Alkenes in [2+2+2] Cycloadditions

Rhodium-Catalyzed [3+2+2] and [2+2+2] Cycloadditions of Two Alkynes with Cyclopropylideneacetamides

(2015) Tomoka Yoshida et al.   ANGEWANDTE CHEMIE-INTERNATIONAL EDITION

Ni-Catalyzed Synthesis of Fluoroarenes via [2+2+2] Cycloaddition Involving α-Fluorine Elimination

(2015) Takeshi Fujita et al.   CHEMISTRY-A EUROPEAN JOURNAL

Rhodium(III)-Catalyzed [2+2+2] Cyclotrimerization of Diynes with Maleic Anhydrides as Alkyne Equivalents

(2015) Takanori Matsuda et al.   EUROPEAN JOURNAL OF ORGANIC CHEMISTRY

Niobium Complexes in Organic Transformations: From Stoichiometric Reactions to Catalytic [2+2+2] Cycloaddition Reactions

(2015) Yasushi Satoh et al.   EUROPEAN JOURNAL OF ORGANIC CHEMISTRY

Ruthenium Alkylidene-Catalyzed Reaction of 1,6-Heptadiynes with Alkenes

(2015) Silvia Alvarez et al.   JOURNAL OF ORGANIC CHEMISTRY

Nickel(0)/N-Heterocyclic Carbene-Catalyzed Asymmetric [2 + 2 + 2] Cycloaddition of Two Enones and an Alkyne: Access to Cyclohexenes with Four Contiguous Stereogenic Centers

(2015) Ravindra Kumar et al.   ORGANIC LETTERS

Dehydrogenative [2 + 2 + 2] Cycloaddition of Cyano-yne-allene Substrates: Convenient Access to 2,6-Naphthyridine Scaffolds

(2015) Ewelina Haraburda et al.   ORGANIC LETTERS

Substituted 1,3-cyclohexadiene synthesis by NHC–Nickel(0) catalyzed [2+2+2] cycloaddition of 1,n-Enyne

(2015) Jian-Ping Zhao et al.   TETRAHEDRON

Gold(i)-catalyzed [2 + 2 + 2] cycloaddition of allenamides, alkenes and aldehydes: a straightforward approach to tetrahydropyrans

(2015) Hélio Faustino et al.   Chemical Science

Stereospecific and Stereoselective Rhodium(I)-Catalyzed Intramolecular [2+2+2] Cycloaddition of Allene-Ene-Ynes: Construction of Bicyclo[4.1.0]heptenes

(2014) Yuu Ohta et al.   ANGEWANDTE CHEMIE-INTERNATIONAL EDITION

Highly Chemo-, Regio-, and Enantioselective Rhodium-Catalyzed Cross-Cyclotrimerization of Two Different Alkynes with Alkenes

(2014) Jun Hara et al.   ANGEWANDTE CHEMIE-INTERNATIONAL EDITION

Rhodium-catalyzed Enantioselective [2 + 2 + 2] Cycloaddition of Tosylamide-linked 5-Allenal and 5-Allenone with Internal Alkynes

(2014) Kazuki Sakashita et al.   CHEMISTRY LETTERS

Stereoselective Rhodium-Catalysed [2+2+2] Cycloaddition of Linear Allene-Ene/Yne-Allene Substrates: Reactivity and Theoretical Mechanistic Studies

(2014) Ewelina Haraburda et al.   CHEMISTRY-A EUROPEAN JOURNAL

Catalytic [2 + 2 + 2] Cycloaddition of Benzothiophene Dioxides with α,ω-Diynes for the Synthesis of Condensed Polycyclic Compounds

(2014) Yu-ki Tahara et al.   ORGANIC LETTERS

A Catalytic Asymmetric Synthesis of Polysubstituted Piperidines Using a Rhodium(I)-Catalyzed [2+2+2] Cycloaddition Employing a Cleavable Tether

(2013) Timothy J. Martin et al.   ANGEWANDTE CHEMIE-INTERNATIONAL EDITION

Nickel-catalyzed [2 + 2 + 2] Cycloaddition Reaction of Isocyanates with 1,3-Dienes

(2013) Masao Morimoto et al.   CHEMISTRY LETTERS

Intermolecular Gold-Catalyzed Cycloaddition of Alkynes with Oxoalkenes

(2013) Carla Obradors et al.   CHEMISTRY-A EUROPEAN JOURNAL

Catalytic, Asymmetric Indolizidinone Aza-Quaternary Stereocenter Synthesis: Expedient Synthesis of the Cylindricine Alkaloid Core

(2013) Derek M. Dalton et al.   ORGANIC LETTERS

Construction of tricyclic pyran derivatives through intramolecular [2+2+2] cycloaddition of allenynes with tethered aldehydes

(2013) Yoshihiro Oonishi et al.   TETRAHEDRON

Rhodium-Catalyzed Regio-, Diastereo-, and Enantioselective [2+2+2] Cycloaddition of 1,6-Enynes with Acrylamides

