Serine-Threonine Kinases Encoded by Split hipA Homologs Inhibit Tryptophanyl-tRNA Synthetase

An NAD+ Phosphorylase Toxin Triggers Mycobacterium tuberculosis Cell Death

(2019) Diana Mendes Freire et al.   MOLECULAR CELL

Serine/Threonine Protein Kinases from Bacteria, Archaea and Eukarya Share a Common Evolutionary Origin Deeply Rooted in the Tree of Life

(2018) Ivan Andreas Stancik et al.   JOURNAL OF MOLECULAR BIOLOGY

Activation of the Stringent Response by Loading of RelA-tRNA Complexes at the Ribosomal A-Site

(2018) Kristoffer Skovbo Winther et al.   MOLECULAR CELL

Toxins, Targets, and Triggers: An Overview of Toxin-Antitoxin Biology

(2018) Alexander Harms et al.   MOLECULAR CELL

The kinases HipA and HipA7 phosphorylate different substrate pools in Escherichia coli to promote multidrug tolerance

(2018) Maja Semanjski et al.   Science Signaling

The RES domain toxins of RES-Xre toxin-antitoxin modules induce cell stasis by degrading NAD+

(2018) Ragnhild Bager Skjerning et al.   MOLECULAR MICROBIOLOGY

AtaT blocks translation initiation by N-acetylation of the initiator tRNAfMet

(2017) Dukas Jurėnas et al.   Nature Chemical Biology

Rapid Curtailing of the Stringent Response by Toxin-Antitoxin Module-Encoded mRNases

(2016) Chengzhe Tian et al.   JOURNAL OF BACTERIOLOGY

A Salmonella Toxin Promotes Persister Formation through Acetylation of tRNA

(2016) Angela M. Cheverton et al.   MOLECULAR CELL

Bacterial persistence is an active σSstress response to metabolic flux limitation

(2016) Jakub Leszek Radzikowski et al.   Molecular Systems Biology

Toxin-antitoxin systems in bacterial growth arrest and persistence

(2016) Rebecca Page et al.   Nature Chemical Biology

Mechanisms of bacterial persistence during stress and antibiotic exposure

(2016) Alexander Harms et al.   SCIENCE

HipBA–promoter structures reveal the basis of heritable multidrug tolerance

(2015) Maria A. Schumacher et al.   NATURE

2016 update of the PRIDE database and its related tools

(2015) Juan Antonio Vizcaíno et al.   NUCLEIC ACIDS RESEARCH

Stochastic induction of persister cells by HipA through (p)ppGpp-mediated activation of mRNA endonucleases

(2015) Elsa Germain et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Selective Target Inactivation Rather than Global Metabolic Dormancy Causes Antibiotic Tolerance in Uropathogens

(2014) Lee W. Goneau et al.   ANTIMICROBIAL AGENTS AND CHEMOTHERAPY

HipA-Triggered Growth Arrest and  -Lactam Tolerance in Escherichia coli Are Mediated by RelA-Dependent ppGpp Synthesis

(2013) G. Bokinsky et al.   JOURNAL OF BACTERIOLOGY

Molecular Mechanism of Bacterial Persistence by HipA

(2013) Elsa Germain et al.   MOLECULAR CELL

HipA-mediated antibiotic persistence via phosphorylation of the glutamyl-tRNA-synthetase

(2013) Ilana Kaspy et al.   Nature Communications

Role of Unusual P Loop Ejection and Autophosphorylation in HipA-Mediated Persistence and Multidrug Tolerance

(2012) Maria A. Schumacher et al.   Cell Reports

Evolution of Stress Response in the Face of Unreliable Environmental Signals

(2012) Markus Arnoldini et al.   PLoS Computational Biology

Andromeda: A Peptide Search Engine Integrated into the MaxQuant Environment

(2011) Jürgen Cox et al.   JOURNAL OF PROTEOME RESEARCH

SecB-like chaperone controls a toxin-antitoxin stress-responsive system in Mycobacterium tuberculosis

(2011) P. Bordes et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Enteric virulence associated protein VapC inhibits translation by cleavage of initiator tRNA

(2011) K. S. Winther et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

New toxins homologous to ParE belonging to three-component toxin-antitoxin systems in Escherichia coli O157:H7

(2010) Régis Hallez et al.   MOLECULAR MICROBIOLOGY

Ciprofloxacin Causes Persister Formation by Inducing the TisB toxin in Escherichia coli

(2010) Tobias Dörr et al.   PLOS BIOLOGY

Molecular Mechanisms of HipA-Mediated Multidrug Tolerance and Its Neutralization by HipB

(2009) M. A. Schumacher et al.   SCIENCE

Bistability, Epigenetics, and Bet-Hedging in Bacteria

(2008) Jan-Willem Veening et al.   Annual Review of Microbiology

HicA of Escherichia coli Defines a Novel Family of Translation-Independent mRNA Interferases in Bacteria and Archaea

(2008) M. G. Jorgensen et al.   JOURNAL OF BACTERIOLOGY

MaxQuant enables high peptide identification rates, individualized p.p.b.-range mass accuracies and proteome-wide protein quantification

(2008) Jürgen Cox et al.   NATURE BIOTECHNOLOGY