Differences in interactions between transmembrane domains tune the activation of metabotropic glutamate receptors
出版年份 2021 全文链接
标题
Differences in interactions between transmembrane domains tune the activation of metabotropic glutamate receptors
作者
关键词
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出版物
eLife
Volume 10, Issue -, Pages -
出版商
eLife Sciences Publications, Ltd
发表日期
2021-04-21
DOI
10.7554/elife.67027
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注意:仅列出部分参考文献,下载原文获取全部文献信息。- Conformational rearrangement during activation of a metabotropic glutamate receptor
- (2021) Brandon Wey-Hung Liauw et al. Nature Chemical Biology
- Cryo-EM structures of inactive and active GABAB receptor
- (2020) Chunyou Mao et al. CELL RESEARCH
- Structural basis of the activation of a metabotropic GABA receptor
- (2020) Hamidreza Shaye et al. NATURE
- Structure of human GABAB receptor in an inactive state
- (2020) Jinseo Park et al. NATURE
- Structures of metabotropic GABAB receptor
- (2020) Makaía M. Papasergi-Scott et al. NATURE
- Single-molecule analysis reveals agonist-specific dimer formation of µ-opioid receptors
- (2020) Jan Möller et al. Nature Chemical Biology
- A general method to optimize and functionalize red-shifted rhodamine dyes
- (2020) Jonathan B. Grimm et al. NATURE METHODS
- Defining the Homo- and Heterodimerization Propensities of Metabotropic Glutamate Receptors
- (2020) Joon Lee et al. Cell Reports
- Structural and Biophysical Mechanisms of Class C G Protein-Coupled Receptor Function
- (2020) Amr Ellaithy et al. TRENDS IN BIOCHEMICAL SCIENCES
- Symmetric signal transduction and negative allosteric modulation of heterodimeric mGlu1/5 receptors
- (2020) Ruth C. Werthmann et al. NEUROPHARMACOLOGY
- Shaky ground - The nature of metastable GPCR signalling complexes
- (2019) Rory Sleno et al. NEUROPHARMACOLOGY
- Structural insights into the activation of metabotropic glutamate receptors
- (2019) Antoine Koehl et al. NATURE
- Stepwise activation of a class C GPCR begins with millisecond dimer rearrangement
- (2019) Eugene O. Grushevskyi et al. PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA
- Conformational dynamics between transmembrane domains and allosteric modulation of a metabotropic glutamate receptor
- (2019) Vanessa A Gutzeit et al. eLife
- Conformational pathway provides unique sensitivity to a synaptic mGluR
- (2019) Chris H. Habrian et al. Nature Communications
- Glycine Perturbs Local and Global Conformational Flexibility of a Transmembrane Helix
- (2018) Philipp Högel et al. BIOCHEMISTRY
- Structure-Based Optimization Strategies for G Protein-Coupled Receptor (GPCR) Allosteric Modulators: A Case Study from Analyses of New Metabotropic Glutamate Receptor 5 (mGlu5) X-ray Structures
- (2018) John A. Christopher et al. JOURNAL OF MEDICINAL CHEMISTRY
- How to run molecular dynamics simulations on electrospray droplets and gas phase proteins: Basic guidelines and selected applications
- (2018) Lars Konermann et al. METHODS
- Differential Pharmacology and Binding of mGlu2Receptor Allosteric Modulators
- (2018) Daniel E. O’Brien et al. MOLECULAR PHARMACOLOGY
- Glutamatergic Signaling in the Central Nervous System: Ionotropic and Metabotropic Receptors in Concert
- (2018) Andreas Reiner et al. NEURON
- CCR5 adopts three homodimeric conformations that control cell surface delivery
- (2018) Jun Jin et al. Science Signaling
- Dynamic tuneable G protein-coupled receptor monomer-dimer populations
- (2018) Patricia M. Dijkman et al. Nature Communications
- Molecular details of dimerization kinetics reveal negligible populations of transient µ-opioid receptor homodimers at physiological concentrations
