnie Trzoss et al.   CHEMISTRY-A EUROPEAN JOURNAL

Catalytic Version of Enediyne Cobalt-Mediated Cycloaddition and Selective Access to Unusual Bicyclic Trienes

(2013) Sandrine Ventre et al.   CHEMISTRY-A EUROPEAN JOURNAL

P-Stereogenic Secondary Iminophosphorane Ligands and Their Rhodium(I) Complexes: Taking Advantage of NH/PH Tautomerism

(2012) Thierry León et al.   ANGEWANDTE CHEMIE-INTERNATIONAL EDITION

Facile Synthesis of Cyclic Polyphenylenes by Consecutive Inter- and Intramolecular Cycloadditions of ortho-, meta-, and para-Phenylene-Tethered Triynes

(2012) Takanori Shibata et al.   SYNTHESIS-STUTTGART

Rhodium(I)-Catalyzed Ene-Allene-Allene [2+2+2] Cycloadditions: Stereoselective Synthesis of Complex trans-Fused Carbocycles

(2011) Andrew T. Brusoe et al.   ANGEWANDTE CHEMIE-INTERNATIONAL EDITION

Rhodium-Catalyzed Asymmetric Formal Olefination or Cycloaddition: 1,3-Dicarbonyl Compounds Reacting with 1,6-Diynes or 1,6-Enynes

(2011) Takeshi Suda et al.   ANGEWANDTE CHEMIE-INTERNATIONAL EDITION

Intramolecular [2+2+2] Cycloaddition Reactions of Yne-ene-yne and Yne-yne-ene Enediynes Catalysed by RhI: Experimental and Theoretical Mechanistic Studies

(2011) Anna Dachs et al.   CHEMISTRY-A EUROPEAN JOURNAL

RhCl(PPh3)3-Catalyzed Intramolecular Cycloaddition of Enediynes: The Nature of the Tether and Substituents Controls the Reaction Mechanism

(2011) Anna Dachs et al.   ORGANOMETALLICS

Regiodivergent Ligand-Controlled Rhodium-Catalyzed [(2+2)+2] Carbocyclization Reactions with Alkyl Substituted Methyl Propiolates

(2010) P. Andrew Evans et al.   ANGEWANDTE CHEMIE-INTERNATIONAL EDITION

Synthesis of Unique Scaffolds via Diels−Alder Cycloadditions of Tetrasubstituted Cyclohexadienes

(2010) Amanda L. Jones et al.   ORGANIC LETTERS

A Straightforward Procedure for the [2+2+2] Cycloaddition of Enediynes

(2009) Anaïs Geny et al.   ADVANCED SYNTHESIS & CATALYSIS

Intramolecular Rhodium-Catalyzed [2+2+2] Cyclizations of Diynes with Enones

(2009) Amanda L. Jones et al.   JOURNAL OF ORGANIC CHEMISTRY

Novel Pentacyclicseco-Prezizaane-Type Sesquiterpenoids with Neurotrophic Properties fromIllicium jiadifengpi

(2009) Miwa Kubo et al.   ORGANIC LETTERS

Highly Regio-, Diastereo-, and Enantioselective [2+2+2] Cycloaddition of 1,6-Enynes with Electron-Deficient Ketones Catalyzed by a Cationic RhI/H8-binap Complex

(2008) Ken Tanaka et al.   ANGEWANDTE CHEMIE-INTERNATIONAL EDITION

Cycloisomerization of 1,n-Enynes: Challenging Metal-Catalyzed Rearrangements and Mechanistic Insights

(2008) Véronique Michelet et al.   ANGEWANDTE CHEMIE-INTERNATIONAL EDITION

Fused tetracycles with a benzene or cyclohexadiene core: [2 + 2 + 2] cycloadditions on macrocyclic systems

(2008) Sandra Brun et al.   CHEMICAL COMMUNICATIONS

Rhodium-catalyzed enantio- and diastereoselective intramolecular [2 + 2 + 2] cycloaddition of unsymmetrical dienynes

(2008) Hiromi Sagae et al.   CHEMICAL COMMUNICATIONS

Transition-Metal-Catalyzed Enantioselective [2+2+2] Cycloadditions for the Synthesis of Axially Chiral Biaryls

(2008) Ken Tanaka   Chemistry-An Asian Journal

Recent advances in enantioselective [2 + 2 + 2] cycloaddition

(2008) Takanori Shibata et al.   ORGANIC & BIOMOLECULAR CHEMISTRY