A room-temperature protocol to access isoquinolines through Ag(i) catalysed annulation of o-(1-alkynyl)arylaldehydes and ketones with NH4OAc: elaboration to berberine and palmatine

Short and Efficient Syntheses of Protoberberine Alkaloids using Palladium-Catalyzed Enolate Arylation

(2014) Alice E. Gatland et al.   ANGEWANDTE CHEMIE-INTERNATIONAL EDITION

Silver(I)-Catalyzed Route to Pyrroles: Synthesis of Halogenated Pseudilins as Allosteric Inhibitors for Myosin ATPase and X-ray Crystal Structures of the Protein-Inhibitor Complexes

(2014) René Martin et al.   EUROPEAN JOURNAL OF ORGANIC CHEMISTRY

Isoquinoline skeleton synthesis via chelation-assisted C−H activation

(2014) Ruoyu He et al.   TETRAHEDRON LETTERS

Synthesis of substituted isoquinolines via iminoalkyne cyclization using Ag(i) exchanged K10-montmorillonite clay as a reusable catalyst

(2014) Mariappan Jeganathan et al.   RSC Advances

Efficient synthesis of isoquinolines and pyridines via copper(i)-catalyzed multi-component reaction

(2014) Kommuri Shekarrao et al.   RSC Advances

Facile Assembly of 1-[(Trifluoromethyl)thio]isoquinolines through Reaction of 2-Alkynylbenzaldoxime with Silver (Trifluoromethyl)thiolate

(2013) Qing Xiao et al.   EUROPEAN JOURNAL OF ORGANIC CHEMISTRY

Total Synthesis of the Marine Alkaloid Mansouramycin D

(2013) K. S. Prakash et al.   ORGANIC LETTERS

Activating Group Recycling in Action: A Rhodium-Catalyzed Carbothiolation Route to Substituted Isoquinolines

(2013) Milan Arambasic et al.   ORGANIC LETTERS

Modular Isoquinoline Synthesis Using Catalytic Enolate Arylation and in Situ Functionalization

(2013) Ben S. Pilgrim et al.   ORGANIC LETTERS

One-pot synthesis of isoquinoline and related compounds via Cu-mediated tandem cross-coupling and cyclization

(2013) Shubhendu Dhara et al.   TETRAHEDRON LETTERS

Gold-Catalyzed Synthesis of Dibenzopentalenes - Evidence for Gold Vinylidenes

(2012) A. Stephen K. Hashmi et al.   ADVANCED SYNTHESIS & CATALYSIS

Facile Synthesis of 3-Substituted Isoquinolines Derivatives via Microwave-assisted Tandem Three-component Coupling Cyclization

(2012) Long Lin et al.   CHINESE JOURNAL OF CHEMISTRY

AgI-Catalyzed Cascade Strategy: Regioselective Access to Diversely Substituted Fused Benzimidazo[2,1-a]isoquinolines, Naphthyridines, Thienopyridines, and Quinoxalines in Water

(2012) Vineeta Rustagi et al.   EUROPEAN JOURNAL OF ORGANIC CHEMISTRY

Synthesis of Isoquinolines and Heterocycle-Fused Pyridines via Three-Component Cascade Reaction of Aryl Ketones, Hydroxylamine, and Alkynes

(2012) Liyao Zheng et al.   JOURNAL OF ORGANIC CHEMISTRY

C–H Bond Functionalization via Hydride Transfer: Formation of α-Arylated Piperidines and 1,2,3,4-Tetrahydroisoquinolines via Stereoselective Intramolecular Amination of Benzylic C–H Bonds

(2012) Paul A. Vadola et al.   JOURNAL OF ORGANIC CHEMISTRY

Microwave-Assisted One-Pot Synthesis of Isoquinolines, Furopyridines, and Thienopyridines by Palladium-Catalyzed Sequential Coupling–Imination–Annulation of 2-Bromoarylaldehydes with Terminal Acetylenes and Ammonium Acetate

(2012) Dingqiao Yang et al.   JOURNAL OF ORGANIC CHEMISTRY

Synthesis and Cytotoxicity Evaluation of 13-n-Alkyl Berberine and Palmatine Analogues as Anticancer Agents

