Functional monocytic myeloid-derived suppressor cells increase in blood but not airways and predict COVID-19 severity

Clinical features of patients infected with 2019 novel coronavirus in Wuhan, China

(2020) Chaolin Huang et al.   LANCET

SARS-CoV-2 Reverse Genetics Reveals a Variable Infection Gradient in the Respiratory Tract

(2020) Yixuan J. Hou et al.   CELL

SARS-CoV-2 Cell Entry Depends on ACE2 and TMPRSS2 and Is Blocked by a Clinically Proven Protease Inhibitor

(2020) Markus Hoffmann et al.   CELL

Complex Immune Dysregulation in COVID-19 Patients with Severe Respiratory Failure

(2020) Evangelos J. Giamarellos-Bourboulis et al.   Cell Host & Microbe

Comparison of Hospitalized Patients With ARDS Caused by COVID-19 and H1N1

(2020) Xiao Tang et al.   CHEST

Immunology of COVID-19: current state of the science

(2020) Nicolas Vabret et al.   IMMUNITY

Clinical and immunological features of severe and moderate coronavirus disease 2019

(2020) Guang Chen et al.   JOURNAL OF CLINICAL INVESTIGATION

Risk factors of critical & mortal COVID-19 cases: A systematic literature review and meta-analysis

(2020) Zhaohai Zheng et al.   JOURNAL OF INFECTION

Clinical course and risk factors for mortality of adult inpatients with COVID-19 in Wuhan, China: a retrospective cohort study

(2020) Fei Zhou et al.   LANCET

Pulmonary Vascular Endothelialitis, Thrombosis, and Angiogenesis in Covid-19

(2020) Maximilian Ackermann et al.   NEW ENGLAND JOURNAL OF MEDICINE

Risk Factors Associated With Acute Respiratory Distress Syndrome and Death in Patients With Coronavirus Disease 2019 Pneumonia in Wuhan, China

(2020) Chaomin Wu et al.   JAMA Internal Medicine

Severe COVID-19 is marked by a dysregulated myeloid cell compartment

(2020) Jonas Schulte-Schrepping et al.   CELL

Expansion of myeloid-derived suppressor cells in patients with severe coronavirus disease (COVID-19)

(2020) Chiara Agrati et al.   CELL DEATH AND DIFFERENTIATION

The clinical course and its correlated immune status in COVID-19 pneumonia

(2020) Ruyuan He et al.   JOURNAL OF CLINICAL VIROLOGY

Cytokine storm and leukocyte changes in mild versus severe SARS‐CoV‐2 infection: Review of 3939 COVID‐19 patients in China and emerging pathogenesis and therapy concepts

(2020) Jin Wang et al.   JOURNAL OF LEUKOCYTE BIOLOGY

Comparing SARS-CoV-2 with SARS-CoV and influenza pandemics

(2020) Eskild Petersen et al.   LANCET INFECTIOUS DISEASES

Severe immunosuppression and not a cytokine storm characterize COVID-19 infections

(2020) Kenneth E. Remy et al.   JCI Insight

Robust T Cell Immunity in Convalescent Individuals with Asymptomatic or Mild COVID-19

(2020) Takuya Sekine et al.   CELL

An inflammatory cytokine signature predicts COVID-19 severity and survival

(2020) Diane Marie Del Valle et al.   NATURE MEDICINE

Differential expansion of circulating human MDSC subsets in patients with cancer, infection and inflammation

(2020) Luca Cassetta et al.   Journal for ImmunoTherapy of Cancer

Human Blood and Tonsil Plasmacytoid Dendritic Cells Display Similar Gene Expression Profiles but Exhibit Differential Type I IFN Responses to Influenza A Virus Infection

(2019) Sindhu Vangeti et al.   JOURNAL OF IMMUNOLOGY

Deciphering myeloid-derived suppressor cells: isolation and markers in humans, mice and non-human primates

(2019) Luca Cassetta et al.   CANCER IMMUNOLOGY IMMUNOTHERAPY

How to measure the immunosuppressive activity of MDSC: assays, problems and potential solutions

