MeCP2 gates spatial learning-induced alternative splicing events in the mouse hippocampus

Neuronal ensemble-specific DNA methylation strengthens engram stability

(2020) Kubra Gulmez Karaca et al.   Nature Communications

Three-dimensional genome restructuring across timescales of activity-induced neuronal gene expression

(2020) Jonathan A. Beagan et al.   NATURE NEUROSCIENCE

Transcriptomic Analysis of Mecp2 Mutant Mice Reveals Differentially Expressed Genes and Altered Mechanisms in Both Blood and Brain

(2019) Albert Sanfeliu et al.   Frontiers in Psychiatry

MeCP2: A Critical Regulator of Chromatin in Neurodevelopment and Adult Brain Function

(2019) Kubra Gulmez Karaca et al.   INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES

Transcriptomic Studies in Mouse Models of Rett Syndrome: A Review

(2019) Albert Sanfeliu et al.   NEUROSCIENCE

N-terminal alternative splicing of GluN1 regulates the maturation of excitatory synapses and seizure susceptibility

(2019) Hong Liu et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Mimicking Age-Associated Gadd45γ Dysregulation Results in Memory Impairments in Young Adult Mice

(2019) David V.C. Brito et al.   JOURNAL OF NEUROSCIENCE

Control of Long-Term Synaptic Potentiation and Learning by Alternative Splicing of the NMDA Receptor Subunit GluN1

(2019) Ameet S. Sengar et al.   Cell Reports

Neuron-specific alternative splicing of transcriptional machineries: Implications for neurodevelopmental disorders

(2018) Robert S. Porter et al.   MOLECULAR AND CELLULAR NEUROSCIENCE

Rett syndrome: insights into genetic, molecular and circuit mechanisms

(2018) Jacque P. K. Ip et al.   NATURE REVIEWS NEUROSCIENCE

Adult hippocampal MeCP2 preserves the genomic responsiveness to learning required for long-term memory formation

(2018) Kubra Gulmez Karaca et al.   NEUROBIOLOGY OF LEARNING AND MEMORY

Activity-dependent aberrations in gene expression and alternative splicing in a mouse model of Rett syndrome

(2018) Sivan Osenberg et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Neuronal Chromatin Architecture Regulator CTCF Dictates Remote Memory

(2018) David V.C. Brito et al.   JOURNAL OF NEUROSCIENCE

Activity-Regulated Transcription: Bridging the Gap between Neural Activity and Behavior

(2018) Ee-Lynn Yap et al.   NEURON

Neuronal activity modifies the chromatin accessibility landscape in the adult brain

(2017) Yijing Su et al.   NATURE NEUROSCIENCE

Intron retention is regulated by altered MeCP2-mediated splicing factor recruitment

(2017) Justin J. -L. Wong et al.   Nature Communications

The neurogenetics of alternative splicing

(2016) Celine K. Vuong et al.   NATURE REVIEWS NEUROSCIENCE

Spatial genome organization and cognition

(2016) Prashanth Rajarajan et al.   NATURE REVIEWS NEUROSCIENCE

Contextual fear conditioning induces differential alternative splicing

(2016) Shane G. Poplawski et al.   NEUROBIOLOGY OF LEARNING AND MEMORY

Targeted Intron Retention and Excision for Rapid Gene Regulation in Response to Neuronal Activity

(2016) Oriane Mauger et al.   NEURON

P2X-mediated AMPA receptor internalization and synaptic depression is controlled by two CaMKII phosphorylation sites on GluA1 in hippocampal neurons

(2016) Johan-Till Pougnet et al.   Scientific Reports

Misregulation of Alternative Splicing in a Mouse Model of Rett Syndrome

(2016) Ronghui Li et al.   PLoS Genetics

Impermanence of dendritic spines in live adult CA1 hippocampus

(2015) Alessio Attardo et al.   NATURE

The alternative role of DNA methylation in splicing regulation

(2015) Galit Lev Maor et al.   TRENDS IN GENETICS

Age-Related Nuclear Translocation of P2X6 Subunit Modifies Splicing Activity Interacting with Splicing Factor 3A1

(2015) Juan Ignacio Díaz-Hernández et al.   PLoS One

Widespread intron retention in mammals functionally tunes transcriptomes

(2014) Ulrich Braunschweig et al.   GENOME RESEARCH

Neural Cell Adhesion Molecule NrCAM Regulates Semaphorin 3F-Induced Dendritic Spine Remodeling

(2014) G. P. Demyanenko et al.   JOURNAL OF NEUROSCIENCE

ATP P2X Receptors Downregulate AMPA Receptor Trafficking and Postsynaptic Efficacy in Hippocampal Neurons

