Truncated ORF1 proteins can suppress LINE-1 retrotransposition in trans

Involvement of Conserved Amino Acids in the C-Terminal Region of LINE-1 ORF2p in Retrotransposition

(2017) Claiborne M. Christian et al.   GENETICS

Involvement of Conserved Amino Acids in the C-Terminal Region of LINE-1 ORF2p in Retrotransposition

(2017) Claiborne M. Christian et al.   GENETICS

The Nucleotide Excision Repair Pathway Limits L1 Retrotransposition

(2016) Geraldine Servant et al.   GENETICS

Somatically Acquired LINE-1 Insertions in Normal Esophagus Undergo Clonal Expansion in Esophageal Squamous Cell Carcinoma

(2016) Tara T. Doucet-O'Hare et al.   HUMAN MUTATION

Conservation and Innovation of APOBEC3A Restriction Functions during Primate Evolution

(2016) Richard N. McLaughlin et al.   MOLECULAR BIOLOGY AND EVOLUTION

Identification of L1 ORF2p sequence important to retrotransposition using Bipartile Alu retrotransposition (BAR)

(2016) Claiborne M. Christian et al.   NUCLEIC ACIDS RESEARCH

The Nucleotide Excision Repair Pathway Limits L1 Retrotransposition

(2016) Geraldine Servant et al.   GENETICS

The endonuclease domain of the LINE-1 ORF2 protein can tolerate multiple mutations

(2016) Kristine J. Kines et al.   Mobile DNA

Primate-Specific ORF0 Contributes to Retrotransposon-Mediated Diversity

(2015) Ahmet M. Denli et al.   CELL

Retrotransposon insertions in the clonal evolution of pancreatic ductal adenocarcinoma

(2015) Nemanja Rodić et al.   NATURE MEDICINE

L1 retrotransposition requires rapid ORF1p oligomerization, a novel coiled coil-dependent property conserved despite extensive remodeling

(2015) M. Nabuan Naufer et al.   NUCLEIC ACIDS RESEARCH

Phosphorylation of ORF1p is required for L1 retrotransposition

(2015) Pamela R. Cook et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

LINE-1 expression and retrotransposition in Barrett’s esophagus and esophageal carcinoma

(2015) Tara T. Doucet-O'Hare et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

The Zinc-Finger Antiviral Protein ZAP Inhibits LINE and Alu Retrotransposition

(2015) John B. Moldovan et al.   PLoS Genetics

The Broad-Spectrum Antiviral Protein ZAP Restricts Human Retrotransposition

(2015) John L. Goodier et al.   PLoS Genetics

Long Interspersed Element-1 Protein Expression Is a Hallmark of Many Human Cancers

(2014) Nemanja Rodić et al.   AMERICAN JOURNAL OF PATHOLOGY

A Role for Retrotransposon LINE-1 in Fetal Oocyte Attrition in Mice

(2014) Safia Malki et al.   DEVELOPMENTAL CELL

Potential for genomic instability associated with retrotranspositionally-incompetent L1 loci

(2014) Kristine J. Kines et al.   NUCLEIC ACIDS RESEARCH

Regulation of L1 expression and retrotransposition by melatonin and its receptor: implications for cancer risk associated with light exposure at night

(2014) Dawn deHaro et al.   NUCLEIC ACIDS RESEARCH

Affinity Proteomics Reveals Human Host Factors Implicated in Discrete Stages of LINE-1 Retrotransposition

(2013) Martin S. Taylor et al.   CELL

Mapping the LINE1 ORF1 protein interactome reveals associated inhibitors of human retrotransposition

(2013) John L. Goodier et al.   NUCLEIC ACIDS RESEARCH

RNase L restricts the mobility of engineered retrotransposons in cultured human cells

(2013) Ao Zhang et al.   NUCLEIC ACIDS RESEARCH

Human LINE-1 restriction by APOBEC3C is deaminase independent and mediated by an ORF1p interaction that affects LINE reverse transcriptase activity

(2013) Axel V. Horn et al.   NUCLEIC ACIDS RESEARCH

Characterization of L1 ORF1p Self-Interaction and Cellular Localization Using a Mammalian Two-Hybrid System

(2013) Mark Sokolowski et al.   PLoS One

Prognostic value of LINE-1 retrotransposon expression and its subcellular localization in breast cancer

(2012) Long Chen et al.   BREAST CANCER RESEARCH AND TREATMENT

Molecular Reconstruction of Extinct LINE-1 Elements and Their Interaction with Nonautonomous Elements

(2012) Bradley J. Wagstaff et al.   MOLECULAR BIOLOGY AND EVOLUTION

MOV10 RNA Helicase Is a Potent Inhibitor of Retrotransposition in Cells

(2012) John L. Goodier et al.   PLoS Genetics

Importance of RNA analysis in interpretation of reporter gene expression data

(2011) Victoria P. Belancio   ANALYTICAL BIOCHEMISTRY

LINE-1 Elements in Structural Variation and Disease

(2011) Christine R. Beck et al.   Annual Review of Genomics and Human Genetics

Trimeric structure and flexibility of the L1ORF1 protein in human L1 retrotransposition

(2011) Elena Khazina et al.   NATURE STRUCTURAL & MOLECULAR BIOLOGY

Polymerization and nucleic acid-binding properties of human L1 ORF1 protein

(2011) Kathryn E. Callahan et al.   NUCLEIC ACIDS RESEARCH

Evolutionary Conservation of the Functional Modularity of Primate and Murine LINE-1 Elements

(2011) Bradley J. Wagstaff et al.   PLoS One

Nucleic acid chaperone properties of ORF1p from the non-LTR retrotransposon, LINE-1

(2011) Sandra L. Martin   RNA Biology

Characterization of a synthetic human LINE-1 retrotransposon ORFeus-Hs

(2011) Wenfeng An et al.   Mobile DNA

LINE-1 Retrotransposition Activity in Human Genomes

(2010) Christine R. Beck et al.   CELL

Mobile Interspersed Repeats Are Major Structural Variants in the Human Genome

(2010) Cheng Ran Lisa Huang et al.   CELL

Whole-genome resequencing allows detection of many rare LINE-1 insertion alleles in humans

(2010) A. D. Ewing et al.   GENOME RESEARCH

The impact of retrotransposons on human genome evolution

(2009) Richard Cordaux et al.   NATURE REVIEWS GENETICS

Many LINE1 elements contribute to the transcriptome of human somatic cells

(2009) Sanjida H Rangwala et al.   GENOME BIOLOGY

Mouse Maelstrom, a Component of Nuage, Is Essential for Spermatogenesis and Transposon Repression in Meiosis

(2008) Sarah F.C. Soper et al.   DEVELOPMENTAL CELL

The impact of multiple splice sites in human L1 elements

(2008) V.P. Belancio et al.   GENE

L1 mobile element expression causes multiple types of toxicity

(2008) Nicholas A. Wallace et al.   GENE

LINE-1 ORF1 protein enhances Alu SINE retrotransposition

(2008) Nicholas Wallace et al.   GENE

Mammalian non-LTR retrotransposons: For better or worse, in sickness and in health

(2008) V. P. Belancio et al.   GENOME RESEARCH