标题
Advances in Modeling the Immune Microenvironment of Colorectal Cancer
作者
关键词
-
出版物
Frontiers in Immunology
Volume 11, Issue -, Pages -
出版商
Frontiers Media SA
发表日期
2021-02-10
DOI
10.3389/fimmu.2020.614300
参考文献
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注意:仅列出部分参考文献,下载原文获取全部文献信息。- Comparison of the molecular and cellular phenotypes of common mouse syngeneic models with human tumors
- (2020) Wenyan Zhong et al. BMC GENOMICS
- Colorectal cancer statistics, 2020
- (2020) Rebecca L. Siegel et al. CA-A CANCER JOURNAL FOR CLINICIANS
- Applications of patient-derived tumor xenograft models and tumor organoids
- (2020) Go J. Yoshida Journal of Hematology & Oncology
- Preclinical murine tumor models: a structural and functional perspective
- (2020) Marion V Guerin et al. eLife
- Mouse models of colorectal cancer: Past, present and future perspectives
- (2020) Florian Bürtin et al. WORLD JOURNAL OF GASTROENTEROLOGY
- Simulating the human colorectal cancer microenvironment in 3D tumor-stroma co-cultures in vitro and in vivo
- (2020) Mahesh Devarasetty et al. Scientific Reports
- Organs-on-chips: into the next decade
- (2020) Lucie A. Low et al. NATURE REVIEWS DRUG DISCOVERY
- SOSTDC1 promotes invasion and liver metastasis in colorectal cancer via interaction with ALCAM/CD166
- (2020) Rubén A. Bartolomé et al. ONCOGENE
- Cocultures of human colorectal tumor spheroids with immune cells reveal the therapeutic potential of MICA/B and NKG2A targeting for cancer treatment
- (2019) Tristan Courau et al. Journal for ImmunoTherapy of Cancer
- Characterization of immune responses to anti-PD-1 mono and combination immunotherapy in hematopoietic humanized mice implanted with tumor xenografts
- (2019) A. Capasso et al. Journal for ImmunoTherapy of Cancer
- Immunotherapy in colorectal cancer: rationale, challenges and potential
- (2019) Karuna Ganesh et al. Nature Reviews Gastroenterology & Hepatology
- Randomly distributed K14+ breast tumor cells polarize to the leading edge to direct collective migration in response to chemical and mechanical environmental cues
- (2019) Gregory D Longmore et al. CANCER RESEARCH
- 3D model for CAR‐mediated cytotoxicity using patient‐derived colorectal cancer organoids
- (2019) Theresa E Schnalzger et al. EMBO JOURNAL
- Crosstalk between cancer cells and tumor associated macrophages is required for mesenchymal circulating tumor cell-mediated colorectal cancer metastasis
- (2019) Chen Wei et al. Molecular Cancer
- Short-term 3D culture systems of various complexity for treatment optimization of colorectal carcinoma
- (2019) Marloes Zoetemelk et al. Scientific Reports
- Colorectal tumor-on-a-chip system: A 3D tool for precision onco-nanomedicine
- (2019) M. R. Carvalho et al. Science Advances
- Immunotherapy in colorectal cancer: Available clinical evidence, challenges and novel approaches
- (2019) Joseph Tintelnot et al. WORLD JOURNAL OF GASTROENTEROLOGY
- Colorectal cancer
- (2019) Evelien Dekker et al. LANCET
- Human Induced Pluripotent Stem-Cardiac-Endothelial-Tumor-on-a-Chip to Assess Anticancer Efficacy and Cardiotoxicity
- (2019) Kuo-Chan Weng et al. TISSUE ENGINEERING PART C-METHODS
- Durable Clinical Benefit With Nivolumab Plus Ipilimumab in DNA Mismatch Repair–Deficient/Microsatellite Instability–High Metastatic Colorectal Cancer
- (2018) Michael J. Overman et al. JOURNAL OF CLINICAL ONCOLOGY
- In Vitro Killing of Colorectal Carcinoma Cells by Autologous Activated NK Cells is Boosted by Anti-Epidermal Growth Factor Receptor-induced ADCC Regardless of RAS Mutation Status
- (2018) Ilaria Turin et al. JOURNAL OF IMMUNOTHERAPY
- International validation of the consensus Immunoscore for the classification of colon cancer: a prognostic and accuracy study
