标题
Non-viral Vectors in Gene Therapy: Recent Development, Challenges, and Prospects
作者
关键词
-
出版物
AAPS Journal
Volume 23, Issue 4, Pages -
出版商
Springer Science and Business Media LLC
发表日期
2021-06-02
DOI
10.1208/s12248-021-00608-7
参考文献
相关参考文献
注意：仅列出部分参考文献，下载原文获取全部文献信息。- Lipophilic Peptide Dendrimers for Delivery of Splice-Switching Oligonucleotides
- (2021) Haneen Daralnakhla et al. Pharmaceutics
- Combinatorial Synthesis of a Lipidoid Library by Thiolactone Chemistry: In Vitro Screening and In Vivo Validation for siRNA Delivery
- (2020) Mijanur R. Molla et al. BIOCONJUGATE CHEMISTRY
- Study on the cellular internalization mechanisms and in vivo anti-bone metastasis prostate cancer efficiency of the peptide T7-modified polypeptide nanoparticles
- (2020) Yongwei Gu et al. DRUG DELIVERY
- Self-Assembled Nanoparticles Prepared from Low-Molecular-Weight PEI and Low-Generation PAMAM for EGFRvIII-Chimeric Antigen Receptor Gene Loading and T-Cell Transient Modification
- (2020) Qianru Yu et al. International Journal of Nanomedicine
- Poly(1-vinylimidazole) polyplexes as novel therapeutic gene carriers for lung cancer therapy
- (2020) Gayathri Kandasamy et al. Beilstein Journal of Nanotechnology
- Enhance transgene responses through improving cellular uptake and intracellular trafficking by bio-inspired non-viral vectors
- (2020) Xi-Xi Ma et al. JOURNAL OF NANOBIOTECHNOLOGY
- Breaking the selectivity-uptake trade-off of photoimmunoconjugates with nanoliposomal irinotecan for synergistic multi-tier cancer targeting
- (2020) Barry J. Liang et al. JOURNAL OF NANOBIOTECHNOLOGY
- Poly(lysine) Dendrimers Form Complexes with siRNA and Provide Its Efficient Uptake by Myeloid Cells: Model Studies for Therapeutic Nucleic Acid Delivery
- (2020) Michał Gorzkiewicz et al. INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES
- Biodegradable Polymers for Gene-Delivery Applications
- (2020) Chih-Kuang Chen et al. International Journal of Nanomedicine
- Arginine-Modified Polymers Facilitate Poly (Lactide-Co-Glycolide)-Based Nanoparticle Gene Delivery to Primary Human Astrocytes
- (2020) Jessica Proulx et al. International Journal of Nanomedicine
- Two Phase 3 Trials of Inclisiran in Patients with Elevated LDL Cholesterol
- (2020) Kausik K. Ray et al. NEW ENGLAND JOURNAL OF MEDICINE
- Efficiency of Cytosolic Delivery with Poly(β-amino ester) Nanoparticles is Dependent on the Effective pKa of the Polymer
- (2020) Denis Routkevitch et al. ACS Biomaterials-Science & Engineering
- Metallo-Liposomes of Ruthenium Used as Promising Vectors of Genetic Material
- (2020) José Antonio Lebrón et al. Pharmaceutics
- Particle-Size-Dependent Delivery of Antitumoral miRNA Using Targeted Mesoporous Silica Nanoparticles
- (2020) Lisa Haddick et al. Pharmaceutics
- Simultaneous Targeting of Two Master Regulators of Apoptosis with Dual-Action PNA– and DNA–Peptide Conjugates
- (2020) Yannic Altrichter et al. BIOCONJUGATE CHEMISTRY
- Non-viral mediated gene therapy in human cystic fibrosis airway epithelial cells recovers chloride channel functionality
- (2020) Myriam Sainz-Ramos et al. INTERNATIONAL JOURNAL OF PHARMACEUTICS
- Peptide-Based Nanoassemblies in Gene Therapy and Diagnosis: Paving the Way for Clinical Application
- (2020) Shabnam Tarvirdipour et al. MOLECULES
- Poly[oligo(ethylene glycol) methacrylate]-b-poly[(vinyl benzyl trimethylammonium chloride)] Based Multifunctional Hybrid Nanostructures Encapsulating Magnetic Nanoparticles and DNA
- (2020) Angeliki Chroni et al. Polymers
- Chitosan-Based Non-viral Gene and Drug Delivery Systems for Brain Cancer
- (2020) Montserrat Lara-Velazquez et al. Frontiers in Neurology
- Barriers and strategies of cationic liposomes for cancer gene therapy
