标题
The past, present, and future of breast cancer models for nanomedicine development
作者
关键词
Breast cancer, Metastasis, Pre-clinical models, Nanomedicines, Organoids, Patient-derived xenografts, Animal models, Biomarkers
出版物
ADVANCED DRUG DELIVERY REVIEWS
Volume 173, Issue -, Pages 306-330
出版商
Elsevier BV
发表日期
2021-03-31
DOI
10.1016/j.addr.2021.03.018
参考文献
相关参考文献
注意:仅列出部分参考文献,下载原文获取全部文献信息。- Breast tumor-on-chip models: From disease modeling to personalized drug screening
- (2021) Bano Subia et al. JOURNAL OF CONTROLLED RELEASE
- Cancer‐on‐a‐Chip for Modeling Immune Checkpoint Inhibitor and Tumor Interactions
- (2021) Xing Jiang et al. Small
- Polymer Conjugation of Docosahexaenoic Acid Potentiates Cardioprotective Therapy in Preclinical Models of Myocardial Ischemia/Reperfusion Injury
- (2021) Sandra Tejedor et al. Advanced Healthcare Materials
- Cancer statistics, 2020
- (2020) Rebecca L. Siegel et al. CA-A CANCER JOURNAL FOR CLINICIANS
- Genetically Engineered Pigs to Study Cancer
- (2020) Daniela Kalla et al. INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES
- Orthotopic Implantation Achieves Better Engraftment and Faster Growth Than Subcutaneous Implantation in Breast Cancer Patient-Derived Xenografts
- (2020) Maiko Okano et al. JOURNAL OF MAMMARY GLAND BIOLOGY AND NEOPLASIA
- The entry of nanoparticles into solid tumours
- (2020) Shrey Sindhwani et al. NATURE MATERIALS
- Highly efficient and tumor-selective nanoparticles for dual-targeted immunogene therapy against cancer
- (2020) Kuan-Wei Huang et al. Science Advances
- Nanomedicine and cancer immunotherapy
- (2020) Hai-jun Yu et al. ACTA PHARMACOLOGICA SINICA
- Best Practices for Preclinical In Vivo Testing of Cancer Nanomedicines
- (2020) Danielle M. Valcourt et al. Advanced Healthcare Materials
- Challenges in nanomedicine clinical translation
- (2020) Josbert M. Metselaar et al. Drug Delivery and Translational Research
- Nanoparticle interactions with immune cells dominate tumor retention and induce T cell–mediated tumor suppression in models of breast cancer
- (2020) Preethi Korangath et al. Science Advances
- Nanomedicine-based drug delivery towards tumor biological and immunological microenvironment
- (2020) Jin Li et al. Acta Pharmaceutica Sinica B
- Naturally-Occurring Canine Mammary Tumors as a Translational Model for Human Breast Cancer
- (2020) Mark Gray et al. Frontiers in Oncology
- Exploiting the dynamics of the EPR effect and strategies to improve the therapeutic effects of nanomedicines by using EPR effect enhancers
- (2020) Jun Fang et al. ADVANCED DRUG DELIVERY REVIEWS
- Translational considerations in nanomedicine: The oncology perspective
- (2020) Alberto A. Gabizon et al. ADVANCED DRUG DELIVERY REVIEWS
- Mouse Tumor Models for Advanced Cancer Immunotherapy
- (2020) Daria S. Chulpanova et al. INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES
- Ag/Au Bimetallic Nanoparticles Inhibit Tumor Growth and Prevent Metastasis in a Mouse Model
- (2020) Hector Katifelis et al. International Journal of Nanomedicine
- Engineering peptide-targeted liposomal nanoparticles optimized for improved selectivity for HER2-positive breast cancer cells to achieve enhanced in vivo efficacy
- (2020) Baksun Kim et al. JOURNAL OF CONTROLLED RELEASE
- The importance of spheroids in analyzing nanomedicine efficacy
- (2020) Inês Mó et al. Nanomedicine
- A phase I dose-escalation and pharmacokinetic study of a micellar nanoparticle with entrapped docetaxel (CPC634) in patients with advanced solid tumours
- (2020) Florence Atrafi et al. JOURNAL OF CONTROLLED RELEASE
- Somatic cell-derived organoids as prototypes of human epithelial tissues and diseases
- (2020) Masayuki Fujii et al. NATURE MATERIALS
- Bone metastasis is associated with acquisition of mesenchymal phenotype and immune suppression in a model of spontaneous breast cancer metastasis