- (2018) Derya Meral et al. Scientific Reports
- CCR5 adopts three homodimeric conformations that control cell surface delivery
- (2018) Jun Jin et al. Science Signaling
- Chloride ions stabilize the glutamate-induced active state of the metabotropic glutamate receptor 3
- (2018) Amélie S. Tora et al. NEUROPHARMACOLOGY
- Oligomerization of a G protein-coupled receptor in neurons controlled by its structural dynamics
- (2018) Thor C. Møller et al. Scientific Reports
- GPCR homo-oligomerization
- (2018) Graeme Milligan et al. CURRENT OPINION IN CELL BIOLOGY
- Electronic tuning of self-healing fluorophores for live-cell and single-molecule imaging
- (2017) Qinsi Zheng et al. Chemical Science
- Receptor Quaternary Organization Explains G Protein-Coupled Receptor Family Structure
- (2017) James H. Felce et al. Cell Reports
- Allosteric control of an asymmetric transduction in a G protein-coupled receptor heterodimer
- (2017) Junke Liu et al. eLife
- Pharmacological evidence for a metabotropic glutamate receptor heterodimer in neuronal cells
- (2017) David Moreno Delgado et al. eLife
- Allosteric Modulation as a Unifying Mechanism for Receptor Function and Regulation
- (2016) Jean-Pierre Changeux et al. CELL
- Organization and functions of mGlu and GABAB receptor complexes
- (2016) Jean-Philippe Pin et al. NATURE
- Bright photoactivatable fluorophores for single-molecule imaging
- (2016) Jonathan B Grimm et al. NATURE METHODS
- Mechanism of Assembly and Cooperativity of Homomeric and Heteromeric Metabotropic Glutamate Receptors
- (2016) Joshua Levitz et al. NEURON
- Allosteric signaling through an mGlu2 and 5-HT2Aheteromeric receptor complex and its potential contribution to schizophrenia
- (2016) José L. Moreno et al. Science Signaling
- Allosteric signaling through an mGlu2 and 5-HT2Aheteromeric receptor complex and its potential contribution to schizophrenia
- (2016) José L. Moreno et al. Science Signaling
- Overlapping binding sites drive allosteric agonism and positive cooperativity in type 4 metabotropic glutamate receptors
- (2015) Xavier Rovira et al. FASEB JOURNAL
- Computational Lipidomics with insane: A Versatile Tool for Generating Custom Membranes for Molecular Simulations
- (2015) Tsjerk A. Wassenaar et al. Journal of Chemical Theory and Computation
- PyEMMA 2: A Software Package for Estimation, Validation, and Analysis of Markov Models
- (2015) Martin K. Scherer et al. Journal of Chemical Theory and Computation
- Fragment and Structure-Based Drug Discovery for a Class C GPCR: Discovery of the mGlu5 Negative Allosteric Modulator HTL14242 (3-Chloro-5-[6-(5-fluoropyridin-2-yl)pyrimidin-4-yl]benzonitrile)
- (2015) John A. Christopher et al. JOURNAL OF MEDICINAL CHEMISTRY
- Conformational dynamics of a class C G-protein-coupled receptor
- (2015) Reza Vafabakhsh et al. NATURE
- A general method to improve fluorophores for live-cell and single-molecule microscopy
- (2015) Jonathan B Grimm et al. NATURE METHODS
- Selective Actions of Novel Allosteric Modulators Reveal Functional Heteromers of Metabotropic Glutamate Receptors in the CNS
- (2014) S. Yin et al. JOURNAL OF NEUROSCIENCE
- Structure of class C GPCR metabotropic glutamate receptor 5 transmembrane domain
- (2014) Andrew S. Doré et al. NATURE
- Major ligand-induced rearrangement of the heptahelical domain interface in a GPCR dimer
- (2014) Li Xue et al. Nature Chemical Biology
- Structure of a Class C GPCR Metabotropic Glutamate Receptor 1 Bound to an Allosteric Modulator
- (2014) H. Wu et al. SCIENCE
