Conformational Dynamics of α-Synuclein during the Interaction with Phospholipid Nanodiscs by Millisecond Hydrogen–Deuterium Exchange Mass Spectrometry
出版年份 2021 全文链接
标题
Conformational Dynamics of α-Synuclein during the Interaction with Phospholipid Nanodiscs by Millisecond Hydrogen–Deuterium Exchange Mass Spectrometry
作者
关键词
-
出版物
JOURNAL OF THE AMERICAN SOCIETY FOR MASS SPECTROMETRY
Volume 32, Issue 5, Pages 1169-1179
出版商
American Chemical Society (ACS)
发表日期
2021-03-31
DOI
10.1021/jasms.0c00463
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注意:仅列出部分参考文献,下载原文获取全部文献信息。- Epitope Mapping for a Preclinical Bevacizumab (Avastin) Biosimilar on an Extended Construct of Vascular Endothelial Growth Factor A Using Millisecond Hydrogen–Deuterium Exchange Mass Spectrometry
- (2020) Kerene A. Brown et al. BIOCHEMISTRY
- Rapid characterization of structural and functional similarity for a candidate bevacizumab (Avastin) biosimilar using a multipronged mass‐spectrometry‐based approach
- (2019) Kerene A. Brown et al. Drug Testing and Analysis
- Mass Spectrometric Analysis of Lewy Body-Enriched α-Synuclein in Parkinson’s Disease
- (2019) Payel Bhattacharjee et al. JOURNAL OF PROTEOME RESEARCH
- Lipids at the Crossroad of α-Synuclein Function and Dysfunction: Biological and Pathological Implications
- (2019) Natalia P. Alza et al. Frontiers in Cellular Neuroscience
- Biasing the native α-synuclein conformational ensemble towards compact states abolishes aggregation and neurotoxicity
- (2019) Anita Carija et al. Redox Biology
- Cellular models of alpha‐synuclein toxicity and aggregation
- (2019) Marion Delenclos et al. JOURNAL OF NEUROCHEMISTRY
- The physiological role of α‐synuclein and its relationship to Parkinson’s Disease
- (2019) David Sulzer et al. JOURNAL OF NEUROCHEMISTRY
- Impact of Cardiolipin and Phosphatidylcholine Interactions on the Conformational Ensemble of Cytochrome c
- (2019) Lisa Szymkowicz et al. BIOCHEMISTRY
- What is strain in neurodegenerative diseases?
- (2019) Ye Tian et al. CELLULAR AND MOLECULAR LIFE SCIENCES
- A Unique Conformational Distortion Mechanism Drives Lipocalin 2 Binding to Bacterial Siderophores
- (2019) Xiaojing Huang et al. ACS Chemical Biology
- Order and disorder in the physiological membrane binding of α-synuclein
- (2018) Giuliana Fusco et al. CURRENT OPINION IN STRUCTURAL BIOLOGY
- Mapping Conformational Dynamics to Individual Steps in the TEM-1 β-Lactamase Catalytic Mechanism
- (2018) Ruth Knox et al. JOURNAL OF MOLECULAR BIOLOGY
- Subcellular localization of alpha-synuclein aggregates and their interaction with membranes
- (2018) Emanuela Colla et al. Neural Regeneration Research
- Dynamics of Scabin toxin. A proposal for the binding mode of the DNA substrate
- (2018) Miguel R. Lugo et al. PLoS One
- Solution NMR of SNAREs, complexin and α-synuclein in association with membrane-mimetics
- (2018) Binyong Liang et al. PROGRESS IN NUCLEAR MAGNETIC RESONANCE SPECTROSCOPY
- Exploring the Structural Diversity in Inhibitors of α-Synuclein Amyloidogenic Folding, Aggregation, and Neurotoxicity
- (2018) Sukanya Das et al. Frontiers in Chemistry
- Interplay between α-synuclein amyloid formation and membrane structure
- (2018) Emma I. O'Leary et al. BIOCHIMICA ET BIOPHYSICA ACTA-PROTEINS AND PROTEOMICS
- Disruptive membrane interactions of alpha-synuclein aggregates
- (2018) Aditya Iyer et al. BIOCHIMICA ET BIOPHYSICA ACTA-PROTEINS AND PROTEOMICS
- An interdomain bridge influences RNA binding of the human La protein
- (2018) Stefano A. Marrella et al. JOURNAL OF BIOLOGICAL CHEMISTRY
- Chemical Additives Enable Native Mass Spectrometry Measurement of Membrane Protein Oligomeric State within Intact Nanodiscs
- (2018) James E. Keener et al. JOURNAL OF THE AMERICAN CHEMICAL SOCIETY
- Recent advances in nanodisc technology for membrane protein studies (2012-2017)
- (2017) John E. Rouck et al. FEBS LETTERS
- The Role of Lipids Interacting with α-Synuclein in the Pathogenesis of Parkinson’s Disease
- (2017) Céline Galvagnion Journal of Parkinsons Disease
- Time-resolved ElectroSpray Ionization Hydrogen-deuterium Exchange Mass Spectrometry for Studying Protein Structure and Dynamics
