Anti-Thrombotic Effects Mediated by Dihydromyricetin Involve Both Platelet Inhibition and Endothelial Protection

Myricetin, the Main Flavonoid in Syzygium cumini Leaf, Is a Novel Inhibitor of Platelet Thiol Isomerases PDI and ERp5

(2020) Renato Simões Gaspar et al.   Frontiers in Pharmacology

Dihydromyricetin increases endothelial nitric oxide production and inhibits atherosclerosis through microRNA‐21 in apolipoprotein E‐deficient mice

(2020) Dafeng Yang et al.   JOURNAL OF CELLULAR AND MOLECULAR MEDICINE

Platelet MAPKs—a 20+ year history: What do we really know?

(2020) Pravin Patel et al.   JOURNAL OF THROMBOSIS AND HAEMOSTASIS

Role of Cell Surface Lipids and Thiol-Disulphide Exchange Pathways in Regulating the Encryption and Decryption of Tissue Factor

(2019) Shabbir Ansari et al.   THROMBOSIS AND HAEMOSTASIS

Dihydromyricetin protects HUVECs of oxidative damage induced by sodium nitroprusside through activating PI3K/Akt/FoxO3a signalling pathway

(2019) Xiaoying Zhang et al.   JOURNAL OF CELLULAR AND MOLECULAR MEDICINE

­­­­Calcium-induced dissociation of CIB1 from ASK1 regulates agonist-induced activation of the p38 MAPK pathway in platelets

(2019) Pravin Patel et al.   BIOCHEMICAL JOURNAL

Multitarget and promising role of dihydromyricetin in the treatment of metabolic diseases

(2019) Haihui Tong et al.   EUROPEAN JOURNAL OF PHARMACOLOGY

The search for new antithrombotic mechanisms and therapies that may spare hemostasis

(2018) Edward F. Plow et al.   BLOOD

Experimental design and analysis and their reporting II: updated and simplified guidance for authors and peer reviewers

(2018) Michael J Curtis et al.   BRITISH JOURNAL OF PHARMACOLOGY

Procoagulant activity during viral infections

(2018) Inge Scharrer   Frontiers in Bioscience-Landmark

Protective effect of dihydromyricetin on LPS-induced acute lung injury

(2018) Bo Wang et al.   JOURNAL OF LEUKOCYTE BIOLOGY

Dihydromyricetin improves vascular hyporesponsiveness in experimental sepsis via attenuating the over-excited MaxiK and KATP channels

(2018) Jin Peng et al.   PHARMACEUTICAL BIOLOGY

Testing and monitoring direct oral anticoagulants

(2018) Jean M. Connors   BLOOD

Study of Methanol Extracts from Different Parts of Peganum harmala L. Using 1H-NMR Plant Metabolomics

(2018) Yinping Li et al.   Journal of Analytical Methods in Chemistry

Novel Noncatalytic Substrate-Selective p38α-Specific MAPK Inhibitors with Endothelial-Stabilizing and Anti-Inflammatory Activity

(2017) Nirav G. Shah et al.   JOURNAL OF IMMUNOLOGY

Protein disulfide isomerase secretion following vascular injury initiates a regulatory pathway for thrombus formation

(2017) Sheryl R. Bowley et al.   Nature Communications

Disulfide Bonds as Regulators of Integrin Function in Thrombosis and Hemostasis

(2016) Ronit Mor-Cohen   ANTIOXIDANTS & REDOX SIGNALING

Vascular thiol isomerases

(2016) Robert Flaumenhaft et al.   BLOOD

von Willebrand factor multimerization and the polarity of secretory pathways in endothelial cells

(2016) M. Lopes da Silva et al.   BLOOD

Getting to the Outer Leaflet: Physiology of Phosphatidylserine Exposure at the Plasma Membrane

(2016) Edouard M. Bevers et al.   PHYSIOLOGICAL REVIEWS

Endothelial cell control of thrombosis

(2015) Jonathan W. Yau et al.   BMC Cardiovascular Disorders

Bach1 Represses Wnt/β-Catenin Signaling and AngiogenesisNovelty and Significance

(2015) Li Jiang et al.   CIRCULATION RESEARCH

Inhibition of adenosine diphosphate-induced platelet aggregation by alpha-lipoic acid and dihydroquercetin in vitro

(2014) MarkB Plotnikov et al.   INDIAN JOURNAL OF PHARMACOLOGY

Synergies of phosphatidylserine and protein disulfide isomerase in tissue factor activation

(2014) Wolfram Ruf et al.   THROMBOSIS AND HAEMOSTASIS

Angiotensin 1-7 and Mas decrease thrombosis in Bdkrb2-/- mice by increasing NO and prostacyclin to reduce platelet spreading and glycoprotein VI activation

(2013) C. Fang et al.   BLOOD

Platelet protein disulfide isomerase is required for thrombus formation but not for hemostasis in mice

(2013) K. Kim et al.   BLOOD

Advances in platelet granule biology

(2013) Secil Koseoglu et al.   CURRENT OPINION IN HEMATOLOGY

Encryption and decryption of tissue factor

(2013) V. M. Chen et al.   JOURNAL OF THROMBOSIS AND HAEMOSTASIS

Protein disulfide isomerase capture during thrombus formation in vivo depends on the presence of  3 integrins

(2012) J. Cho et al.   BLOOD

Protein disulfide isomerase inhibitors constitute a new class of antithrombotic agents

(2012) Reema Jasuja et al.   JOURNAL OF CLINICAL INVESTIGATION

Regulation of tissue factor coagulant activity on cell surfaces

(2012) L. V. M. RAO et al.   JOURNAL OF THROMBOSIS AND HAEMOSTASIS

Arterial thrombosis—insidious, unpredictable and deadly

(2011) Shaun P Jackson   NATURE MEDICINE

Signaling During Platelet Adhesion and Activation

(2010) Zhenyu Li et al.   ARTERIOSCLEROSIS THROMBOSIS AND VASCULAR BIOLOGY

Laser-induced endothelial cell activation supports fibrin formation

(2010) B. T. Atkinson et al.   BLOOD

Extracellular protein disulfide isomerase regulates coagulation on endothelial cells through modulation of phosphatidylserine exposure

(2010) N. I. Popescu et al.   BLOOD

Endothelium-derived but not platelet-derived protein disulfide isomerase is required for thrombus formation in vivo

(2010) R. Jasuja et al.   BLOOD

Cell biology of Ca2+-triggered exocytosis

(2010) Zhiping P Pang et al.   CURRENT OPINION IN CELL BIOLOGY

Activation of endothelial intrinsic NF- B pathway impairs protein C anticoagulation mechanism and promotes coagulation in endotoxemic mice

(2009) D. Song et al.   BLOOD

Calcium signaling in platelets

(2009) D. VARGA-SZABO et al.   JOURNAL OF THROMBOSIS AND HAEMOSTASIS

Future innovations in anti-platelet therapies

(2008) N E Barrett et al.   BRITISH JOURNAL OF PHARMACOLOGY

Mechanisms of Thrombus Formation

(2008) Bruce Furie et al.   NEW ENGLAND JOURNAL OF MEDICINE