- Fine tuning of sub-millisecond conformational dynamics controls metabotropic glutamate receptors agonist efficacy
- (2014) Linnea Olofsson et al. Nature Communications
- PLUMED 2: New feathers for an old bird
- (2013) Gareth A. Tribello et al. COMPUTER PHYSICS COMMUNICATIONS
- Illuminating the activation mechanisms and allosteric properties of metabotropic glutamate receptors
- (2013) E. Doumazane et al. PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA
- Fuzzy spectral clustering by PCCA+: application to Markov state models and data classification
- (2013) Susanna Röblitz et al. Advances in Data Analysis and Classification
- Glycines: Role in α-Helical Membrane Protein Structures and a Potential Indicator of Native Conformation
- (2012) Hao Dong et al. BIOCHEMISTRY
- Identification of Three Residues Essential for 5-Hydroxytryptamine 2A-Metabotropic Glutamate 2 (5-HT2A·mGlu2) Receptor Heteromerization and Its Psychoactive Behavioral Function
- (2012) José L. Moreno et al. JOURNAL OF BIOLOGICAL CHEMISTRY
- Improved Parameters for the Martini Coarse-Grained Protein Force Field
- (2012) Djurre H. de Jong et al. Journal of Chemical Theory and Computation
- Heterocomplex formation of 5-HT2A-mGlu2 and its relevance for cellular signaling cascades
- (2012) Hannah K. Delille et al. NEUROPHARMACOLOGY
- Distinct roles of metabotropic glutamate receptor dimerization in agonist activation and G-protein coupling
- (2012) D. El Moustaine et al. PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA
- Sequential Inter- and Intrasubunit Rearrangements During Activation of Dimeric Metabotropic Glutamate Receptor 1
- (2012) V. Hlavackova et al. Science Signaling
- Decoding the Signaling of a GPCR Heteromeric Complex Reveals a Unifying Mechanism of Action of Antipsychotic Drugs
- (2011) Miguel Fribourg et al. CELL
- Full characterization of GPCR monomer–dimer dynamic equilibrium by single molecule imaging
- (2011) Rinshi S. Kasai et al. JOURNAL OF CELL BIOLOGY
- Probing cellular protein complexes using single-molecule pull-down
- (2011) Ankur Jain et al. NATURE
- Interdomain movements in metabotropic glutamate receptor activation
- (2011) S. Huang et al. PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA
- A new approach to analyze cell surface protein complexes reveals specific heterodimeric metabotropic glutamate receptors
- (2010) Etienne Doumazane et al. FASEB JOURNAL
- Formation and dissociation of M1 muscarinic receptor dimers seen by total internal reflection fluorescence imaging of single molecules
- (2010) J. A. Hern et al. PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA
- Purification and Functional Reconstitution of Monomeric μ-Opioid Receptors
- (2009) Adam J. Kuszak et al. JOURNAL OF BIOLOGICAL CHEMISTRY
- Enzymatic assembly of DNA molecules up to several hundred kilobases
- (2009) Daniel G Gibson et al. NATURE METHODS
- Optical measurement of mGluR1 conformational changes reveals fast activation, slow deactivation, and sensitization
- (2009) P. Marcaggi et al. PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA
- HaloTag: A Novel Protein Labeling Technology for Cell Imaging and Protein Analysis
- (2008) Georgyi V. Los et al. ACS Chemical Biology
- Molecular dynamics simulation of confined fluids in isosurface-isothermal-isobaric ensemble
- (2008) Hossein Eslami et al. JOURNAL OF CHEMICAL PHYSICS
- Identification of a serotonin/glutamate receptor complex implicated in psychosis
- (2008) Javier González-Maeso et al. NATURE
- How and why do GPCRs dimerize?
- (2008) Vsevolod V. Gurevich et al. TRENDS IN PHARMACOLOGICAL SCIENCES
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