Organocatalytic Asymmetric Michael/Cyclization Cascade Reaction of 3-Isothiocyanato Oxindoles with Maleimides for the Efficient Construction of Pyrrolidonyl Spirooxindoles

Organocatalytic cascade Michael/Michael reaction for the asymmetric synthesis of spirooxindoles containing five contiguous stereocenters

(2016) Bo-Liang Zhao et al.   CHEMICAL COMMUNICATIONS

Recent Advances of α-Isothiocyanato Compounds in the Catalytic Asymmetric Reaction

(2015) Wen-Yong Han et al.   ADVANCED SYNTHESIS & CATALYSIS

Diastereo- and Enantioselective Synthesis of Chiral Pyrrolidine-Fused SpirooxindolesviaOrganocatalytic [3+2] 1,3-Dipolar Cycloaddition of Azomethine Ylides with Maleimides

(2015) Hong-Wu Zhao et al.   ADVANCED SYNTHESIS & CATALYSIS

Highly Stereoselective [4+2] and [3+2] Spiroannulations of 2-(2-Oxoindolin-3-ylidene)acetic Esters Catalyzed by Bifunctional Thioureas

(2015) Magda Monari et al.   CHEMISTRY-A EUROPEAN JOURNAL

Diastereoselective Synthesis of Dispirobarbiturates through Et3N-Catalyzed [3 + 2] Cycloaddition of Barbiturate-Based Olefins with 3-Isothiocyanato Oxindoles

(2015) Hong-Wu Zhao et al.   JOURNAL OF ORGANIC CHEMISTRY

Catalytic Asymmetric [3 + 2] Cyclization Reactions of 3-Isothiocyanato Oxindoles and Alkynyl Ketones Via an in Situ Generated Magnesium Catalyst

(2015) Linqing Wang et al.   ORGANIC LETTERS

Asymmetric Organocatalytic Direct C(sp2)H/C(sp3)H Oxidative Cross-Coupling by Chiral Iodine Reagents

(2014) Hua Wu et al.   ANGEWANDTE CHEMIE-INTERNATIONAL EDITION

A Mannich/cyclization cascade process for the asymmetric synthesis of spirocyclic thioimidazolidineoxindoles

(2014) Hao Cai et al.   CHEMICAL COMMUNICATIONS

Enantioselective Cascade Michael Addition/Cyclization Reactions of 3-Nitro-2H-Chromenes with 3-Isothiocyanato Oxindoles: Efficient Synthesis of Functionalized Polycyclic Spirooxindoles

(2014) Fen Tan et al.   CHEMISTRY-A EUROPEAN JOURNAL

Organocatalytic Asymmetric Assembly Reactions: Synthesis of Spirooxindoles via Organocascade Strategies

(2014) Daojuan Cheng et al.   ACS Catalysis

Enantioselective Construction of Spirooxindole Derivatives: Asymmetric [3+2] Cyclization of Isothiocyanatooxindoles with Allenic Esters or 2-Butynedioic Acid Diesters

(2013) Dan Du et al.   ADVANCED SYNTHESIS & CATALYSIS

Highly Enantioselective Organocatalytic Michael Addition/Cyclization Cascade Reaction of Ylideneoxindoles with Isothiocyanato Oxindoles: A Formal [3+2] Cycloaddition Approach to Optically Active Bispirooxindole Derivatives

(2013) Fen Tan et al.   EUROPEAN JOURNAL OF ORGANIC CHEMISTRY

Highly Efficient and Stereocontrolled Construction of 3,3′-Pyrrolidonyl Spirooxindoles via Organocatalytic Domino Michael/Cyclization Reaction

(2013) Xiong-Li Liu et al.   ORGANIC LETTERS

Highly efficient synthesis of spiro[oxazolidine-2-thione-oxindoles] with 3-isothiocyanato oxindoles and aldehydes via an organocatalytic cascade aldol-cyclization reaction

(2013) Wen-Bing Chen et al.   TETRAHEDRON

Catalytic Asymmetric Synthesis of Spirooxindoles by a Mannich-Type Reaction of Isothiocyanato Oxindoles

(2012) Shota Kato et al.   ANGEWANDTE CHEMIE-INTERNATIONAL EDITION

An organocatalytic Michael-aldol cascade: formal [3+2] annulation to construct enantioenriched spirocyclic oxindole derivatives

(2012) Shu-Wen Duan et al.   CHEMICAL COMMUNICATIONS

Highly Efficient Enantioselective Construction of Bispirooxindoles Containing Three Stereocenters through an Organocatalytic Cascade Michael-Cyclization Reaction

(2012) Hao Wu et al.   CHEMISTRY-A EUROPEAN JOURNAL

Catalytic Asymmetric Michael Addition/Cyclization of Isothiocyanato Oxindoles: Highly Efficient and Versatile Approach for the Synthesis of 3,2′-Pyrrolidinyl Mono- and Bi-spirooxindole Frameworks

(2012) Yi-Ming Cao et al.   CHEMISTRY-A EUROPEAN JOURNAL

Organocatalytic Direct Asymmetric Aldol Reactions of 3-Isothiocyanato Oxindoles to Ketones: Stereocontrolled Synthesis of Spirooxindoles Bearing Highly Congested Contiguous Tetrasubstituted Stereocenters

(2011) Wen-Bing Chen et al.   ORGANIC LETTERS

Asymmetic Organocatalytic 1,3-Dipolar Cycloaddition of Azomethine Ylide to Methyl 2-(2-Nitrophenyl)acrylate for the Synthesis of Diastereoisomers of Spirotryprostatin A

(2011) Mou-Nuo Cheng et al.   ORGANIC LETTERS

Organocatalytic Synthesis of Spiro[pyrrolidin-3,3′-oxindoles] with High Enantiopurity and Structural Diversity

(2009) Xiao-Hua Chen et al.   JOURNAL OF THE AMERICAN CHEMICAL SOCIETY

Stereoselective Synthesis of Spirooxindoles by Palladium-Catalyzed Decarboxylative Cyclization of γ-Methylidene-δ-valerolactones with Isatins

(2009) Ryo Shintani et al.   ORGANIC LETTERS

Regioselective synthesis of dispiro[1H-indene-2,3′-pyrrolidine-2′,3″-[3H]indole]-1,2″(1″H)-diones of potential anti-tumor properties

(2008) Adel S. Girgis   EUROPEAN JOURNAL OF MEDICINAL CHEMISTRY

Discovery of Antimycobacterial Spiro-piperidin-4-ones: An Atom Economic, Stereoselective Synthesis, and Biological Intervention

(2008) Raju Ranjith Kumar et al.   JOURNAL OF MEDICINAL CHEMISTRY