The First MS-Cleavable, Photo-Thiol-Reactive Cross-Linker for Protein Structural Studies

Carboxyl-Photo-Reactive MS-Cleavable Cross-Linkers: Unveiling a Hidden Aspect of Diazirine-Based Reagents

(2018) Claudio Iacobucci et al.   ANALYTICAL CHEMISTRY

Genetically encoded photocross-linkers determine the biological binding site of exendin-4 peptide in the N-terminal domain of the intact human glucagon-like peptide-1 receptor (GLP-1R)

(2017) Cassandra Koole et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Genetically Encoded 2-Aryl-5-carboxytetrazoles for Site-Selective Protein Photo-Cross-Linking

(2017) Yulin Tian et al.   JOURNAL OF THE AMERICAN CHEMICAL SOCIETY

Novel Concepts of MS-Cleavable Cross-linkers for Improved Peptide Structure Analysis

(2017) Christoph Hage et al.   JOURNAL OF THE AMERICAN SOCIETY FOR MASS SPECTROMETRY

A Novel MS-Cleavable Azo Cross-Linker for Peptide Structure Analysis by Free Radical Initiated Peptide Sequencing (FRIPS)

(2017) Claudio Iacobucci et al.   JOURNAL OF THE AMERICAN SOCIETY FOR MASS SPECTROMETRY

Molecular Details Underlying Dynamic Structures and Regulation of the Human 26S Proteasome

(2017) Xiaorong Wang et al.   MOLECULAR & CELLULAR PROTEOMICS

6S RNA Mimics B-Form DNA to Regulate Escherichia coli RNA Polymerase

(2017) James Chen et al.   MOLECULAR CELL

Mass spectrometry-based cross-linking study shows that the Psb28 protein binds to cytochromeb559in Photosystem II

(2017) Daniel A. Weisz et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Mitochondrial protein interactome elucidated by chemical cross-linking mass spectrometry

(2017) Devin K. Schweppe et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Spontaneous and specific chemical cross-linking in live cells to capture and identify protein interactions

(2017) Bing Yang et al.   Nature Communications

Architecture of the RNA polymerase II-Paf1C-TFIIS transcription elongation complex

(2017) Youwei Xu et al.   Nature Communications

A short linear motif in scaffold Nup145C connects Y-complex with pre-assembled outer ring Nup82 complex

(2017) Roman Teimer et al.   Nature Communications

Optimized fragmentation schemes and data analysis strategies for proteome-wide cross-link identification

(2017) Fan Liu et al.   Nature Communications

Solving protein structures using short-distance cross-linking constraints as a guide for discrete molecular dynamics simulations

(2017) Nicholas I. Brodie et al.   Science Advances

Integrated Workflow for Structural Proteomics Studies Based on Cross-Linking/Mass Spectrometry with an MS/MS Cleavable Cross-Linker

(2016) Christian Arlt et al.   ANALYTICAL CHEMISTRY

Impact of the Molecular Environment on Thiol–Ene Coupling For Biofunctionalization and Conjugation

(2016) Burcu Colak et al.   BIOCONJUGATE CHEMISTRY

Structure and Function of the Nuclear Pore Complex Cytoplasmic mRNA Export Platform

(2016) Javier Fernandez-Martinez et al.   CELL

Monitoring Solution Structures of Peroxisome Proliferator-Activated Receptor β/δ upon Ligand Binding

(2016) Rico Schwarz et al.   PLoS One

Blind testing of cross-linking/mass spectrometry hybrid methods in CASP11

(2016) Michael Schneider et al.   PROTEINS-STRUCTURE FUNCTION AND BIOINFORMATICS

Crosslinking and Mass Spectrometry: An Integrated Technology to Understand the Structure and Function of Molecular Machines

(2016) Alexander Leitner et al.   TRENDS IN BIOCHEMICAL SCIENCES

Repression of RNA polymerase by the archaeo-viral regulator ORF145/RIP

(2016) Carol Sheppard et al.   Nature Communications

Isotopically-coded short-range hetero-bifunctional photo-reactive crosslinkers for studying protein structure

(2015) Nicholas I. Brodie et al.   Journal of Proteomics

Extending the cross-linking/mass spectrometry strategy: Facile incorporation of photo-activatable amino acids into the model protein calmodulin in Escherichia coli cells