(2014) Johan-Till Pougnet et al.   NEURON

Intragenic DNA methylation modulates alternative splicing by recruiting MeCP2 to promote exon recognition

(2013) Alika K Maunakea et al.   CELL RESEARCH

SUMOylation of MeCP2 is essential for transcriptional repression and hippocampal synapse development

(2013) Ju Cheng et al.   JOURNAL OF NEUROCHEMISTRY

Postnatal inactivation reveals enhanced requirement for MeCP2 at distinct age windows

(2012) Hélène Cheval et al.   HUMAN MOLECULAR GENETICS

Elimination of Dendritic Spines with Long-Term Memory Is Specific to Active Circuits

(2012) J. Sanders et al.   JOURNAL OF NEUROSCIENCE

MeCP2 Is Critical for Maintaining Mature Neuronal Networks and Global Brain Anatomy during Late Stages of Postnatal Brain Development and in the Mature Adult Brain

(2012) M. V. C. Nguyen et al.   JOURNAL OF NEUROSCIENCE

Tissue-Specific Alternative Splicing Remodels Protein-Protein Interaction Networks

(2012) Jonathan D. Ellis et al.   MOLECULAR CELL

Rescue of aging-associated decline in Dnmt3a2 expression restores cognitive abilities

(2012) Ana M M Oliveira et al.   NATURE NEUROSCIENCE

Differential gene and transcript expression analysis of RNA-seq experiments with TopHat and Cufflinks

(2012) Cole Trapnell et al.   Nature Protocols

The Impact of MeCP2 Loss- or Gain-of-Function on Synaptic Plasticity

(2012) Elisa S Na et al.   NEUROPSYCHOPHARMACOLOGY

Modulation of dendritic AMPA receptor mRNA trafficking by RNA splicing and editing

(2012) Luca La Via et al.   NUCLEIC ACIDS RESEARCH

Activity-regulated RNA editing in select neuronal subfields in hippocampus

(2012) Ales Balik et al.   NUCLEIC ACIDS RESEARCH

MATS: a Bayesian framework for flexible detection of differential alternative splicing from RNA-Seq data

(2012) Shihao Shen et al.   NUCLEIC ACIDS RESEARCH

Molecular and functional properties of P2X receptors—recent progress and persisting challenges

(2012) Karina Kaczmarek-Hájek et al.   Purinergic Signalling

Dynamic DNA methylation: a prime candidate for genomic metaplasticity and behavioral adaptation

(2012) Danay Baker-Andresen et al.   TRENDS IN NEUROSCIENCES

The Role of MeCP2 in the Brain

(2011) Jacky Guy et al.   Annual Review of Cell and Developmental Biology

SAM68 Regulates Neuronal Activity-Dependent Alternative Splicing of Neurexin-1

(2011) Takatoshi Iijima et al.   CELL

The role of NrCAM in neural development and disorders—Beyond a simple glue in the brain

(2011) Takeshi Sakurai   MOLECULAR AND CELLULAR NEUROSCIENCE

Cytoplasmic Intron Sequence-Retaining Transcripts Can Be Dendritically Targeted via ID Element Retrotransposons

(2011) Peter T. Buckley et al.   NEURON

Adult Neural Function Requires MeCP2

(2011) C. M. McGraw et al.   SCIENCE

Neuronal MeCP2 Is Expressed at Near Histone-Octamer Levels and Globally Alters the Chromatin State

(2010) Peter J. Skene et al.   MOLECULAR CELL

MeCP2 in the nucleus accumbens contributes to neural and behavioral responses to psychostimulants

(2010) Jie V Deng et al.   NATURE NEUROSCIENCE

Impaired sociability and cognitive function in Nrcam-null mice

(2009) Sheryl S. Moy et al.   BEHAVIOURAL BRAIN RESEARCH

Dendritic spine pathologies in hippocampal pyramidal neurons from Rett syndrome brain and after expression of Rett-associated MECP2 mutations

(2009) Christopher A. Chapleau et al.   NEUROBIOLOGY OF DISEASE

Ultrafast and memory-efficient alignment of short DNA sequences to the human genome

(2009) Ben Langmead et al.   GENOME BIOLOGY

MeCP2, a Key Contributor to Neurological Disease, Activates and Represses Transcription

(2008) M. Chahrour et al.   SCIENCE

The role of protein synthesis in memory consolidation: Progress amid decades of debate

(2007) Pepe J. Hernandez et al.   NEUROBIOLOGY OF LEARNING AND MEMORY