Anti-Alzheimer’s Molecules Derived from Marine Life: Understanding Molecular Mechanisms and Therapeutic Potential
出版年份 2021 全文链接
标题
Anti-Alzheimer’s Molecules Derived from Marine Life: Understanding Molecular Mechanisms and Therapeutic Potential
作者
关键词
-
出版物
Marine Drugs
Volume 19, Issue 5, Pages 251
出版商
MDPI AG
发表日期
2021-04-28
DOI
10.3390/md19050251
参考文献
相关参考文献
注意:仅列出部分参考文献,下载原文获取全部文献信息。- Molecular Mechanisms of Astaxanthin as a Potential Neurotherapeutic Agent
- (2021) Eshak I. Bahbah et al. Marine Drugs
- Deciphering the Interacting Mechanisms of Circadian Disruption and Alzheimer’s Disease
- (2021) Md. Sahab Uddin et al. NEUROCHEMICAL RESEARCH
- Emerging Promise of Immunotherapy for Alzheimer’s Disease: A New Hope for the Development of Alzheimer’s Vaccine
- (2020) Md. Tanvir Kabir et al. CURRENT TOPICS IN MEDICINAL CHEMISTRY
- Combination Drug Therapy for the Management of Alzheimer’s Disease
- (2020) Md. Tanvir Kabir et al. INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES
- Molecular Insight into the Therapeutic Promise of Targeting APOE4 for Alzheimer’s Disease
- (2020) Abdullah Al Mamun et al. Oxidative Medicine and Cellular Longevity
- Revisiting the Amyloid Cascade Hypothesis: From Anti-Aβ Therapeutics to Auspicious New Ways for Alzheimer’s Disease
- (2020) Md. Sahab Uddin et al. INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES
- Multi-Target Drug Candidates for Multifactorial Alzheimer’s Disease: AChE and NMDAR as Molecular Targets
- (2020) Md. Sahab Uddin et al. MOLECULAR NEUROBIOLOGY
- Treatment Combinations for Alzheimer’s Disease: Current And Future Pharmacotherapy Options
- (2019) Jeffrey L. Cummings et al. JOURNAL OF ALZHEIMERS DISEASE
- Simplified immunosuppressive and neuroprotective agents based on gracilin A
- (2019) Mikail E. Abbasov et al. Nature Chemistry
- Natural Compounds for Alzheimer’s Disease Therapy: A Systematic Review of Preclinical and Clinical Studies
- (2019) Stephanie Andrade et al. INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES
- Gracilin A Derivatives Target Early Events in Alzheimer’s Disease: in Vitro Effects on Neuroinflammation and Oxidative Stress
- (2019) Rebeca Alvariño et al. ACS Chemical Neuroscience
- Multidomain intervention and/or omega-3 in nondemented elderly subjects according to amyloid status
- (2019) Julien Delrieu et al. Alzheimers & Dementia
- Gracilin-Derivatives as Lead Compounds for Anti-inflammatory Effects
- (2019) Sandra Gegunde et al. CELLULAR AND MOLECULAR NEUROBIOLOGY
- Cholinesterase Inhibitors for Alzheimer's Disease: Multitargeting Strategy Based on Anti-Alzheimer's Drugs Repositioning
- (2019) Md. Tanvir Kabir et al. CURRENT PHARMACEUTICAL DESIGN
- NMDA Receptor Antagonists: Repositioning of Memantine as a Multitargeting Agent for Alzheimer's Therapy
- (2019) Md. Tanvir Kabir et al. CURRENT PHARMACEUTICAL DESIGN
- Review of bioactive secondary metabolites from marine bryozoans in the progress of new drugs discovery
- (2018) Xiang Rong Tian et al. Future Medicinal Chemistry
- GTS-21 attenuates loss of body mass, muscle mass, and function in rats having systemic inflammation with and without disuse atrophy