- (2018) Franck Pagès et al. LANCET
- TGFβ drives immune evasion in genetically reconstituted colon cancer metastasis
- (2018) Daniele V. F. Tauriello et al. NATURE
- Understanding the tumor immune microenvironment (TIME) for effective therapy
- (2018) Mikhail Binnewies et al. NATURE MEDICINE
- The path to metastatic mouse models of colorectal cancer
- (2018) Gabriele Romano et al. ONCOGENE
- Generation of Tumor-Reactive T Cells by Co-culture of Peripheral Blood Lymphocytes and Tumor Organoids
- (2018) Krijn K. Dijkstra et al. CELL
- 3D microfluidic ex vivo culture of organotypic tumor spheroids to model immune checkpoint blockade
- (2018) Amir R. Aref et al. LAB ON A CHIP
- Applications of tumor chip technology
- (2018) Stephanie J. Hachey et al. LAB ON A CHIP
- Human mast cells promote colon cancer growth via bidirectional crosstalk: studies in 2D and 3D coculture models
- (2018) Yingxin Yu et al. OncoImmunology
- Recruitment of CCR2+ tumor associated macrophage to sites of liver metastasis confers a poor prognosis in human colorectal cancer
- (2018) Julie G Grossman et al. OncoImmunology
- A multi-site metastasis-on-a-chip microphysiological system for assessing metastatic preference of cancer cells
- (2018) Julio Aleman et al. BIOTECHNOLOGY AND BIOENGINEERING
- Microfluidic device to attain high spatial and temporal control of oxygen
- (2018) Sandra F. Lam et al. PLoS One
- Ex Vivo Tumor-on-a-Chip Platforms to Study Intercellular Interactions within the Tumor Microenvironment
- (2018) Vardhman Kumar et al. Advanced Healthcare Materials
- OncogenicKrasdrives invasion and maintains metastases in colorectal cancer
- (2017) Adam T. Boutin et al. GENES & DEVELOPMENT
- Increased Infiltration of Natural Killer and T Cells in Colorectal Liver Metastases Improves Patient Overall Survival
- (2017) Matteo Donadon et al. JOURNAL OF GASTROINTESTINAL SURGERY
- Microfluidic modeling of the biophysical microenvironment in tumor cell invasion
- (2017) Yu Ling Huang et al. LAB ON A CHIP
- Modeling Physiological Events in 2D vs. 3D Cell Culture
- (2017) Kayla Duval et al. PHYSIOLOGY
- CDK4/6 Inhibition Augments Antitumor Immunity by Enhancing T-cell Activation
- (2017) Jiehui Deng et al. Cancer Discovery
- Ex Vivo Profiling of PD-1 Blockade Using Organotypic Tumor Spheroids
- (2017) Russell W. Jenkins et al. Cancer Discovery
- Three-Dimensional Cell Cultures in Drug Discovery and Development
- (2017) Ye Fang et al. SLAS Discovery
- 3D Microfluidic model for evaluating immunotherapy efficacy by tracking dendritic cell behaviour toward tumor cells
- (2017) Stefania Parlato et al. Scientific Reports
- Extracellular Matrix-dependent Pathways in Colorectal Cancer Cell Lines Reveal Potential Targets for Anticancer Therapies
- (2016) VAIDOTAS STANKEVICIUS et al. ANTICANCER RESEARCH
- 2D and 3D cell cultures – a comparison of different types of cancer cell cultures
- (2016) Marta Kapałczyńska et al. Archives of Medical Science
- A reductionist metastasis-on-a-chip platform for in vitro tumor progression modeling and drug screening
- (2016) Aleksander Skardal et al. BIOTECHNOLOGY AND BIOENGINEERING
- Three-dimensional perfused tumour spheroid model for anti-cancer drug screening
- (2016) Xiao Wan et al. BIOTECHNOLOGY LETTERS
- Humanized Mouse Xenograft Models: Narrowing the Tumor–Microenvironment Gap
- (2016) J. Jason Morton et al. CANCER RESEARCH
- Genetically engineered mouse models in oncology research and cancer medicine
- (2016) Kelly Kersten et al. EMBO Molecular Medicine
- Twist mediates an aggressive phenotype in human colorectal cancer cells
- (2016) JUN-JIAN DENG et al. INTERNATIONAL JOURNAL OF ONCOLOGY
