The mechanism of kinesin inhibition by kinesin-binding protein

A conformational switch in response to Chi converts RecBCD from phage destruction to DNA repair

(2020) Kaiying Cheng et al.   NATURE STRUCTURAL & MOLECULAR BIOLOGY

Structure of Microtubule-Trapped Human Kinesin-5 and Its Mechanism of Inhibition Revealed Using Cryoelectron Microscopy

(2020) Alejandro Peña et al.   STRUCTURE

Goldberg–Shprintzen syndrome is determined by the absence, or reduced expression levels, of KIFBP

(2020) Katherine C. MacKenzie et al.   HUMAN MUTATION

High-resolution structure determination of sub-100 kDa complexes using conventional cryo-EM

(2019) Mark A. Herzik et al.   Nature Communications

Kinesin-binding protein ensures accurate chromosome segregation by buffering KIF18A and KIF15

(2019) Heidi L.H. Malaby et al.   JOURNAL OF CELL BIOLOGY

The tetratricopeptide-repeat motif is a versatile platform that enables diverse modes of molecular recognition

(2019) Albert Perez-Riba et al.   CURRENT OPINION IN STRUCTURAL BIOLOGY

Single particle cryo-EM reconstruction of 52 kDa streptavidin at 3.2 Angstrom resolution

(2019) Xiao Fan et al.   Nature Communications

Motor–cargo adaptors at the organelle–cytoskeleton interface

(2019) Jessica A Cross et al.   CURRENT OPINION IN CELL BIOLOGY

A microtubule RELION-based pipeline for cryo-EM image processing

(2019) Alexander D. Cook et al.   JOURNAL OF STRUCTURAL BIOLOGY

Structural determinants of microtubule minus end preference in CAMSAP CKK domains

(2019) Joseph Atherton et al.   Nature Communications

Multiple Functions of KBP in Neural Development Underlie Brain Anomalies in Goldberg-Shprintzen Syndrome

(2019) Hsin-Yun Chang et al.   Frontiers in Molecular Neuroscience

Accumulation of potential driver genes with genomic alterations predicts survival of high-risk neuroblastoma patients

(2018) Chen Suo et al.   Biology Direct

A Completely Reimplemented MPI Bioinformatics Toolkit with a New HHpred Server at its Core

(2018) Lukas Zimmermann et al.   JOURNAL OF MOLECULAR BIOLOGY

Structure of the 30 kDa HIV-1 RNA Dimerization Signal by a Hybrid Cryo-EM, NMR, and Molecular Dynamics Approach

(2018) Kaiming Zhang et al.   STRUCTURE

cisTEM, user-friendly software for single-particle image processing

(2018) Timothy Grant et al.   eLife

Real-space refinement in PHENIX for cryo-EM and crystallography

(2018) Pavel V. Afonine et al.   Acta Crystallographica Section D-Structural Biology

New software tools in EMAN2 inspired by EMDatabank map challenge

(2018) James M. Bell et al.   JOURNAL OF STRUCTURAL BIOLOGY

Walking Forward with Kinesin

(2018) Eva Klinman et al.   TRENDS IN NEUROSCIENCES

Coiled-coil 1-mediated fastening of the neck and motor domains for kinesin-3 autoinhibition

(2018) Jinqi Ren et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

New tools for automated high-resolution cryo-EM structure determination in RELION-3

(2018) Jasenko Zivanov et al.   eLife

Structural basis for isoform-specific kinesin-1 recognition of Y-acidic cargo adaptors

(2018) Stefano Pernigo et al.   eLife

Insights into the Distinct Mechanisms of Action of Taxane and Non-Taxane Microtubule Stabilizers from Cryo-EM Structures

(2017) Elizabeth H. Kellogg et al.   JOURNAL OF MOLECULAR BIOLOGY

The TDH–GCN5L1–Fbxo15–KBP axis limits mitochondrial biogenesis in mouse embryonic stem cells

(2017) Valerio Donato et al.   NATURE CELL BIOLOGY

MotionCor2: anisotropic correction of beam-induced motion for improved cryo-electron microscopy

(2017) Shawn Q Zheng et al.   NATURE METHODS

cryoSPARC: algorithms for rapid unsupervised cryo-EM structure determination

(2017) Ali Punjani et al.   NATURE METHODS

A small-molecule activator of kinesin-1 drives remodeling of the microtubule network

(2017) Thomas S. Randall et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

UCSF ChimeraX: Meeting modern challenges in visualization and analysis

(2017) Thomas D. Goddard et al.   PROTEIN SCIENCE

Cryo-EM structure of haemoglobin at 3.2 Å determined with the Volta phase plate

(2017) Maryam Khoshouei et al.   Nature Communications

The divergent mitotic kinesin MKLP2 exhibits atypical structure and mechanochemistry

(2017) Joseph Atherton et al.   eLife

Role of Kif15 and its novel mitotic partner KBP in K-fiber dynamics and chromosome alignment

(2017) Nathalie Brouwers et al.   PLoS One

Kif1bp loss in mice leads to defects in the peripheral and central nervous system and perinatal death

(2017) Caroline S. Hirst et al.   Scientific Reports

Breaking Cryo-EM Resolution Barriers to Facilitate Drug Discovery

(2016) Alan Merk et al.   CELL

Kinesin-Binding Protein Controls Microtubule Dynamics and Cargo Trafficking by Regulating Kinesin Motor Activity

