Enabling Photoactivated Cross-linking Mass Spectrometric Analysis of Protein Complexes by Novel MS-cleavable Cross-linkers

Structural dynamics of the human COP9 signalosome revealed by cross-linking mass spectrometry and integrative modeling

(2020) Craig Gutierrez et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Exploring Spacer Arm Structures for Designs of Asymmetric Sulfoxide-Containing MS-Cleavable Cross-Linkers

(2020) Clinton Yu et al.   ANALYTICAL CHEMISTRY

Probing H2O2-mediated Structural Dynamics of the Human 26S Proteasome Using Quantitative Cross-linking Mass Spectrometry (QXL-MS)

(2019) Clinton Yu et al.   MOLECULAR & CELLULAR PROTEOMICS

Altered Domain Structure of the Prion Protein Caused by Cu2+ Binding and Functionally Relevant Mutations: Analysis by Cross-Linking, MS/MS, and NMR

(2019) Alex J. McDonald et al.   STRUCTURE

Photocaged Quinone Methide Crosslinkers for Light-Controlled Chemical Crosslinking of Protein-Protein and Protein-DNA Complexes

(2019) Jun Liu et al.   ANGEWANDTE CHEMIE-INTERNATIONAL EDITION

Improving mass spectrometry analysis of protein structures with arginine-selective chemical cross-linkers

(2019) Alexander X. Jones et al.   Nature Communications

High-density chemical cross-linking for modeling protein interactions

(2019) Julian Mintseris et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Carboxyl-Photo-Reactive MS-Cleavable Cross-Linkers: Unveiling a Hidden Aspect of Diazirine-Based Reagents

(2018) Claudio Iacobucci et al.   ANALYTICAL CHEMISTRY

Carboxylate-Selective Chemical Cross-Linkers for Mass Spectrometric Analysis of Protein Structures

(2018) Xiaoyun Zhang et al.   ANALYTICAL CHEMISTRY

XPlex: An Effective, Multiplex Cross-Linking Chemistry for Acidic Residues

(2018) Mariana Fioramonte et al.   ANALYTICAL CHEMISTRY

Development of a Novel Sulfoxide-Containing MS-Cleavable Homobifunctional Cysteine-Reactive Cross-Linker for Studying Protein–Protein Interactions

(2018) Craig B. Gutierrez et al.   ANALYTICAL CHEMISTRY

Cross-Linking/Mass Spectrometry for Studying Protein Structures and Protein-Protein Interactions: Where Are We Now and Where Should We Go from Here?

(2018) Andrea Sinz   ANGEWANDTE CHEMIE-INTERNATIONAL EDITION

Structure and Function of the 26S Proteasome

(2018) Jared A.M. Bard et al.   Annual Review of Biochemistry

The First MS-Cleavable, Photo-Thiol-Reactive Cross-Linker for Protein Structural Studies

(2018) Claudio Iacobucci et al.   JOURNAL OF THE AMERICAN SOCIETY FOR MASS SPECTROMETRY

Protein Tertiary Structure by Crosslinking/Mass Spectrometry

(2018) Michael Schneider et al.   TRENDS IN BIOCHEMICAL SCIENCES

Integrative structure and functional anatomy of a nuclear pore complex

(2018) Seung Joong Kim et al.   NATURE

Photo-Cross-Linking Mass Spectrometry and Integrative Modeling Enables Rapid Screening of Antigen Interactions Involving Bacterial Transferrin Receptors

(2018) Daniel S. Ziemianowicz et al.   JOURNAL OF PROTEOME RESEARCH

Cross-linking mass spectrometry: methods and applications in structural, molecular and systems biology

(2018) Francis J. O’Reilly et al.   NATURE STRUCTURAL & MOLECULAR BIOLOGY

Proximity-enhanced SuFEx chemical cross-linker for specific and multitargeting cross-linking mass spectrometry

(2018) Bing Yang et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Chemical cross-linking with mass spectrometry: a tool for systems structural biology

(2018) Juan D Chavez et al.   CURRENT OPINION IN CHEMICAL BIOLOGY

The proteasome-interacting Ecm29 protein disassembles the 26S proteasome in response to oxidative stress

(2017) Xiaorong Wang et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Amino Acid Insertion Frequencies Arising from Photoproducts Generated Using Aliphatic Diazirines

(2017) Daniel S. Ziemianowicz et al.   JOURNAL OF THE AMERICAN SOCIETY FOR MASS SPECTROMETRY

Molecular Details Underlying Dynamic Structures and Regulation of the Human 26S Proteasome

(2017) Xiaorong Wang et al.   MOLECULAR & CELLULAR PROTEOMICS

Solving protein structures using short-distance cross-linking constraints as a guide for discrete molecular dynamics simulations

(2017) Nicholas I. Brodie et al.   Science Advances

Divide and conquer: cleavable cross-linkers to study protein conformation and protein–protein interactions

