VPS13D bridges the ER to mitochondria and peroxisomes via Miro

VPS13D promotes peroxisome biogenesis

(2021) Heather A. Baldwin et al.   JOURNAL OF CELL BIOLOGY

Peroxisomal fission is modulated by the mitochondrial Rho‐GTPases, Miro1 and Miro2

(2020) Christian Covill‐Cooke et al.   EMBO REPORTS

A VPS13D spastic ataxia mutation disrupts the conserved adaptor-binding site in yeast Vps13

(2020) Samantha K Dziurdzik et al.   HUMAN MOLECULAR GENETICS

Cryo-EM reconstruction of a VPS13 fragment reveals a long groove to channel lipids between membranes

(2020) PeiQi Li et al.   JOURNAL OF CELL BIOLOGY

ER membranes exhibit phase behavior at sites of organelle contact

(2020) Christopher King et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Inter-organelle lipid transfer: a channel model for Vps13 and chorein-N motif proteins

(2020) Joshua A. Lees et al.   CURRENT OPINION IN CELL BIOLOGY

A High-Density Human Mitochondrial Proximity Interaction Network

(2020) Hana Antonicka et al.   Cell Metabolism

ER–mitochondria contacts promote mitochondrial-derived compartment biogenesis

(2020) Alyssa M. English et al.   JOURNAL OF CELL BIOLOGY

XK is a partner for VPS13A: a molecular link between Chorea-Acanthocytosis and McLeod Syndrome

(2020) Jae-Sook Park et al.   MOLECULAR BIOLOGY OF THE CELL

Role of VPS13, a protein with similarity to ATG2, in physiology and disease

(2020) Berrak Ugur et al.   CURRENT OPINION IN GENETICS & DEVELOPMENT

Lipid transporter TMEM24/C2CD2L is a Ca2+-regulated component of ER–plasma membrane contacts in mammalian neurons

(2019) Elizabeth Wen Sun et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Atg2 mediates direct lipid transfer between membranes for autophagosome formation

(2019) Takuo Osawa et al.   NATURE STRUCTURAL & MOLECULAR BIOLOGY

ATG2 transports lipids to promote autophagosome biogenesis

(2019) Diana P. Valverde et al.   JOURNAL OF CELL BIOLOGY

Human VPS13A is associated with multiple organelles and influences mitochondrial morphology and lipid droplet motility

(2019) Wondwossen M Yeshaw et al.   eLife

The autophagic membrane tether ATG2A transfers lipids between membranes

(2019) Shintaro Maeda et al.   eLife

Miro clusters regulate ER-mitochondria contact sites and link cristae organization to the mitochondrial transport machinery

(2019) Souvik Modi et al.   Nature Communications

Variants in Miro1 Cause Alterations of ER-Mitochondria Contact Sites in Fibroblasts from Parkinson’s Disease Patients

(2019) Clara Berenguer-Escuder et al.   Journal of Clinical Medicine

Recessive mutations in >VPS13D cause childhood onset movement disorders

(2018) Julie Gauthier et al.   ANNALS OF NEUROLOGY

Mutations in VPS13D lead to a new recessive ataxia with spasticity and mitochondrial defects

(2018) Eunju Seong et al.   ANNALS OF NEUROLOGY

Diagnostic exome sequencing in early-onset Parkinson's disease confirms VPS13C as a rare cause of autosomal-recessive Parkinson's disease

(2018) B. Schormair et al.   CLINICAL GENETICS

Vps13D Encodes a Ubiquitin-Binding Protein that Is Required for the Regulation of Mitochondrial Size and Clearance

(2018) Allyson L. Anding et al.   CURRENT BIOLOGY

Miro proteins coordinate microtubule‐ and actin‐dependent mitochondrial transport and distribution

(2018) Guillermo López‐Doménech et al.   EMBO JOURNAL

Competitive organelle-specific adaptors recruit Vps13 to membrane contact sites

(2018) Björn D.M. Bean et al.   JOURNAL OF CELL BIOLOGY

Identification of VAPA and VAPB as Kv2 channel-interacting proteins defining endoplasmic reticulum-plasma membrane junctions in mammalian brain neurons

(2018) Michael Kirmiz et al.   JOURNAL OF NEUROSCIENCE

Kv2 potassium channels form endoplasmic reticulum/plasma membrane junctions via interaction with VAPA and VAPB

(2018) Ben Johnson et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

A role for Mitochondrial Rho GTPase 1 (MIRO1) in motility and membrane dynamics of peroxisomes

(2018) Inês G. Castro et al.   TRAFFIC

An AP-MS- and BioID-compatible MAC-tag enables comprehensive mapping of protein interactions and subcellular localizations

(2018) Xiaonan Liu et al.   Nature Communications

Endosomal Rab cycles regulate Parkin-mediated mitophagy

(2018) Koji Yamano et al.   eLife

The peroxisome: an update on mysteries 2.0

(2018) Markus Islinger et al.   HISTOCHEMISTRY AND CELL BIOLOGY

Yeast peroxisomes: how are they formed and how do they grow?

