Continuous MYD88 Activation Is Associated With Expansion and Then Transformation of IgM Differentiating Plasma Cells

Promoter methylation status of ASC/TMS1/PYCARD is associated with decreased overall survival and TNM status in patients with early stage non-small cell lung cancer (NSCLC)

(2020) Maja Šutić et al.   Translational Lung Cancer Research

LUBAC accelerates B-cell lymphomagenesis by conferring B cells resistance to genotoxic stress

(2020) Tomoyasu Jo et al.   BLOOD

NF-κB mediates lipopolysaccharide-induced alternative pre-mRNA splicing of MyD88 in mouse macrophages

(2020) Frank Fang-Yao Lee et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Adaptive T-cell immunity controls senescence-prone MyD88- or CARD11-mutant B-cell lymphomas

(2020) Maurice Reimann et al.   BLOOD

B-Cell-Specific Myd88 L252P Expression Causes a Premalignant Gammopathy Resembling IgM MGUS

(2020) Kristin Schmidt et al.   Frontiers in Immunology

Reproducing indolent B-cell lymphoma transformation with T-cell immunosuppression in LMP1/CD40-expressing mice

(2019) Christelle Vincent-Fabert et al.   Cellular & Molecular Immunology

How Recent Advances in Biology of Waldenström’s Macroglobulinemia May Affect Therapy Strategy

(2019) Marine Baron et al.   Current Oncology Reports

MyD88 hypermethylation mediated by DNMT1 is associated with LTA-induced inflammatory response in human odontoblast-like cells

(2019) Runsha Meng et al.   CELL AND TISSUE RESEARCH

Inflamed phenotype of splenic marginal zone B-cell lymphomas with expression of PD-L1 by intratumoral monocytes/macrophages and dendritic cells

(2019) Christelle Vincent-Fabert et al.   Cellular & Molecular Immunology

Pre-clinical blocking of PD-L1 molecule, which expression is down regulated by NF-κB, JAK1/JAK2 and BTK inhibitors, induces regression of activated B-cell lymphoma

(2019) Christelle Vincent-Fabert et al.   Cell Communication and Signaling

MYD88 in the driver’s seat of B-cell lymphomagenesis: from molecular mechanisms to clinical implications

(2019) Ruben A.L. de Groen et al.   HAEMATOLOGICA

Normal serum protein electrophoresis and mutated IGHV genes detect very slowly evolving chronic lymphocytic leukemia patients

(2018) Jasmine Chauzeix et al.   Cancer Medicine

c-Myc dysregulation is a co-transforming event for nuclear factor-κB activated B cells

(2017) Amandine David et al.   HAEMATOLOGICA

Bioinformatic analysis of gene expression and methylation regulation in glioblastoma

(2017) Wen Wang et al.   JOURNAL OF NEURO-ONCOLOGY

Clinical utility of recently identified diagnostic, prognostic, and predictive molecular biomarkers in mature B-cell neoplasms

(2017) Arantza Onaindia et al.   MODERN PATHOLOGY

c-Myc dysregulation is a co-transforming event for nuclear factor-κB activated B cells

(2017) Amandine David et al.   HAEMATOLOGICA

B-cell-specific conditional expression of Myd88p.L252P leads to the development of diffuse large B-cell lymphoma in mice

(2016) G. Knittel et al.   BLOOD

Transcriptome sequencing reveals a profile that corresponds to genomic variants in Waldenström macroglobulinemia

(2016) Zachary R. Hunter et al.   BLOOD

Treatment recommendations from the Eighth International Workshop on Waldenstroms Macroglobulinemia

(2016) V. Leblond et al.   BLOOD

Corrigendum: Long-lived antigen-induced IgM plasma cells demonstrate somatic mutations and contribute to long-term protection

(2016) Caitlin Bohannon et al.   Nature Communications

Genomic Landscape of CXCR4 Mutations in Waldenstro m Macroglobulinemia

(2015) S. Poulain et al.   CLINICAL CANCER RESEARCH

Consequences of the recurrentMYD88L265Psomatic mutation for B cell tolerance

(2014) James Q. Wang et al.   JOURNAL OF EXPERIMENTAL MEDICINE

Germinal center B cell maintenance and differentiation are controlled by distinct NF-κB transcription factor subunits

(2014) Nicole Heise et al.   JOURNAL OF EXPERIMENTAL MEDICINE

RelA and RelB cross-talk and function in Epstein–Barr virus transformed B cells

(2013) A Chanut et al.   LEUKEMIA

MYD88 L265P is a marker highly characteristic of, but not restricted to, Waldenström’s macroglobulinemia

(2013) C Jiménez et al.   LEUKEMIA

IGHV gene features and MYD88 L265P mutation separate the three marginal zone lymphoma entities and Waldenström macroglobulinemia/lymphoplasmacytic lymphomas

(2012) N Gachard et al.   LEUKEMIA

MYD88 L265P Somatic Mutation in Waldenström's Macroglobulinemia

(2012) Steven P. Treon et al.   NEW ENGLAND JOURNAL OF MEDICINE

FLASH: fast length adjustment of short reads to improve genome assemblies

(2011) T. Magoc et al.   BIOINFORMATICS

The isotype of the BCR as a surrogate for the GCB and ABC molecular subtypes in diffuse large B-cell lymphoma

(2011) P Ruminy et al.   LEUKEMIA

Specific deletion of TRAF3 in B lymphocytes leads to B-lymphoma development in mice

(2011) C R Moore et al.   LEUKEMIA

Genomic deletion of the whole IgH 3' regulatory region (hs3a, hs1,2, hs3b, and hs4) dramatically affects class switch recombination and Ig secretion to all isotypes

(2010) C. Vincent-Fabert et al.   BLOOD

Oncogenically active MYD88 mutations in human lymphoma

(2010) Vu N. Ngo et al.   NATURE

E -BCL10 mice exhibit constitutive activation of both canonical and noncanonical NF- B pathways generating marginal zone (MZ) B-cell expansion as a precursor to splenic MZ lymphoma

(2009) Z. Li et al.   BLOOD

Comparative analysis of oncogenic properties and nuclear factor- B activity of latent membrane protein 1 natural variants from Hodgkin's lymphoma's Reed-Sternberg cells and normal B-lymphocytes

(2009) N. Faumont et al.   HAEMATOLOGICA

c-Myc and Rel/NF- B Are the Two Master Transcriptional Systems Activated in the Latency III Program of Epstein-Barr Virus-Immortalized B Cells

(2009) N. Faumont et al.   JOURNAL OF VIROLOGY

CD93 is required for maintenance of antibody secretion and persistence of plasma cells in the bone marrow niche

(2009) S. Chevrier et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Constitutive CD40 signaling in B cells selectively activates the noncanonical NF-κB pathway and promotes lymphomagenesis

(2008) Cornelia Hömig-Hölzel et al.   JOURNAL OF EXPERIMENTAL MEDICINE