(2012) Koji Masutomi et al.   ANGEWANDTE CHEMIE-INTERNATIONAL EDITION

Gold-catalyzed diastereoselective [2+2+2]-cycloaddition of 1,7-enynes with carbonyl compounds

(2012) Deepak B. Huple et al.   CHEMICAL COMMUNICATIONS

Enantioselective Intermolecular [2 + 2 + 2] Cycloadditions of Ene–Allenes with Allenoates

(2012) Andrew T. Brusoe et al.   ORGANIC LETTERS

Rhodium(I)-Catalyzed Ene-Allene-Allene [2+2+2] Cycloadditions: Stereoselective Synthesis of Complex trans-Fused Carbocycles

(2011) Andrew T. Brusoe et al.   ANGEWANDTE CHEMIE-INTERNATIONAL EDITION

Enantioselective Construction of Bridged Multicyclic Skeletons: Intermolecular [2+2+2] Cycloaddition/Intramolecular Diels-Alder Reaction Cascade

(2011) Masayuki Kobayashi et al.   ANGEWANDTE CHEMIE-INTERNATIONAL EDITION

Gold-Catalyzed Intermolecular [4+2] and [2+2+2] Cycloadditions of Ynamides with Alkenes

(2011) Ramesh B. Dateer et al.   ANGEWANDTE CHEMIE-INTERNATIONAL EDITION

Preparation and synthetic applications of alkene complexes of group 9 transition metals in [2+2+2] cycloaddition reactions

(2011) Nico Weding et al.   CHEMICAL SOCIETY REVIEWS

Intramolecular [2+2+2] Cycloaddition Reactions of Yne-ene-yne and Yne-yne-ene Enediynes Catalysed by RhI: Experimental and Theoretical Mechanistic Studies

(2011) Anna Dachs et al.   CHEMISTRY-A EUROPEAN JOURNAL

Rhodium-Catalyzed Decarboxylative Cycloaddition Route to Substituted Anilines

(2011) Kainan Zhang et al.   JOURNAL OF ORGANIC CHEMISTRY

Active Low-Valent Niobium Catalysts from NbCl5and Hydrosilanes for Selective Intermolecular Cycloadditions

(2011) Yasushi Satoh et al.   JOURNAL OF ORGANIC CHEMISTRY

An aerobic [2 + 2 + 2] Cyclization via Chloropalladation: From 1,6-Diynes and Acrylates to Substituted Aromatic Carbocycles

(2011) Peng Zhou et al.   JOURNAL OF ORGANIC CHEMISTRY

NbCl3-Catalyzed Three-Component [2 + 2 + 2] Cycloaddition Reaction of Terminal Alkynes, Internal Alkynes, and Alkenes to 1,3,4,5-Tetrasubstituted 1,3-Cyclohexadienes

(2011) Yasushi Satoh et al.   ORGANIC LETTERS

Control over [2+2+2] and Carbonylative [4+2] Cycloaddition by CO Pressure in Co-Catalyzed Cycloaddition between Internal Diynes and Cyclopentadiene

(2010)   BULLETIN OF THE KOREAN CHEMICAL SOCIETY

Stereoselective transition metal-catalysed higher-order carbocyclisation reactions

(2010) Phillip A. Inglesby et al.   CHEMICAL SOCIETY REVIEWS

Cobalt-Mediated Linear 2:1 Co-oligomerization of Alkynes with Enol Ethers to Give 1-Alkoxy-1,3,5-Trienes: A Missing Mode of Reactivity

(2010) David Lebœuf et al.   CHEMISTRY-A EUROPEAN JOURNAL

NbCl3-Catalyzed Intermolecular [2+2+2] Cycloaddition of Alkynes and α,ω-Dienes: Highly Chemo- and Regioselective Formation of 5-ω-Alkenyl-1,4-substituted-1,3-cyclohexadiene Derivatives

(2010) Yasushi Obora et al.   JOURNAL OF ORGANIC CHEMISTRY

Highly Chemoselective Palladium-Catalyzed Cross-Trimerization between Alkyne and Alkenes Leading to 1,3,5-Trienes or 1,2,4,5-Tetrasubstituted Benzenes with Dioxygen

(2010) Peng Zhou et al.   JOURNAL OF ORGANIC CHEMISTRY

PdCl2(HNMe2)2-Catalyzed Highly Selective Cross [2 + 2 + 2] Cyclization of Alkynoates and Alkenes under Molecular Oxygen

(2010) Yanxia Shen et al.   JOURNAL OF ORGANIC CHEMISTRY

Enantioselective [2 + 2 + 2] Cycloaddition Reaction of Isocyanates and Allenes Catalyzed by Nickel