(2016) Josta T. Kevenaar et al.   CURRENT BIOLOGY

Kif1B Interacts with KBP to Promote Axon Elongation by Localizing a Microtubule Regulator to Growth Cones

(2016) C. M. Drerup et al.   JOURNAL OF NEUROSCIENCE

Gctf: Real-time CTF determination and correction

(2016) Kai Zhang   JOURNAL OF STRUCTURAL BIOLOGY

RaptorX-Property: a web server for protein structure property prediction

(2016) Sheng Wang et al.   NUCLEIC ACIDS RESEARCH

Motility and microtubule depolymerization mechanisms of the Kinesin-8 motor, KIF19A

(2016) Doudou Wang et al.   eLife

Goldberg-Shprintzen megacolon syndrome with associated sensory motor axonal neuropathy

(2015) Hormos Salimi Dafsari et al.   AMERICAN JOURNAL OF MEDICAL GENETICS PART A

JPred4: a protein secondary structure prediction server

(2015) Alexey Drozdetskiy et al.   NUCLEIC ACIDS RESEARCH

High-resolution structures of kinesin on microtubules provide a basis for nucleotide-gated force-generation

(2014) Zhiguo Shang et al.   eLife

Conserved mechanisms of microtubule-stimulated ADP release, ATP binding, and force generation in transport kinesins

(2014) Joseph Atherton et al.   eLife

CFEOM1-Associated Kinesin KIF21A Is a Cortical Microtubule Growth Inhibitor

(2013) Babet van der Vaart et al.   DEVELOPMENTAL CELL

KBP–cytoskeleton interactions underlie developmental anomalies in Goldberg–Shprintzen syndrome

(2013) Loïc Drévillon et al.   HUMAN MOLECULAR GENETICS

Structure of a kinesin–tubulin complex and implications for kinesin motility

(2013) Benoît Gigant et al.   NATURE STRUCTURAL & MOLECULAR BIOLOGY

Homozygous truncating mutation of the KBP gene, encoding a KIF1B-binding protein, in a familial case of fetal polymicrogyria

(2013) Stéphanie Valence et al.   NEUROGENETICS

High-resolution noise substitution to measure overfitting and validate resolution in 3D structure determination by single particle electron cryomicroscopy

(2013) Shaoxia Chen et al.   ULTRAMICROSCOPY

A comparative assessment and analysis of 20 representative sequence alignment methods for protein structure prediction

(2013) Renxiang Yan et al.   Scientific Reports

Mapping the Structural and Dynamical Features of Kinesin Motor Domains

(2013) Guido Scarabelli et al.   PLoS Computational Biology

The crystal structure and biochemical characterization of Kif15: a bifunctional molecular motor involved in bipolar spindle formation and neuronal development

(2013) Marta Klejnot et al.   ACTA CRYSTALLOGRAPHICA SECTION D-BIOLOGICAL CRYSTALLOGRAPHY

Fiji: an open-source platform for biological-image analysis

(2012) Johannes Schindelin et al.   NATURE METHODS

Structural and Functional Discussion of the Tetra-Trico-Peptide Repeat, a Protein Interaction Module

(2012) Natalie Zeytuni et al.   STRUCTURE

Fast, scalable generation of high-quality protein multiple sequence alignments using Clustal Omega

(2011) F. Sievers et al.   Molecular Systems Biology

Inscuteable and NuMA proteins bind competitively to Leu-Gly-Asn repeat-enriched protein (LGN) during asymmetric cell divisions

(2011) S. Culurgioni et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

KBP interacts with SCG10, linking Goldberg–Shprintzen syndrome to microtubule dynamics and neuronal differentiation

(2010) Maria M. Alves et al.   HUMAN MOLECULAR GENETICS

I-TASSER: a unified platform for automated protein structure and function prediction

(2010) Ambrish Roy et al.   Nature Protocols

Molecular Motors in Neurons: Transport Mechanisms and Roles in Brain Function, Development, and Disease

(2010) Nobutaka Hirokawa et al.   NEURON

MolProbity: all-atom structure validation for macromolecular crystallography

(2009) Vincent B. Chen et al.   ACTA CRYSTALLOGRAPHICA SECTION D-BIOLOGICAL CRYSTALLOGRAPHY

ATP Hydrolysis in Eg5 Kinesin Involves a Catalytic Two-water Mechanism

(2009) Courtney L. Parke et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Kinesin superfamily motor proteins and intracellular transport

(2009) Nobutaka Hirokawa et al.   NATURE REVIEWS MOLECULAR CELL BIOLOGY

Insights into anaphase promoting complex TPR subdomain assembly from a CDC26–APC6 structure

(2009) Jing Wang et al.   NATURE STRUCTURAL & MOLECULAR BIOLOGY

Fast and accurate automatic structure prediction with HHpred

(2009) Andrea Hildebrand et al.   PROTEINS-STRUCTURE FUNCTION AND BIOINFORMATICS

KBP is essential for axonal structure, outgrowth and maintenance in zebrafish, providing insight into the cellular basis of Goldberg-Shprintzen syndrome

(2008) D. A. Lyons et al.   DEVELOPMENT

Protein Structure Fitting and Refinement Guided by Cryo-EM Density

(2008) Maya Topf et al.   STRUCTURE