- (2018) Stefan J. Schaller et al. PFLUGERS ARCHIV-EUROPEAN JOURNAL OF PHYSIOLOGY
- Bryostatin-1 alleviates experimental multiple sclerosis
- (2018) Michael D. Kornberg et al. PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA
- Reconsideration of Amyloid Hypothesis and Tau Hypothesis in Alzheimer's Disease
- (2018) Fuyuki Kametani et al. Frontiers in Neuroscience
- Effects of docosahexaenoic acid–rich n−3 fatty acid supplementation on cytokine release from blood mononuclear leukocytes: the OmegAD study
- (2018) Inger Vedin et al. AMERICAN JOURNAL OF CLINICAL NUTRITION
- Enhanced Brain Amyloid-β Clearance by Rifampicin and Caffeine as a Possible Protective Mechanism Against Alzheimer's Disease
- (2018) Hisham Qosa et al. JOURNAL OF ALZHEIMERS DISEASE
- A Randomized, Double-Blind, Placebo-Controlled, Phase II Study Assessing Safety, Tolerability, and Efficacy of Bryostatin in the Treatment of Moderately Severe to Severe Alzheimer’s Disease
- (2018) Martin R. Farlow et al. JOURNAL OF ALZHEIMERS DISEASE
- Bryostatin Effects on Cognitive Function and PKCɛ in Alzheimer’s Disease Phase IIa and Expanded Access Trials
- (2017) Thomas J. Nelson et al. JOURNAL OF ALZHEIMERS DISEASE
- Effect of long-term omega 3 polyunsaturated fatty acid supplementation with or without multidomain intervention on cognitive function in elderly adults with memory complaints (MAPT): a randomised, placebo-controlled trial
- (2017) Sandrine Andrieu et al. LANCET NEUROLOGY
- Emerging and Neglected Infectious Diseases: Insights, Advances, and Challenges
- (2017) Nicholas Israel Nii-Trebi Biomed Research International
- Reversal of cognitive decline in Alzheimer's disease
- (2016) Dale Bredesen et al. Aging-US
- Marine-Derived Pharmaceuticals - Challenges and Opportunities
- (2016) Ulrike Lindequist Biomolecules & Therapeutics
- Rifampicin is a candidate preventive medicine against amyloid-β and tau oligomers
- (2016) Tomohiro Umeda et al. BRAIN
- Apolipoprotein E as a Therapeutic Target in Alzheimer’s Disease: A Review of Basic Research and Clinical Evidence
- (2016) Yu Yamazaki et al. CNS DRUGS
- The amyloid hypothesis of Alzheimer's disease at 25 years
- (2016) Dennis J Selkoe et al. EMBO Molecular Medicine
- Killing Me Softly: Connotations to Unfolded Protein Response and Oxidative Stress in Alzheimer’s Disease
- (2016) Beata Pająk et al. Oxidative Medicine and Cellular Longevity
- A fixed-dose combination of memantine extended-release and donepezil in the treatment of moderate-to-severe Alzheimer’s disease
- (2016) William James Deardorff et al. Drug Design Development and Therapy
- Evaluation of the brain-penetrant microtubule-stabilizing agent, dictyostatin, in the PS19 tau transgenic mouse model of tauopathy
- (2016) Vishruti Makani et al. Acta Neuropathologica Communications
- Acute Oral Bryostatin-1 Administration Improves Learning Deficits in the APP/PS1 Transgenic Mouse Model of Alzheimer’s Disease
- (2015) L.M. Schrott et al. Current Alzheimer Research
- New Drugs from Marine Organisms in Alzheimer’s Disease
- (2015) Patrizia Russo et al. Marine Drugs