- (2020) Lea Monteran et al. Scientific Reports
- Zebrafish as a preclinical in vivo screening model for nanomedicines
- (2019) Sandro Sieber et al. ADVANCED DRUG DELIVERY REVIEWS
- Therapeutic impact of Nintedanib with paclitaxel and/or a PD-L1 antibody in preclinical models of orthotopic primary or metastatic triple negative breast cancer
- (2019) Elaine Reguera-Nuñez et al. JOURNAL OF EXPERIMENTAL & CLINICAL CANCER RESEARCH
- Dual complementary liposomes inhibit triple-negative breast tumor progression and metastasis
- (2019) Peng Guo et al. Science Advances
- Nanoparticles promote in vivo breast cancer cell intravasation and extravasation by inducing endothelial leakiness
- (2019) Fei Peng et al. Nature Nanotechnology
- Clinical cancer nanomedicine
- (2019) Joy Wolfram et al. Nano Today
- A pipeline for rapidly generating genetically engineered mouse models of pancreatic cancer using in vivo CRISPR-Cas9-mediated somatic recombination
- (2019) Noboru Ideno et al. LABORATORY INVESTIGATION
- Breast Cancer Treatment
- (2019) Adrienne G. Waks et al. JAMA-JOURNAL OF THE AMERICAN MEDICAL ASSOCIATION
- Characterization of Triple-Negative Breast Cancer Preclinical Models Provides Functional Evidence of Metastatic Progression
- (2019) Juan J. Arroyo-Crespo et al. INTERNATIONAL JOURNAL OF CANCER
- Establishment and characterization of a patient-derived circulating lung tumor cell line in vitro and in vivo
- (2019) Zujun Que et al. Cancer Cell International
- Combining Nanomedicine and Immunotherapy
- (2019) Yang Shi et al. ACCOUNTS OF CHEMICAL RESEARCH
- Concepts of nanoparticle cellular uptake, intracellular trafficking, and kinetics in nanomedicine
- (2019) Nathan D. Donahue et al. ADVANCED DRUG DELIVERY REVIEWS
- Intraductal Adaptation of the 4T1 Mouse Model of Breast Cancer Reveals Effects of the Epithelial Microenvironment on Tumor Progression and Metastasis
- (2019) HUDA I. ATIYA et al. ANTICANCER RESEARCH
- Nanomedicines for Reactive Oxygen Species Mediated Approach: An Emerging Paradigm for Cancer Treatment
- (2019) Seunglee Kwon et al. ACCOUNTS OF CHEMICAL RESEARCH
- The role of mouse tumour models in the discovery and development of anticancer drugs
- (2019) Christopher R. Ireson et al. BRITISH JOURNAL OF CANCER
- Smart nanomedicine agents for cancer, triggered by pH, glutathione, H2O2, or H2S
- (2019) Yaping Li et al. International Journal of Nanomedicine
- Alendronate-Modified Polymeric Micelles for the Treatment of Breast Cancer Bone Metastasis
- (2019) Tong Liu et al. MOLECULAR PHARMACEUTICS
- Gold Nanorod-Assisted Photothermal Therapy Decreases Bleeding during Breast Cancer Surgery in Dogs and Cats
- (2019) Moustafa R. K. Ali et al. Cancers
- Patient-Derived Xenograft Models of Breast Cancer and Their Application
- (2019) Murayama et al. Cells
- Human Organoids: Tools for Understanding Biology and Treating Diseases
- (2019) Frans Schutgens et al. Annual Review of Pathology-Mechanisms of Disease
- Breast cancer
- (2019) Nadia Harbeck et al. Nature Reviews Disease Primers
- Mechanisms of Chemotherapy Resistance in Triple-Negative Breast Cancer—How We Can Rise to the Challenge
- (2019) Nedeljković et al. Cells
- Atezolizumab plus nab-paclitaxel as first-line treatment for unresectable, locally advanced or metastatic triple-negative breast cancer (IMpassion130): updated efficacy results from a randomised, double-blind, placebo-controlled, phase 3 trial
- (2019) Peter Schmid et al. LANCET ONCOLOGY
- Smart cancer nanomedicine
- (2019) Roy van der Meel et al. Nature Nanotechnology
- Role of Reactive Oxygen Species in Cancer Progression: Molecular Mechanisms and Recent Advancements
- (2019) Vaishali Aggarwal et al. Biomolecules
- Could 3D models of cancer enhance drug screening?