(2012) Lei Zhang et al.   MOLECULES

An Unexpected Silver Triflate Catalyzed Reaction of 2-Alkynylbenzaldehyde with 2-Isocyanoacetate

(2012) Danqing Zheng et al.   ORGANIC LETTERS

Ruthenium-Catalyzed Highly Regioselective Cyclization of Ketoximes with Alkynes by C–H Bond Activation: A Practical Route to Synthesize Substituted Isoquinolines

(2012) Ravi Kiran Chinnagolla et al.   ORGANIC LETTERS

Synthesis of substituted isoquinolines utilizing palladium-catalyzed  -arylation of ketones

(2012) T. J. Donohoe et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

One-pot two-step synthesis of 1-position arylated 1,3-disubstituted isoquinoline N-oxides

(2012) Qiuping Ding et al.   TETRAHEDRON

Regio- and Stereoselective Carbobismuthination of Alkynes

(2011) Yoshihiro Nishimoto et al.   ANGEWANDTE CHEMIE-INTERNATIONAL EDITION

Synthesis of 9-substituted derivatives of berberine as anti-HIV agents

(2011) Hardik S. Bodiwala et al.   EUROPEAN JOURNAL OF MEDICINAL CHEMISTRY

Highly efficient Ag(i)-catalyzed regioselective tandem synthesis of diversely substituted quinoxalines and benzimidazoles in water

(2011) Vineeta Rustagi et al.   GREEN CHEMISTRY

Selectiveortho-Bromination of Substituted Benzaldoximes Using Pd-Catalyzed C–H Activation: Application to the Synthesis of Substituted 2-Bromobenzaldehydes

(2011) Emmanuelle Dubost et al.   JOURNAL OF ORGANIC CHEMISTRY

Silver-catalysed intramolecular cyclisation of 2-alkynylacetophenones and 3-acetyl-2-alkynylpyridines in the presence of ammonia

(2011) Monica Dell'Acqua et al.   ORGANIC & BIOMOLECULAR CHEMISTRY

Synthesis of functionalized ellipticinium and ellipticine derivatives via electrophilic cyclization

(2011) T. Krishna Chaitanya et al.   ORGANIC & BIOMOLECULAR CHEMISTRY

NHC-Catalyzed Oxidative Cyclization Reactions of 2-Alkynylbenzaldehydes under Aerobic Conditions: Synthesis of O-Heterocycles

(2011) Jong Hyub Park et al.   ORGANIC LETTERS

Synthesis of 1-Aminoisoquinolines via Rh(III)-Catalyzed Oxidative Coupling

(2011) Xiaohong Wei et al.   ORGANIC LETTERS

Osmium-Catalyzed 7-endo Heterocyclization of Aromatic Alkynols into Benzoxepines

(2010) Alejandro Varela-Fernández et al.   ANGEWANDTE CHEMIE-INTERNATIONAL EDITION

Gold(I)- and Yb(OTf)3-Cocatalyzed Rearrangements of Epoxy Alkynes: Transfer of a Carbonyl Group in a Five-Membered Carbocycle

(2010) Lun-Zhi Dai et al.   CHEMISTRY-A EUROPEAN JOURNAL

Indole as Neutral Leaving Group in Silver Nitrate Induced Cyclization Reactions ofN-{2-[Alkynyl(hetero)aryl]methylene}indolin-1-amines for the Synthesis of Annulated Pyridine Derivatives

(2010) Nugzar Ghavtadze et al.   EUROPEAN JOURNAL OF ORGANIC CHEMISTRY

Rhodium(III)-Catalyzed Synthesis of Isoquinolines from Aryl KetoneO-Acyloxime Derivatives and Internal Alkynes

(2010) Pei Chui Too et al.   ORGANIC LETTERS

1-(Isoquinolin-1-yl)urea Library Generation via Three-Component Reaction of 2-Alkynylbenzaldoxime, Carbodiimide, with Electrophile

(2010) Shengqing Ye et al.   ACS Combinatorial Science

Multicatalytic Tandem Reactions of 2-Alkynylbenzaldoximes with Isocyanides

(2009) Zhiyuan Chen et al.   ADVANCED SYNTHESIS & CATALYSIS

Total Synthesis of Pentabromo- and Pentachloropseudilin, and Synthetic Analogues-Allosteric Inhibitors of Myosin ATPase

