标题
The metabolism-modulating activity of IL-17 signaling in health and disease
作者
关键词
-
出版物
JOURNAL OF EXPERIMENTAL MEDICINE
Volume 218, Issue 5, Pages -
出版商
Rockefeller University Press
发表日期
2021-04-07
DOI
10.1084/jem.20202191
参考文献
相关参考文献
注意：仅列出部分参考文献，下载原文获取全部文献信息。- Distinct metabolic programs established in the thymus control effector functions of γδ T cell subsets in tumor microenvironments
- (2021) Noella Lopes et al. NATURE IMMUNOLOGY
- Neutrophil Metabolic Shift during Their Lifecycle: Impact on Their Survival and Activation
- (2020) Louise Injarabian et al. INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES
- Interleukin-17 in rheumatoid arthritis: Trials and tribulations
- (2020) Leonie S. Taams JOURNAL OF EXPERIMENTAL MEDICINE
- γδ T cells and adipocyte IL-17RC control fat innervation and thermogenesis
- (2020) Bo Hu et al. NATURE
- CUX1 and IκBζ (NFKBIZ) mediate the synergistic inflammatory response to TNF and IL-17A in stromal fibroblasts
- (2020) Kamil Slowikowski et al. PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA
- Metabolic Adaptations to Infections at the Organismal Level
- (2020) Katia Troha et al. TRENDS IN IMMUNOLOGY
- Hyperproliferation is the main driver of metabolomic changes in psoriasis lesional skin
- (2020) Liis Pohla et al. Scientific Reports
- Insulin-Like Growth Factors Are Key Regulators of T Helper 17 Regulatory T Cell Balance in Autoimmunity
- (2020) Daniel DiToro et al. IMMUNITY
- Immunometabolism: From basic mechanisms to translation
- (2020) Liza Makowski et al. IMMUNOLOGICAL REVIEWS
- Circles of Life: linking metabolic and epigenetic cycles to immunity
- (2020) Chan‐Wang Jerry Lio et al. IMMUNOLOGY
- Tγδ17 cells build up the nerve
- (2020) Maria Ciofani NATURE IMMUNOLOGY
- Lymph node stromal cells: cartographers of the immune system
- (2020) Akshay T. Krishnamurty et al. NATURE IMMUNOLOGY
- Restoring synovial homeostasis in rheumatoid arthritis by targeting fibroblast-like synoviocytes
- (2020) Gyrid Nygaard et al. Nature Reviews Rheumatology
- The Cytokine IL-17A Limits Th17 Pathogenicity via a Negative Feedback Loop Driven by Autocrine Induction of IL-24
- (2020) Wai Po Chong et al. IMMUNITY
- Keratinocyte-Polyamines and Dendritic Cells: A Bad Duet for Psoriasis
- (2020) Mohna Bandyopadhyay et al. IMMUNITY
- Excessive Polyamine Generation in Keratinocytes Promotes Self-RNA Sensing by Dendritic Cells in Psoriasis
- (2020) Fangzhou Lou et al. IMMUNITY
- Structural cells are key regulators of organ-specific immune responses
- (2020) Thomas Krausgruber et al. NATURE
- The mesenchymal context in inflammation, immunity and cancer
- (2020) Vasiliki Koliaraki et al. NATURE IMMUNOLOGY
- Organ immune responses — don’t forget the structural cells
- (2020) Zewen Kelvin Tuong et al. Nature Reviews Nephrology
- Association Between Early Severe Cardiovascular Events and the Initiation of Treatment With the Anti–Interleukin 12/23p40 Antibody Ustekinumab
- (2020) Florence Poizeau et al. JAMA Dermatology
- An evolutionary perspective on immunometabolism
- (2019) Andrew Wang et al. SCIENCE
- The IL-17 Family of Cytokines in Health and Disease
- (2019) Mandy J. McGeachy et al. IMMUNITY
- Phosphorylation-dependent Regnase-1 release from endoplasmic reticulum is critical in IL-17 response
- (2019) Hiroki Tanaka et al. JOURNAL OF EXPERIMENTAL MEDICINE