- (2019) Virginia Brancato et al. BIOMATERIALS
- Grand challenges in nanomedicine
- (2019) Lin-Ping Wu et al. Materials Science & Engineering C-Materials for Biological Applications
- T lymphocytes facilitate brain metastasis of breast cancer by inducing Guanylate-Binding Protein 1 expression
- (2018) Dana A. M. Mustafa et al. ACTA NEUROPATHOLOGICA
- Tumor targeting via EPR: Strategies to enhance patient responses
- (2018) Susanne K. Golombek et al. ADVANCED DRUG DELIVERY REVIEWS
- Anticancer Activity Driven by Drug Linker Modification in a Polyglutamic Acid-Based Combination-Drug Conjugate
- (2018) Juan J. Arroyo-Crespo et al. ADVANCED FUNCTIONAL MATERIALS
- A novel 3D breast-cancer-on-chip platform for therapeutic evaluation of drug delivery systems
- (2018) Yongli Chen et al. ANALYTICA CHIMICA ACTA
- Humanized Mice as Unique Tools for Human-Specific Studies
- (2018) Kylie Su Mei Yong et al. ARCHIVUM IMMUNOLOGIAE ET THERAPIAE EXPERIMENTALIS
- Dual-targeting Wnt and uPA receptors using peptide conjugated ultra-small nanoparticle drug carriers inhibited cancer stem-cell phenotype in chemo-resistant breast cancer
- (2018) Jasmine Miller-Kleinhenz et al. BIOMATERIALS
- Doxorubicin resistance in breast cancer cells is mediated by extracellular matrix proteins
- (2018) Carrie J. Lovitt et al. BMC CANCER
- A Living Biobank of Breast Cancer Organoids Captures Disease Heterogeneity
- (2018) Norman Sachs et al. CELL
- Genetically engineered pigs as models for human disease
- (2018) Carolin Perleberg et al. Disease Models & Mechanisms
- The theranostic efficiency of tumor-specific, pH-responsive, peptide-modified, liposome-containing paclitaxel and superparamagnetic iron oxide nanoparticles
- (2018) Xiu-Chai Zheng et al. International Journal of Nanomedicine
- Co-delivery nanoparticle to overcome metastasis promoted by insufficient chemotherapy
- (2018) Qing Zhou et al. JOURNAL OF CONTROLLED RELEASE
- Nanoparticle transport pathways into tumors
- (2018) S. M. Moghimi et al. JOURNAL OF NANOPARTICLE RESEARCH
- Translational gaps in animal models of human infusion reactions to nanomedicines
- (2018) S Moein Moghimi et al. Nanomedicine
- Multicellular Tumor Spheroids (MCTS) as a 3D In Vitro Evaluation Tool of Nanoparticles
- (2018) Hongxu Lu et al. Small
- Zebrafish ( Danio rerio ) model as an early stage screening tool to study the biodistribution and toxicity profile of doxorubicin-loaded mixed micelles
- (2018) María Natalia Calienni et al. TOXICOLOGY AND APPLIED PHARMACOLOGY
- A Microvascularized Tumor-mimetic Platform for Assessing Anti-cancer Drug Efficacy
- (2018) Shantanu Pradhan et al. Scientific Reports
- Tumor microenvironment-targeted poly-L-glutamic acid-based combination conjugate for enhanced triple negative breast cancer treatment
- (2018) Juan J. Arroyo-Crespo et al. BIOMATERIALS
- Global cancer statistics 2018: GLOBOCAN estimates of incidence and mortality worldwide for 36 cancers in 185 countries
- (2018) Freddie Bray et al. CA-A CANCER JOURNAL FOR CLINICIANS
- Folate-receptor-targeted laser-activable poly(lactide-co-glycolic acid) nanoparticles loaded with paclitaxel/indocyanine green for photoacoustic/ultrasound imaging and chemo/photothermal therapy
