NQO1-Dependent Redox Cycling of Idebenone: Effects on Cellular Redox Potential and Energy Levels

NAD(P)H:quinone acceptor oxidoreductase 1 (NQO1), a multifunctional antioxidant enzyme and exceptionally versatile cytoprotector

(2010) Albena T. Dinkova-Kostova et al.   ARCHIVES OF BIOCHEMISTRY AND BIOPHYSICS

Therapeutic use of coenzyme Q10and coenzyme Q10-related compounds and formulations

(2010) Jose M Villalba et al.   EXPERT OPINION ON INVESTIGATIONAL DRUGS

Pharmacological Stimulation of NADH Oxidation Ameliorates Obesity and Related Phenotypes in Mice

(2009) J. H. Hwang et al.   DIABETES

Evidence for NAD(P)H:quinone oxidoreductase 1 (NQO1)-mediated quinone-dependent redox cycling via plasma membrane electron transport: A sensitive cellular assay for NQO1

(2009) An S. Tan et al.   FREE RADICAL BIOLOGY AND MEDICINE

Pharmacokinetic properties and metabolism of idebenone

(2009) Klaus Kutz et al.   JOURNAL OF NEUROLOGY

Differential effects of mitochondrial Complex I inhibitors on production of reactive oxygen species

(2008) Romana Fato et al.   BIOCHIMICA ET BIOPHYSICA ACTA-BIOENERGETICS

Idebenone in Friedreich's ataxia

(2008) Caterina Tonon et al.   EXPERT OPINION ON PHARMACOTHERAPY

Mitochondrial abnormalities in spinal and bulbar muscular atrophy

(2008) Srikanth Ranganathan et al.   HUMAN MOLECULAR GENETICS

Modification of respiratory-chain enzyme activities in brown adipose tissue mitochondria by idebenone (hydroxydecyl-ubiquinone)

(2008) H. Rauchová et al.   JOURNAL OF BIOENERGETICS AND BIOMEMBRANES

Efficacy of idebenone for respiratory failure in a patient with Leigh syndrome: A long-term follow-up study

(2008) Kazuhiro Haginoya et al.   JOURNAL OF THE NEUROLOGICAL SCIENCES

Biochemical study of idebenone effect on mitochondrial metabolism of yeast

(2007) S CHAPELA et al.   CELL BIOLOGY INTERNATIONAL

Antioxidant use in Friedreich ataxia

(2007) Lauren Myers et al.   JOURNAL OF THE NEUROLOGICAL SCIENCES

Natural and synthetic quinones and their reduction by the quinone reductase enzyme NQO1: from synthetic organic chemistry to compounds with anticancer potential

(2007) Marie A. Colucci et al.   ORGANIC & BIOMOLECULAR CHEMISTRY