- Memory recuperative potential of rifampicin in aluminum chloride-induced dementia: Role of pregnane X receptors
- (2015) P. Kaur et al. NEUROSCIENCE
- The Streptomyces metabolite anhydroexfoliamycin ameliorates hallmarks of Alzheimer’s disease in vitro and in vivo
- (2015) M. Leirós et al. NEUROSCIENCE
- Towards universal therapeutics for memory disorders
- (2015) Miao-Kun Sun et al. TRENDS IN PHARMACOLOGICAL SCIENCES
- Beyond Acetylcholinesterase Inhibitors for Treating Alzheimer&aposs Disease: .α7-nAChR Agonists in Human Clinical Trials
- (2014) Patrizia Russo et al. CURRENT PHARMACEUTICAL DESIGN
- Targeting the β secretase BACE1 for Alzheimer's disease therapy
- (2014) Riqiang Yan et al. LANCET NEUROLOGY
- Spongionella Secondary Metabolites Protect Mitochondrial Function in Cortical Neurons against Oxidative Stress
- (2014) Marta Leirós et al. Marine Drugs
- Marketed Marine Natural Products in the Pharmaceutical and Cosmeceutical Industries: Tips for Success
- (2014) Ana Martins et al. Marine Drugs
- Alzheimer’s disease drug-development pipeline: few candidates, frequent failures
- (2014) Jeffrey L Cummings et al. Alzheimers Research & Therapy
- The low-density lipoprotein receptor-related protein 1 and amyloid-β clearance in Alzheimer’s disease
- (2014) Takahisa Kanekiyo et al. Frontiers in Aging Neuroscience
- Physical activity reduces hippocampal atrophy in elders at genetic risk for Alzheimer's disease
- (2014) J. Carson Smith et al. Frontiers in Aging Neuroscience
- Mitigation of ROS Insults by Streptomyces Secondary Metabolites in Primary Cortical Neurons
- (2013) Marta Leirós et al. ACS Chemical Neuroscience
- Benefit of 13-desmethyl Spirolide C Treatment in Triple Transgenic Mouse Model of Alzheimer Disease: Beta-Amyloid and Neuronal Markers Improvement
- (2013) Eva Alonso et al. Current Alzheimer Research
- Acetylcholinesterase Inhibitors: Pharmacology and Toxicology
- (2013) Mirjana B. Colovic et al. Current Neuropharmacology
- Transfer of omega-3 fatty acids across the blood-brain barrier after dietary supplementation with a docosahexaenoic acid-rich omega-3 fatty acid preparation in patients with Alzheimer's disease: the OmegAD study
- (2013) Y. Freund Levi et al. JOURNAL OF INTERNAL MEDICINE
- Apolipoprotein E and Alzheimer disease: risk, mechanisms and therapy
- (2013) Chia-Chen Liu et al. Nature Reviews Neurology
- PKC activation during training restores mushroom spine synapses and memory in the aged rat
- (2013) Jarin Hongpaisan et al. NEUROBIOLOGY OF DISEASE
- Oral Treatment Targeting the Unfolded Protein Response Prevents Neurodegeneration and Clinical Disease in Prion-Infected Mice
- (2013) J. A. Moreno et al. Science Translational Medicine
- Modification of the Relationship of the Apolipoprotein E ε4 Allele to the Risk of Alzheimer Disease and Neurofibrillary Tangle Density by Sleep
- (2013) Andrew S. P. Lim et al. JAMA Neurology
- AlzPathway: a comprehensive map of signaling pathways of Alzheimer’s disease
- (2012) Satoshi Mizuno et al. BMC Systems Biology
- 3-(2,4-Dimethoxybenzylidene)-anabaseine: A promising candidate drug for Alzheimer's disease?