- (2018) Fengqiu Liu et al. International Journal of Nanomedicine
- Advantages of patient-derived orthotopic mouse models and genetic reporters for developing fluorescence-guided surgery
- (2018) Thinzar M Lwin et al. JOURNAL OF SURGICAL ONCOLOGY
- Biomimetic nanoflowers by self-assembly of nanozymes to induce intracellular oxidative damage against hypoxic tumors
- (2018) Zhenzhen Wang et al. Nature Communications
- 3D tumor spheroids as in vitro models to mimic in vivo human solid tumors resistance to therapeutic drugs
- (2018) Ana S. Nunes et al. BIOTECHNOLOGY AND BIOENGINEERING
- Chemotherapy resistance and stemness in mitotically quiescent human breast cancer cells identified by fluorescent dye retention
- (2018) Lewis A. Quayle et al. CLINICAL & EXPERIMENTAL METASTASIS
- Intraductal patient-derived xenografts of estrogen receptor α-positive breast cancer recapitulate the histopathological spectrum and metastatic potential of human lesions
- (2018) Maryse Fiche et al. JOURNAL OF PATHOLOGY
- Insight into Cellular Uptake and Intracellular Trafficking of Nanoparticles
- (2018) Parisa Foroozandeh et al. Nanoscale Research Letters
- Roadmap and strategy for overcoming infusion reactions to nanomedicines
- (2018) Janos Szebeni et al. Nature Nanotechnology
- Trastuzumab Emtansine for Residual Invasive HER2-Positive Breast Cancer
- (2018) Gunter von Minckwitz et al. NEW ENGLAND JOURNAL OF MEDICINE
- Mouse Models for Cancer Immunotherapy Research
- (2018) Brian Olson et al. Cancer Discovery
- Homophilic CD44 Interactions Mediate Tumor Cell Aggregation and Polyclonal Metastasis in Patient-Derived Breast Cancer Models
- (2018) Xia Liu et al. Cancer Discovery
- 3D Bioprinting of Breast Cancer Models for Drug Resistance Study
- (2018) Ying Wang et al. ACS Biomaterials-Science & Engineering
- Atezolizumab Plus nab-Paclitaxel in the Treatment of Metastatic Triple-Negative Breast Cancer With 2-Year Survival Follow-up
- (2018) Sylvia Adams et al. JAMA Oncology
- How to design preclinical studies in nanomedicine and cell therapy to maximize the prospects of clinical translation
- (2018) John P. A. Ioannidis et al. Nature Biomedical Engineering
- Risk Factors and Preventions of Breast Cancer
- (2017) Yi-Sheng Sun et al. International Journal of Biological Sciences
- Nanomedicine applications in the treatment of breast cancer: current state of the art
- (2017) Di Wu et al. International Journal of Nanomedicine
- Effects of major parameters of nanoparticles on their physical and chemical properties and recent application of nanodrug delivery system in targeted chemotherapy
- (2017) Jing Zhang et al. International Journal of Nanomedicine
- Preclinical development of drug delivery systems for paclitaxel-based cancer chemotherapy
- (2017) Feihu Wang et al. JOURNAL OF CONTROLLED RELEASE
- Advances in multicellular spheroids formation
- (2017) X. Cui et al. Journal of the Royal Society Interface
- Trastuzumab emtansine versus capecitabine plus lapatinib in patients with previously treated HER2-positive advanced breast cancer (EMILIA): a descriptive analysis of final overall survival results from a randomised, open-label, phase 3 trial
