Calcineurin/NFAT signaling and innate host defence: a role for NOD1-mediated phagocytic functions

Calcineurin Inhibitor Nephrotoxicity: A Review and Perspective of the Evidence

(2013) Naim Issa et al.   AMERICAN JOURNAL OF NEPHROLOGY

RhoGTPases — NODes for effector-triggered immunity in animals

(2013) Lynda M Stuart et al.   CELL RESEARCH

Manipulation of small Rho GTPases is a pathogen-induced process detected by NOD1

(2013) A. Marijke Keestra et al.   NATURE

Cyclosporine A Impairs Nucleotide Binding Oligomerization Domain (Nod1)-Mediated Innate Antibacterial Renal Defenses in Mice and Human Transplant Recipients

(2013) Emilie Tourneur et al.   PLoS Pathogens

NFAT control of innate immunity

(2012) J. Fric et al.   BLOOD

Common Infections in Kidney Transplant Recipients

(2012) S. Karuthu et al.   Clinical Journal of the American Society of Nephrology

A new eye on NLR proteins: focused on clarity or diffused by complexity?

(2012) Vera Bonardi et al.   CURRENT OPINION IN IMMUNOLOGY

Calcineurin/NFAT signalling inhibits myeloid haematopoiesis

(2012) Jan Fric et al.   EMBO Molecular Medicine

Regulation and dysregulation of innate immunity by NFAT signaling downstream of pattern recognition receptors (PRRs)

(2012) Ivan Zanoni et al.   EUROPEAN JOURNAL OF IMMUNOLOGY

Modulating immunity as a therapy for bacterial infections

(2012) Robert E. W. Hancock et al.   NATURE REVIEWS MICROBIOLOGY

A Cell Permeable Peptide Inhibitor of NFAT Inhibits Macrophage Cytokine Expression and Ameliorates Experimental Colitis

(2012) Houda Z. Elloumi et al.   PLoS One

Nuclear presence of nuclear factor of activated T cells (NFAT) c3 and c4 is required for Toll-like receptor-activated innate inflammatory response of monocytes/macrophages

(2011) Hiroshi Minematsu et al.   CELLULAR SIGNALLING

Pathogen-Derived Effectors Trigger Protective Immunity via Activation of the Rac2 Enzyme and the IMD or Rip Kinase Signaling Pathway

(2011) Laurent Boyer et al.   IMMUNITY

Nucleotide-Binding Oligomerization Domain 1 Mediates Recognition of Clostridium difficile and Induces Neutrophil Recruitment and Protection against the Pathogen

(2011) M. Hasegawa et al.   JOURNAL OF IMMUNOLOGY

The kinase LRRK2 is a regulator of the transcription factor NFAT that modulates the severity of inflammatory bowel disease

(2011) Zhihua Liu et al.   NATURE IMMUNOLOGY

The Inflammasomes

(2010) Kate Schroder et al.   CELL

Pattern Recognition Receptors and Inflammation

(2010) Osamu Takeuchi et al.   CELL

Nod-like receptors: sentinels at host membranes

(2010) Dana J Philpott et al.   CURRENT OPINION IN IMMUNOLOGY

Calcineurin regulates innate antifungal immunity in neutrophils

(2010) Matthew B. Greenblatt et al.   JOURNAL OF EXPERIMENTAL MEDICINE

Genome-wide meta-analysis increases to 71 the number of confirmed Crohn's disease susceptibility loci

(2010) Andre Franke et al.   NATURE GENETICS

Recognition of peptidoglycan from the microbiota by Nod1 enhances systemic innate immunity

(2010) Thomas B Clarke et al.   NATURE MEDICINE

Novel inhibitors of the calcineurin/NFATc hub - alternatives to CsA and FK506?

(2009) Matthias Sieber et al.   Cell Communication and Signaling

Chronic Calcineurin Inhibitor Nephrotoxicity: Reflections on an Evolving Paradigm

(2009) R. S. Gaston   Clinical Journal of the American Society of Nephrology

Neutrophil Migration During Liver Injury Is Under Nucleotide-Binding Oligomerization Domain 1 Control

(2009) Sébastien Dharancy et al.   GASTROENTEROLOGY

Calcineurin inactivation leads to decreased responsiveness to LPS in macrophages and dendritic cells and protects against LPS-induced toxicity in vivo

(2009) Charay Jennings et al.   Innate Immunity

The roles of TLRs, RLRs and NLRs in pathogen recognition

(2009) T. Kawai et al.   INTERNATIONAL IMMUNOLOGY

pH-dependent Internalization of Muramyl Peptides from Early Endosomes Enables Nod1 and Nod2 Signaling

(2009) Jooeun Lee et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Rac1 regulates peptidoglycan-induced nuclear factor-κB activation and cyclooxygenase-2 expression in RAW 264.7 macrophages by activating the phosphatidylinositol 3-kinase/Akt pathway

(2009) Bing-Chang Chen et al.   MOLECULAR IMMUNOLOGY

CD14 regulates the dendritic cell life cycle after LPS exposure through NFAT activation

(2009) Ivan Zanoni et al.   NATURE

Salmonella Typhimurium Type III Secretion Effectors Stimulate Innate Immune Responses in Cultured Epithelial Cells

(2009) Vincent M. Bruno et al.   PLoS Pathogens

Cells on the run: shear-regulated integrin activation in leukocyte rolling and arrest on endothelial cells

(2008) Ronen Alon et al.   CURRENT OPINION IN CELL BIOLOGY

Genome-wide association defines more than 30 distinct susceptibility loci for Crohn's disease

(2008) Jeffrey C Barrett et al.   NATURE GENETICS

GEF-H1 Mediated Control of NOD1 Dependent NF-κB Activation by Shigella Effectors

(2008) Atsuko Fukazawa et al.   PLoS Pathogens