A Bacterial Toxin Perturbs Intracellular Amino Acid Balance To Induce Persistence

hipBA toxin-antitoxin systems mediate persistence in Caulobacter crescentus

(2020) Charlie Y. Huang et al.   Scientific Reports

Asymmetric division yields progeny cells with distinct modes of regulating cell cycle-dependent chromosome methylation

(2019) Xiaofeng Zhou et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Serine-Threonine Kinases Encoded by Split hipA Homologs Inhibit Tryptophanyl-tRNA Synthetase

(2019) Stine Vang Nielsen et al.   mBio

Bacterial Persisters and Infection: Past, Present, and Progressing

(2019) Bridget Gollan et al.   Annual Review of Microbiology

Toxins, Targets, and Triggers: An Overview of Toxin-Antitoxin Biology

(2018) Alexander Harms et al.   MOLECULAR CELL

Rsd balances (p)ppGpp level by stimulating the hydrolase activity of SpoT during carbon source downshift inEscherichia coli

(2018) Jae-Woo Lee et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Reassessing the Role of Type II Toxin-Antitoxin Systems in Formation of Escherichia coli Type II Persister Cells

(2018) Frédéric Goormaghtigh et al.   mBio

Regulation of (p)ppGpp hydrolysis by a conserved archetypal regulatory domain

(2018) Séverin Ronneau et al.   NUCLEIC ACIDS RESEARCH

Persistent bacterial infections and persister cells

(2017) Robert A. Fisher et al.   NATURE REVIEWS MICROBIOLOGY

Kinetics of drug–ribosome interactions defines the cidality of macrolide antibiotics

(2017) Maxim S. Svetlov et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

A Localized Complex of Two Protein Oligomers Controls the Orientation of Cell Polarity

(2017) Adam M. Perez et al.   mBio

Prophages and Growth Dynamics Confound Experimental Results with Antibiotic-Tolerant Persister Cells

(2017) Alexander Harms et al.   mBio

Toxin-antitoxin systems in bacterial growth arrest and persistence

(2016) Rebecca Page et al.   Nature Chemical Biology

Mechanisms of bacterial persistence during stress and antibiotic exposure

(2016) Alexander Harms et al.   SCIENCE

Phosphotransferase-dependent accumulation of (p)ppGpp in response to glutamine deprivation in Caulobacter crescentus

(2016) Séverin Ronneau et al.   Nature Communications

MicrobeJ, a tool for high throughput bacterial cell detection and quantitative analysis

(2016) Adrien Ducret et al.   Nature Microbiology

Recent functional insights into the role of (p)ppGpp in bacterial physiology

(2015) Vasili Hauryliuk et al.   NATURE REVIEWS MICROBIOLOGY

Molecular Mechanisms Underlying Bacterial Persisters

(2014) Etienne Maisonneuve et al.   CELL

Effects of (p)ppGpp on the Progression of the Cell Cycle of Caulobacter crescentus

(2014) D. Gonzalez et al.   JOURNAL OF BACTERIOLOGY

HipA-Triggered Growth Arrest and  -Lactam Tolerance in Escherichia coli Are Mediated by RelA-Dependent ppGpp Synthesis

(2013) G. Bokinsky et al.   JOURNAL OF BACTERIOLOGY

Nitrogen Assimilation in Escherichia coli: Putting Molecular Data into a Systems Perspective

(2013) W. C. van Heeswijk et al.   MICROBIOLOGY AND MOLECULAR BIOLOGY REVIEWS

Molecular Mechanism of Bacterial Persistence by HipA

(2013) Elsa Germain et al.   MOLECULAR CELL

Regulation of toxin–antitoxin systems by proteolysis

(2013) Iwona Brzozowska et al.   PLASMID

Bacterial lifestyle shapes stringent response activation

(2013) Cara C. Boutte et al.   TRENDS IN MICROBIOLOGY

HipA-mediated antibiotic persistence via phosphorylation of the glutamyl-tRNA-synthetase

(2013) Ilana Kaspy et al.   Nature Communications

Direct binding targets of the stringent response alarmone (p)ppGpp

(2012) Usheer Kanjee et al.   MOLECULAR MICROBIOLOGY

Correction: Regulation of the Escherichia coli HipBA Toxin-Antitoxin System by Proteolysis

(2012) Sonja Hansen et al.   PLoS One

Toxin-Antitoxin Systems in Bacteria and Archaea

(2011) Yoshihiro Yamaguchi et al.   Annual Review of Genetics

ppGpp and Polyphosphate Modulate Cell Cycle Progression in Caulobacter crescentus

(2011) C. C. Boutte et al.   JOURNAL OF BACTERIOLOGY

The complex logic of stringent response regulation in Caulobacter crescentus: starvation signalling in an oligotrophic environment

(2011) Cara C. Boutte et al.   MOLECULAR MICROBIOLOGY

The essential genome of a bacterium

(2011) B. Christen et al.   Molecular Systems Biology

Diversity of bacterial type II toxin–antitoxin systems: a comprehensive search and functional analysis of novel families

(2011) Raphaël Leplae et al.   NUCLEIC ACIDS RESEARCH

Persister Cells

(2010) Kim Lewis   Annual Review of Microbiology

Mutagenesis and Functional Characterization of the Four Domains of GlnD, a Bifunctional Nitrogen Sensor Protein

(2010) Y. Zhang et al.   JOURNAL OF BACTERIOLOGY

Absolute metabolite concentrations and implied enzyme active site occupancy in Escherichia coli

(2009) Bryson D Bennett et al.   Nature Chemical Biology

Evolution of bacterial trp operons and their regulation

(2008) Enrique Merino et al.   CURRENT OPINION IN MICROBIOLOGY

SpoT Regulates DnaA Stability and Initiation of DNA Replication in Carbon-Starved Caulobacter crescentus

(2008) J. A. Lesley et al.   JOURNAL OF BACTERIOLOGY