The tissue protective functions of interleukin-22 can be decoupled from pro-inflammatory actions through structure-based design
出版年份 2021 全文链接
标题
The tissue protective functions of interleukin-22 can be decoupled from pro-inflammatory actions through structure-based design
作者
关键词
cytokine, signaling, receptor, interleukin-22, STAT3, STAT1, inflammation, regeneration
出版物
IMMUNITY
Volume 54, Issue 4, Pages 660-672.e9
出版商
Elsevier BV
发表日期
2021-04-15
DOI
10.1016/j.immuni.2021.03.008
参考文献
相关参考文献
注意:仅列出部分参考文献,下载原文获取全部文献信息。- The development of colitis in Il10−/− mice is dependent on IL-22
- (2020) Dilini C. Gunasekera et al. Mucosal Immunology
- Fine-Tuning Cytokine Signals
- (2019) Jian-Xin Lin et al. Annual Review of Immunology
- Interleukin-22 protects intestinal stem cells against genotoxic stress
- (2019) Konrad Gronke et al. NATURE
- IL-10 Family Cytokines IL-10 and IL-22: from Basic Science to Clinical Translation
- (2019) Wenjun Ouyang et al. IMMUNITY
- Topological control of cytokine receptor signaling induces differential effects in hematopoiesis
- (2019) Kritika Mohan et al. SCIENCE
- IL-23–producing IL-10Rα–deficient gut macrophages elicit an IL-22–driven proinflammatory epithelial cell response
- (2019) Biana Bernshtein et al. Science Immunology
- Macromolecular structure determination using X-rays, neutrons and electrons: recent developments in Phenix
- (2019) Dorothee Liebschner et al. Acta Crystallographica Section D-Structural Biology
- Serum Amyloid A Proteins Induce Pathogenic Th17 Cells and Promote Inflammatory Disease
- (2019) June-Yong Lee et al. CELL
- Safety, pharmacokinetics, and biomarkers of F-652, a recombinant human interleukin-22 dimer, in healthy subjects
- (2018) Kai-Yang Tang et al. Cellular & Molecular Immunology
- Randomized phase 1 healthy volunteer study of UTTR1147A (IL-22Fc), a potential therapy for epithelial injury
- (2018) Michael E Rothenberg et al. CLINICAL PHARMACOLOGY & THERAPEUTICS
- Mechanisms of signalling and biased agonism in G protein-coupled receptors
- (2018) Denise Wootten et al. NATURE REVIEWS MOLECULAR CELL BIOLOGY
- The molecular details of cytokine signalling via the JAK/STAT pathway
- (2018) Rhiannon Morris et al. PROTEIN SCIENCE
- The IFN-λ-IFN-λR1-IL-10Rβ Complex Reveals Structural Features Underlying Type III IFN Functional Plasticity
- (2017) Juan L. Mendoza et al. IMMUNITY
- UCSF ChimeraX: Meeting modern challenges in visualization and analysis
- (2017) Thomas D. Goddard et al. PROTEIN SCIENCE
- An IL-23R/IL-22 Circuit Regulates Epithelial Serum Amyloid A to Promote Local Effector Th17 Responses
- (2016) Teruyuki Sano et al. CELL
- Interleukins (from IL-1 to IL-38), interferons, transforming growth factor β, and TNF-α: Receptors, functions, and roles in diseases
- (2016) Mübeccel Akdis et al. JOURNAL OF ALLERGY AND CLINICAL IMMUNOLOGY
- Engulfed cadherin fingers are polarized junctional structures between collectively migrating endothelial cells
- (2016) Arnold Hayer et al. NATURE CELL BIOLOGY
- Interleukin-22: Immunobiology and Pathology
- (2015) Jarrod A. Dudakov et al. Annual Review of Immunology
- Tuning Cytokine Receptor Signaling by Re-orienting Dimer Geometry with Surrogate Ligands
- (2015) Ignacio Moraga et al. CELL
- Assessing and maximizing data quality in macromolecular crystallography
- (2015) P Andrew Karplus et al. CURRENT OPINION IN STRUCTURAL BIOLOGY
- Interleukin-22 promotes intestinal-stem-cell-mediated epithelial regeneration
- (2015) Caroline A. Lindemans et al. NATURE
- Interferon-λ and interleukin 22 act synergistically for the induction of interferon-stimulated genes and control of rotavirus infection
- (2015) Pedro P Hernández et al. NATURE IMMUNOLOGY
- The role of IL-22 and Th22 cells in human skin diseases
- (2013) Hideki Fujita JOURNAL OF DERMATOLOGICAL SCIENCE
- Therapeutic opportunities of the IL-22–IL-22R1 system
- (2013) Robert Sabat et al. NATURE REVIEWS DRUG DISCOVERY
- Collaboration gets the most out of software
- (2013) Andrew Morin et al. eLife
- Pro-Inflammatory Signaling by IL-10 and IL-22: Bad Habit Stirred Up by Interferons?