- (2017) Véronique Diéras et al. LANCET ONCOLOGY
- Profiling the relationship between tumor-associated macrophages and pharmacokinetics of liposomal agents in preclinical murine models
- (2017) Andrew T. Lucas et al. Nanomedicine-Nanotechnology Biology and Medicine
- Multicellular tumor spheroids: a relevant 3D model for the in vitro preclinical investigation of polymer nanomedicines
- (2017) Gianpiero Lazzari et al. Polymer Chemistry
- In vitro microfluidic models of tumor microenvironment to screen transport of drugs and nanoparticles
- (2017) Altug Ozcelikkale et al. Wiley Interdisciplinary Reviews-Nanomedicine and Nanobiotechnology
- Inbred or Outbred? Genetic Diversity in Laboratory Rodent Colonies
- (2017) Thomas D. Brekke et al. G3-Genes Genomes Genetics
- Breast Cancer Cell Line Classification and Its Relevance with Breast Tumor Subtyping
- (2017) Xiaofeng Dai et al. Journal of Cancer
- Nanoparticle Interactions with the Immune System: Clinical Implications for Liposome-Based Cancer Chemotherapy
- (2017) Ninh M. La-Beck et al. Frontiers in Immunology
- The acidic tumor microenvironment: a target for smart cancer nano-theranostics
- (2017) Liangzhu Feng et al. National Science Review
- A novel nanopolymer based tumor targeted delivery system for paclitaxel
- (2017) A. T. Singh et al. JOURNAL OF CLINICAL ONCOLOGY
- PD-L1 Detection in Tumors Using [64Cu]Atezolizumab with PET
- (2016) Wojciech G. Lesniak et al. BIOCONJUGATE CHEMISTRY
- Investigating the effect of tumor vascularization on magnetic targeting in vivo using retrospective design of experiment
- (2016) Kuo-Ching Mei et al. BIOMATERIALS
- SWOG S0800 (NCI CDR0000636131): addition of bevacizumab to neoadjuvant nab-paclitaxel with dose-dense doxorubicin and cyclophosphamide improves pathologic complete response (pCR) rates in inflammatory or locally advanced breast cancer
- (2016) Z. A. Nahleh et al. BREAST CANCER RESEARCH AND TREATMENT
- Patient-derived xenograft (PDX) models in basic and translational breast cancer research
- (2016) Lacey E. Dobrolecki et al. CANCER AND METASTASIS REVIEWS
- A Preclinical Model for ERα-Positive Breast Cancer Points to the Epithelial Microenvironment as Determinant of Luminal Phenotype and Hormone Response
- (2016) George Sflomos et al. CANCER CELL
- Relevant Physicochemical Descriptors of “Soft Nanomedicines” to Bypass Biological Barriers
- (2016) Amaya Nino-Pariente et al. CURRENT PHARMACEUTICAL DESIGN
- Genetically engineered mouse models in oncology research and cancer medicine
- (2016) Kelly Kersten et al. EMBO Molecular Medicine
- Nanoparticles for imaging and treatment of metastatic breast cancer
- (2016) Qingxin Mu et al. Expert Opinion on Drug Delivery
- Treatment of natural mammary gland tumors in canines and felines using gold nanorods-assisted plasmonic photothermal therapy to induce tumor apoptosis
- (2016) Mostafa A. El-Sayed et al. International Journal of Nanomedicine
- Patient-derived Mammosphere and Xenograft Tumour Initiation Correlates with Progression to Metastasis
- (2016) Rachel Eyre et al. JOURNAL OF MAMMARY GLAND BIOLOGY AND NEOPLASIA
- Common swine models of cardiovascular disease for research and training