(2016) Andrea Sinz   ANALYTICAL AND BIOANALYTICAL CHEMISTRY

Developing a Multiplexed Quantitative Cross-Linking Mass Spectrometry Platform for Comparative Structural Analysis of Protein Complexes

(2016) Clinton Yu et al.   ANALYTICAL CHEMISTRY

Developing an Acidic Residue Reactive and Sulfoxide-Containing MS-Cleavable Homobifunctional Cross-Linker for Probing Protein–Protein Interactions

(2016) Craig B. Gutierrez et al.   ANALYTICAL CHEMISTRY

Increasing the Depth of Mass-Spectrometry-Based Structural Analysis of Protein Complexes through the Use of Multiple Cross-Linkers

(2016) Yue-He Ding et al.   ANALYTICAL CHEMISTRY

Recent advances in the structural biology of the 26S proteasome

(2016) Marc Wehmer et al.   INTERNATIONAL JOURNAL OF BIOCHEMISTRY & CELL BIOLOGY

The novel isotopically coded short-range photo-reactive crosslinker 2,4,6-triazido-1,3,5-triazine (TATA) for studying protein structures

(2016) Nicholas I. Brodie et al.   Journal of Proteomics

Crosslinking and Mass Spectrometry: An Integrated Technology to Understand the Structure and Function of Molecular Machines

(2016) Alexander Leitner et al.   TRENDS IN BIOCHEMICAL SCIENCES

Isotopically-coded short-range hetero-bifunctional photo-reactive crosslinkers for studying protein structure

(2015) Nicholas I. Brodie et al.   Journal of Proteomics

Extending the cross-linking/mass spectrometry strategy: Facile incorporation of photo-activatable amino acids into the model protein calmodulin in Escherichia coli cells

(2015) Christine Piotrowski et al.   METHODS

Serum Albumin Domain Structures in Human Blood Serum by Mass Spectrometry and Computational Biology

(2015) Adam Belsom et al.   MOLECULAR & CELLULAR PROTEOMICS

Proteome-wide profiling of protein assemblies by cross-linking mass spectrometry

(2015) Fan Liu et al.   NATURE METHODS

Synthesis of two new enrichable and MS-cleavable cross-linkers to define protein–protein interactions by mass spectrometry

(2015) Anthony M. Burke et al.   ORGANIC & BIOMOLECULAR CHEMISTRY

Structural characterization of the interaction of Ubp6 with the 26S proteasome

(2015) Antje Aufderheide et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Gln40 deamidation blocks structural reconfiguration and activation of SCF ubiquitin ligase complex by Nedd8

(2015) Clinton Yu et al.   Nature Communications

Developing New Isotope-Coded Mass Spectrometry-Cleavable Cross-Linkers for Elucidating Protein Structures

(2014) Clinton Yu et al.   ANALYTICAL CHEMISTRY

A Newin VivoCross-linking Mass Spectrometry Platform to Define Protein–Protein Interactions in Living Cells

(2014) Robyn M. Kaake et al.   MOLECULAR & CELLULAR PROTEOMICS

Structural Characterization by Cross-linking Reveals the Detailed Architecture of a Coatomer-related Heptameric Module from the Nuclear Pore Complex

(2014) Yi Shi et al.   MOLECULAR & CELLULAR PROTEOMICS

Deep classification of a large cryo-EM dataset defines the conformational landscape of the 26S proteasome

(2014) P. Unverdorben et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Chemical cross-linking/mass spectrometry targeting acidic residues in proteins and protein complexes

(2014) Alexander Leitner et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Mapping the Structural Topology of the Yeast 19S Proteasomal Regulatory Particle Using Chemical Cross-linking and Probabilistic Modeling

(2012) Athit Kao et al.   MOLECULAR & CELLULAR PROTEOMICS

Expanding the Chemical Cross-Linking Toolbox by the Use of Multiple Proteases and Enrichment by Size Exclusion Chromatography

(2012) Alexander Leitner et al.   MOLECULAR & CELLULAR PROTEOMICS

Structural Probing of a Protein Phosphatase 2A Network by Chemical Cross-Linking and Mass Spectrometry

(2012) F. Herzog et al.   SCIENCE

Xwalk: computing and visualizing distances in cross-linking experiments

(2011) Abdullah Kahraman et al.   BIOINFORMATICS

Development of a Novel Cross-linking Strategy for Fast and Accurate Identification of Cross-linked Peptides of Protein Complexes

(2010) Athit Kao et al.   MOLECULAR & CELLULAR PROTEOMICS

Probing Native Protein Structures by Chemical Cross-linking, Mass Spectrometry, and Bioinformatics

(2010) Alexander Leitner et al.   MOLECULAR & CELLULAR PROTEOMICS

Regulation of the 26S Proteasome Complex During Oxidative Stress

(2010) X. Wang et al.   Science Signaling

Recognition and Processing of Ubiquitin-Protein Conjugates by the Proteasome

(2009) Daniel Finley   Annual Review of Biochemistry

Universal sample preparation method for proteome analysis

(2009) Jacek R Wiśniewski et al.   NATURE METHODS