- IL-17 metabolically reprograms activated fibroblastic reticular cells for proliferation and survival
- (2019) Saikat Majumder et al. NATURE IMMUNOLOGY
- IL-17 instructs lymphoid stromal cells
- (2019) Scott N. Mueller NATURE IMMUNOLOGY
- Cardiometabolic comorbidities in RA and PsA: lessons learned and future directions
- (2019) Lyn D. Ferguson et al. Nature Reviews Rheumatology
- Distinct immunocyte-promoting and adipocyte-generating stromal components coordinate adipose tissue immune and metabolic tenors
- (2019) Raul German Spallanzani et al. Science Immunology
- Systemic Lupus Erythematosus and Increased Prevalence of Atherosclerotic Cardiovascular Disease in Hospitalized Patients
- (2019) Gregory Katz et al. MAYO CLINIC PROCEEDINGS
- Targeting metabolic dysregulation for fibrosis therapy
- (2019) Xiao Zhao et al. NATURE REVIEWS DRUG DISCOVERY
- Fibroblast-Like Synoviocytes Glucose Metabolism as a Therapeutic Target in Rheumatoid Arthritis
- (2019) Patricia Gnieslaw de Oliveira et al. Frontiers in Immunology
- Dimethyl fumarate dampens IL-17-ACT1-TBK1 axis-mediated phosphorylation of Regnase-1 and suppresses IL-17–induced IκB-ζ expression
- (2019) Yui Ohgakiuchi et al. BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS
- The role of interleukin-17 in tumor development and progression
- (2019) Junjie Zhao et al. JOURNAL OF EXPERIMENTAL MEDICINE
- Targeting the interleukin-17 immune axis for cancer immunotherapy
- (2019) Gerardo A. Vitiello et al. JOURNAL OF EXPERIMENTAL MEDICINE
- Interleukin-17 cytokines: Effectors and targets in psoriasis—A breakthrough in understanding and treatment
- (2019) Immo Prinz et al. JOURNAL OF EXPERIMENTAL MEDICINE
- IL-17 receptor–based signaling and implications for disease
- (2019) Xiaoxia Li et al. NATURE IMMUNOLOGY
- An Integrated View of Immunometabolism
- (2018) Yun Sok Lee et al. CELL
- Dimethyl fumarate: targeting glycolysis to treat MS
- (2018) Stefano Angiari et al. CELL RESEARCH
- Psoriasis and the metabolic syndrome
- (2018) Paolo Gisondi et al. CLINICS IN DERMATOLOGY
- Cardiovascular disease in systemic lupus erythematosus
- (2018) Yudong Liu et al. CURRENT OPINION IN RHEUMATOLOGY
- Protection from Psoriasis-Related Thrombosis after Inhibition of IL-23 or IL-17A
- (2018) Yumeng Li et al. JOURNAL OF INVESTIGATIVE DERMATOLOGY
- High-Fat Diet Exacerbates Early Psoriatic Skin Inflammation Independent of Obesity: Saturated Fatty Acids as Key Players
- (2018) Diana Herbert et al. JOURNAL OF INVESTIGATIVE DERMATOLOGY
- IL-17-receptor-associated adaptor Act1 directly stabilizes mRNAs to mediate IL-17 inflammatory signaling
- (2018) Tomasz Herjan et al. NATURE IMMUNOLOGY
- γδ T cells producing interleukin-17A regulate adipose regulatory T cell homeostasis and thermogenesis
- (2018) Ayano C. Kohlgruber et al. NATURE IMMUNOLOGY
- Got my γδ17 T cells to keep me warm
- (2018) Pedro H. Papotto et al. NATURE IMMUNOLOGY
- Differential glucose requirement in skin homeostasis and injury identifies a therapeutic target for psoriasis
- (2018) Zhuzhen Zhang et al. NATURE MEDICINE
- Dimethyl fumarate targets GAPDH and aerobic glycolysis to modulate immunity
- (2018) Michael D. Kornberg et al. SCIENCE
- IL-23 and IL-1β Drive Human Th17 Cell Differentiation and Metabolic Reprogramming in Absence of CD28 Costimulation
- (2018) Shankar Revu et al. Cell Reports