- (2013) Heiko Mühl Frontiers in Immunology
- IFNα converts IL-22 into a cytokine efficiently activating STAT1 and its downstream targets
- (2012) Malte Bachmann et al. BIOCHEMICAL PHARMACOLOGY
- STAR: ultrafast universal RNA-seq aligner
- (2012) Alexander Dobin et al. BIOINFORMATICS
- Aryl Hydrocarbon Receptor Regulates Pancreatic IL-22 Production and Protects Mice From Acute Pancreatitis
- (2012) Jing Xue et al. GASTROENTEROLOGY
- Interleukin-22 Protects Intestinal Stem Cells from Immune-Mediated Tissue Damage and Regulates Sensitivity to Graft versus Host Disease
- (2012) Alan M. Hanash et al. IMMUNITY
- Th22 Cells Are an Important Source of IL-22 for Host Protection against Enteropathogenic Bacteria
- (2012) Rajatava Basu et al. IMMUNITY
- JAK and STAT Signaling Molecules in Immunoregulation and Immune-Mediated Disease
- (2012) John J. O'Shea et al. IMMUNITY
- Interleukin-22 Ameliorates Cerulein-Induced Pancreatitis in Mice by Inhibiting the Autophagic Pathway
- (2012) Dechun Feng et al. International Journal of Biological Sciences
- Interleukin-22 Drives Endogenous Thymic Regeneration in Mice
- (2012) J. A. Dudakov et al. SCIENCE
- An introduction to data reduction: space-group determination, scaling and intensity statistics
- (2011) Philip R. Evans ACTA CRYSTALLOGRAPHICA SECTION D-BIOLOGICAL CRYSTALLOGRAPHY
- Overview of theCCP4 suite and current developments
- (2011) Martyn D. Winn et al. ACTA CRYSTALLOGRAPHICA SECTION D-BIOLOGICAL CRYSTALLOGRAPHY
- MYC Phosphorylation, Activation, and Tumorigenic Potential in Hepatocellular Carcinoma Are Regulated by HMG-CoA Reductase
- (2011) Z. Cao et al. CANCER RESEARCH
- Structural Linkage between Ligand Discrimination and Receptor Activation by Type I Interferons
- (2011) Christoph Thomas et al. CELL
- Interpreting mixed signals: the cell's cytokine conundrum
- (2011) Greg M Delgoffe et al. CURRENT OPINION IN IMMUNOLOGY
- Border patrol: regulation of immunity, inflammation and tissue homeostasis at barrier surfaces by IL-22
- (2011) Gregory F Sonnenberg et al. NATURE IMMUNOLOGY
- XDS
- (2010) Wolfgang Kabsch ACTA CRYSTALLOGRAPHICA SECTION D-BIOLOGICAL CRYSTALLOGRAPHY
- Features and development ofCoot
- (2010) P. Emsley et al. ACTA CRYSTALLOGRAPHICA SECTION D-BIOLOGICAL CRYSTALLOGRAPHY
- PHENIX: a comprehensive Python-based system for macromolecular structure solution
- (2010) Paul D. Adams et al. ACTA CRYSTALLOGRAPHICA SECTION D-BIOLOGICAL CRYSTALLOGRAPHY
- CD4+ Lymphoid Tissue-Inducer Cells Promote Innate Immunity in the Gut
- (2010) Gregory F. Sonnenberg et al. IMMUNITY
- IL-22 Induces an Acute-Phase Response
- (2010) S. C. Liang et al. JOURNAL OF IMMUNOLOGY
- Structure and Mechanism of Receptor Sharing by the IL-10R2 Common Chain
- (2010) Sung-il Yoon et al. STRUCTURE
- New Activation Modus of STAT3
- (2009) Laure Dumoutier et al. JOURNAL OF BIOLOGICAL CHEMISTRY
- STAT3 links IL-22 signaling in intestinal epithelial cells to mucosal wound healing
- (2009) Geethanjali Pickert et al. JOURNAL OF EXPERIMENTAL MEDICINE
- Innate and Adaptive Interleukin-22 Protects Mice from Inflammatory Bowel Disease
- (2008) Lauren A. Zenewicz et al. IMMUNITY
- Cytokine Signaling Modules in Inflammatory Responses
- (2008) John J. O'Shea et al. IMMUNITY
- A human natural killer cell subset provides an innate source of IL-22 for mucosal immunity
- (2008) Marina Cella et al. NATURE
- Mapping and quantifying mammalian transcriptomes by RNA-Seq
- (2008) Ali Mortazavi et al. NATURE METHODS
- Ups and downs: The STAT1:STAT3 seesaw of Interferon and gp130 receptor signalling
- (2008) Gabriella Regis et al. SEMINARS IN CELL & DEVELOPMENTAL BIOLOGY
- Structure of IL-22 Bound to Its High-Affinity IL-22R1 Chain
- (2008) Brandi C. Jones et al. STRUCTURE
- Structural Biology of Shared Cytokine Receptors
- (2007) Xinquan Wang et al. Annual Review of Immunology
Publish scientific posters with Peeref
Peeref publishes scientific posters from all research disciplines. Our Diamond Open Access policy means free access to content and no publication fees for authors.
Learn MoreCreate your own webinar
Interested in hosting your own webinar? Check the schedule and propose your idea to the Peeref Content Team.
Create Now