Inositol 1,4,5-trisphosphate 3-kinase B promotes Ca2+ mobilization and the inflammatory activity of dendritic cells

Single-Cell Analysis of Human Mononuclear Phagocytes Reveals Subset-Defining Markers and Identifies Circulating Inflammatory Dendritic Cells

(2019) Charles-Antoine Dutertre et al.   IMMUNITY

Calcineurin-mediated IL-2 production by CD11chighMHCII+ myeloid cells is crucial for intestinal immune homeostasis

(2018) Andrea Mencarelli et al.   Nature Communications

The calcineurin-NFAT axis contributes to host defense during Pseudomonas aeruginosa lung infection

(2017) Zheng Pang et al.   JOURNAL OF LEUKOCYTE BIOLOGY

Single-cell RNA-seq reveals new types of human blood dendritic cells, monocytes, and progenitors

(2017) Alexandra-Chloé Villani et al.   SCIENCE

Drug nanocarriers to treat autoimmunity and chronic inflammatory diseases

(2017) Davide Prosperi et al.   SEMINARS IN IMMUNOLOGY

Inflammatory role of dendritic cells in Amyotrophic Lateral Sclerosis revealed by an analysis of patients’ peripheral blood

(2017) Michela Rusconi et al.   Scientific Reports

Impaired calcineurin signaling in myeloid cells results in downregulation of pentraxin-3 and increased susceptibility to aspergillosis

(2016) T Zelante et al.   Mucosal Immunology

Ion Channels in Innate and Adaptive Immunity

(2015) Stefan Feske et al.   Annual Review of Immunology

The type 2 inositol 1,4,5-trisphosphate receptor, emerging functions for an intriguing Ca2+-release channel

(2015) Tamara Vervloessem et al.   BIOCHIMICA ET BIOPHYSICA ACTA-MOLECULAR CELL RESEARCH

Phagocytosis-dependent activation of a TLR9-BTK-calcineurin-NFAT pathway co-ordinates innate immunity to Aspergillus fumigatus

(2015) S. Herbst et al.   EMBO Molecular Medicine

GM-CSF Mouse Bone Marrow Cultures Comprise a Heterogeneous Population of CD11c+MHCII+ Macrophages and Dendritic Cells

(2015) Julie Helft et al.   IMMUNITY

Ca2+Signaling but Not Store-Operated Ca2+Entry Is Required for the Function of Macrophages and Dendritic Cells

(2015) Martin Vaeth et al.   JOURNAL OF IMMUNOLOGY

Store-Operated Calcium Channels

(2015) Murali Prakriya et al.   PHYSIOLOGICAL REVIEWS

Inhibition of the Inositol Kinase Itpkb Augments Calcium Signaling in Lymphocytes and Reveals a Novel Strategy to Treat Autoimmune Disease

(2015) Andrew T. Miller et al.   PLoS One

Calcineurin/NFAT signaling and innate host defence: a role for NOD1-mediated phagocytic functions

(2014) Alain Vandewalle et al.   Cell Communication and Signaling

Assessing the In Vivo Targeting Efficiency of Multifunctional Nanoconstructs Bearing Antibody-Derived Ligands

(2013) Luisa Fiandra et al.   ACS Nano

Orientation-Controlled Conjugation of Haloalkane Dehalogenase Fused Homing Peptides to Multifunctional Nanoparticles for the Specific Recognition of Cancer Cells

(2013) Serena Mazzucchelli et al.   ANGEWANDTE CHEMIE-INTERNATIONAL EDITION

Orai1-NFAT signalling pathway triggered by T cell receptor stimulation

(2013) Sonal Srikanth et al.   MOLECULES AND CELLS

Regulation and dysregulation of innate immunity by NFAT signaling downstream of pattern recognition receptors (PRRs)

(2012) Ivan Zanoni et al.   EUROPEAN JOURNAL OF IMMUNOLOGY

CD14 and NFAT mediate lipopolysaccharide-induced skin edema formation in mice

(2012) Ivan Zanoni et al.   JOURNAL OF CLINICAL INVESTIGATION

Regulation of lymphocyte function by ORAI and STIM proteins in infection and autoimmunity

(2012) Patrick J. Shaw et al.   JOURNAL OF PHYSIOLOGY-LONDON

Site-Specific Conjugation of ScFvs Antibodies to Nanoparticles by Bioorthogonal Strain-Promoted Alkyne-Nitrone Cycloaddition

(2011) Miriam Colombo et al.   ANGEWANDTE CHEMIE-INTERNATIONAL EDITION

Similarities and differences of innate immune responses elicited by smooth and rough LPS

(2011) Ivan Zanoni et al.   IMMUNOLOGY LETTERS

The kinase LRRK2 is a regulator of the transcription factor NFAT that modulates the severity of inflammatory bowel disease

(2011) Zhihua Liu et al.   NATURE IMMUNOLOGY

TNF activates calcium-nuclear factor of activated T cells (NFAT)c1 signaling pathways in human macrophages

(2011) A. Yarilina et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Deciphering the complexity of Toll-like receptor signaling

(2010) Renato Ostuni et al.   CELLULAR AND MOLECULAR LIFE SCIENCES

Inositol 1,4,5-trisphosphate 3-kinase B controls survival and prevents anergy in B cells

(2010) Yoann Maréchal et al.   IMMUNOBIOLOGY

Calcineurin regulates innate antifungal immunity in neutrophils

(2010) Matthew B. Greenblatt et al.   JOURNAL OF EXPERIMENTAL MEDICINE

An In Vivo Fluorescent Sensor Reveals Intracellular Ins(1,3,4,5)P4Dynamics in Single Cells

(2009) Reiko Sakaguchi et al.   ANGEWANDTE CHEMIE-INTERNATIONAL EDITION

Dectin-2 is a Syk-coupled pattern recognition receptor crucial for Th17 responses to fungal infection

(2009) Matthew J. Robinson et al.   JOURNAL OF EXPERIMENTAL MEDICINE

Inositol 1,4,5-Trisphosphate 3-Kinase B Is a Negative Regulator of BCR Signaling That Controls B Cell Selection and Tolerance Induction

(2009) A. T. Miller et al.   JOURNAL OF IMMUNOLOGY

CD14 regulates the dendritic cell life cycle after LPS exposure through NFAT activation

(2009) Ivan Zanoni et al.   NATURE

Characterization of YM-58483/BTP2, a novel store-operated Ca2+ entry blocker, on T cell-mediated immune responses in vivo

(2008) Keiko Ohga et al.   INTERNATIONAL IMMUNOPHARMACOLOGY

Dual functions for the endoplasmic reticulum calcium sensors STIM1 and STIM2 in T cell activation and tolerance

(2008) Masatsugu Oh-hora et al.   NATURE IMMUNOLOGY

Inositol trisphosphate 3-kinase B (InsP3KB) as a physiological modulator of myelopoiesis

(2008) Y. Jia et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Design of an Amphiphilic Polymer for Nanoparticle Coating and Functionalization

(2008) Cheng-An J. Lin et al.   Small