α-Synuclein: Membrane Interactions and Toxicity in Parkinson's Disease

α-Synuclein Delays Endoplasmic Reticulum (ER)-to-Golgi Transport in Mammalian Cells by Antagonizing ER/Golgi SNAREs

(2010) Nandhakumar Thayanidhi et al.   MOLECULAR BIOLOGY OF THE CELL

Increased Expression of α-Synuclein Reduces Neurotransmitter Release by Inhibiting Synaptic Vesicle Reclustering after Endocytosis

(2010) Venu M. Nemani et al.   NEURON

Coordination of Lipid Metabolism in Membrane Biogenesis

(2009) Axel Nohturfft et al.   Annual Review of Cell and Developmental Biology

Occupation and Risk of Parkinsonism

(2009) Caroline M. Tanner et al.   ARCHIVES OF NEUROLOGY

α-Synuclein Gene Rearrangements in Dominantly Inherited Parkinsonism

(2009) Pablo Ibáñez   ARCHIVES OF NEUROLOGY

Genomewide association study for onset age in Parkinson disease

(2009) Jeanne C Latourelle et al.   BMC Medical Genetics

Glucocerebrosidase mutations in clinical and pathologically proven Parkinson's disease

(2009) Juliane Neumann et al.   BRAIN

Update in the epidemiology of Parkinsonʼs disease

(2009) Alexis Elbaz et al.   CURRENT OPINION IN NEUROLOGY

Compounds from an unbiased chemical screen reverse both ER-to-Golgi trafficking defects and mitochondrial dysfunction in Parkinson's disease models

(2009) L. J. Su et al.   Disease Models & Mechanisms

LRRK2 enhances oxidative stress-induced neurotoxicity via its kinase activity

(2009) Hye Young Heo et al.   EXPERIMENTAL CELL RESEARCH

The Molecular Chaperone Hsp90 Modulates Intermediate Steps of Amyloid Assembly of the Parkinson-related Protein α-Synuclein

(2009) S. Fabio Falsone et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Conversion of Wild-type α-Synuclein into Mutant-type Fibrils and Its Propagation in the Presence of A30P Mutant

(2009) Motokuni Yonetani et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Curvature Dynamics of α-Synuclein Familial Parkinson Disease Mutants

(2009) Jason D. Perlmutter et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

E46K Parkinson’s-Linked Mutation Enhances C-Terminal-to-N-Terminal Contacts in α-Synuclein

(2009) Carla C. Rospigliosi et al.   JOURNAL OF MOLECULAR BIOLOGY

Welding Occupations and Mortality from Parkinson's Disease and Other Neurodegenerative Diseases Among United States Men, 1985–1999

(2009) Meir J. Stampfer   JOURNAL OF OCCUPATIONAL AND ENVIRONMENTAL HYGIENE

Parkinson's disease

(2009) Andrew J Lees et al.   LANCET

Neuropathological assessment of Parkinson's disease: refining the diagnostic criteria

(2009) Dennis W Dickson et al.   LANCET NEUROLOGY

α-Synuclein is part of a diverse and highly conserved interaction network that includes PARK9 and manganese toxicity

(2009) Aaron D Gitler et al.   NATURE GENETICS

Bridging high-throughput genetic and transcriptional data reveals cellular responses to alpha-synuclein toxicity

(2009) Esti Yeger-Lotem et al.   NATURE GENETICS

Genome-wide association study identifies common variants at four loci as genetic risk factors for Parkinson's disease

(2009) Wataru Satake et al.   NATURE GENETICS

Rab GTPases as coordinators of vesicle traffic

(2009) Harald Stenmark   NATURE REVIEWS MOLECULAR CELL BIOLOGY

A highly reproducible rotenone model of Parkinson's disease

(2009) Jason R. Cannon et al.   NEUROBIOLOGY OF DISEASE

Sphingosine Facilitates SNARE Complex Assembly and Activates Synaptic Vesicle Exocytosis

(2009) Frédéric Darios et al.   NEURON

Interplay between Cytosolic Dopamine, Calcium, and α-Synuclein Causes Selective Death of Substantia Nigra Neurons

(2009) Eugene V. Mosharov et al.   NEURON

Functional enhancement and protection of dopaminergic terminals by RAB3B overexpression

(2009) Chee Yeun Chung et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

An ER-Mitochondria Tethering Complex Revealed by a Synthetic Biology Screen

(2009) Benoît Kornmann et al.   SCIENCE

Yeast as a model for studying human neurodegenerative disorders

(2008) Leonor Miller-Fleming et al.   Biotechnology Journal

The Therapeutical Potential of Alpha-Synuclein Antiaggregatory Agents for Dementia with Lewy Bodies

(2008) Katrin Beyer et al.   CURRENT MEDICINAL CHEMISTRY

A systematic RNAi screen reveals involvement of endocytic pathway in neuronal dysfunction in α-synuclein transgenic C . elegans

(2008) Tomoki Kuwahara et al.   HUMAN MOLECULAR GENETICS

α-Synuclein–induced Aggregation of Cytoplasmic Vesicles in Saccharomyces cerevisiae

(2008) James H. Soper et al.   MOLECULAR BIOLOGY OF THE CELL

Low LDL cholesterol and increased risk of Parkinson's disease: Prospective results from Honolulu-Asia Aging Study

(2008) Xuemei Huang et al.   MOVEMENT DISORDERS

Mitofusin 2 tethers endoplasmic reticulum to mitochondria

(2008) Olga Martins de Brito et al.   NATURE

Mitochondrial Respiratory Dysfunction in Familiar Parkinsonism Associated with PINK1 Mutation

(2008) Claudia Piccoli et al.   NEUROCHEMICAL RESEARCH

Altered vesicular dopamine storage in Parkinson's disease: a premature demise

(2008) W. Michael Caudle et al.   TRENDS IN NEUROSCIENCES

Genomewide SNP assay reveals mutations underlying Parkinson disease

(2007) Javier Simon-Sanchez et al.   HUMAN MUTATION