- Co-Culture of Tumor Spheroids and Fibroblasts in a Collagen Matrix-Incorporated Microfluidic Chip Mimics Reciprocal Activation in Solid Tumor Microenvironment
- (2016) Su-Yeong Jeong et al. PLoS One
- Capturing tumor complexity in vitro: Comparative analysis of 2D and 3D tumor models for drug discovery
- (2016) Kristin Stock et al. Scientific Reports
- 3D microtumors in vitro supported by perfused vascular networks
- (2016) Agua Sobrino et al. Scientific Reports
- Bioreactor-engineered cancer tissue-like structures mimic phenotypes, gene expression profiles and drug resistance patterns observed “in vivo”
- (2015) Christian Hirt et al. BIOMATERIALS
- Nivolumab and Urelumab Enhance Antitumor Activity of Human T Lymphocytes Engrafted in Rag2-/-IL2R null Immunodeficient Mice
- (2015) M. F. Sanmamed et al. CANCER RESEARCH
- Evaluating Patient-Derived Colorectal Cancer Xenografts as Preclinical Models by Comparison with Patient Clinical Data
- (2015) M. Nunes et al. CANCER RESEARCH
- Engineering cancer microenvironments for in vitro 3-D tumor models
- (2015) Waseem Asghar et al. Materials Today
- IL6 Mediates Immune and Colorectal Cancer Cell Cross-talk via miR-21 and miR-29b
- (2015) S. A. A. Patel et al. MOLECULAR CANCER RESEARCH
- PD-1 Blockade in Tumors with Mismatch-Repair Deficiency
- (2015) Dung T. Le et al. NEW ENGLAND JOURNAL OF MEDICINE
- IGF2 is an actionable target that identifies a distinct subpopulation of colorectal cancer patients with marginal response to anti-EGFR therapies
- (2015) Eugenia R. Zanella et al. Science Translational Medicine
- HER2 Activating Mutations Are Targets for Colorectal Cancer Treatment
- (2015) S. M. Kavuri et al. Cancer Discovery
- Secreted Factors from Colorectal and Prostate Cancer Cells Skew the Immune Response in Opposite Directions
- (2015) Marie Lundholm et al. Scientific Reports
- Genetic Evidence That Intratumoral T-cell Proliferation and Activation Are Associated with Recurrence and Survival in Patients with Resected Colorectal Liver Metastases
- (2015) A. V. Maker et al. Cancer Immunology Research
- Low Infiltration of Peritumoral Regulatory T Cells Predicts Worse Outcome Following Resection of Colorectal Liver Metastases
- (2014) Kazuya Nakagawa et al. ANNALS OF SURGICAL ONCOLOGY
- Resveratrol-induced potentiation of the antitumor effects of oxaliplatin is accompanied by an altered cytokine profile of human monocyte-derived macrophages
- (2014) Bettina M. Kaminski et al. APOPTOSIS
- Three-Dimensional Cell Culture Systems and Their Applications in Drug Discovery and Cell-Based Biosensors
- (2014) Rasheena Edmondson et al. ASSAY AND DRUG DEVELOPMENT TECHNOLOGIES
- A strategy for integrating essential three-dimensional microphysiological systems of human organs for realistic anticancer drug screening
- (2014) Christopher Heylman et al. EXPERIMENTAL BIOLOGY AND MEDICINE
- FOXC2 promotes colorectal cancer metastasis by directly targeting MET
- (2014) Y-M Cui et al. ONCOGENE
- Fusobacterium nucleatum Potentiates Intestinal Tumorigenesis and Modulates the Tumor-Immune Microenvironment
- (2013) Aleksandar D. Kostic et al. Cell Host & Microbe
- Concomitant BRAF and PI3K/mTOR Blockade Is Required for Effective Treatment of BRAFV600E Colorectal Cancer
- (2013) E. M. Coffee et al. CLINICAL CANCER RESEARCH
- Crosstalk between colon cancer cells and macrophages via inflammatory mediators and CD47 promotes tumour cell migration
- (2013) Yuan Zhang et al. EUROPEAN JOURNAL OF CANCER
- AP4 is a mediator of epithelial–mesenchymal transition and metastasis in colorectal cancer
- (2013) Rene Jackstadt et al. JOURNAL OF EXPERIMENTAL MEDICINE
- A microfluidic platform for generating large-scale nearly identical human microphysiological vascularized tissue arrays
- (2013) Yu-Hsiang Hsu et al. LAB ON A CHIP
