Heme activates platelets and exacerbates rhabdomyolysis-induced acute kidney injury via CLEC-2 and GPVI/FcRγ

Functional significance of the platelet immune receptors GPVI and CLEC-2

(2019) Julie Rayes et al.   JOURNAL OF CLINICAL INVESTIGATION

Mac‐1 triggers neutrophil DNA extracellular trap formation to Aspergillus fumigatus independently of PAD4 histone citrullination

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Platelets and cancer-associated thrombosis: focusing on the platelet activation receptor CLEC-2 and podoplanin

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Macrophage extracellular trap formation promoted by platelet activation is a key mediator of rhabdomyolysis-induced acute kidney injury

(2018) Koshu Okubo et al.   NATURE MEDICINE

The role of complement activation in rhabdomyolysis-induced acute kidney injury

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C-type lectin-like receptor 2 promotes hematogenous tumor metastasis and prothrombotic state in tumor-bearing mice

(2017) T. Shirai et al.   JOURNAL OF THROMBOSIS AND HAEMOSTASIS

Platelet CLEC-2: Roles Beyond Hemostasis

(2017) Nagaharu Tsukiji et al.   SEMINARS IN THROMBOSIS AND HEMOSTASIS

Leukocyte integrin Mac-1 regulates thrombosis via interaction with platelet GPIbα

(2017) Yunmei Wang et al.   Nature Communications

Vascular Smooth Muscle Cells Stimulate Platelets and Facilitate Thrombus Formation through Platelet CLEC-2: Implications in Atherothrombosis

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Specific Macrophage Subtypes Influence the Progression of Rhabdomyolysis-Induced Kidney Injury

(2014) J. Belliere et al.   JOURNAL OF THE AMERICAN SOCIETY OF NEPHROLOGY

Heme in pathophysiology: a matter of scavenging, metabolism and trafficking across cell membranes

(2014) Deborah Chiabrando et al.   Frontiers in Pharmacology

Acetaminophen inhibits hemoprotein-catalyzed lipid peroxidation and attenuates rhabdomyolysis-induced renal failure

(2010) O. Boutaud et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Novel interactions in platelet biology: CLEC-2/podoplanin and laminin/GPVI

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Rhabdomyolysis and Acute Kidney Injury

(2009) Xavier Bosch et al.   NEW ENGLAND JOURNAL OF MEDICINE