- Hexokinase 2 as a novel selective metabolic target for rheumatoid arthritis
- (2018) Marta F Bustamante et al. ANNALS OF THE RHEUMATIC DISEASES
- Electrophilic properties of itaconate and derivatives regulate the IκBζ–ATF3 inflammatory axis
- (2018) Monika Bambouskova et al. NATURE
- Interleukin-17 Drives Interstitial Entrapment of Tissue Lipoproteins in Experimental Psoriasis
- (2018) Li-Hao Huang et al. Cell Metabolism
- New Advances in Adaptive Thermogenesis: UCP1 and Beyond
- (2018) Edward T. Chouchani et al. Cell Metabolism
- Targeting the interplay between metabolism and epigenetics in cancer
- (2018) Emilie Montellier et al. CURRENT OPINION IN ONCOLOGY
- IL-17R–EGFR axis links wound healing to tumorigenesis in Lrig1+ stem cells
- (2018) Xing Chen et al. JOURNAL OF EXPERIMENTAL MEDICINE
- IL-17 Receptor Signaling Negatively Regulates the Development of Tubulointerstitial Fibrosis in the Kidney
- (2018) Kritika Ramani et al. MEDIATORS OF INFLAMMATION
- IL-17 integrates multiple self-reinforcing, feed-forward mechanisms through the RNA binding protein Arid5a
- (2018) Nilesh Amatya et al. Science Signaling
- Foundations of Immunometabolism and Implications for Metabolic Health and Disease
- (2017) Gökhan S. Hotamisligil IMMUNITY
- IL-17A–Induced PLET1 Expression Contributes to Tissue Repair and Colon Tumorigenesis
- (2017) Jarod A. Zepp et al. JOURNAL OF IMMUNOLOGY
- IL-17 Receptor A Maintains and Protects the Skin Barrier To Prevent Allergic Skin Inflammation
- (2017) Achilleas Floudas et al. JOURNAL OF IMMUNOLOGY
- CNTO6785, a Fully Human Antiinterleukin 17 Monoclonal Antibody, in Patients with Rheumatoid Arthritis with Inadequate Response to Methotrexate: A Randomized, Placebo-controlled, Phase II, Dose-ranging Study
- (2017) Philip J. Mease et al. JOURNAL OF RHEUMATOLOGY
- Metabolic control of TH17 and induced Treg cell balance by an epigenetic mechanism
- (2017) Tao Xu et al. NATURE
- Inflammation, metaflammation and immunometabolic disorders
- (2017) Gökhan S. Hotamisligil NATURE
- Metabolic regulation of inflammation
- (2017) Timo Gaber et al. Nature Reviews Rheumatology
- Inflammation and metabolism in tissue repair and regeneration
- (2017) Sabine A. Eming et al. SCIENCE
- IL-17 Signaling: The Yin and the Yang
- (2017) Nilesh Amatya et al. TRENDS IN IMMUNOLOGY
- Interleukin 17 Family Cytokines: Signaling Mechanisms, Biological Activities, and Therapeutic Implications
- (2017) Leticia Monin et al. Cold Spring Harbor Perspectives in Biology
- IL-17-mediated mitochondrial dysfunction impairs apoptosis in rheumatoid arthritis synovial fibroblasts through activation of autophagy
- (2017) Eun Kyung Kim et al. Cell Death & Disease
- A Randomized, Double-Blind, Placebo-Controlled Phase 2 Study of Brodalumab in Patients With Moderate-to-Severe Crohn’s Disease
- (2016) Stephan R Targan et al. AMERICAN JOURNAL OF GASTROENTEROLOGY
- Dysregulated bioenergetics: a key regulator of joint inflammation
- (2016) M Biniecka et al. ANNALS OF THE RHEUMATIC DISEASES
- Exploration of candidate biomarkers for human psoriasis based on gas chromatography-mass spectrometry serum metabolomics
- (2016) H. Kang et al. BRITISH JOURNAL OF DERMATOLOGY
- IL-17 Receptor Signaling in Oral Epithelial Cells Is Critical for Protection against Oropharyngeal Candidiasis
- (2016) Heather R. Conti et al. Cell Host & Microbe