(2018) Arman Akşit et al.   INTERNATIONAL JOURNAL OF BIOCHEMISTRY & CELL BIOLOGY

VPS13A and VPS13C are lipid transport proteins differentially localized at ER contact sites

(2018) Nikit Kumar et al.   JOURNAL OF CELL BIOLOGY

Identification of Miro1 and Miro2 as mitochondrial receptors for myosin XIX

(2018) Stefanie J. Oeding et al.   JOURNAL OF CELL SCIENCE

Lipid transfer proteins: the lipid commute via shuttles, bridges and tubes

(2018) Louise H. Wong et al.   NATURE REVIEWS MOLECULAR CELL BIOLOGY

Lipid exchange at ER-mitochondria contact sites: a puzzle falling into place with quite a few pieces missing

(2018) Carmelina Petrungaro et al.   CURRENT OPINION IN CELL BIOLOGY

Vps13-Mcp1 interact at vacuole–mitochondria interfaces and bypass ER–mitochondria contact sites

(2017) Arun T. John Peter et al.   JOURNAL OF CELL BIOLOGY

New splicing variants of mitochondrial Rho GTPase-1 (Miro1) transport peroxisomes

(2017) Kanji Okumoto et al.   JOURNAL OF CELL BIOLOGY

Proteomic mapping of cytosol-facing outer mitochondrial and ER membranes in living human cells by proximity biotinylation

(2017) Victoria Hung et al.   eLife

Loss of VPS13C Function in Autosomal-Recessive Parkinsonism Causes Mitochondrial Dysfunction and Increases PINK1/Parkin-Dependent Mitophagy

(2016) Suzanne Lesage et al.   AMERICAN JOURNAL OF HUMAN GENETICS

VAP, a Versatile Access Point for the Endoplasmic Reticulum: Review and analysis of FFAT-like motifs in the VAPome

(2016) Sarah E. Murphy et al.   BIOCHIMICA ET BIOPHYSICA ACTA-MOLECULAR AND CELL BIOLOGY OF LIPIDS

Endosome-ER Contacts Control Actin Nucleation and Retromer Function through VAP-Dependent Regulation of PI4P

(2016) Rui Dong et al.   CELL

Yeast Vps13 promotes mitochondrial function and is localized at membrane contact sites

(2016) Jae-Sook Park et al.   MOLECULAR BIOLOGY OF THE CELL

Miro phosphorylation sites regulate Parkin recruitment and mitochondrial motility

(2016) Evgeny Shlevkov et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

ER–mitochondrial junctions can be bypassed by dominant mutations in the endosomal protein Vps13

(2015) Alexander B. Lang et al.   JOURNAL OF CELL BIOLOGY

Gene essentiality and synthetic lethality in haploid human cells

(2015) V. A. Blomen et al.   SCIENCE

Identification and characterization of essential genes in the human genome

(2015) T. Wang et al.   SCIENCE

Mitotic redistribution of the mitochondrial network by Miro and Cenp-F

(2015) Gil Kanfer et al.   Nature Communications

Cohen Syndrome-associated Protein COH1 Physically and Functionally Interacts with the Small GTPase RAB6 at the Golgi Complex and Directs Neurite Outgrowth

(2014) Wenke Seifert et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Lysine 27 Ubiquitination of the Mitochondrial Transport Protein Miro Is Dependent on Serine 65 of the Parkin Ubiquitin Ligase

(2014) Nicol Birsa et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Bridging the gap: Membrane contact sites in signaling, metabolism, and organelle dynamics

(2014) William A. Prinz   JOURNAL OF CELL BIOLOGY

Loss of Miro1-directed mitochondrial movement results in a novel murine model for neuron disease

(2014) T. T. Nguyen et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Engineering an improved light-induced dimer (iLID) for controlling the localization and activity of signaling proteins

(2014) Gurkan Guntas et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Mitochondrial lipid transport at a glance

(2013) M. Scharwey et al.   JOURNAL OF CELL SCIENCE

PINK1 and Parkin Target Miro for Phosphorylation and Degradation to Arrest Mitochondrial Motility

(2011) Xinnan Wang et al.   CELL

Cohen Syndrome-associated Protein, COH1, Is a Novel, Giant Golgi Matrix Protein Required for Golgi Integrity

(2011) Wenke Seifert et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

The conserved GTPase Gem1 regulates endoplasmic reticulum-mitochondria connections

(2011) B. Kornmann et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

PINK1 Is Selectively Stabilized on Impaired Mitochondria to Activate Parkin

(2010) Derek P. Narendra et al.   PLOS BIOLOGY

The Mechanism of Ca2+-Dependent Regulation of Kinesin-Mediated Mitochondrial Motility

(2009) Xinnan Wang et al.   CELL

Miro1 Is a Calcium Sensor for Glutamate Receptor-Dependent Localization of Mitochondria at Synapses

(2009) Andrew F. MacAskill et al.   NEURON

An ER-Mitochondria Tethering Complex Revealed by a Synthetic Biology Screen

(2009) Benoît Kornmann et al.   SCIENCE

Nonvesicular phospholipid transfer between peroxisomes and the endoplasmic reticulum

(2008) S. Raychaudhuri et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Bidirectional Ca2+-dependent control of mitochondrial dynamics by the Miro GTPase

(2008) M. Saotome et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA