Phase separation of the LINE-1 ORF1 protein is mediated by the N-terminus and coiled-coil domain
出版年份 2021 全文链接
标题
Phase separation of the LINE-1 ORF1 protein is mediated by the N-terminus and coiled-coil domain
作者
关键词
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出版物
BIOPHYSICAL JOURNAL
Volume -, Issue -, Pages -
出版商
Elsevier BV
发表日期
2021-03-31
DOI
10.1016/j.bpj.2021.03.028
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注意:仅列出部分参考文献,下载原文获取全部文献信息。- L1 drives IFN in senescent cells and promotes age-associated inflammation
- (2019) Marco De Cecco et al. NATURE
- LINE1 Derepression in Aged Wild-Type and SIRT6-Deficient Mice Drives Inflammation
- (2019) Matthew Simon et al. Cell Metabolism
- Considerations and Challenges in Studying Liquid-Liquid Phase Separation and Biomolecular Condensates
- (2019) Simon Alberti et al. CELL
- Comprehensive Scanning Mutagenesis of Human Retrotransposon LINE-1 Identifies Motifs Essential for Function
- (2019) Emily M. Adney et al. GENETICS
- The liquid nucleome – phase transitions in the nucleus at a glance
- (2019) Amy R. Strom et al. JOURNAL OF CELL SCIENCE
- Theories for Sequence-Dependent Phase Behaviors of Biomolecular Condensates
- (2018) Yi-Hsuan Lin et al. BIOCHEMISTRY
- Context-Dependent and Disease-Specific Diversity in Protein Interactions within Stress Granules
- (2018) Sebastian Markmiller et al. CELL
- A single N‐terminal phosphomimic disrupts TDP‐43 polymerization, phase separation, and RNA splicing
- (2018) Ailin Wang et al. EMBO JOURNAL
- High-Density Proximity Mapping Reveals the Subcellular Organization of mRNA-Associated Granules and Bodies
- (2018) Ji-Young Youn et al. MOLECULAR CELL
- Protein Phase Separation: A New Phase in Cell Biology
- (2018) Steven Boeynaems et al. TRENDS IN CELL BIOLOGY
- Human LINE-1 retrotransposition requires a metastable coiled coil and a positively charged N-terminus in L1ORF1p
- (2018) Elena Khazina et al. eLife
- Pi-Pi contacts are an overlooked protein feature relevant to phase separation
- (2018) Robert McCoy Vernon et al. eLife
- LINE-1 protein localization and functional dynamics during the cell cycle
- (2018) Paolo Mita et al. eLife
- Dissection of affinity captured LINE-1 macromolecular complexes
- (2018) Martin S Taylor et al. eLife
- Accurate Single-Sequence Prediction of Protein Intrinsic Disorder by an Ensemble of Deep Recurrent and Convolutional Architectures
- (2018) Jack Hanson et al. Journal of Chemical Information and Modeling
- P-Body Purification Reveals the Condensation of Repressed mRNA Regulons
- (2017) Arnaud Hubstenberger et al. MOLECULAR CELL
- Biomolecular condensates: organizers of cellular biochemistry
- (2017) Salman F. Banani et al. NATURE REVIEWS MOLECULAR CELL BIOLOGY
- Truncated ORF1 proteins can suppress LINE-1 retrotransposition in trans
- (2017) Mark Sokolowski et al. NUCLEIC ACIDS RESEARCH
- Structural and hydrodynamic properties of an intrinsically disordered region of a germ cell-specific protein on phase separation
- (2017) Jacob P. Brady et al. PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA
- Prediction of protein disorder based on IUPred
- (2017) Zsuzsanna Dosztányi PROTEIN SCIENCE
- ATPase-Modulated Stress Granules Contain a Diverse Proteome and Substructure
- (2016) Saumya Jain et al. CELL
- LINEs between Species: Evolutionary Dynamics of LINE-1 Retrotransposons across the Eukaryotic Tree of Life
- (2016) Atma M. Ivancevic et al. Genome Biology and Evolution
- L1Base 2: more retrotransposition-active LINE-1s, more mammalian genomes
- (2016) Tobias Penzkofer et al. NUCLEIC ACIDS RESEARCH
- ALS Mutations Disrupt Phase Separation Mediated by α-Helical Structure in the TDP-43 Low-Complexity C-Terminal Domain
- (2016) Alexander E. Conicella et al. STRUCTURE
- Roles for retrotransposon insertions in human disease
- (2016) Dustin C. Hancks et al. Mobile DNA
- Transposable elements become active and mobile in the genomes of aging mammalian somatic tissues
- (2016) Marco De Cecco et al. Aging-US
- The s2D Method: Simultaneous Sequence-Based Prediction of the Statistical Populations of Ordered and Disordered Regions in Proteins
- (2015) Pietro Sormanni et al. JOURNAL OF MOLECULAR BIOLOGY
- A 3′ Poly(A) Tract Is Required for LINE-1 Retrotransposition
- (2015) Aurélien J. Doucet et al. MOLECULAR CELL
- Residue-by-Residue View of In Vitro FUS Granules that Bind the C-Terminal Domain of RNA Polymerase II
- (2015) Kathleen A. Burke et al. MOLECULAR CELL
- Phase Transition of a Disordered Nuage Protein Generates Environmentally Responsive Membraneless Organelles
- (2015) Timothy J. Nott et al. MOLECULAR CELL
- Phosphorylation of ORF1p is required for L1 retrotransposition
- (2015) Pamela R. Cook et al. PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA
- Geroscience: Linking Aging to Chronic Disease
- (2014) Brian K. Kennedy et al. CELL
- Mobile DNA elements in the generation of diversity and complexity in the brain
- (2014) Jennifer A. Erwin et al. NATURE REVIEWS NEUROSCIENCE
- Genomes of replicatively senescent cells undergo global epigenetic changes leading to gene silencing and activation of transposable elements
- (2013) Marco De Cecco et al. AGING CELL
- Structure and properties of the esterase from non-LTR retrotransposons suggest a role for lipids in retrotransposition
- (2013) Anna M. Schneider et al. NUCLEIC ACIDS RESEARCH
- Acquisition of an Archaea-like ribonuclease H domain by plant L1 retrotransposons supports modular evolution
- (2013) G. Smyshlyaev et al. PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA
- Active Transposition in Genomes
- (2012) Cheng Ran Lisa Huang et al. Annual Review of Genetics
- Human Transposon Tectonics
- (2012) Kathleen H. Burns et al. CELL
- Active human retrotransposons: variation and disease
- (2012) Dustin C Hancks et al. CURRENT OPINION IN GENETICS & DEVELOPMENT
- Dynamic interactions between transposable elements and their hosts
- (2011) Henry L. Levin et al. NATURE REVIEWS GENETICS
- Trimeric structure and flexibility of the L1ORF1 protein in human L1 retrotransposition
- (2011) Elena Khazina et al. NATURE STRUCTURAL & MOLECULAR BIOLOGY
- Repetitive Elements May Comprise Over Two-Thirds of the Human Genome
- (2011) A. P. Jason de Koning et al. PLoS Genetics
- Enzymatic assembly of DNA molecules up to several hundred kilobases
- (2009) Daniel G Gibson et al. NATURE METHODS
- Non-LTR retrotransposons encode noncanonical RRM domains in their first open reading frame
- (2009) Elena Khazina et al. PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA
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