Neddylation stabilizes Nav1.1 to maintain interneuron excitability and prevent seizures in murine epilepsy models
出版年份 2021 全文链接
标题
Neddylation stabilizes Nav1.1 to maintain interneuron excitability and prevent seizures in murine epilepsy models
作者
关键词
-
出版物
JOURNAL OF CLINICAL INVESTIGATION
Volume 131, Issue 8, Pages -
出版商
American Society for Clinical Investigation
发表日期
2021-03-03
DOI
10.1172/jci136956
参考文献
相关参考文献
注意:仅列出部分参考文献,下载原文获取全部文献信息。- Neddylation is critical to cortical development by regulating Wnt/β-catenin signaling
- (2020) Lei Zhang et al. PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA
- Neuron–glia interactions in the pathophysiology of epilepsy
- (2019) Dipan C. Patel et al. NATURE REVIEWS NEUROSCIENCE
- dCas9-based Scn1a gene activation restores inhibitory interneuron excitability and attenuates seizures in Dravet syndrome mice
- (2019) Gaia Colasante et al. MOLECULAR THERAPY
- A mechanism in agrin signaling revealed by a prevalent Rapsyn mutation in congenital myasthenic syndrome
- (2019) Guanglin Xing et al. eLife
- PRRT2 controls neuronal excitability by negatively modulating Na+ channel 1.2/1.6 activity
- (2018) Floriana Fruscione et al. BRAIN
- Diagnostic outcomes for genetic testing of 70 genes in 8565 patients with epilepsy and neurodevelopmental disorders
- (2018) Amanda S. Lindy et al. EPILEPSIA
- Neddylation mediates ventricular chamber maturation through repression of Hippo signaling
- (2018) Jianqiu Zou et al. PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA
- Selective NaV1.1 activation rescues Dravet syndrome mice from seizures and premature death
- (2018) Kay L. Richards et al. PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA
- Deletion of KCNQ2/3 potassium channels from PV+ interneurons leads to homeostatic potentiation of excitatory transmission
- (2018) Heun Soh et al. eLife
- Activity-Dependent Gating of Parvalbumin Interneuron Function by the Perineuronal Net Protein Brevican
- (2017) Emilia Favuzzi et al. NEURON
- Transmembrane protein 108 is required for glutamatergic transmission in dentate gyrus
- (2017) Hui-Feng Jiao et al. PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA
- Seizing Control of KCC2: A New Therapeutic Target for Epilepsy
- (2017) Yvonne E. Moore et al. TRENDS IN NEUROSCIENCES
- Unaltered Network Activity and Interneuronal Firing During Spontaneous Cortical Dynamics In Vivo in a Mouse Model of Severe Myoclonic Epilepsy of Infancy
- (2016) Angela Michela De Stasi et al. CEREBRAL CORTEX
- Lrp4 in astrocytes modulates glutamatergic transmission
- (2016) Xiang-Dong Sun et al. NATURE NEUROSCIENCE
- Enzymatic Activity of the Scaffold Protein Rapsyn for Synapse Formation
- (2016) Lei Li et al. NEURON
- Dissecting the phenotypes of Dravet syndrome by gene deletion
- (2015) Moran Rubinstein et al. BRAIN
- Electroencephalographic features of patients with SCN1A-positive Dravet syndrome
- (2015) Hsiu-Fen Lee et al. BRAIN & DEVELOPMENT
- Amplicon Resequencing Identified Parental Mosaicism for Approximately 10% of “de novo”SCN1AMutations in Children with Dravet Syndrome
- (2015) Xiaojing Xu et al. HUMAN MUTATION
- Neddylation inhibition impairs spine development, destabilizes synapses and deteriorates cognition
- (2015) Annette M Vogl et al. NATURE NEUROSCIENCE
- Protein neddylation: beyond cullin–RING ligases
- (2015) Radoslav I. Enchev et al. NATURE REVIEWS MOLECULAR CELL BIOLOGY