- (2016) Verónica Crisóstomo et al. LAB ANIMAL
- The cell fate: senescence or quiescence
- (2016) Menderes Yusuf Terzi et al. MOLECULAR BIOLOGY REPORTS
- Nanotechnology-Based Drug Delivery Systems for Photodynamic Therapy of Cancer: A Review
- (2016) Giovana Calixto et al. MOLECULES
- Docetaxel-Loaded PLGA Nanoparticles Improve Efficacy in Taxane-Resistant Triple-Negative Breast Cancer
- (2016) Charles J. Bowerman et al. NANO LETTERS
- Iron oxide nanoparticles inhibit tumour growth by inducing pro-inflammatory macrophage polarization in tumour tissues
- (2016) Saeid Zanganeh et al. Nature Nanotechnology
- Pigs as models of human cancers
- (2016) Tatiana Flisikowska et al. THERIOGENOLOGY
- Current understanding of interactions between nanoparticles and the immune system
- (2016) Marina A. Dobrovolskaia et al. TOXICOLOGY AND APPLIED PHARMACOLOGY
- Dogs as a Model for Cancer
- (2016) Heather L. Gardner et al. Annual Review of Animal Biosciences
- Engineered Swine Models of Cancer
- (2016) Adrienne L. Watson et al. Frontiers in Genetics
- Analysis of nanoparticle delivery to tumours
- (2016) Stefan Wilhelm et al. Nature Reviews Materials
- Canine cancer immunotherapy studies: linking mouse and human
- (2016) Jiwon S. Park et al. Journal for ImmunoTherapy of Cancer
- NSG Mice Provide a Better Spontaneous Model of Breast Cancer Metastasis than Athymic (Nude) Mice
- (2016) Madhavi Puchalapalli et al. PLoS One
- Toward a full understanding of the EPR effect in primary and metastatic tumors as well as issues related to its heterogeneity
- (2015) Hiroshi Maeda ADVANCED DRUG DELIVERY REVIEWS
- Complete regression of breast tumour with a single dose of docetaxel-entrapped core-cross-linked polymeric micelles
- (2015) Qizhi Hu et al. BIOMATERIALS
- Recommendations for Benchmarking Preclinical Studies of Nanomedicines
- (2015) C. M. Dawidczyk et al. CANCER RESEARCH
- A Review of Paclitaxel and Novel Formulations Including Those Suitable for Use in Dogs
- (2015) C. Khanna et al. JOURNAL OF VETERINARY INTERNAL MEDICINE
- Nanomedicine of anastrozole for breast cancer: Physicochemical evaluation, in vitro cytotoxicity on BT-549 and MCF-7 cell lines and preclinical study on rat model
- (2015) Gopal Venkatesh Shavi et al. LIFE SCIENCES
- Pharmacologic Sensitivity of Paclitaxel to Its Delivery Vehicles Drives Distinct Clinical Outcomes of Paclitaxel Formulations
- (2015) Yan Li et al. MOLECULAR PHARMACEUTICS
- 3D tumor tissue analogs and their orthotopic implants for understanding tumor-targeting of microenvironment-responsive nanosized chemotherapy and radiation
- (2015) Pallavi Sethi et al. Nanomedicine-Nanotechnology Biology and Medicine
- Role of the Tumor Microenvironment in Breast Cancer
- (2015) Savas D. Soysal et al. PATHOBIOLOGY
- Alternatives to animal testing: A review
- (2015) Sonali K. Doke et al. SAUDI PHARMACEUTICAL JOURNAL
- A bladder cancer microenvironment simulation system based on a microfluidic co-culture model
- (2015) Peng-fei Liu et al. Oncotarget
- A porcine model system of BRCA1 driven breast cancer
- (2015) Howard Donninger et al. Frontiers in Genetics