- (2020) Chunyan Liu et al. Molecular Therapy-Methods & Clinical Development
- Cyclopropenium Nanoparticles and Gene Transfection in Cells
- (2020) Noam Y. Steinman et al. Pharmaceutics
- Aminoglycosides: From Antibiotics to Building Blocks for the Synthesis and Development of Gene Delivery Vehicles
- (2020) Maria Cristina Bellucci et al. Antibiotics-Basel
- Actively targeted gold nanoparticle composites improve behavior and cognitive impairment in Parkinson's disease mice
- (2020) Li Liu et al. Materials Science & Engineering C-Materials for Biological Applications
- Non-Viral Targeted Nucleic Acid Delivery: Apply Sequences for Optimization
- (2020) Yanfang Wang et al. Pharmaceutics
- Improvement of DNA Vector Delivery of DOTAP Lipoplexes by Short-Chain Aminolipids
- (2020) Jonas Buck et al. ACS Omega
- Cellular gene delivery via poly(hexamethylene biguanide)/pDNA self-assembled nanoparticles
- (2020) Alexandru Chivu et al. EUROPEAN JOURNAL OF PHARMACEUTICS AND BIOPHARMACEUTICS
- Safety and Efficacy of the BNT162b2 mRNA Covid-19 Vaccine
- (2020) Fernando P. Polack et al. NEW ENGLAND JOURNAL OF MEDICINE
- Lipid-Based DNA Therapeutics – Hallmarks of Non-Viral Gene Delivery
- (2019) Jonas Buck et al. ACS Nano
- RNAi therapeutic and its innovative biotechnological evolution
- (2019) Yuhua Weng et al. BIOTECHNOLOGY ADVANCES
- Polymeric Nanoparticles in Gene Therapy: New Avenues of Design and Optimization for Delivery Applications
- (2019) Raj Rai et al. Polymers
- Gene Therapy Leaves a Vicious Cycle
- (2019) Reena Goswami et al. Frontiers in Oncology
- Cumulative directional calcium gluing between phosphate and silicate: A facile, robust and biocompatible strategy for siRNA delivery by amine-free non-positive vector
- (2019) Eunshil Choi et al. BIOMATERIALS
- Recent Advances in Chitosan-Based Carriers for Gene Delivery
- (2019) Ye Cao et al. Marine Drugs
- Cellular Uptake and Distribution of Gemini Surfactant Nanoparticles Used as Gene Delivery Agents
- (2019) Wei Jin et al. AAPS Journal
- Size- and cell type-dependent cellular uptake, cytotoxicity and in vivo distribution of gold nanoparticles
- (2019) Qiyue Xia et al. International Journal of Nanomedicine
- In vivo activation of PEGylated long circulating lipid nanoparticle to achieve efficient siRNA delivery and target gene knock down in solid tumors
- (2019) Yumi Sasayama et al. JOURNAL OF CONTROLLED RELEASE
- Shifting Paradigms Revisited: Biotechnology and the Pharmaceutical Sciences
- (2019) Daan J.A. Crommelin et al. JOURNAL OF PHARMACEUTICAL SCIENCES
- Development and Clinical Translation of Approved Gene Therapy Products for Genetic Disorders
- (2019) Alireza Shahryari et al. Frontiers in Genetics
- Characterization of spray dried powders with nucleic acid-containing PEI nanoparticles
- (2019) Tobias W.M. Keil et al. EUROPEAN JOURNAL OF PHARMACEUTICS AND BIOPHARMACEUTICS
- Cancer gene therapy mediated by RALA/plasmid DNA vectors: Nitrogen to phosphate groups ratio (N/P) as a tool for tunable transfection efficiency and apoptosis
- (2019) A.R. Neves et al. COLLOIDS AND SURFACES B-BIOINTERFACES
- DNA fragment translocation through the lipid membrane assisted by carbon nanotube
- (2019) Lijun Liang et al. INTERNATIONAL JOURNAL OF PHARMACEUTICS
- Multi-functional self-assembled nanoparticles for pVEGF-shRNA loading and anti-tumor targeted therapy
- (2019) Sai Lu et al. INTERNATIONAL JOURNAL OF PHARMACEUTICS
- Transport of trans‐activator of transcription (TAT) peptide in tumour tissue model: evaluation of factors affecting the transport of TAT evidenced by flow cytometry
- (2019) Aziz Ur Rahman et al. JOURNAL OF PHARMACY AND PHARMACOLOGY
