Burst-Like Transcription of Mutant and Wildtype MYH7-Alleles as Possible Origin of Cell-to-Cell Contractile Imbalance in Hypertrophic Cardiomyopathy

Intrinsic MYH7 expression regulation contributes to tissue level allelic imbalance in hypertrophic cardiomyopathy

(2017) Judith Montag et al.   JOURNAL OF MUSCLE RESEARCH AND CELL MOTILITY

The myosin mesa and the basis of hypercontractility caused by hypertrophic cardiomyopathy mutations

(2017) Suman Nag et al.   NATURE STRUCTURAL & MOLECULAR BIOLOGY

The myosin mesa and the basis of hypercontractility caused by hypertrophic cardiomyopathy mutations

(2017) Suman Nag et al.   NATURE STRUCTURAL & MOLECULAR BIOLOGY

Biophysical properties of human β-cardiac myosin with converter mutations that cause hypertrophic cardiomyopathy

(2017) Masataka Kawana et al.   Science Advances

A Tension-Based Model Distinguishes Hypertrophic versus Dilated Cardiomyopathy

(2016) Jennifer Davis et al.   CELL

Hypertrophic Cardiomyopathy

(2016) Theresia Kraft et al.   CIRCULATION RESEARCH

Genetic advances in sarcomeric cardiomyopathies: state of the art

(2015) C. Y. Ho et al.   CARDIOVASCULAR RESEARCH

Bursty Gene Expression in the Intact Mammalian Liver

(2015) Keren Bahar Halpern et al.   MOLECULAR CELL

Diltiazem Treatment for Pre-Clinical Hypertrophic Cardiomyopathy Sarcomere Mutation Carriers

(2015) Carolyn Y. Ho et al.   JACC-Heart Failure

Familial hypertrophic cardiomyopathy: functional variance among individual cardiomyocytes as a trigger of FHC-phenotype development

(2014) Bernhard Brenner et al.   Frontiers in Physiology

Mutations in MYH7 reduce the force generating capacity of sarcomeres in human familial hypertrophic cardiomyopathy

(2013) E. Rosalie Witjas-Paalberends et al.   CARDIOVASCULAR RESEARCH

The Hypertrophic Cardiomyopathy Myosin Mutation R453C Alters ATP Binding and Hydrolysis of Human Cardiac β-Myosin

(2013) Marieke Bloemink et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Familial hypertrophic cardiomyopathy: Functional effects of myosin mutation R723G in cardiomyocytes

(2013) Theresia Kraft et al.   JOURNAL OF MOLECULAR AND CELLULAR CARDIOLOGY

Molecular consequences of the R453C hypertrophic cardiomyopathy mutation on human  -cardiac myosin motor function

(2013) R. F. Sommese et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Hypertrophic cardiomyopathy

(2012) Barry J Maron et al.   LANCET

Unequal allelic expression of wild-type and mutated β-myosin in familial hypertrophic cardiomyopathy

(2011) Snigdha Tripathi et al.   BASIC RESEARCH IN CARDIOLOGY

Acoustic microstreaming increases the efficiency of reverse transcription reactions comprising single-cell quantities of RNA

(2011) Wah Boon* et al.   BIOTECHNIQUES

Disease Pathways and Novel Therapeutic Targets in Hypertrophic Cardiomyopathy

(2011) Houman Ashrafian et al.   CIRCULATION RESEARCH

Contractile Dysfunction Irrespective of the Mutant Protein in Human Hypertrophic Cardiomyopathy With Normal Systolic Function

(2011) Sabine J. van Dijk et al.   Circulation-Heart Failure

Cardiac fibrosis in mice with hypertrophic cardiomyopathy is mediated by non-myocyte proliferation and requires Tgf-β

(2010) Polakit Teekakirikul et al.   JOURNAL OF CLINICAL INVESTIGATION

Normal passive viscoelasticity but abnormal myofibrillar force generation in human hypertrophic cardiomyopathy

(2010) Anita C. Hoskins et al.   JOURNAL OF MOLECULAR AND CELLULAR CARDIOLOGY

Single-Molecule Approaches to Stochastic Gene Expression

(2009) Arjun Raj et al.   Annual Review of Biophysics

Nature, Nurture, or Chance: Stochastic Gene Expression and Its Consequences

(2008) Arjun Raj et al.   CELL