- Dissecting the Molecular Mechanism of Apoptosis during Photothermal Therapy Using Gold Nanoprisms
- (2014) Marta Pérez-Hernández et al. ACS Nano
- Drug discovery through stem cell-based organoid models
- (2014) Adrian Ranga et al. ADVANCED DRUG DELIVERY REVIEWS
- Three-Dimensional Cell Culture Systems and Their Applications in Drug Discovery and Cell-Based Biosensors
- (2014) Rasheena Edmondson et al. ASSAY AND DRUG DEVELOPMENT TECHNOLOGIES
- Nanoparticle toxicity assessment using an in vitro 3-D kidney organoid culture model
- (2014) Anna I. Astashkina et al. BIOMATERIALS
- Effects of Tumor Microenvironment Heterogeneity on Nanoparticle Disposition and Efficacy in Breast Cancer Tumor Models
- (2014) G. Song et al. CLINICAL CANCER RESEARCH
- Naturally Occurring Cancers in Dogs: Insights for Translational Genetics and Medicine
- (2014) C. E. Alvarez ILAR JOURNAL
- State-of-the-art in design rules for drug delivery platforms: Lessons learned from FDA-approved nanomedicines
- (2014) Charlene M. Dawidczyk et al. JOURNAL OF CONTROLLED RELEASE
- Challenges associated with penetration of nanoparticles across cell and tissue barriers: A review of current status and future prospects
- (2014) Sutapa Barua et al. Nano Today
- Animal models and therapeutic molecular targets of cancer: utility and limitations
- (2014) Maria Cekanova et al. Drug Design Development and Therapy
- PD-L1 Expression Correlates with Tumor-Infiltrating Lymphocytes and Response to Neoadjuvant Chemotherapy in Breast Cancer
- (2014) H. Wimberly et al. Cancer Immunology Research
- PD-L1 Expression in Triple-Negative Breast Cancer
- (2014) E. A. Mittendorf et al. Cancer Immunology Research
- Assessment of Juvenile Pigs to Serve as Human Pediatric Surrogates for Preclinical Formulation Pharmacokinetic Testing
- (2013) Wyatt J. Roth et al. AAPS Journal
- Nanomedicine therapeutic approaches to overcome cancer drug resistance
- (2013) Janet L. Markman et al. ADVANCED DRUG DELIVERY REVIEWS
- Change in the microenvironment of breast cancer studied by FTIR imaging
- (2013) S. Kumar et al. ANALYST
- Genetically engineered mouse models of cancer reveal new insights about the antitumor immune response
- (2013) Michel DuPage et al. CURRENT OPINION IN IMMUNOLOGY
- Nanoparticle clearance is governed by Th1/Th2 immunity and strain background
- (2013) Stephen W. Jones et al. JOURNAL OF CLINICAL INVESTIGATION
- Biodegradable polymeric micelle-encapsulated quercetin suppresses tumor growth and metastasis in both transgenic zebrafish and mouse models
- (2013) Qinjie Wu et al. Nanoscale
- Tumour heterogeneity in the clinic
- (2013) Philippe L. Bedard et al. NATURE
- Pharmacokinetics and Efficacy of PEGylated Liposomal Doxorubicin in an Intracranial Model of Breast Cancer
- (2013) Carey K. Anders et al. PLoS One
- Evaluation of Nanoparticle Uptake in Co-culture Cancer Models
- (2013) Elisabete C. Costa et al. PLoS One
- Blood vessel hyperpermeability and pathophysiology in human tumour xenograft models of breast cancer: a comparison of ectopic and orthotopic tumours
- (2012) Karyn S Ho et al. BMC CANCER
- Liposomal paclitaxel formulations
- (2012) Štěpán Koudelka et al. JOURNAL OF CONTROLLED RELEASE
- Doxil® — The first FDA-approved nano-drug: Lessons learned