(2009) René Martin et al.   ANGEWANDTE CHEMIE-INTERNATIONAL EDITION

A systematic review of the anticancer properties of berberine, a natural product from Chinese herbs

(2009) Yiyi Sun et al.   ANTI-CANCER DRUGS

Synthesis and biological evaluation of berberine analogues as novel up-regulators for both low-density-lipoprotein receptor and insulin receptor

(2009) Yan-Xiang Wang et al.   BIOORGANIC & MEDICINAL CHEMISTRY LETTERS

AgOTf-catalyzed tandem reaction of N′-(2-alkynylbenzylidene)hydrazide with alkyne

(2009) Zhiyuan Chen et al.   CHEMICAL COMMUNICATIONS

Microwave-Promoted Synthesis ofN-Heterocycles by Tandem Imination/Annulation of γ- and δ-Ketoalkynes in the Presence of Ammonia

(2009) Maria Alfonsi et al.   EUROPEAN JOURNAL OF ORGANIC CHEMISTRY

Palladium- and Copper-Catalyzed Solution Phase Synthesis of a Diverse Library of Isoquinolines

(2009) Sudipta Roy et al.   JOURNAL OF COMBINATORIAL CHEMISTRY

Isoquinoline Synthesis via Rhodium-Catalyzed Oxidative Cross-Coupling/Cyclization of Aryl Aldimines and Alkynes

(2009) Nicolas Guimond et al.   JOURNAL OF THE AMERICAN CHEMICAL SOCIETY

Orthogonal Synthesis of Isoindole and Isoquinoline Derivatives from Organic Azides

(2009) Benjamin Wei-Qiang Hui et al.   ORGANIC LETTERS

AgOTf and TfOH co-catalyzed isoquinoline synthesis via redox reactions of O-alkyl oximes

(2009) Soojin Hwang et al.   TETRAHEDRON LETTERS

Lewis acid-catalyzed reactions of N′-(2-alkynylbenzylidene)hydrazides with diethyl phosphite

(2009) Xingxin Yu et al.   TETRAHEDRON LETTERS

Gold-catalyzed synthesis of isoquinolines via intramolecular cyclization of 2-alkynyl benzyl azides

(2009) Zhibao Huo et al.   TETRAHEDRON LETTERS

A Dramatic Substituent Effect in Silver(I)-Catalyzed Regioselective Cyclization of ortho-Alkynylaryl Aldehyde Oxime Derivatives

(2008) Hongyin Gao et al.   ADVANCED SYNTHESIS & CATALYSIS

Synthesis and structure–activity relationships of berberine analogues as a novel class of low-density-lipoprotein receptor up-regulators

(2008) Peng Yang et al.   BIOORGANIC & MEDICINAL CHEMISTRY LETTERS

A Tandem Approach to Isoquinolines from 2-Azido-3-arylacrylates and α-Diazocarbonyl Compounds

(2008) Yun-Yun Yang et al.   JOURNAL OF ORGANIC CHEMISTRY

Iodine-Mediated Electrophilic Cyclization of 2-Alkynyl-1-methylene Azide Aromatics Leading to Highly Substituted Isoquinolines and Its Application to the Synthesis of Norchelerythrine

(2008) Dirk Fischer et al.   JOURNAL OF THE AMERICAN CHEMICAL SOCIETY

Orthogonal Synthesis of Indolines and Isoquinolines via Aryne Annulation

(2008) Christopher D. Gilmore et al.   JOURNAL OF THE AMERICAN CHEMICAL SOCIETY

Combination of simvastatin with berberine improves the lipid-lowering efficacy

(2008) Wei-Jia Kong et al.   METABOLISM-CLINICAL AND EXPERIMENTAL

A Versatile Cyclodehydration Reaction for the Synthesis of Isoquinoline and β-Carboline Derivatives

(2008) Mohammad Movassaghi et al.   ORGANIC LETTERS

Assembly of Isoquinolines via CuI-Catalyzed Coupling of β-Keto Esters and 2-Halobenzylamines

(2008) Bao Wang et al.   ORGANIC LETTERS

Copper-free Sonogashira coupling of 2-chloroquinolines with phenyl acetylene and quick annulation to benzo[b][1,6]naphthyridine derivatives in aqueous ammonia

(2008) Atish Chandra et al.   TETRAHEDRON