(2018) Annika M. Bruger et al.   CANCER IMMUNOLOGY IMMUNOTHERAPY

Clinical relevance and suppressive capacity of human MDSC subsets

(2018) Stephan Lang et al.   CLINICAL CANCER RESEARCH

Plasticity of myeloid-derived suppressor cells in cancer

(2018) Evgenii Tcyganov et al.   CURRENT OPINION IN IMMUNOLOGY

Myeloid-Derived Suppressor Cells in Infection: A General Overview

(2018) Eva Medina et al.   Journal of Innate Immunity

The role of myeloid-derived suppressor cells (MDSC) in the inflammaging process

(2018) Antero Salminen et al.   AGEING RESEARCH REVIEWS

Effects of tumor grade and dexamethasone on myeloid cells in patients with glioma

(2018) Kara W Moyes et al.   OncoImmunology

Rhesus Macaque Myeloid-Derived Suppressor Cells Demonstrate T Cell Inhibitory Functions and Are Transiently Increased after Vaccination

(2017) Ang Lin et al.   JOURNAL OF IMMUNOLOGY

Flow Cytometric Analysis of Mononuclear Phagocytes in Nondiseased Human Lung and Lung-Draining Lymph Nodes

(2016) A. Nicole Desch et al.   AMERICAN JOURNAL OF RESPIRATORY AND CRITICAL CARE MEDICINE

Flow Cytometric Analysis of Myeloid Cells in Human Blood, Bronchoalveolar Lavage, and Lung Tissues

(2016) Yen-Rei A. Yu et al.   AMERICAN JOURNAL OF RESPIRATORY CELL AND MOLECULAR BIOLOGY

High-dose dexamethasone corrects impaired myeloid-derived suppressor cell function via Ets1 in immune thrombocytopenia

(2016) Y. Hou et al.   BLOOD

Dendritic Cells and Monocytes with Distinct Inflammatory Responses Reside in Lung Mucosa of Healthy Humans

(2016) Faezzah Baharom et al.   JOURNAL OF IMMUNOLOGY

The Nature of Myeloid-Derived Suppressor Cells in the Tumor Microenvironment

(2016) Vinit Kumar et al.   TRENDS IN IMMUNOLOGY

Recommendations for myeloid-derived suppressor cell nomenclature and characterization standards

(2016) Vincenzo Bronte et al.   Nature Communications

Effect of TLR Agonists on the Differentiation and Function of Human Monocytic Myeloid-Derived Suppressor Cells

(2015) Jing Wang et al.   JOURNAL OF IMMUNOLOGY

Mucosal Immune Responses Predict Clinical Outcomes during Influenza Infection Independently of Age and Viral Load

(2014) Christine M. Oshansky et al.   AMERICAN JOURNAL OF RESPIRATORY AND CRITICAL CARE MEDICINE

Myeloid-Derived Suppressor Cells Are Associated with Viral Persistence and Downregulation of TCR ζ Chain Expression on CD8+ T Cells in Chronic Hepatitis C Patients

(2014) Qing-Lei Zeng et al.   MOLECULES AND CELLS

Homogenous 96-Plex PEA Immunoassay Exhibiting High Sensitivity, Specificity, and Excellent Scalability

(2014) Erika Assarsson et al.   PLoS One

Myeloid-derived suppressor cell measurements in fresh and cryopreserved blood samples

(2012) Athanasios Kotsakis et al.   JOURNAL OF IMMUNOLOGICAL METHODS

Increased Myeloid-Derived Suppressor Cells in Gastric Cancer Correlate with Cancer Stage and Plasma S100A8/A9 Proinflammatory Proteins

(2012) L. Wang et al.   JOURNAL OF IMMUNOLOGY

HIF-1α regulates function and differentiation of myeloid-derived suppressor cells in the tumor microenvironment

(2010) Cesar A. Corzo et al.   JOURNAL OF EXPERIMENTAL MEDICINE

A Modified Sequential Organ Failure Assessment Score for Critical Care Triage

(2010) Colin K. Grissom et al.   Disaster Medicine and Public Health Preparedness

Arginase and pulmonary diseases

(2008) Harm Maarsingh et al.   NAUNYN-SCHMIEDEBERGS ARCHIVES OF PHARMACOLOGY