- Carboxylated branched poly(β-amino ester) nanoparticles enable robust cytosolic protein delivery and CRISPR-Cas9 gene editing
- (2019) Yuan Rui et al. Science Advances
- Sugar and Polymer Excipients Enhance Uptake and Splice-Switching Activity of Peptide-Dendrimer/Lipid/Oligonucleotide Formulations
- (2019) Osama Saher et al. Pharmaceutics
- Determining the effects of PEI adsorption on the permeability of 1,2-dipalmitoylphosphatidylcholine/bis(monoacylglycero)phosphate membranes under osmotic stress
- (2018) Scott R. Clark et al. Acta Biomaterialia
- Molecular and immunological toxic effects of nanoparticles
- (2018) Rajan Kumar Pandey et al. INTERNATIONAL JOURNAL OF BIOLOGICAL MACROMOLECULES
- Dexamethasone prodrugs as potent suppressors of the immunostimulatory effects of lipid nanoparticle formulations of nucleic acids
- (2018) Sam Chen et al. JOURNAL OF CONTROLLED RELEASE
- Double-slit photoelectron interference in strong-field ionization of the neon dimer
- (2018) Maksim Kunitski et al. Nature Communications
- Lipid Nanoparticle Systems for Enabling Gene Therapies
- (2017) Pieter R. Cullis et al. MOLECULAR THERAPY
- Size matters for in vitro gene delivery: investigating the relationships among complexation protocol, transfection medium, size and sedimentation
- (2017) Daniele Pezzoli et al. Scientific Reports
- The role of helper lipids in lipid nanoparticles (LNPs) designed for oligonucleotide delivery
- (2016) Xinwei Cheng et al. ADVANCED DRUG DELIVERY REVIEWS
- Synthesis, characterization, and self-assembly with plasmid DNA of a quaternary ammonium derivative of pectic galactan and its fluorescent labeling for bioimaging applications
- (2016) Ramesh Chintakunta et al. CARBOHYDRATE POLYMERS
- Graphene materials as 2D non-viral gene transfer vector platforms
- (2016) M Vincent et al. GENE THERAPY
- Non-viral gene therapy: Gains and challenges of non-invasive administration methods
- (2016) Marianna Foldvari et al. JOURNAL OF CONTROLLED RELEASE
- Exploring the Structural Properties of Positively Charged Peptide Dendrimers
- (2016) Luís C. S. Filipe et al. JOURNAL OF PHYSICAL CHEMISTRY B
- Utilising inorganic nanocarriers for gene delivery
- (2016) Xian Jun Loh et al. Biomaterials Science
- The transition from linear to highly branched poly( -amino ester)s: Branching matters for gene delivery
- (2016) D. Zhou et al. Science Advances
- Microbeads mediated oral plasmid DNA delivery using polymethacrylate vectors: an effectual groundwork for colorectal cancer
- (2014) Priyanka Bhatt et al. DRUG DELIVERY
- Spectrum and Mechanisms of Inflammasome Activation by Chitosan
- (2014) C. L. Bueter et al. JOURNAL OF IMMUNOLOGY
- Non-viral vectors for gene-based therapy
- (2014) Hao Yin et al. NATURE REVIEWS GENETICS
- Synthesis of Cationic Polylactides with Tunable Charge Densities as Nanocarriers for Effective Gene Delivery
- (2013) Charles H. Jones et al. MOLECULAR PHARMACEUTICS
- Overcoming Nonviral Gene Delivery Barriers: Perspective and Future
- (2013) Charles H. Jones et al. MOLECULAR PHARMACEUTICS
- Combinatorial Library of Lipidoids for In Vitro DNA Delivery
- (2011) Shuo Sun et al. BIOCONJUGATE CHEMISTRY
- Discovery of Cationic Polymers for Non-Viral Gene Delivery Using Combinatorial Approaches
- (2011) Sutapa Barua et al. COMBINATORIAL CHEMISTRY & HIGH THROUGHPUT SCREENING
- A combinatorial library of lipid-like materials for delivery of RNAi therapeutics
- (2008) Akin Akinc et al. NATURE BIOTECHNOLOGY
Find the ideal target journal for your manuscript
Explore over 38,000 international journals covering a vast array of academic fields.
SearchBecome a Peeref-certified reviewer
The Peeref Institute provides free reviewer training that teaches the core competencies of the academic peer review process.
Get Started