FIREWORKS: a bottom-up approach to integrative coessentiality network analysis

Next-generation characterization of the Cancer Cell Line Encyclopedia

(2019) Mahmoud Ghandi et al.   NATURE

Toward an integrated map of genetic interactions in cancer cells

(2018) Benedikt Rauscher et al.   Molecular Systems Biology

Interrogation of Mammalian Protein Complex Structure, Function, and Membership Using Genome-Scale Fitness Screens

(2018) Joshua Pan et al.   Cell Systems

High‐resolution mapping of cancer cell networks using co‐functional interactions

(2018) Evan A Boyle et al.   Molecular Systems Biology

CORUM: the comprehensive resource of mammalian protein complexes—2019

(2018) Madalina Giurgiu et al.   NUCLEIC ACIDS RESEARCH

COXPRESdb v7: a gene coexpression database for 11 animal species supported by 23 coexpression platforms for technical evaluation and evolutionary inference

(2018) Takeshi Obayashi et al.   NUCLEIC ACIDS RESEARCH

STRING v11: protein–protein association networks with increased coverage, supporting functional discovery in genome-wide experimental datasets

(2018) Damian Szklarczyk et al.   NUCLEIC ACIDS RESEARCH

Improved estimation of cancer dependencies from large-scale RNAi screens using model-based normalization and data integration

(2018) James M. McFarland et al.   Nature Communications

eIF4A inhibition: ready for primetime?

(2018) Tyler A. Cunningham et al.   Oncotarget

Computational correction of copy number effect improves specificity of CRISPR–Cas9 essentiality screens in cancer cells

(2017) Robin M Meyers et al.   NATURE GENETICS

Emerging and evolving concepts in gene essentiality

(2017) Giulia Rancati et al.   NATURE REVIEWS GENETICS

DGIdb 3.0: a redesign and expansion of the drug–gene interaction database

(2017) Kelsy C Cotto et al.   NUCLEIC ACIDS RESEARCH

Optimized sgRNA design to maximize activity and minimize off-target effects of CRISPR-Cas9

(2016) John G Doench et al.   NATURE BIOTECHNOLOGY

HIF prolyl hydroxylase inhibitors for the treatment of renal anaemia and beyond

(2015) Patrick H. Maxwell et al.   Nature Reviews Nephrology

The Molecular Signatures Database Hallmark Gene Set Collection

(2015) Arthur Liberzon et al.   Cell Systems

The MAPK pathway across different malignancies: A new perspective

(2014) Mauricio Burotto et al.   CANCER

The Reprogramming of Tumor Stroma by HSF1 Is a Potent Enabler of Malignancy

(2014) Ruth Scherz-Shouval et al.   CELL

CDK7 Inhibition Suppresses Super-Enhancer-Linked Oncogenic Transcription in MYCN-Driven Cancer

(2014) Edmond Chipumuro et al.   CELL

The Master Regulator of the Cellular Stress Response (HSF1) Is Critical for Orthopoxvirus Infection

(2014) Claire Marie Filone et al.   PLoS Pathogens

Tight Coordination of Protein Translation and HSF1 Activation Supports the Anabolic Malignant State

(2013) S. Santagata et al.   SCIENCE

HSF1 Drives a Transcriptional Program Distinct from Heat Shock to Support Highly Malignant Human Cancers

(2012) Marc L. Mendillo et al.   CELL

Differential network biology

(2012) Trey Ideker et al.   Molecular Systems Biology

The Duplicated Genes Database: Identification and Functional Annotation of Co-Localised Duplicated Genes across Genomes

(2012) Marion Ouedraogo et al.   PLoS One

The cBio Cancer Genomics Portal: An Open Platform for Exploring Multidimensional Cancer Genomics Data: Figure 1.

(2012) Ethan Cerami et al.   Cancer Discovery

Rewiring of Genetic Networks in Response to DNA Damage

(2010) S. Bandyopadhyay et al.   SCIENCE

Kinetic Mechanism and Inhibitor Characterization of WNK1 Kinase

(2009) Yukiko I. Yagi et al.   BIOCHEMISTRY

BioMart – biological queries made easy

(2009) Damian Smedley et al.   BMC GENOMICS

The Chemical Genomic Portrait of Yeast: Uncovering a Phenotype for All Genes

(2008) M. E. Hillenmeyer et al.   SCIENCE