- (2017) Cristina Lento et al. Jove-Journal of Visualized Experiments
- Hydrogen deuterium exchange mass spectrometry in biopharmaceutical discovery and development – A review
- (2016) Bin Deng et al. ANALYTICA CHIMICA ACTA
- Membrane remodeling and mechanics: Experiments and simulations of α-Synuclein
- (2016) Ana West et al. BIOCHIMICA ET BIOPHYSICA ACTA-BIOMEMBRANES
- Nanodiscs for structural and functional studies of membrane proteins
- (2016) Ilia G Denisov et al. NATURE STRUCTURAL & MOLECULAR BIOLOGY
- Structural basis of synaptic vesicle assembly promoted by α-synuclein
- (2016) Giuliana Fusco et al. Nature Communications
- Nanodiscs for structural and functional studies of membrane proteins
- (2016) Ilia G Denisov et al. NATURE STRUCTURAL & MOLECULAR BIOLOGY
- Alpha-Synuclein in Parkinson’s Disease: From Pathogenetic Dysfunction to Potential Clinical Application
- (2016) Lingjia Xu et al. Parkinsons Disease
- Is Alpha-Synuclein Loss-of-Function a Contributor to Parkinsonian Pathology? Evidence from Non-human Primates
- (2016) Timothy J. Collier et al. Frontiers in Neuroscience
- Bayesian Deconvolution of Mass and Ion Mobility Spectra: From Binary Interactions to Polydisperse Ensembles
- (2015) Michael T. Marty et al. ANALYTICAL CHEMISTRY
- Distinct higher-order α-synuclein oligomers induce intracellular aggregation
- (2015) Eva Illes-Toth et al. BIOCHEMICAL JOURNAL
- Time-resolved electrospray mass spectrometry — a brief history
- (2015) Cristina Lento et al. CANADIAN JOURNAL OF CHEMISTRY
- Ion Mobility—Mass Spectrometry-Based Screening for Inhibition of α-Synuclein Aggregation
- (2015) Yanqin Liu et al. EUROPEAN JOURNAL OF MASS SPECTROMETRY
- Definition of a Molecular Pathway Mediating -Synuclein Neurotoxicity
- (2015) J. Burre et al. JOURNAL OF NEUROSCIENCE
- Lipid vesicles trigger α-synuclein aggregation by stimulating primary nucleation
- (2015) Céline Galvagnion et al. Nature Chemical Biology
- Smaller Nanodiscs are Suitable for Studying Protein Lipid Interactions by Solution NMR
- (2015) Xiaoming Wang et al. PROTEIN JOURNAL
- Hyperphosphorylation of Intrinsically Disordered Tau Protein Induces an Amyloidogenic Shift in Its Conformational Ensemble
- (2015) Shaolong Zhu et al. PLoS One
- Nanodiscs and Electrospray Ionization Mass Spectrometry: A Tool for Screening Glycolipids Against Proteins
- (2014) Aneika C. Leney et al. ANALYTICAL CHEMISTRY
- Probing Conformational Change of Intrinsically Disordered α-Synuclein to Helical Structures by Distinctive Regional Interactions with Lipid Membranes
- (2014) Shin Jung C. Lee et al. ANALYTICAL CHEMISTRY
- Changes in Signal Transducer and Activator of Transcription 3 (STAT3) Dynamics Induced by Complexation with Pharmacological Inhibitors of Src Homology 2 (SH2) Domain Dimerization
- (2014) Diana Resetca et al. JOURNAL OF BIOLOGICAL CHEMISTRY
- α-Synuclein-Induced Membrane Remodeling Is Driven by Binding Affinity, Partition Depth, and Interleaflet Order Asymmetry
- (2014) Anthony R. Braun et al. JOURNAL OF THE AMERICAN CHEMICAL SOCIETY
- Mass Spec Studio for Integrative Structural Biology
- (2014) Martial Rey et al. STRUCTURE
- Hydrogen/deuterium exchange mass spectrometry for probing higher order structure of protein therapeutics: methodology and applications
- (2013) Hui Wei et al. DRUG DISCOVERY TODAY
- Membrane Remodeling by α-Synuclein and Effects on Amyloid Formation
- (2013) Zhiping Jiang et al. JOURNAL OF THE AMERICAN CHEMICAL SOCIETY
- Optimized Phospholipid Bilayer Nanodiscs Facilitate High-Resolution Structure Determination of Membrane Proteins
- (2013) Franz Hagn et al. JOURNAL OF THE AMERICAN CHEMICAL SOCIETY
- Detergent-free mass spectrometry of membrane protein complexes
- (2013) Jonathan T S Hopper et al. NATURE METHODS
- Hydration dynamics as an intrinsic ruler for refining protein structure at lipid membrane interfaces
- (2013) C.-Y. Cheng et al. PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA
- -Synuclein in Parkinson's Disease
- (2013) L. Stefanis Cold Spring Harbor Perspectives in Medicine
- Native α-synuclein induces clustering of synaptic-vesicle mimics via binding to phospholipids and synaptobrevin-2/VAMP2