(2010) Tomoya Miura et al.   JOURNAL OF THE AMERICAN CHEMICAL SOCIETY

Nickel-Catalyzed [2 + 2 + 2] Cycloaddition of Two Enones and an Alkyne

(2010) Sensuke Ogoshi et al.   ORGANIC LETTERS

Chiral N-phosphino sulfinamide ligands in rhodium(I)-catalyzed [2+2+2] cycloaddition reactions

(2010) Sandra Brun et al.   TETRAHEDRON

A Straightforward Procedure for the [2+2+2] Cycloaddition of Enediynes

(2009) Anaïs Geny et al.   ADVANCED SYNTHESIS & CATALYSIS

Nickel-Catalyzed Three-Component [2+2+2] Cycloaddition Reaction of Arynes, Alkenes, and Alkynes

(2009) Zaozao Qiu et al.   ANGEWANDTE CHEMIE-INTERNATIONAL EDITION

Total Synthesis of Indolizidine Alkaloid (−)-209D: Overriding Substrate Bias in the Asymmetric Rhodium-Catalyzed [2+2+2] Cycloaddition

(2009) Robert T. Yu et al.   ANGEWANDTE CHEMIE-INTERNATIONAL EDITION

Palladium-Catalyzed Cocyclotrimerization of Allenes with Arynes: Selective Synthesis of Phenanthrenes

(2009) Yi-Lin Liu et al.   JOURNAL OF ORGANIC CHEMISTRY

Enantioselective Rhodium-Catalyzed [2 + 2 + 2] Cycloadditions of Terminal Alkynes and Alkenyl Isocyanates: Mechanistic Insights Lead to a Unified Model that Rationalizes Product Selectivity

(2009) Derek M. Dalton et al.   JOURNAL OF THE AMERICAN CHEMICAL SOCIETY

A New Route to Substituted Phenols by Cationic Rhodium(I)/BINAP Complex-Catalyzed Decarboxylative [2 + 2 + 2] Cycloaddition

(2009) Hiromi Hara et al.   ORGANIC LETTERS

Commercially available liquid enol ethers and acetates as gaseous alkyne equivalents in cationic Rh(I)/BINAP-catalyzed chemo- and regioselective formal cross-alkyne cyclotrimerizations

(2009) Hiromi Hara et al.   TETRAHEDRON

Rhodium-catalyzed enantio- and diastereoselective intramolecular [2 + 2 + 2] cycloaddition of unsymmetrical dienynes

(2008) Hiromi Sagae et al.   CHEMICAL COMMUNICATIONS

Recent Advances in “Formal” Ruthenium-Catalyzed [2+2+2] Cycloaddition Reactions of Diynes to Alkenes

(2008) Silvia García-Rubín et al.   CHEMISTRY-A EUROPEAN JOURNAL

Transition-Metal-Catalyzed Enantioselective [2+2+2] Cycloadditions for the Synthesis of Axially Chiral Biaryls

(2008) Ken Tanaka   Chemistry-An Asian Journal

Cobalt-Catalyzed Intermolecular [2 + 2 + 2] Cycloaddition for the Synthesis of 1,3-Cyclohexadienes

(2008) Gerhard Hilt et al.   JOURNAL OF ORGANIC CHEMISTRY

“Formal” and Standard Ruthenium-Catalyzed [2 + 2 + 2] Cycloaddition Reaction of 1,6-Diynes to Alkenes:  A Mechanistic Density Functional Study

(2008) Jesús A. Varela et al.   JOURNAL OF ORGANIC CHEMISTRY

CpRuCl- and CpCo-catalyzed or mediated cyclotrimerizations of alkynes and [2+2+2] cycloadditions of alkynes to alkenes: A comparative DFT study

(2008) Jesús A. Varela et al.   JOURNAL OF ORGANOMETALLIC CHEMISTRY

Highly diastereo- and enantioselective construction of both central and axial chiralities by Rh-catalyzed [2 + 2 + 2] cycloaddition

(2008) Takanori Shibata et al.   ORGANIC & BIOMOLECULAR CHEMISTRY

Recent advances in enantioselective [2 + 2 + 2] cycloaddition

(2008) Takanori Shibata et al.   ORGANIC & BIOMOLECULAR CHEMISTRY

NbCl3-catalyzed [2+2+2] intermolecular cycloaddition of alkynes and alkenes to 1,3-cyclohexadiene derivatives

(2008) Yasushi Obora et al.   ORGANIC & BIOMOLECULAR CHEMISTRY

Liquid Enol Ethers and Acetates as Gaseous Alkyne Equivalents in Rh-Catalyzed Chemo- and Regioselective Formal Cross-Alkyne Cyclotrimerization

(2008) Hiromi Hara et al.   ORGANIC LETTERS

Enantioselective synthesis of α,α-disubstituted α-amino acids by Rh-catalyzed [2+2+2] cycloaddition of 1,6-diynes with protected dehydroamino acid

(2008) Ken Tanaka et al.   TETRAHEDRON