- (2012) Yechezkel (Chezy) Barenholz JOURNAL OF CONTROLLED RELEASE
- Trastuzumab Emtansine for HER2-Positive Advanced Breast Cancer
- (2012) Sunil Verma et al. NEW ENGLAND JOURNAL OF MEDICINE
- Zebrafish Models for Human Cancer
- (2012) H. R. Shive VETERINARY PATHOLOGY
- VIP-targeted cytotoxic nanomedicine for breast cancer
- (2012) Aparna Dagar et al. Drug Delivery and Translational Research
- A Functional Role for Tumor Cell Heterogeneity in a Mouse Model of Small Cell Lung Cancer
- (2011) Joaquim Calbo et al. CANCER CELL
- Tumor Metastasis: Molecular Insights and Evolving Paradigms
- (2011) Scott Valastyan et al. CELL
- Adverse drug reaction profile of nanoparticle versus conventional formulation of paclitaxel: An observational study
- (2011) Avijit Hazra et al. INDIAN JOURNAL OF PHARMACOLOGY
- Nanotherapeutics in angiogenesis: synthesis and in vivo assessment of drug efficacy and biocompatibility in zebrafish embryos
- (2011) Jinping Cheng et al. International Journal of Nanomedicine
- Nanomedicine(s) under the Microscope
- (2011) Ruth Duncan et al. MOLECULAR PHARMACEUTICS
- Tumor grafts derived from women with breast cancer authentically reflect tumor pathology, growth, metastasis and disease outcomes
- (2011) Yoko S DeRose et al. NATURE MEDICINE
- Dog models of naturally occurring cancer
- (2011) Jennie L. Rowell et al. TRENDS IN MOLECULAR MEDICINE
- Pulsed Ultrasound Enhances Nanoparticle Penetration into Breast Cancer Spheroids
- (2010) Stephanie J. Grainger et al. MOLECULAR PHARMACEUTICS
- Targeting nanoparticles to cancer
- (2010) M. Wang et al. PHARMACOLOGICAL RESEARCH
- LRP6 overexpression defines a class of breast cancer subtype and is a target for therapy
- (2010) C.-C. Liu et al. PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA
- Phase I pharmacokinetic study of a weekly liposomal paclitaxel formulation (Genexol®-PM) in patients with solid tumors
- (2009) W. T. Lim et al. ANNALS OF ONCOLOGY
- Effects of Branching Architecture and Linker on the Activity of Hyperbranched Polymer−Drug Conjugates
- (2009) Omathanu Perumal et al. BIOCONJUGATE CHEMISTRY
- A Novel Lung Metastasis Signature Links Wnt Signaling with Cancer Cell Self-Renewal and Epithelial-Mesenchymal Transition in Basal-like Breast Cancer
- (2009) Theresa A. DiMeo et al. CANCER RESEARCH
- Phase II studies of polymer-doxorubicin (PK1, FCE28068) in the treatment of breast, lung and colorectal cancer
- (2009) Seymour INTERNATIONAL JOURNAL OF ONCOLOGY
- N-methylnitrosourea Induced Breast Cancer in Rat, the Histopathology of the Resulting Tumours and its Drawbacks as a Model
- (2009) M. Perše et al. PATHOLOGY & ONCOLOGY RESEARCH
- A clinical study on the premedication of paclitaxel liposome in the treatment of solid tumors
- (2008) Qian Zhang et al. BIOMEDICINE & PHARMACOTHERAPY
- Randomized Crossover Pharmacokinetic Study of Solvent-Based Paclitaxel and nab-Paclitaxel
- (2008) E. R. Gardner et al. CLINICAL CANCER RESEARCH
- Implications of the Cancer Stem-Cell Hypothesis for Breast Cancer Prevention and Therapy
- (2008) Madhuri Kakarala et al. JOURNAL OF CLINICAL ONCOLOGY
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