- The tryptophan metabolism enzyme L-kynureninase is a novel inflammatory factor in psoriasis and other inflammatory diseases
- (2016) Jamie L. Harden et al. JOURNAL OF ALLERGY AND CLINICAL IMMUNOLOGY
- MCPIP1/Regnase-1 Restricts IL-17A– and IL-17C–Dependent Skin Inflammation
- (2016) Leticia Monin et al. JOURNAL OF IMMUNOLOGY
- Interleukin-17 promotes prostate cancer via MMP7-induced epithelial-to-mesenchymal transition
- (2016) Q Zhang et al. ONCOGENE
- Transcriptome profiling unveils the role of cholesterol in IL-17A signaling in psoriasis
- (2016) Pallavi Varshney et al. Scientific Reports
- A Metabolic Switch for Th17 Pathogenicity
- (2015) Fred P. Davis et al. CELL
- Single-Cell Genomics Unveils Critical Regulators of Th17 Cell Pathogenicity
- (2015) Jellert T. Gaublomme et al. CELL
- CD5L/AIM Regulates Lipid Biosynthesis and Restrains Th17 Cell Pathogenicity
- (2015) Chao Wang et al. CELL
- Antigen- and Cytokine-Driven Accumulation of Regulatory T Cells in Visceral Adipose Tissue of Lean Mice
- (2015) Dmitriy Kolodin et al. Cell Metabolism
- Interleukin-23-Independent IL-17 Production Regulates Intestinal Epithelial Permeability
- (2015) Jacob S. Lee et al. IMMUNITY
- Growth Factor FGF2 Cooperates with Interleukin-17 to Repair Intestinal Epithelial Damage
- (2015) Xinyang Song et al. IMMUNITY
- Gut-Busters: IL-17 Ain’t Afraid of No IL-23
- (2015) Natasha Whibley et al. IMMUNITY
- MCPIP1 Endoribonuclease Activity Negatively Regulates Interleukin-17-Mediated Signaling and Inflammation
- (2015) Abhishek V. Garg et al. IMMUNITY
- A novel IL-17 signaling pathway controlling keratinocyte proliferation and tumorigenesis via the TRAF4–ERK5 axis
- (2015) Ling Wu et al. JOURNAL OF EXPERIMENTAL MEDICINE
- Immunometabolism governs dendritic cell and macrophage function
- (2015) Luke A.J. O’Neill et al. JOURNAL OF EXPERIMENTAL MEDICINE
- A Study to Evaluate the Safety, Tolerability, and Efficacy of Brodalumab in Subjects with Rheumatoid Arthritis and an Inadequate Response to Methotrexate
- (2015) K. Pavelka et al. JOURNAL OF RHEUMATOLOGY
- The transcriptional regulators IRF4, BATF and IL-33 orchestrate development and maintenance of adipose tissue–resident regulatory T cells
- (2015) Ajithkumar Vasanthakumar et al. NATURE IMMUNOLOGY
- IκBζ is a key driver in the development of psoriasis
- (2015) Claus Johansen et al. PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA
- Control of macrophage metabolism and activation by mTOR and Akt signaling
- (2015) Anthony J. Covarrubias et al. SEMINARS IN IMMUNOLOGY
- Enhanced meta-analysis and replication studies identify five new psoriasis susceptibility loci
- (2015) Lam C. Tsoi et al. Nature Communications
- Changes of serum cytokines-related Th1/Th2/Th17 concentration in patients with postmenopausal osteoporosis
- (2014) Jing Zhang et al. GYNECOLOGICAL ENDOCRINOLOGY
- Interleukin-17 Receptor A Signaling in Transformed Enterocytes Promotes Early Colorectal Tumorigenesis
- (2014) Kepeng Wang et al. IMMUNITY
- IL-17 Cuts to the Chase in Colon Cancer
- (2014) Matthias Ernst et al. IMMUNITY
- Metabolic programming and PDHK1 control CD4+ T cell subsets and inflammation
- (2014) Valerie A. Gerriets et al. JOURNAL OF CLINICAL INVESTIGATION
- IL-17A Enhances the Expression of Profibrotic Genes through Upregulation of the TGF-β Receptor on Hepatic Stellate Cells in a JNK-Dependent Manner
- (2014) Thomas Fabre et al. JOURNAL OF IMMUNOLOGY
