Automated production of CCR5-negative CD4+-T cells in a GMP-compatible, clinical scale for treatment of HIV-positive patients
出版年份 2021 全文链接
标题
Automated production of CCR5-negative CD4+-T cells in a GMP-compatible, clinical scale for treatment of HIV-positive patients
作者
关键词
-
出版物
GENE THERAPY
Volume -, Issue -, Pages -
出版商
Springer Science and Business Media LLC
发表日期
2021-04-19
DOI
10.1038/s41434-021-00259-5
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注意:仅列出部分参考文献,下载原文获取全部文献信息。- Safe CRISPR/Cas9 inactivation of HIV-1 transcription with high specificity and broad-spectrum activity in latently infected cells by mutation of HIV-1 promoter NF-κB binding sites
- (2020) Cheng-Han Chung et al. Molecular Therapy-Nucleic Acids
- Automated Manufacture of Autologous CD19 CAR-T Cells for Treatment of Non-hodgkin Lymphoma
- (2020) Zachary Jackson et al. Frontiers in Immunology
- CAR T-cell therapy for cancer and HIV through novel approaches to HIV-associated haematological malignancies
- (2020) Blake J Rust et al. Lancet Haematology
- Challenges and Opportunities of Using Adoptive T-Cell Therapy as Part of an HIV Cure Strategy
- (2020) Yuqi Zhou et al. JOURNAL OF INFECTIOUS DISEASES
- HIV-1 remission following CCR5Δ32/Δ32 haematopoietic stem-cell transplantation
- (2019) Ravindra K. Gupta et al. NATURE
- CRISPR-Edited Stem Cells in a Patient with HIV and Acute Lymphocytic Leukemia
- (2019) Lei Xu et al. NEW ENGLAND JOURNAL OF MEDICINE
- GMP-Compliant Manufacturing of NKG2D CAR Memory T Cells Using CliniMACS Prodigy
- (2019) Lucía Fernández et al. Frontiers in Immunology
- Closed-system manufacturing of CD19 and dual-targeted CD20/19 chimeric antigen receptor T cells using the CliniMACS Prodigy device at an academic medical center
- (2018) Fenlu Zhu et al. CYTOTHERAPY
- Automated Manufacturing of Potent CD20-Directed Chimeric Antigen Receptor T Cells for Clinical Use
- (2017) Dominik Lock et al. HUMAN GENE THERAPY
- GMP-production of purified human B lymphocytes for the adoptive transfer in patients after allogeneic hematopoietic stem cell transplantation
- (2017) Hannes Tittlbach et al. Journal of Translational Medicine
- GMP-conformant on-site manufacturing of a CD133+ stem cell product for cardiovascular regeneration
- (2017) Anna Skorska et al. Stem Cell Research & Therapy
- Engineering hematopoietic stem cells toward a functional cure of human immunodeficiency virus infection
- (2016) Jianbin Wang et al. CYTOTHERAPY
- Automated manufacturing of chimeric antigen receptor T cells for adoptive immunotherapy using CliniMACS Prodigy
- (2016) Ulrike Mock et al. CYTOTHERAPY
- Automated Enrichment, Transduction, and Expansion of Clinical-Scale CD62L+T Cells for Manufacturing of Gene Therapy Medicinal Products
- (2016) Christoph Priesner et al. HUMAN GENE THERAPY
- Directed evolution of a recombinase that excises the provirus of most HIV-1 primary isolates with high specificity
- (2016) Janet Karpinski et al. NATURE BIOTECHNOLOGY
- Digital PCR to assess gene-editing frequencies (GEF-dPCR) mediated by designer nucleases
- (2016) Ulrike Mock et al. Nature Protocols
- Engineering T Cells to Functionally Cure HIV-1 Infection
- (2015) Rachel S Leibman et al. MOLECULAR THERAPY
- mRNA transfection of a novel TAL effector nuclease (TALEN) facilitates efficient knockout of HIV co-receptor CCR5
- (2015) U. Mock et al. NUCLEIC ACIDS RESEARCH
- TALEN-mediated editing of endogenous T-cell receptors facilitates efficient reprogramming of T lymphocytes by lentiviral gene transfer
- (2014) B Berdien et al. GENE THERAPY
- CD4 Ligation on Human Blood Monocytes Triggers Macrophage Differentiation and Enhances HIV Infection
- (2014) A. Zhen et al. JOURNAL OF VIROLOGY
- Gene Editing of CCR5 in Autologous CD4 T Cells of Persons Infected with HIV
- (2014) Pablo Tebas et al. NEW ENGLAND JOURNAL OF MEDICINE
- An online bioinformatics tool predicts zinc finger and TALE nuclease off-target cleavage
- (2014) Eli J. Fine et al. NUCLEIC ACIDS RESEARCH
- Multiplexing clonality: combining RGB marking and genetic barcoding
- (2014) Kerstin Cornils et al. NUCLEIC ACIDS RESEARCH
- High-Throughput Genome Editing and Phenotyping Facilitated by High Resolution Melting Curve Analysis
- (2014) Holly R. Thomas et al. PLoS One
- Novel lentiviral vectors with mutated reverse transcriptase for mRNA delivery of TALE nucleases
- (2014) Ulrike Mock et al. Scientific Reports
- TAL Effector-Nucleotide Targeter (TALE-NT) 2.0: tools for TAL effector design and target prediction
- (2012) Erin L. Doyle et al. NUCLEIC ACIDS RESEARCH
- Efficient Lentiviral Transduction and Transgene Expression in Primary Human B Cells
- (2012) Ulrike Mock et al. Human Gene Therapy Methods
- Lymphoid Tissue Damage in HIV-1 Infection Depletes Naïve T Cells and Limits T Cell Reconstitution after Antiretroviral Therapy
- (2012) Ming Zeng et al. PLoS Pathogens
- A novel TALE nuclease scaffold enables high genome editing activity in combination with low toxicity
- (2011) Claudio Mussolino et al. NUCLEIC ACIDS RESEARCH
- Long-Term Control of HIV byCCR5Delta32/Delta32 Stem-Cell Transplantation
- (2009) Gero Hütter et al. NEW ENGLAND JOURNAL OF MEDICINE
- Resistance of mature T cells to oncogene transformation
- (2008) S. Newrzela et al. BLOOD
- A Multicolor Panel of Novel Lentiviral “Gene Ontology” (LeGO) Vectors for Functional Gene Analysis
- (2008) Kristoffer Weber et al. MOLECULAR THERAPY
- Establishment of HIV-1 resistance in CD4+ T cells by genome editing using zinc-finger nucleases
- (2008) Elena E Perez et al. NATURE BIOTECHNOLOGY
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