- (2012) Philippe Zawieja et al. Geriatrics & Gerontology International
- A multicenter, blinded, randomized, factorial controlled trial of doxycycline and rifampin for treatment of Alzheimer's disease: the DARAD trial
- (2012) D. William Molloy et al. INTERNATIONAL JOURNAL OF GERIATRIC PSYCHIATRY
- Bryostatin-1 vs. TPPB: Dose-Dependent APP Processing and PKC-α, -δ, and -ε Isoform Activation in SH-SY5Y Neuronal Cells
- (2012) P. Yi et al. JOURNAL OF MOLECULAR NEUROSCIENCE
- Recruitment strategies for preventive trials. The MAPT study (Multidomain Alzheimer Preventive Trial)
- (2012) I. Carrie et al. Journal of Nutrition Health & Aging
- Effects of DHA- Rich n-3 Fatty Acid Supplementation on Gene Expression in Blood Mononuclear Leukocytes: The OmegAD Study
- (2012) Inger Vedin et al. PLoS One
- Tramiprosate in mild-to-moderate Alzheimer’s disease – a randomized, double-blind, placebo-controlled, multi-centre study (the Alphase Study)
- (2011) Paul S. Aisen et al. Archives of Medical Science
- Anatabine lowers Alzheimer's Aβ production in vitro and in vivo
- (2011) Daniel Paris et al. EUROPEAN JOURNAL OF PHARMACOLOGY
- Antibody-based therapy in Alzheimer's disease
- (2011) Refik Pul et al. EXPERT OPINION ON BIOLOGICAL THERAPY
- PKC Activation Prevents Synaptic Loss, A Elevation, and Cognitive Deficits in Alzheimer's Disease Transgenic Mice
- (2011) J. Hongpaisan et al. JOURNAL OF NEUROSCIENCE
- 13-Desmethyl spirolide-C is neuroprotective and reduces intracellular Aβ and hyperphosphorylated tau in vitro
- (2011) Eva Alonso et al. NEUROCHEMISTRY INTERNATIONAL
- Pharmacotherapies for Alzheimer's disease: Beyond cholinesterase inhibitors
- (2011) Haythum O. Tayeb et al. PHARMACOLOGY & THERAPEUTICS
- RETRACTED: SIRT1 Suppresses β-Amyloid Production by Activating the α-Secretase Gene ADAM10
- (2010) Gizem Donmez et al. CELL
- Bryostatins: biological context and biotechnological prospects
- (2010) Amaro E Trindade-Silva et al. CURRENT OPINION IN BIOTECHNOLOGY
- Marine natural products as sources of novel scaffolds: achievement and concern
- (2010) De-Xin Kong et al. DRUG DISCOVERY TODAY
- Docosahexaenoic Acid Supplementation and Cognitive Decline in Alzheimer Disease
- (2010) Joseph F. Quinn et al. JAMA-JOURNAL OF THE AMERICAN MEDICAL ASSOCIATION
- Review Article: Genetics of Alzheimer Disease
- (2010) Lynn M. Bekris et al. JOURNAL OF GERIATRIC PSYCHIATRY AND NEUROLOGY
- Total synthesis of (−)-dictyostatin, a microtubule-stabilising anticancer macrolide of marine sponge origin
- (2010) Ian Paterson et al. TETRAHEDRON
- Late onset Alzheimer’s disease in older people
- (2010) Ahmet Turan Isik Clinical Interventions in Aging
- Commentary on “A roadmap for the prevention of dementia II. Leon Thal Symposium 2008.” The Multidomain Alzheimer Preventive Trial (MAPT): A new approach to the prevention of Alzheimer's disease
- (2009) Sophie Gillette-Guyonnet et al. Alzheimers & Dementia
- Bioactive Diterpene Derivatives from the Marine SpongeSpongionellasp.
- (2009) Mostafa E. Rateb et al. JOURNAL OF NATURAL PRODUCTS
- Lessons learned in the use of volumetric MRI in therapeutic trials in Alzheimer’s disease: The Alzhemedtm (Tramiprosate) experience
- (2009) D. Saumier et al. Journal of Nutrition Health & Aging
- Effect of tramiprosate in patients with mild-to-moderate alzheimer’s disease: Exploratory analyses of the MRI sub-group of the alphase study
- (2009) S. Gauthier et al. Journal of Nutrition Health & Aging
- Cholinergic system during the progression of Alzheimer’s disease: therapeutic implications
- (2008) Elliott J Mufson et al. Expert Review of Neurotherapeutics
- Poststroke neuronal rescue and synaptogenesis mediated in vivo by protein kinase C in adult brains
- (2008) M.-K. Sun et al. PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA
- Inhibition of Amyloid Fibrillization of Hen Egg-White Lysozymes by Rifampicin and p-Benzoquinone
- (2007) Valerie H. Lieu et al. BIOTECHNOLOGY PROGRESS
- Omega-3 supplementation in mild to moderate Alzheimer's disease: effects on neuropsychiatric symptoms
- (2007) Yvonne Freund-Levi et al. INTERNATIONAL JOURNAL OF GERIATRIC PSYCHIATRY
Find Funding. Review Successful Grants.
Explore over 25,000 new funding opportunities and over 6,000,000 successful grants.
ExploreCreate your own webinar
Interested in hosting your own webinar? Check the schedule and propose your idea to the Peeref Content Team.
Create Now