A VPS13D spastic ataxia mutation disrupts the conserved adaptor-binding site in yeast Vps13

Coming together to define membrane contact sites

(2019) Luca Scorrano et al.   Nature Communications

Human VPS13A is associated with multiple organelles and influences mitochondrial morphology and lipid droplet motility

(2019) Wondwossen M Yeshaw et al.   eLife

Comprehensive Analysis of Rare Variants of 101 Autism-Linked Genes in a Hungarian Cohort of Autism Spectrum Disorder Patients

(2019) Péter Balicza et al.   Frontiers in Genetics

SNAREs define targeting specificity of trafficking vesicles by combinatorial interaction with tethering factors

(2019) Seiichi Koike et al.   Nature Communications

Recessive mutations in >VPS13D cause childhood onset movement disorders

(2018) Julie Gauthier et al.   ANNALS OF NEUROLOGY

Mutations in VPS13D lead to a new recessive ataxia with spasticity and mitochondrial defects

(2018) Eunju Seong et al.   ANNALS OF NEUROLOGY

Vps13D Encodes a Ubiquitin-Binding Protein that Is Required for the Regulation of Mitochondrial Size and Clearance

(2018) Allyson L. Anding et al.   CURRENT BIOLOGY

Competitive organelle-specific adaptors recruit Vps13 to membrane contact sites

(2018) Björn D.M. Bean et al.   JOURNAL OF CELL BIOLOGY

VPS13A and VPS13C are lipid transport proteins differentially localized at ER contact sites

(2018) Nikit Kumar et al.   JOURNAL OF CELL BIOLOGY

Insights into autophagosome biogenesis from structural and biochemical analyses of the ATG2A-WIPI4 complex

(2018) Saikat Chowdhury et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

The Atg2-Atg18 complex tethers pre-autophagosomal membranes to the endoplasmic reticulum for autophagosome formation

(2018) Tetsuya Kotani et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

WD40 Repeat Proteins: Signalling Scaffold with Diverse Functions

(2018) Buddhi Prakash Jain et al.   PROTEIN JOURNAL

Here, there, and everywhere: The importance of ER membrane contact sites

(2018) Haoxi Wu et al.   SCIENCE

Differential requirement for ATG2A domains for localization to autophagic membranes and lipid droplets

(2017) Norito Tamura et al.   FEBS LETTERS

Amino acid substitution equivalent to human chorea-acanthocytosis I2771R in yeast Vps13 protein affects its binding to phosphatidylinositol 3-phosphate

(2017) Weronika Rzepnikowska et al.   HUMAN MOLECULAR GENETICS

Vps13-Mcp1 interact at vacuole–mitochondria interfaces and bypass ER–mitochondria contact sites

(2017) Arun T. John Peter et al.   JOURNAL OF CELL BIOLOGY

The Vps13p–Cdc31p complex is directly required for TGN late endosome transport and TGN homotypic fusion

(2017) Mithu De et al.   JOURNAL OF CELL BIOLOGY

Mitochondria-associated membranes as hubs for neurodegeneration

(2016) Michiel Krols et al.   ACTA NEUROPATHOLOGICA

Loss of VPS13C Function in Autosomal-Recessive Parkinsonism Causes Mitochondrial Dysfunction and Increases PINK1/Parkin-Dependent Mitophagy

(2016) Suzanne Lesage et al.   AMERICAN JOURNAL OF HUMAN GENETICS

Yeast Vps13 promotes mitochondrial function and is localized at membrane contact sites

(2016) Jae-Sook Park et al.   MOLECULAR BIOLOGY OF THE CELL

Using HHsearch to tackle proteins of unknown function: A pilot study with PH domains

(2016) David R. Fidler et al.   TRAFFIC

There's Something Wrong with my MAM; the ER–Mitochondria Axis and Neurodegenerative Diseases

(2016) Sebastien Paillusson et al.   TRENDS IN NEUROSCIENCES

ER–mitochondrial junctions can be bypassed by dominant mutations in the endosomal protein Vps13

(2015) Alexander B. Lang et al.   JOURNAL OF CELL BIOLOGY

The I-TASSER Suite: protein structure and function prediction

(2015) Jianyi Yang et al.   NATURE METHODS

Toward a Comprehensive Map of the Effectors of Rab GTPases

(2014) Alison K. Gillingham et al.   DEVELOPMENTAL CELL

Cohen Syndrome-associated Protein COH1 Physically and Functionally Interacts with the Small GTPase RAB6 at the Golgi Complex and Directs Neurite Outgrowth

(2014) Wenke Seifert et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Structure of Utp21 Tandem WD Domain Provides Insight into the Organization of the UTPB Complex Involved in Ribosome Synthesis

(2014) Cheng Zhang et al.   PLoS One

Crystal structure of EML1 reveals the basis for Hsp90 dependence of oncogenic EML4-ALK by disruption of an atypical  -propeller domain

(2014) M. W. Richards et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Computational design of a self-assembling symmetrical β-propeller protein

(2014) Arnout R. D. Voet et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

SPO71 Encodes a Developmental Stage-Specific Partner for Vps13 in Saccharomyces cerevisiae

(2013) Jae-Sook Park et al.   EUKARYOTIC CELL

Using Whole-Exome Sequencing to Identify Inherited Causes of Autism

(2013) Timothy W. Yu et al.   NEURON

Structure-based Analyses Reveal Distinct Binding Sites for Atg2 and Phosphoinositides in Atg18

(2012) Yasunori Watanabe et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

VPS13 regulates membrane morphogenesis during sporulation in Saccharomyces cerevisiae

(2012) Jae-Sook Park et al.   JOURNAL OF CELL SCIENCE

Two-Site Recognition of Phosphatidylinositol 3-Phosphate by PROPPINs in Autophagy

(2012) Sulochanadevi Baskaran et al.   MOLECULAR CELL

Fiji: an open-source platform for biological-image analysis

(2012) Johannes Schindelin et al.   NATURE METHODS

Identifying the Hotspots on the Top Faces of WD40-Repeat Proteins from Their Primary Sequences by β-Bulges and DHSW Tetrads

(2012) Xian-Hui Wu et al.   PLoS One

Cohen Syndrome-associated Protein, COH1, Is a Novel, Giant Golgi Matrix Protein Required for Golgi Integrity

(2011) Wenke Seifert et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Crystal Structure of Full-Length Apaf-1: How the Death Signal Is Relayed in the Mitochondrial Pathway of Apoptosis

(2011) Thomas Frank Reubold et al.   STRUCTURE

The many blades of the β-propeller proteins: conserved but versatile

(2011) Cammy K.-M. Chen et al.   TRENDS IN BIOCHEMICAL SCIENCES

Structure and function of WD40 domain proteins

(2011) Chao Xu et al.   Protein & Cell

Optimized Measurement Temperature Gives Access to the Solution Structure of a 49 kDa Homohexameric β-Propeller

(2010) Ilka Varnay et al.   JOURNAL OF THE AMERICAN CHEMICAL SOCIETY

Deletions in theVPS13B(COH1) gene as a cause of Cohen syndrome

(2009) I. Balikova et al.   HUMAN MUTATION