Isolation methodology is essential to the evaluation of the extracellular vesicle component of the senescence‐associated secretory phenotype

Cellular senescence contributes to age‐dependent changes in circulating extracellular vesicle cargo and function

(2020) Faisal J. Alibhai et al.   AGING CELL

Extracellular Vesicles Derived from Senescent Fibroblasts Attenuate the Dermal Effect on Keratinocyte Differentiation

(2020) Eun-Jeong Choi et al.   INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES

Increased production of functional small extracellular vesicles in senescent endothelial cells

(2020) Jaime A. Riquelme et al.   JOURNAL OF CELLULAR AND MOLECULAR MEDICINE

A proteomic atlas of senescence-associated secretomes for aging biomarker development

(2020) Nathan Basisty et al.   PLOS BIOLOGY

Small extracellular vesicles deliver miR-21 and miR-217 as pro-senescence effectors to endothelial cells

(2020) Emanuela Mensà et al.   Journal of Extracellular Vesicles

The Bright and Dark Side of Extracellular Vesicles in the Senescence-Associated Secretory Phenotype

(2020) Ryan Wallis et al.   MECHANISMS OF AGEING AND DEVELOPMENT

Excessive Cell Growth Causes Cytoplasm Dilution And Contributes to Senescence

(2019) Gabriel E. Neurohr et al.   CELL

Small Extracellular Vesicles Are Key Regulators of Non-cell Autonomous Intercellular Communication in Senescence via the Interferon Protein IFITM3

(2019) Michela Borghesan et al.   Cell Reports

The innate immune sensor Toll-like receptor 2 controls the senescence-associated secretory phenotype

(2019) Priya Hari et al.   Science Advances

Extracellular vesicles or exosomes? On primacy, precision, and popularity influencing a choice of nomenclature

(2019) Kenneth W. Witwer et al.   Journal of Extracellular Vesicles

Cellular Senescence: Defining a Path Forward

(2019) Vassilis Gorgoulis et al.   CELL

Emerging roles of extracellular vesicles in cellular senescence and aging

(2018) Masaki Takasugi   AGING CELL

Small extracellular vesicles and their miRNA cargo are anti-apoptotic members of the senescence-associated secretory phenotype

(2018) Lucia Terlecki-Zaniewicz et al.   Aging-US

Senolytics improve physical function and increase lifespan in old age

(2018) Ming Xu et al.   NATURE MEDICINE

Shedding light on the cell biology of extracellular vesicles

(2018) Guillaume van Niel et al.   NATURE REVIEWS MOLECULAR CELL BIOLOGY

EV-TRACK: transparent reporting and centralizing knowledge in extracellular vesicle research

(2017) Jan Van Deun et al.   NATURE METHODS

Small extracellular vesicles secreted from senescent cells promote cancer cell proliferation through EphA2

(2017) Masaki Takasugi et al.   Nature Communications

Cellular senescence drives age-dependent hepatic steatosis

(2017) Mikolaj Ogrodnik et al.   Nature Communications

Exosomes maintain cellular homeostasis by excreting harmful DNA from cells

(2017) Akiko Takahashi et al.   Nature Communications

Protein and chemotherapy profiling of extracellular vesicles harvested from therapeutic induced senescent triple negative breast cancer cells

(2017) E L Kavanagh et al.   Oncogenesis

Communication by Extracellular Vesicles: Where We Are and Where We Need to Go

(2016) Mercedes Tkach et al.   CELL

Naturally occurring p16Ink4a-positive cells shorten healthy lifespan

(2016) Darren J. Baker et al.   NATURE

NOTCH1 mediates a switch between two distinct secretomes during senescence

(2016) Matthew Hoare et al.   NATURE CELL BIOLOGY

Proteomic comparison defines novel markers to characterize heterogeneous populations of extracellular vesicle subtypes

(2016) Joanna Kowal et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Senescent intimal foam cells are deleterious at all stages of atherosclerosis

(2016) B. G. Childs et al.   SCIENCE

Cell-based screen for altered nuclear phenotypes reveals senescence progression in polyploid cells after Aurora kinase B inhibition

(2015) Mahito Sadaie et al.   MOLECULAR BIOLOGY OF THE CELL

Biogenesis, Secretion, and Intercellular Interactions of Exosomes and Other Extracellular Vesicles

(2014) Marina Colombo et al.   Annual Review of Cell and Developmental Biology

Cellular senescence: from physiology to pathology

(2014) Daniel Muñoz-Espín et al.   NATURE REVIEWS MOLECULAR CELL BIOLOGY

A screen for morphological complexity identifies regulators of switch-like transitions between discrete cell shapes

(2013) Zheng Yin et al.   NATURE CELL BIOLOGY

A complex secretory program orchestrated by the inflammasome controls paracrine senescence

(2013) Juan Carlos Acosta et al.   NATURE CELL BIOLOGY

The Senescence-Associated Secretory Phenotype: The Dark Side of Tumor Suppression

(2010) Jean-Philippe Coppé et al.   Annual Review of Pathology-Mechanisms of Disease

New biomarkers probing depth of cell senescence assessed by laser scanning cytometry

(2010) Hong Zhao et al.   CYTOMETRY PART A

A comparative analysis of the cell biology of senescence and aging

(2009) Eun Seong Hwang et al.   CELLULAR AND MOLECULAR LIFE SCIENCES

Senescence-Associated Secretory Phenotypes Reveal Cell-Nonautonomous Functions of Oncogenic RAS and the p53 Tumor Suppressor

(2008) Jean-Philippe Coppé et al.   PLOS BIOLOGY