(2015) Christine Piotrowski et al.   METHODS

Photo-lysine captures proteins that bind lysine post-translational modifications

(2015) Tangpo Yang et al.   Nature Chemical Biology

Proteome-wide profiling of protein assemblies by cross-linking mass spectrometry

(2015) Fan Liu et al.   NATURE METHODS

Quantitative Analysis of T Cell Receptor Complex Interaction Sites Using Genetically Encoded Photo-Cross-Linkers

(2014) Wenjuan Wang et al.   ACS Chemical Biology

Click Chemistry in Complex Mixtures: Bioorthogonal Bioconjugation

(2014) Craig S. McKay et al.   CHEMISTRY & BIOLOGY

The advancement of chemical cross-linking and mass spectrometry for structural proteomics: from single proteins to protein interaction networks

(2014) Andrea Sinz   Expert Review of Proteomics

Automated Assignment of MS/MS Cleavable Cross-Links in Protein 3D-Structure Analysis

(2014) Michael Götze et al.   JOURNAL OF THE AMERICAN SOCIETY FOR MASS SPECTROMETRY

A Newin VivoCross-linking Mass Spectrometry Platform to Define Protein–Protein Interactions in Living Cells

(2014) Robyn M. Kaake et al.   MOLECULAR & CELLULAR PROTEOMICS

Synthesis of Non-linear Protein Dimers through a Genetically Encoded Thiol-ene Reaction

(2014) Jessica Torres-Kolbus et al.   PLoS One

Chemical cross-linking/mass spectrometry targeting acidic residues in proteins and protein complexes

(2014) Alexander Leitner et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Matching Cross-linked Peptide Spectra: Only as Good as the Worse Identification

(2013) Michael J. Trnka et al.   MOLECULAR & CELLULAR PROTEOMICS

Photoactivable Amino Acid Bioisosteres and Mass Spectrometry: Snapshots of in Vivo 3D Protein Structures

(2012) Claudio Iacobucci et al.   CHEMBIOCHEM

Bioconjugation Using Thiols: Old Chemistry Rediscovered to Connect Polymers with Nature’s Building Blocks

(2012) Martina H. Stenzel   ACS Macro Letters

Recent applications of thiol–ene coupling as a click process for glycoconjugation

(2011) Alessandro Dondoni et al.   CHEMICAL SOCIETY REVIEWS

In Vivo Application of Photocleavable Protein Interaction Reporter Technology

(2011) Li Yang et al.   JOURNAL OF PROTEOME RESEARCH

CrossWork: Software-assisted identification of cross-linked peptides

(2011) Morten I. Rasmussen et al.   Journal of Proteomics

Cross-linking Measurements ofIn VivoProtein Complex Topologies

(2011) Chunxiang Zheng et al.   MOLECULAR & CELLULAR PROTEOMICS

The myristoylation of guanylate cyclase-activating protein-2 causes an increase in thermodynamic stability in the presence but not in the absence of Ca2+

(2011) Thomas Schröder et al.   PROTEIN SCIENCE

Cleavable Cross-Linker for Protein Structure Analysis: Reliable Identification of Cross-Linking Products by Tandem MS

(2010) Mathias Q. Müller et al.   ANALYTICAL CHEMISTRY

Use of a Combination of Isotopically Coded Cross-Linkers and Isotopically Coded N-Terminal Modification Reagents for Selective Identification of Inter-peptide Crosslinks

(2010) Evgeniy V. Petrotchenko et al.   ANALYTICAL CHEMISTRY

Thiol-Ene Click Chemistry

(2010) Charles E. Hoyle et al.   ANGEWANDTE CHEMIE-INTERNATIONAL EDITION

The beginning of a beautiful friendship: Cross-linking/mass spectrometry and modelling of proteins and multi-protein complexes

(2010) Juri Rappsilber   JOURNAL OF STRUCTURAL BIOLOGY

Development of a Novel Cross-linking Strategy for Fast and Accurate Identification of Cross-linked Peptides of Protein Complexes

(2010) Athit Kao et al.   MOLECULAR & CELLULAR PROTEOMICS

A new cross-linking strategy: protein interaction reporter (PIR) technology for protein–protein interaction studies

(2010) Xiaoting Tang et al.   Molecular BioSystems

Intra-Molecular Cross-Linking of Acidic Residues for Protein Structure Studies

(2009) Petr Novák et al.   EUROPEAN JOURNAL OF MASS SPECTROMETRY

Circos: An information aesthetic for comparative genomics

(2009) M. Krzywinski et al.   GENOME RESEARCH