- Cadherin-17 interacts with α2β1 integrin to regulate cell proliferation and adhesion in colorectal cancer cells causing liver metastasis
- (2013) R A Bartolomé et al. ONCOGENE
- Epithelial–Mesenchymal Transition (EMT) Induced by TNF-α Requires AKT/GSK-3β-Mediated Stabilization of Snail in Colorectal Cancer
- (2013) Hao Wang et al. PLoS One
- Impact of the 3D Microenvironment on Phenotype, Gene Expression, and EGFR Inhibition of Colorectal Cancer Cell Lines
- (2013) Anna C. Luca et al. PLoS One
- Phenotypic Skewing of Macrophages In Vitro by Secreted Factors from Colorectal Cancer Cells
- (2013) Sofia Edin et al. PLoS One
- Amplification of the MET Receptor Drives Resistance to Anti-EGFR Therapies in Colorectal Cancer
- (2013) Alberto Bardelli et al. Cancer Discovery
- Loss of p53 in Enterocytes Generates an Inflammatory Microenvironment Enabling Invasion and Lymph Node Metastasis of Carcinogen-Induced Colorectal Tumors
- (2012) Sarah Schwitalla et al. CANCER CELL
- Hypoxia-Inducible Factors in Physiology and Medicine
- (2012) Gregg L. Semenza CELL
- The immune score as a new possible approach for the classification of cancer
- (2012) Jérôme Galon et al. Journal of Translational Medicine
- OCT4 regulates epithelial-mesenchymal transition and its knockdown inhibits colorectal cancer cell migration and invasion
- (2012) XINZHENG DAI et al. ONCOLOGY REPORTS
- Silencing SOX2 Induced Mesenchymal-Epithelial Transition and Its Expression Predicts Liver and Lymph Node Metastasis of CRC Patients
- (2012) Xu Han et al. PLoS One
- Overexpression of ZEB2 at the Invasion Front of Colorectal Cancer Is an Independent Prognostic Marker and Regulates Tumor Invasion In Vitro
- (2011) C. Kahlert et al. CLINICAL CANCER RESEARCH
- Ablative therapies for colorectal liver metastases: a systematic review
- (2011) S. Pathak et al. Colorectal Disease
- Histopathologic-Based Prognostic Factors of Colorectal Cancers Are Associated With the State of the Local Immune Reaction
- (2011) Bernhard Mlecnik et al. JOURNAL OF CLINICAL ONCOLOGY
- Current treatment for colorectal liver metastases
- (2011) Evangelos P Misiakos WORLD JOURNAL OF GASTROENTEROLOGY
- A Molecularly Annotated Platform of Patient-Derived Xenografts ("Xenopatients") Identifies HER2 as an Effective Therapeutic Target in Cetuximab-Resistant Colorectal Cancer
- (2011) A. Bertotti et al. Cancer Discovery
- The NLRP3 inflammasome functions as a negative regulator of tumorigenesis during colitis-associated cancer
- (2010) Irving C. Allen et al. JOURNAL OF EXPERIMENTAL MEDICINE
- The density of macrophages in the invasive front is inversely correlated to liver metastasis in colon cancer
- (2010) Qiang Zhou et al. Journal of Translational Medicine
- Development of a mouse model for sporadic and metastatic colon tumors and its use in assessing drug treatment
- (2010) K. E. Hung et al. PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA
- T Cell Infiltrate Predicts Long-Term Survival Following Resection of Colorectal Cancer Liver Metastases
- (2009) Steven C. Katz et al. ANNALS OF SURGICAL ONCOLOGY
- IL-6 and Stat3 Are Required for Survival of Intestinal Epithelial Cells and Development of Colitis-Associated Cancer
- (2009) Sergei Grivennikov et al. CANCER CELL
- A micro cell culture analog (µCCA) with 3-D hydrogel culture of multiple cell lines to assess metabolism-dependent cytotoxicity of anti-cancer drugs
- (2009) Jong Hwan Sung et al. LAB ON A CHIP
- Immune infiltration in human tumors: a prognostic factor that should not be ignored
- (2009) F Pagès et al. ONCOGENE
- The Innate Immune Receptor Nod1 Protects the Intestine from Inflammation-Induced Tumorigenesis
- (2008) G. Y. Chen et al. CANCER RESEARCH
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