C-type lectin-like receptor 2 promotes hematogenous tumor metastasis and prothrombotic state in tumor-bearing mice

Podoplanin-positive periarteriolar stromal cells promote megakaryocyte growth and proplatelet formation in mice by CLEC-2

(2016) S. Tamura et al.   BLOOD

Targeted downregulation of platelet CLEC-2 occurs through Syk-independent internalization

(2015) V. Lorenz et al.   BLOOD

A Novel Direct Factor Xa Inhibitory Peptide with Anti-Platelet Aggregation Activity from Agkistrodon acutus Venom Hydrolysates

(2015) Meimei Chen et al.   Scientific Reports

Vascular Smooth Muscle Cells Stimulate Platelets and Facilitate Thrombus Formation through Platelet CLEC-2: Implications in Atherothrombosis

(2015) Osamu Inoue et al.   PLoS One

Podoplanin expression in cancer-associated fibroblasts predicts aggressive behavior in melanoma

(2014) Saori Kan et al.   JOURNAL OF CUTANEOUS PATHOLOGY

The CLEC-2–podoplanin axis controls the contractility of fibroblastic reticular cells and lymph node microarchitecture

(2014) Jillian L Astarita et al.   NATURE IMMUNOLOGY

Therapy for Cancer-Related Thromboembolism

(2014) Corinne Frere et al.   SEMINARS IN ONCOLOGY

Platelets Effects on Tumor Growth

(2014) Hadi A. Goubran et al.   SEMINARS IN ONCOLOGY

Immunohistochemical evaluation of tissue factor, fibrin/fibrinogen and D-dimers in canine gliomas

(2014) Cristian de la Fuente et al.   VETERINARY JOURNAL

Combined In Vivo Depletion of Glycoprotein VI and C-Type Lectin-Like Receptor 2 Severely Compromises Hemostasis and Abrogates Arterial Thrombosis in Mice

(2013) Markus Bender et al.   ARTERIOSCLEROSIS THROMBOSIS AND VASCULAR BIOLOGY

Holothurian Glycosaminoglycan Inhibits Metastasis and Thrombosis via Targeting of Nuclear Factor-κB/Tissue Factor/Factor Xa Pathway in Melanoma B16F10 Cells

(2013) Yang Zhao et al.   PLoS One

Interleukin-6 signaling pathway in targeted therapy for cancer

(2012) Yuqi Guo et al.   CANCER TREATMENT REVIEWS

Podoplanin-Rich Stromal Networks Induce Dendritic Cell Motility via Activation of the C-type Lectin Receptor CLEC-2

(2012) Sophie E. Acton et al.   IMMUNITY

Tumor-platelet interaction in solid tumors

(2012) Daniel Buergy et al.   INTERNATIONAL JOURNAL OF CANCER

Platelet Activation Receptor CLEC-2 Regulates Blood/Lymphatic Vessel Separation by Inhibiting Proliferation, Migration, and Tube Formation of Lymphatic Endothelial Cells

(2012) Makoto Osada et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Effect of daily aspirin on risk of cancer metastasis: a study of incident cancers during randomised controlled trials

(2012) Peter M Rothwell et al.   LANCET

Do circulating tumor cells play a role in coagulation and thrombosis?

(2012) Garth W. Tormoen et al.   Frontiers in Oncology

CLEC-2 signaling via Syk in myeloid cells can regulate inflammatory responses

(2011) Diego Mourão-Sá et al.   EUROPEAN JOURNAL OF IMMUNOLOGY

Novel platelet activation receptor CLEC-2: from discovery to prospects

(2011) K. SUZUKI-INOUE et al.   JOURNAL OF THROMBOSIS AND HAEMOSTASIS

Definition and classification of cancer cachexia: an international consensus

(2011) Kenneth Fearon et al.   LANCET ONCOLOGY

Essentialin VivoRoles of the C-type Lectin Receptor CLEC-2

(2010) Katsue Suzuki-Inoue et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

CLEC-2 is not required for platelet aggregation at arteriolar shear

(2010) C. E. HUGHES et al.   JOURNAL OF THROMBOSIS AND HAEMOSTASIS

CLEC-2 is an essential platelet-activating receptor in hemostasis and thrombosis

(2009) F. May et al.   BLOOD