Transcriptional bursts explain autosomal random monoallelic expression and affect allelic imbalance

Single-cell RNA counting at allele and isoform resolution using Smart-seq3

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Allele-specific RNA imaging shows that allelic imbalances can arise in tissues through transcriptional bursting

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Burst-Like Transcription of Mutant and Wildtype MYH7-Alleles as Possible Origin of Cell-to-Cell Contractile Imbalance in Hypertrophic Cardiomyopathy

(2018) Judith Montag et al.   Frontiers in Physiology

Genomic encoding of transcriptional burst kinetics

(2018) Anton J. M. Larsson et al.   NATURE

What shapes eukaryotic transcriptional bursting?

(2017) Damien Nicolas et al.   Molecular BioSystems

Comparative Analysis of Single-Cell RNA Sequencing Methods

(2017) Christoph Ziegenhain et al.   MOLECULAR CELL

The Human Cell Atlas

(2017) Aviv Regev et al.   eLife

A Comprehensive Mouse Transcriptomic BodyMap across 17 Tissues by RNA-seq

(2017) Bin Li et al.   Scientific Reports

What’s Luck Got to Do with It: Single Cells, Multiple Fates, and Biological Nondeterminism

(2016) Orsolya Symmons et al.   MOLECULAR CELL

Analysis of allelic expression patterns in clonal somatic cells by single-cell RNA–seq

(2016) Björn Reinius et al.   NATURE GENETICS

Single-Cell Transcriptomics Reveals that Differentiation and Spatial Signatures Shape Epidermal and Hair Follicle Heterogeneity

(2016) Simon Joost et al.   Cell Systems

Random monoallelic expression of autosomal genes: stochastic transcription and allele-level regulation

(2015) Björn Reinius et al.   NATURE REVIEWS GENETICS

Random Monoallelic Gene Expression Increases upon Embryonic Stem Cell Differentiation

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Developmental Dynamics and Disease Potential of Random Monoallelic Gene Expression

(2014) Anne-Valerie Gendrel et al.   DEVELOPMENTAL CELL

Single-Cell RNA-Seq Reveals Dynamic, Random Monoallelic Gene Expression in Mammalian Cells

(2014) Q. Deng et al.   SCIENCE

Smart-seq2 for sensitive full-length transcriptome profiling in single cells

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Inferring the kinetics of stochastic gene expression from single-cell RNA-sequencing data

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STAR: ultrafast universal RNA-seq aligner

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Mammalian Genes Are Transcribed with Widely Different Bursting Kinetics

(2011) D. M. Suter et al.   SCIENCE