- LC–MS Metabolomics of Psoriasis Patients Reveals Disease Severity-Dependent Increases in Circulating Amino Acids That Are Ameliorated by Anti-TNFα Treatment
- (2014) Muhammad Anas Kamleh et al. JOURNAL OF PROTEOME RESEARCH
- Metabolic reprogramming during TGFβ1-induced epithelial-to-mesenchymal transition
- (2014) L Jiang et al. ONCOGENE
- IL-17 drives psoriatic inflammation via distinct, target cell-specific mechanisms
- (2014) H.-L. Ha et al. PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA
- A Phase II Randomized Study of Subcutaneous Ixekizumab, an Anti-Interleukin-17 Monoclonal Antibody, in Rheumatoid Arthritis Patients Who Were Naive to Biologic Agents or Had an Inadequate Response to Tumor Necrosis Factor Inhibitors
- (2014) Mark C. Genovese et al. Arthritis & Rheumatology
- Inflammation and Mechanical Stretch Promote Aortic Stiffening in Hypertension Through Activation of p38 Mitogen-Activated Protein Kinase
- (2013) Jing Wu et al. CIRCULATION RESEARCH
- IL-17 inhibits adipogenesis in part via C/EBPα, PPARγ and Krüppel-like factors
- (2013) Mushtaq Ahmed et al. CYTOKINE
- Dendritic epidermal T cells regulate skin antimicrobial barrier function
- (2013) Amanda S. MacLeod et al. JOURNAL OF CLINICAL INVESTIGATION
- HuR Is Required for IL-17-Induced Act1-Mediated CXCL1 and CXCL5 mRNA Stabilization
- (2013) T. Herjan et al. JOURNAL OF IMMUNOLOGY
- TNFα and IL-17 cooperatively stimulate glucose metabolism and growth factor production in human colorectal cancer cells
- (2013) Daniel S Straus Molecular Cancer
- Fueling Immunity: Insights into Metabolism and Lymphocyte Function
- (2013) E. L. Pearce et al. SCIENCE
- Potential roles of interleukin-17A in the development of skin fibrosis in mice
- (2012) Yoshinobu Okamoto et al. ARTHRITIS AND RHEUMATISM
- Circulating levels of interleukin-17 and cardiovascular outcomes in patients with acute myocardial infarction
- (2012) Tabassome Simon et al. EUROPEAN HEART JOURNAL
- Interleukin-17 in atherosclerosis and cardiovascular disease: the good, the bad, and the unknown
- (2012) Giovanna Liuzzo et al. EUROPEAN HEART JOURNAL
- Secukinumab, a human anti-IL-17A monoclonal antibody, for moderate to severe Crohn's disease: unexpected results of a randomised, double-blind placebo-controlled trial
- (2012) Wolfgang Hueber et al. GUT
- Stromal and hematopoietic cells in secondary lymphoid organs: partners in immunity
- (2012) Deepali Malhotra et al. IMMUNOLOGICAL REVIEWS
- Mitochondrial mutagenesis correlates with the local inflammatory environment in arthritis
- (2011) Leonard C Harty et al. ANNALS OF THE RHEUMATIC DISEASES
- HIF1α–dependent glycolytic pathway orchestrates a metabolic checkpoint for the differentiation of TH17 and Tregcells
- (2011) Lewis Z. Shi et al. JOURNAL OF EXPERIMENTAL MEDICINE
- Blocking IL-17A Promotes the Resolution of Pulmonary Inflammation and Fibrosis Via TGF- 1-Dependent and -Independent Mechanisms
- (2011) S. Mi et al. JOURNAL OF IMMUNOLOGY
- Cutting Edge: Distinct Glycolytic and Lipid Oxidative Metabolic Programs Are Essential for Effector and Regulatory CD4+ T Cell Subsets
- (2011) R. D. Michalek et al. JOURNAL OF IMMUNOLOGY
- IL-17 in obesity and adipogenesis
- (2010) Mushtaq Ahmed et al. CYTOKINE & GROWTH FACTOR REVIEWS
- Inflammation and Colon Cancer
- (2010) Janoš Terzić et al. GASTROENTEROLOGY
