Modulating inflammation through the neutralization of Interleukin-6 and tumor necrosis factor-α by biofunctionalized nanoparticles

Intra-articular targeting of nanomaterials for the treatment of osteoarthritis

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Biofunctional Nanofibrous Substrate for Local TNF-Capturing as a Strategy to Control Inflammation in Arthritic Joints

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Biodegradable polymers: an update on drug delivery in bone and cartilage diseases

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Nanomedicines for improved targetability to inflamed synovium for treatment of rheumatoid arthritis: Multi-functionalization as an emerging strategy to optimize therapeutic efficacy

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Cytokines in Inflammatory Disease

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Chronic inflammation in the etiology of disease across the life span

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Interleukin-6 Neutralization by Antibodies Immobilized at the Surface of Polymeric Nanoparticles as a Therapeutic Strategy for Arthritic Diseases

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Importance of integrating nanotechnology with pharmacology and physiology for innovative drug delivery and therapy – an illustration with firsthand examples

(2018) Rui Xue Zhang et al.   ACTA PHARMACOLOGICA SINICA

A novel fusion protein attenuates collagen–induced arthritis by targeting interleukin 17A and tumor necrosis factor α

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ABT-122, a Bispecific DVD-Immunoglobulin Targeting TNF- and IL-17A, in RA With Inadequate Response to Methotrexate: A Randomized, Double-Blind Study

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Phase 2 Study of ABT-122, a TNF- and IL-17A-Targeted Dual Variable Domain Immunoglobulin, in Psoriatic Arthritis With Inadequate Methotrexate Response

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Biomimetic nanoparticles for inflammation targeting

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Active agents, biomaterials, and technologies to improve biolubrication and strengthen soft tissues

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Monocytes in rheumatoid arthritis: Circulating precursors of macrophages and osteoclasts and, their heterogeneity and plasticity role in RA pathogenesis

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Dosing down with biologic therapies: a systematic review and clinicians’ perspective

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Effect of particle size on the biodistribution of nano- and microparticles following intra-articular injection in mice

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Chondroprotective effect of high-molecular-weight hyaluronic acid on osteoarthritic chondrocytes in a co-cultivation inflammation model with M1 macrophages

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Differential uptake of nanoparticles by human M1 and M2 polarized macrophages: protein corona as a critical determinant

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Trojan horses and guided missiles: targeted therapies in the war on arthritis

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Polymeric nanoparticles: the future of nanomedicine

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Hyaluronate–Gold Nanoparticle/Tocilizumab Complex for the Treatment of Rheumatoid Arthritis

(2014) Hwiwon Lee et al.   ACS Nano

Amitriptyline reverses hyperalgesia and improves associated mood-like disorders in a model of experimental monoarthritis

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Intra-articular delivery of kartogenin-conjugated chitosan nano/microparticles for cartilage regeneration

(2014) Mi Lan Kang et al.   BIOMATERIALS

Intra-articular administration of gelatin hydrogels incorporating rapamycin–micelles reduces the development of experimental osteoarthritis in a murine model

(2014) Tokio Matsuzaki et al.   BIOMATERIALS

The Role of Inflammatory and Anti-Inflammatory Cytokines in the Pathogenesis of Osteoarthritis

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Drug delivery systems for intra-articular treatment of osteoarthritis

(2013) Mi Lan Kang et al.   Expert Opinion on Drug Delivery

Conditioned medium as a strategy for human stem cells chondrogenic differentiation

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(2013) Christopher H. Evans et al.   Nature Reviews Rheumatology

Etanercept decreases synovial expression of tumour necrosis factor-α and lymphotoxin-α in rheumatoid arthritis

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Anti-Inflammatory Therapy in Chronic Disease: Challenges and Opportunities

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Dual targeting strategies with bispecific antibodies

(2012) Roland Kontermann   mAbs

Safety of biologic therapy in rheumatoid arthritis

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The impact of age on emotional and cognitive behaviours triggered by experimental neuropathy in rats

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