- (2013) Jiajie Diao et al. eLife
- Measuring Dynamics in Weakly Structured Regions of Proteins Using Microfluidics-Enabled Subsecond H/D Exchange Mass Spectrometry
- (2012) Tamanna Rob et al. ANALYTICAL CHEMISTRY
- Impact of N-Terminal Acetylation of α-Synuclein on Its Random Coil and Lipid Binding Properties
- (2012) Alexander S. Maltsev et al. BIOCHEMISTRY
- Depth of α-Synuclein in a Bilayer Determined by Fluorescence, Neutron Reflectometry, and Computation
- (2012) Candace M. Pfefferkorn et al. BIOPHYSICAL JOURNAL
- Remodeling of Lipid Vesicles into Cylindrical Micelles by α-Synuclein in an Extended α-Helical Conformation
- (2012) Naoko Mizuno et al. JOURNAL OF BIOLOGICAL CHEMISTRY
- The many faces of α-synuclein: from structure and toxicity to therapeutic target
- (2012) Hilal A. Lashuel et al. NATURE REVIEWS NEUROSCIENCE
- N-terminal acetylation of α-synuclein induces increased transient helical propensity and decreased aggregation rates in the intrinsically disordered monomer
- (2012) Lijuan Kang et al. PROTEIN SCIENCE
- Folding and misfolding of alpha-synuclein on membranes
- (2011) Igor Dikiy et al. BIOCHIMICA ET BIOPHYSICA ACTA-BIOMEMBRANES
- α-Synuclein misfolding and Parkinson's disease
- (2011) Leonid Breydo et al. BIOCHIMICA ET BIOPHYSICA ACTA-MOLECULAR BASIS OF DISEASE
- Structural Versatility of Bicellar Systems and Their Possibilities as Colloidal Carriers
- (2011) Barbosa-Barros Lucyanna et al. Pharmaceutics
- Conformational Analysis of Membrane Proteins in Phospholipid Bilayer Nanodiscs by Hydrogen Exchange Mass Spectrometry
- (2010) Christine M. Hebling et al. ANALYTICAL CHEMISTRY
- α-Synuclein: Membrane Interactions and Toxicity in Parkinson's Disease
- (2010) Pavan K. Auluck et al. Annual Review of Cell and Developmental Biology
- The N-Terminus of the Intrinsically Disordered Protein α-Synuclein Triggers Membrane Binding and Helix Folding
- (2010) Tim Bartels et al. BIOPHYSICAL JOURNAL
- Effects of Curvature and Composition on α-Synuclein Binding to Lipid Vesicles
- (2010) Elizabeth R. Middleton et al. BIOPHYSICAL JOURNAL
- Membrane Curvature Induction and Tubulation Are Common Features of Synucleins and Apolipoproteins
- (2010) Jobin Varkey et al. JOURNAL OF BIOLOGICAL CHEMISTRY
- ESIprot: a universal tool for charge state determination and molecular weight calculation of proteins from electrospray ionization mass spectrometry data
- (2010) Robert Winkler RAPID COMMUNICATIONS IN MASS SPECTROMETRY
- -Synuclein Promotes SNARE-Complex Assembly in Vivo and in Vitro
- (2010) J. Burre et al. SCIENCE
- Differential Phospholipid Binding of α-Synuclein Variants Implicated in Parkinson’s Disease Revealed by Solution NMR Spectroscopy
- (2009) Christina R. Bodner et al. BIOCHEMISTRY
- Biophysics of Parkinsons Disease: Structure and Aggregation of α- Synuclein
- (2009) Vladimir Uversky et al. CURRENT PROTEIN & PEPTIDE SCIENCE
- Multiple Tight Phospholipid-Binding Modes of α-Synuclein Revealed by Solution NMR Spectroscopy
- (2009) Christina R. Bodner et al. JOURNAL OF MOLECULAR BIOLOGY
- Interplay of -synuclein binding and conformational switching probed by single-molecule fluorescence
- (2009) A. C. M. Ferreon et al. PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA
- Intrinsically Disordered Proteins in Human Diseases: Introducing the D2 Concept
- (2008) Vladimir N. Uversky et al. Annual Review of Biophysics
- The two-fold aspect of the interplay of amyloidogenic proteins with lipid membranes
- (2008) Annalisa Relini et al. CHEMISTRY AND PHYSICS OF LIPIDS
- A versatile microfluidic chip for millisecond time-scale kinetic studies by electrospray mass spectrometry
- (2008) Tamanna Rob et al. JOURNAL OF THE AMERICAN SOCIETY FOR MASS SPECTROMETRY
- Folding and assembly of large macromolecular complexes monitored by hydrogen-deuterium exchange and mass spectrometry
- (2008) Bohumila Suchanova et al. Microbial Cell Factories
- Self-assembly of single integral membrane proteins into soluble nanoscale phospholipid bilayers
- (2003) Timothy H. Bayburt et al. PROTEIN SCIENCE
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