A reductionist metastasis-on-a-chip platform for in vitro tumor progression modeling and drug screening

Engineered In Vitro Disease Models

(2015) Kambez H. Benam et al.   Annual Review of Pathology-Mechanisms of Disease

SNAIL-induced epithelial-to-mesenchymal transition produces concerted biophysical changes from altered cytoskeletal gene expression

(2015) Daniel J. McGrail et al.   FASEB JOURNAL

Organs-on-a-chip: a new tool for drug discovery

(2014) Alessandro Polini et al.   Expert Opinion on Drug Discovery

Standing the test of time: targeting thymidylate biosynthesis in cancer therapy

(2014) Peter M. Wilson et al.   Nature Reviews Clinical Oncology

Epithelial to mesenchymal transition inducing transcription factors and metastatic cancer

(2014) Mousumi Tania et al.   TUMOR BIOLOGY

Biomarkers of Residual Disease, Disseminated Tumor Cells, and Metastases in the MMTV-PyMT Breast Cancer Model

(2013) Christian Franci et al.   PLoS One

Tissue specific synthetic ECM hydrogels for 3-D in vitro maintenance of hepatocyte function

(2012) Aleksander Skardal et al.   BIOMATERIALS

Loss of cancer drug activity in colon cancer HCT-116 cells during spheroid formation in a new 3-D spheroid cell culture system

(2012) Henning Karlsson et al.   EXPERIMENTAL CELL RESEARCH

Evaluation of hydrogels for bio-printing applications

(2012) Sean V. Murphy et al.   JOURNAL OF BIOMEDICAL MATERIALS RESEARCH PART A

Hyaluronic Acid Hydrogels for Biomedical Applications

(2011) Jason A. Burdick et al.   ADVANCED MATERIALS

Three-dimensional culture of hepatocytes on porcine liver tissue-derived extracellular matrix

(2011) Ren Lang et al.   BIOMATERIALS

Towards automated production and drug sensitivity testing using scaffold-free spherical tumor microtissues

(2011) Maren Drewitz et al.   Biotechnology Journal

Hyaluronic acid-based clinical biomaterials derived for cell and molecule delivery in regenerative medicine

(2011) Glenn D. Prestwich   JOURNAL OF CONTROLLED RELEASE

Dynamically Crosslinked Gold Nanoparticle - Hyaluronan Hydrogels

(2010) Aleksander Skardal et al.   ADVANCED MATERIALS

Bioprinting vessel-like constructs using hyaluronan hydrogels crosslinked with tetrahedral polyethylene glycol tetracrylates

(2010) Aleksander Skardal et al.   BIOMATERIALS

The generation of 3-D tissue models based on hyaluronan hydrogel-coated microcarriers within a rotating wall vessel bioreactor

(2010) Aleksander Skardal et al.   BIOMATERIALS

Incorporation of multicellular spheroids into 3-D polymeric scaffolds provides an improved tumor model for screening anticancer drugs

(2010) Won Jin Ho et al.   CANCER SCIENCE

Photocrosslinkable Hyaluronan-Gelatin Hydrogels for Two-Step Bioprinting

(2010) Aleksander Skardal et al.   TISSUE ENGINEERING PART A

Matrix Crosslinking Forces Tumor Progression by Enhancing Integrin Signaling

(2009) Kandice R. Levental et al.   CELL

Engineered extracellular matrices with cleavable crosslinkers for cell expansion and easy cell recovery

(2008) Jianxing Zhang et al.   BIOMATERIALS

Chemically-Modified HA for Therapy and Regenerative Medicine

(2008) Glenn Prestwich et al.   CURRENT PHARMACEUTICAL BIOTECHNOLOGY

Evaluating Drug Efficacy and Toxicology in Three Dimensions: Using Synthetic Extracellular Matrices in Drug Discovery

(2007) Glenn D. Prestwich   ACCOUNTS OF CHEMICAL RESEARCH