Changes in Visual Function and Correlations with Inner Retinal Structure in Acute and Chronic Leber’s Hereditary Optic Neuropathy Patients after Treatment with Idebenone

Real-World Clinical Experience With Idebenone in the Treatment of Leber Hereditary Optic Neuropathy

(2020) Claudia B. Catarino et al.   JOURNAL OF NEURO-OPHTHALMOLOGY

Neuroenhancement and neuroprotection by oral solution citicoline in non-arteritic ischemic optic neuropathy as a model of neurodegeneration: A randomized pilot study

(2019) Vincenzo Parisi et al.   PLoS One

Propagation and Selectivity of Axonal Loss in Leber Hereditary Optic Neuropathy

(2019) Razek Georges Coussa et al.   Scientific Reports

Visual function in chronic Leber’s hereditary optic neuropathy during idebenone treatment initiated 5 to 50 years after onset

(2019) Berthold Pemp et al.   GRAEFES ARCHIVE FOR CLINICAL AND EXPERIMENTAL OPHTHALMOLOGY

The idebenone metabolite QS10 restores electron transfer in complex I and coenzyme Q defects

(2018) Valentina Giorgio et al.   BIOCHIMICA ET BIOPHYSICA ACTA-BIOENERGETICS

Querectin improves myelin repair of optic chiasm in lyolecithin-induced focal demyelination model

(2018) Reza Naeimi et al.   BIOMEDICINE & PHARMACOTHERAPY

The coma in glaucoma: Retinal ganglion cell dysfunction and recovery

(2018) Lewis E. Fry et al.   PROGRESS IN RETINAL AND EYE RESEARCH

Treatment strategies for Leber hereditary optic neuropathy

(2018) Neringa Jurkute et al.   CURRENT OPINION IN NEUROLOGY

International Consensus Statement on the Clinical and Therapeutic Management of Leber Hereditary Optic Neuropathy

(2017) Valerio Carelli et al.   JOURNAL OF NEURO-OPHTHALMOLOGY

Evaluating the therapeutic potential of idebenone and related quinone analogues in Leber hereditary optic neuropathy

(2017) Patrick Yu-Wai-Man et al.   MITOCHONDRION

Natural History of Conversion of Leber's Hereditary Optic Neuropathy

(2017) Tiffany Jean Hwang et al.   OPHTHALMOLOGY

Visual prognosis better in eyes with less severe reduction of visual acuity one year after onset of Leber hereditary optic neuropathy caused by the 11,778 mutation

(2017) Yukihiko Mashima et al.   BMC Ophthalmology

Resveratrol Promotes Remyelination in Cuprizone Model of Multiple Sclerosis: Biochemical and Histological Study

(2016) Heba R. Ghaiad et al.   MOLECULAR NEUROBIOLOGY

The m.13051G>A mitochondrial DNA mutation results in variable neurology and activated mitophagy

(2016) Eszter Dombi et al.   NEUROLOGY

Macular nerve fibre and ganglion cell layer changes in acute Leber's hereditary optic neuropathy

(2015) Nicole Balducci et al.   BRITISH JOURNAL OF OPHTHALMOLOGY

Polymerized nano-curcumin attenuates neurological symptoms in EAE model of multiple sclerosis through down regulation of inflammatory and oxidative processes and enhancing neuroprotection and myelin repair

(2015) Maryam Mohajeri et al.   NEUROPHARMACOLOGY

Exploring the Role of Nerve Growth Factor in Multiple Sclerosis: Implications in Myelin Repair

(2014) C.M.R. Acosta et al.   CNS & Neurological Disorders-Drug Targets

Characterization of macular thickness changes in Leber’s hereditary optic neuropathy by optical coherence tomography

(2014) Yixin Zhang et al.   BMC Ophthalmology

Trial End Points and Natural History in Patients With G11778A Leber Hereditary Optic Neuropathy

(2014) Byron L. Lam et al.   JAMA Ophthalmology

Efficient mitochondrial biogenesis drives incomplete penetrance in Leber’s hereditary optic neuropathy

(2013) Carla Giordano et al.   BRAIN

The effects of idebenone on mitochondrial bioenergetics

(2011) Valentina Giorgio et al.   BIOCHIMICA ET BIOPHYSICA ACTA-BIOENERGETICS

Idebenone Treatment In Leber's Hereditary Optic Neuropathy

(2011) V. Carelli et al.   BRAIN

A randomized placebo-controlled trial of idebenone in Leber’s hereditary optic neuropathy

(2011) Thomas Klopstock et al.   BRAIN

Meta-analysis of the prevalence of Leber hereditary optic neuropathy mtDNA mutations in Europe

(2011) Barbara Mascialino et al.   EUROPEAN JOURNAL OF OPHTHALMOLOGY

NQO1-Dependent Redox Cycling of Idebenone: Effects on Cellular Redox Potential and Energy Levels

(2011) Roman H. Haefeli et al.   PLoS One

Natural History of Leber's Hereditary Optic Neuropathy: Longitudinal Analysis of the Retinal Nerve Fiber Layer by Optical Coherence Tomography

(2010) Piero Barboni et al.   OPHTHALMOLOGY

Vitamins E and D3 Attenuate Demyelination and Potentiate Remyelination Processes of Hippocampal Formation of Rats Following Local Injection of Ethidium Bromide

(2009) Mahdi Goudarzvand et al.   CELLULAR AND MOLECULAR NEUROBIOLOGY

Vision related quality of life in multiple sclerosis: correlation with new measures of low and high contrast letter acuity

(2009) E M Mowry et al.   JOURNAL OF NEUROLOGY NEUROSURGERY AND PSYCHIATRY