- Relative contribution of TARPs γ-2 and γ-7 to cerebellar excitatory synaptic transmission and motor behavior
- (2015) Maya Yamazaki et al. PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA
- Tuning of fast-spiking interneuron properties by an activity-dependent transcriptional switch
- (2015) Nathalie Dehorter et al. SCIENCE
- Mutations in SLC12A5 in epilepsy of infancy with migrating focal seizures
- (2015) Tommy Stödberg et al. Nature Communications
- Targeting Neddylation Pathways to Inactivate Cullin-RING Ligases for Anticancer Therapy
- (2014) Yongchao Zhao et al. ANTIOXIDANTS & REDOX SIGNALING
- Impaired Action Potential Initiation in GABAergic Interneurons Causes Hyperexcitable Networks in an Epileptic Mouse Model Carrying a Human NaV1.1 Mutation
- (2014) U. B. S. Hedrich et al. JOURNAL OF NEUROSCIENCE
- Transcription of the Human Sodium Channel SCN1A Gene Is Repressed by a Scaffolding Protein RACK1
- (2014) Zhao-Fei Dong et al. MOLECULAR NEUROBIOLOGY
- Cation-chloride cotransporters in neuronal development, plasticity and disease
- (2014) Kai Kaila et al. NATURE REVIEWS NEUROSCIENCE
- Impaired excitability of somatostatin- and parvalbumin-expressing cortical interneurons in a mouse model of Dravet syndrome
- (2014) C. Tai et al. PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA
- Fast-spiking, parvalbumin+ GABAergic interneurons: From cellular design to microcircuit function
- (2014) H. Hu et al. SCIENCE
- Therapeutic potential of NaV1.1 activators
- (2014) Henrik S. Jensen et al. TRENDS IN PHARMACOLOGICAL SCIENCES
- Molecular identity of axonal sodium channels in human cortical pyramidal cells
- (2014) Cuiping Tian et al. Frontiers in Cellular Neuroscience
- Action Potential Initiation in Neocortical Inhibitory Interneurons
- (2014) Tun Li et al. PLOS BIOLOGY
- Broad Phenotypic Heterogeneity due to a Novel SCN1A Mutation in a Family With Genetic Epilepsy With Febrile Seizures Plus
- (2013) Hadassa Goldberg-Stern et al. JOURNAL OF CHILD NEUROLOGY
- Impact of inhibitory constraint of interneurons on neuronal excitability
- (2013) Vallent Lee et al. JOURNAL OF NEUROPHYSIOLOGY
- Parvalbumin-expressing basket-cell network plasticity induced by experience regulates adult learning
- (2013) Flavio Donato et al. NATURE
- HCN4 subunit expression in fast-spiking interneurons of the rat spinal cord and hippocampus
- (2013) D.I. Hughes et al. NEUROSCIENCE
- PRRT2 Mutations Cause Benign Familial Infantile Epilepsy and Infantile Convulsions with Choreoathetosis Syndrome
- (2012) Sarah E. Heron et al. AMERICAN JOURNAL OF HUMAN GENETICS
- Inhibitory Interneuron Deficit Links Altered Network Activity and Cognitive Dysfunction in Alzheimer Model
- (2012) Laure Verret et al. CELL
- Astrocyte dysfunction in temporal lobe epilepsy: K+ channels and gap junction coupling
- (2012) Christian Steinhäuser et al. GLIA
- NontruncatingSCN1AMutations Associated with Severe Myoclonic Epilepsy of Infancy Impair Cell Surface Expression
- (2012) Christopher H. Thompson et al. JOURNAL OF BIOLOGICAL CHEMISTRY
- Specific deletion of NaV1.1 sodium channels in inhibitory interneurons causes seizures and premature death in a mouse model of Dravet syndrome
- (2012) C. S. Cheah et al. PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA
- The developmental changes of Nav1.1 and Nav1.2 expression in the human hippocampus and temporal lobe
- (2011) Wenze Wang et al. BRAIN RESEARCH
- TARPs γ-2 and γ-7 are essential for AMPA receptor expression in the cerebellum