- Induction of Neutrophil Gelatinase-associated Lipocalin Expression by Co-stimulation with Interleukin-17 and Tumor Necrosis Factor-α Is Controlled by IκB-ζ but neither by C/EBP-β nor C/EBP-δ
- (2010) Joachim R. Karlsen et al. JOURNAL OF BIOLOGICAL CHEMISTRY
- Bleomycin and IL-1β–mediated pulmonary fibrosis is IL-17A dependent
- (2010) Mark S. Wilson et al. JOURNAL OF EXPERIMENTAL MEDICINE
- Cutting Edge: Increased IL-17-Secreting T Cells in Children with New-Onset Type 1 Diabetes
- (2010) A. K. Marwaha et al. JOURNAL OF IMMUNOLOGY
- IL-17 Regulates Adipogenesis, Glucose Homeostasis, and Obesity
- (2010) L. A. Zuniga et al. JOURNAL OF IMMUNOLOGY
- Psoriasis and Systemic Inflammatory Diseases: Potential Mechanistic Links between Skin Disease and Co-Morbid Conditions
- (2010) Batya B. Davidovici et al. JOURNAL OF INVESTIGATIVE DERMATOLOGY
- Host responses to Candida albicans: Th17 cells and mucosal candidiasis
- (2010) Heather R. Conti et al. MICROBES AND INFECTION
- Interleukin-17A inhibits adipocyte differentiation in human mesenchymal stem cells and regulates pro-inflammatory responses in adipocytes
- (2009) Jennifer H. Shin et al. BIOCHEMICAL PHARMACOLOGY
- IL-17 stimulates the proliferation and differentiation of human mesenchymal stem cells: implications for bone remodeling
- (2009) H Huang et al. CELL DEATH AND DIFFERENTIATION
- Nephropathic complication of type-2 diabetes is following pattern of autoimmune diseases?
- (2009) Mohammad Kazemi Arababadi et al. DIABETES RESEARCH AND CLINICAL PRACTICE
- A bone-protective role for IL-17 receptor signaling in ovariectomy-induced bone loss
- (2009) Jaya Goswami et al. EUROPEAN JOURNAL OF IMMUNOLOGY
- Obesity predisposes to Th17 bias
- (2009) Shawn Winer et al. EUROPEAN JOURNAL OF IMMUNOLOGY
- Interleukin 17 Promotes Angiotensin II–Induced Hypertension and Vascular Dysfunction
- (2009) Meena S. Madhur et al. HYPERTENSION
- Differential Roles of Interleukin-17A and -17F in Host Defense against Mucoepithelial Bacterial Infection and Allergic Responses
- (2009) Harumichi Ishigame et al. IMMUNITY
- Th17 cells and IL-17 receptor signaling are essential for mucosal host defense against oral candidiasis
- (2009) Heather R. Conti et al. JOURNAL OF EXPERIMENTAL MEDICINE
- Loss of SOCS3 expression in T cells reveals a regulatory role for interleukin-17 in atherosclerosis
- (2009) Soraya Taleb et al. JOURNAL OF EXPERIMENTAL MEDICINE
- A protective function for interleukin 17A in T cell–mediated intestinal inflammation
- (2009) William O'Connor Jr et al. NATURE IMMUNOLOGY
- Lean, but not obese, fat is enriched for a unique population of regulatory T cells that affect metabolic parameters
- (2009) Markus Feuerer et al. NATURE MEDICINE
- IL-17 Receptor Signaling Inhibits C/EBP by Sequential Phosphorylation of the Regulatory 2 Domain
- (2009) F. Shen et al. Science Signaling
- Psoriasis and metabolic disease: epidemiology and pathophysiology
- (2008) Rahat S Azfar et al. CURRENT OPINION IN RHEUMATOLOGY
- Increased activity of interleukin-23/interleukin-17 proinflammatory axis in obese women
- (2008) M Sumarac-Dumanovic et al. INTERNATIONAL JOURNAL OF OBESITY
Discover Peeref hubs
Discuss science. Find collaborators. Network.
Join a conversationFind the ideal target journal for your manuscript
Explore over 38,000 international journals covering a vast array of academic fields.
Search