- (2010) Maya Yamazaki et al. EUROPEAN JOURNAL OF NEUROSCIENCE
- Altered Function of theSCN1AVoltage-gated Sodium Channel Leads to γ-Aminobutyric Acid-ergic (GABAergic) Interneuron Abnormalities
- (2010) Melinda S. Martin et al. JOURNAL OF BIOLOGICAL CHEMISTRY
- Hypoxia-inducible Factor α Subunit Stabilization by NEDD8 Conjugation Is Reactive Oxygen Species-dependent
- (2010) Ji-Hye Ryu et al. JOURNAL OF BIOLOGICAL CHEMISTRY
- Selective Reduction of Cholecystokinin-Positive Basket Cell Innervation in a Model of Temporal Lobe Epilepsy
- (2010) M. S. Wyeth et al. JOURNAL OF NEUROSCIENCE
- Isolation of Somatic Na+ Currents by Selective Inactivation of Axonal Channels with a Voltage Prepulse
- (2010) L. S. Milescu et al. JOURNAL OF NEUROSCIENCE
- NaV1.1 channels and epilepsy
- (2010) William A. Catterall et al. JOURNAL OF PHYSIOLOGY-LONDON
- Substrate-Assisted Inhibition of Ubiquitin-like Protein-Activating Enzymes: The NEDD8 E1 Inhibitor MLN4924 Forms a NEDD8-AMP Mimetic In Situ
- (2010) James E. Brownell et al. MOLECULAR CELL
- Mutational analysis of the SCN1A, SCN1B and GABRG2 genes in 150 Italian patients with idiopathic childhood epilepsies
- (2009) CLINICAL GENETICS
- Cell-Type-Dependent Molecular Composition of the Axon Initial Segment
- (2009) A. Lorincz et al. JOURNAL OF NEUROSCIENCE
- A Functional Null Mutation of SCN1B in a Patient with Dravet Syndrome
- (2009) G. A. Patino et al. JOURNAL OF NEUROSCIENCE
- FGF14 N-terminal splice variants differentially modulate Nav1.2 and Nav1.6-encoded sodium channels
- (2009) Fernanda Laezza et al. MOLECULAR AND CELLULAR NEUROSCIENCE
- Parvalbumin neurons and gamma rhythms enhance cortical circuit performance
- (2009) Vikaas S. Sohal et al. NATURE
- An inhibitor of NEDD8-activating enzyme as a new approach to treat cancer
- (2009) Teresa A. Soucy et al. NATURE
- Driving fast-spiking cells induces gamma rhythm and controls sensory responses
- (2009) Jessica A. Cardin et al. NATURE
- Origin and function of ubiquitin-like proteins
- (2009) Mark Hochstrasser NATURE
- A robust and high-throughput Cre reporting and characterization system for the whole mouse brain
- (2009) Linda Madisen et al. NATURE NEUROSCIENCE
- A BAC transgenic mouse model reveals neuron subtype-specific effects of a Generalized Epilepsy with Febrile Seizures Plus (GEFS+) mutation
- (2009) Bin Tang et al. NEUROBIOLOGY OF DISEASE
- Intracellular calcium modulation of voltage-gated sodium channels in ventricular myocytes
- (2008) Simona Casini et al. CARDIOVASCULAR RESEARCH
- Function and regulation of protein neddylation. ‘Protein Modifications: Beyond the Usual Suspects’ Review Series
- (2008) Gwénaël Rabut et al. EMBO REPORTS
- Ablation of Kv3.1 and Kv3.3 Potassium Channels Disrupts Thalamocortical Oscillations In Vitro and In Vivo
- (2008) F. Espinosa et al. JOURNAL OF NEUROSCIENCE
- Action potential generation requires a high sodium channel density in the axon initial segment
- (2008) Maarten H P Kole et al. NATURE NEUROSCIENCE
- FGF14 regulates the intrinsic excitability of cerebellar Purkinje neurons
- (2008) Vikram G. Shakkottai et al. NEUROBIOLOGY OF DISEASE
Become a Peeref-certified reviewer
The Peeref Institute provides free reviewer training that teaches the core competencies of the academic peer review process.
Get StartedAsk a Question. Answer a Question.
Quickly pose questions to the entire community. Debate answers and get clarity on the most important issues facing researchers.
Get Started